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  1. 1.   Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas
  2. Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Meehan, Robert S; Do, Khanh; Collins, Jerry M; Anderson, Larry; Ishii, Kazusa; Takebe, Naoko; Zlott, Jennifer; Juwara,Lamin; Piekarz, Richard; Streicher, Howard; Sharon, Elad; Rubinstein, Larry; Voth,Andrea; Lozier, Jay; Dull,Angie; Wilsker,Deborah; Hinoue, Toshinori; Laird, Peter W; Ferry-Galow,Katherine; Kinders,Robert; Parchment,Ralph; Doroshow,Jim; Chen, Alice P
  3. Oncotarget. 2020, Nov 03; 11(44): 3959-3971.
  1. 2.   Advances in using PARP inhibitors to treat cancer
  2. Kummar, S.; Chen, A.; Parchment, R. E.; Kinders, R. J.; Ji, J.; Tomaszewski, J. E.; Doroshow, J. H.
  3. Bmc Medicine. 2012, Mar; 10
  1. 3.   4 '-C-Methyl-2 '-Deoxyadenosine and 4 '-C-Ethyl-2 '-Deoxyadenosine Inhibit HIV-1 Replication
  2. Vu, B. C.; Boyer, P. L.; Siddiqui, M. A.; Marquez, V. E.; Hughes, S. H.
  3. Antimicrobial Agents and Chemotherapy. 2011, May; 55(5): 2379-2389.
  1. 4.   Mechanisms of HIV-1 drug resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors
  2. Nikolenko, G. N.; Kotelkin, A. T.; Oreshkova, S. F.; Ilyichev, A. A.
  3. Molecular Biology. 2011, Feb; 45(1): 93-109.
  1. 5.   Selective Modulation of DNA Polymerase Activity by Fixed-Conformation Nucleoside Analogues
  2. Eoff, R. L.; McGrath, C. E.; Maddukuri, L.; Salamanca-Pinzon, S. G.; Marquez, V. E.; Marnett, L. J.; Guengerich, F. P.; Egli, M.
  3. Angewandte Chemie-International Edition. 2010, Oct 4; 49(41): 7481-7485.
  1. 6.   Structural basis of HIV-1 resistance to AZT by excision
  2. Tu, X. Y.; Das, K.; Han, Q. W.; Bauman, J. D.; Clark, A. D.; Hou, X. R.; Frenkel, Y. V.; Gaffney, B. L.; Jones, R. A.; Boyer, P. L.; Hughes, S. H.; Sarafianos, S. G.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2010, Oct; 17(10): 1202-+.
  1. 7.   The odyssey of marine pharmaceuticals: a current pipeline perspective
  2. Mayer, A. M. S.; Glaser, K. B.; Cuevas, C.; Jacobs, R. S.; Kem, W.; Little, R. D.; McIntosh, J. M.; Newman, D. J.; Potts, B. C.; Shuster, D. E.
  3. Trends in Pharmacological Sciences. 2010, Jun; 31(6): 255-265.
  1. 8.   Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids
  2. Seiple, L. A.; Cardellina, J. H.; Akee, R.; Stivers, J. T.
  3. Molecular Pharmacology. 2008 73(3): 669-677.
  1. 9.   The nucleoside analogs 4 ' C-Methyl thymidine and 4 ' C-Ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants
  2. Boyer, P. L.; Julias, J. G.; Ambrose, Z.; Siddiqui, M. A.; MarqueZ, V. E.; Hughes, S. H.
  3. Journal of Molecular Biology. 2007, Aug; 371(4): 873-882.
  1. 10.   Mutations in the connection domain of HIV-1 reverse transcriptase increase 3 '-azido-3 '-deoxythymidine resistance
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Fivash, M. J.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Jan; 104(1): 317-322.
  1. 11.   Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells
  2. Brantley, E.; Antony, S.; Kohlhagen, G.; Meng, L. H.; Agama, K.; Stinson, S. F.; Sausville, E. A.; Pommier, Y.
  3. Cancer Chemotherapy and Pharmacology. 2006, Jul; 58(1): 62-72.
  1. 12.   Long homopurine center dot homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region
  2. Bacolla, A.; Collins, J. R.; Gold, B.; Chuzhanova, N.; Yi, M.; Stephens, R. M.; Stefanov, S.; Olsh, A.; Jakupciak, J. P.; Dean, M.; Lempicki, R. A.; Cooper, D. N.; Wells, R. D.
  3. Nucleic Acids Research. 2006 34(9): 2663-2675.
  1. 13.   Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O-6-benzylguanine
  2. Fishel, M. L.; Ganicsik, M. P.; Delaney, S. M.; Zuhowski, E. G.; Maher, V. M.; Karrison, T.; Moschel, R. C.; Egorin, M. J.; Dolan, M. E.
  3. Cancer Chemotherapy and Pharmacology. 2005, APR; 55(4): 333-342.
  1. 14.   Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells
  2. Pengt, B.; Hodge, D. R.; Thomas, S. B.; Cherry, J. M.; Munroe, D. J.; Pompeia, C.; Xiao, W. H.; Farrar, W. L.
  3. Journal of Biological Chemistry. 2005, FEB 11; 280(6): 4182-4187.
  1. 15.   Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 8; 102(6): 2093-2098.
  1. 16.   Intra- and intercellular variations in the repair efficiency of O-6-methylguanine, and their contribution to kinetic complexity
  2. Souliotis, V. L.; Sfikakis, P. P.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2004, DEC 21; 568(2): 155-170.
  1. 17.   Effects of the Delta 67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision
  2. Boyer, P. L.; Imamichi, T.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, SEP; 78(18): 9987-9997.
  1. 18.   Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
  2. Tuske, S.; Sarafianos, S. G.; Clark, A. D.; Ding, J. P.; Naeger, L. K.; White, K. L.; Miller, M. D.; Gibbs, C. S.; Boyer, P. L.; Clark, P.; Wang, G.; Gaffney, B. L.; Jones, R. A.; Jerina, D. M.; Hughes, S. H.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2004 11(5): 469-474.
  1. 19.   The Rad27 (Fen-1) nuclease inhibits Ty1 mobility in Saccharomyces cerevisiae
  2. Sundararajan, A.; Lee, B. S.; Garfinkel, D. J.
  3. Genetics. 2003 163(1): 55-67.
  1. 20.   Trapping HIV-1 reverse transcriptase before and after translocation on DNA
  2. Sarafianos, S. G.; Clark, A. D.; Tuske, S.; Squire, C. J.; Das, K.; Sheng, D. Q.; Ilankumaran, P.; Ramesha, A. R.; Kroth, H.; Sayer, J. M.; Jerina, D. M.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Journal of Biological Chemistry. 2003 278(18): 16280-16288.
  1. 21.   Enhancement of platinum-induced cytotoxicity by O-6- Benzylguanine
  2. Fishel, M. L.; Delaney, S. M.; Friesen, L. D.; Hansen, R. J.; Zuhowski, E. G.; Moschel, R. C.; Egorin, M. J.; Dolan, M. E.
  3. Molecular Cancer Therapeutics. 2003 2(7): 633-640.
  1. 22.   Error-prone DNA polymerases: When making a mistake is the only way to get ahead
  2. Rattray, A. J.; Strathern, J. N.
  3. Annual Review of Genetics. 2003 37: 31-66.
  1. 23.   Structures of HIV-1 reverse transcriptase with pre- and post- translocation AZTMP-terminated DNA
  2. Sarafianos, S. G.; Clark, A. D.; Das, K.; Tuske, S.; Birktoft, J. J.; Ilankumaran, P.; Ramesha, A. R.; Sayer, J. M.; Jerina, D. M.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Embo Journal. 2002 21(23): 6614-6624.
  1. 24.   The roles of REV3 and RAD57 in double-strand-break-repair- induced mutagenesis of Saccharomyces cerevisiae
  2. Rattray, A. J.; Shafer, B. K.; McGill, C. B.; Strathern, J. N.
  3. Genetics. 2002 162(3): 1063-1077.
  1. 25.   The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function
  2. Khan, S. G.; Muniz-Medina, V.; Shahlavi, T.; Baker, C. C.; Inui, H.; Ueda, T.; Emmert, S.; Schneider, T. D.; Kraemer, K. H.
  3. Nucleic Acids Research. 2002 30(16): 3624-3631.
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