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  1. 1.   Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib
  2. Pang, Ying; Li, Qi; Sergi, Zach; Yu, Guangyang; Kim, Olga; Lu, Peng; Chan, Marina; Sang, Xueyu; Wang, Herui; Ranjan, Alice; Robey, Robert W; Soheilian, Ferri; Tran,Bao; Núñez, Felipe J; Zhang, Meili; Song, Hua; Zhang, Wei; Davis, Dionne; Gilbert, Mark R; Gottesman, Michael M; Liu, Zhenggang; Thomas, Craig J; Castro, Maria G; Gujral, Taranjit S; Wu, Jing
  3. iScience. 2025, Apr 18; 28(4): 112283.
  1. 2.   CDK2 Inhibition Produces a Persistent Population of Polyploid Cancer Cells
  2. Tyutyunyk-Massey, Liliya; Chen,Zibo; Liu,Xiuxia; Kawakami, Masanori; Harned,Adam; Ng, Yeap; Harned,Adam; Okpechi,Samuel; Ogunlade,Blessing; Alfaro Mora,Yair; Weigert, Roberto; Narayan,Kedar; Liu,Xi; Dmitrovsky,Ethan
  3. JCI Insight. 2025, Apr 15;
  1. 3.   Developmental onset of planarian whole-body regeneration depends on axis reset
  2. Booth, Clare L T; Stevens, Brian C; Stubbert, Clover A; Kallgren,Neil; Deihl,Ennis; Davies,Erin
  3. Current Biology : CB. 2025, Apr 11;
  1. 4.   Ror gamma t-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
  2. Rodrigues, Patrick Fernandes; Wu, Shitong; Trsan, Tihana; Panda, Santosh K; Fachi, José Luís; Liu, Yizhou; Du, Siling; de Oliveira, Sarah; Antonova, Alina Ulezko; Khantakova, Darya; Sudan, Raki; Desai, Pritesh; Diamond, Michael S; Gilfillan, Susan; Anderson,Stephen; Cella, Marina; Colonna, Marco
  3. Cell. 2025, Apr 01;
  1. 5.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 6.   PLS-a-GalCer: a novel targeted glycolipid therapy for solid tumors
  2. Burks, Julian; Tiwary, Shweta; Stevens, David M; Skoczen,Sarah; Kularatne,Ruvanthi Nilanga; Stern,Stephan; Berzofsky, Jay A
  3. Journal for Immunotherapy of Cancer. 2025, Mar 22; 13(3):
  1. 7.   PRGN-2009 and bintrafusp alfa for patients with advanced or metastatic human papillomavirus-associated cancer
  2. Floudas, Charalampos S; Goswami, Meghali; Donahue, Renee N; Strauss, Julius; Pastor, Danielle M; Redman, Jason M; Brownell, Isaac; Turkbey, Evrim B; Steinberg, Seth M; Cordes, Lisa M; Marté, Jennifer L; Khan, Maheen H; McMahon, Sheri; Lamping, Elizabeth; Manu,Michell; Manukyan,Manuk; Brough, Douglas E; Lankford, Amy; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L
  3. Cancer Immunology, Immunotherapy : CII. 2025, Mar 21; 74(5): 155.
  1. 8.   Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
  2. Cho, Charles J; Nguyen, Thanh; Rougeau, Amala K; Huang, Yang-Zhe; To, Sarah; Lin, Xiaobo; Thalalla Gamage,Supuni; Meier,Jordan; Mills, Jason C
  3. Cellular and Molecular Gastroenterology and Hepatology. 2025, Mar 11; 101496.
  1. 9.   Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection
  2. Happe, Myra; Lynch, Rebecca M; Fichtenbaum, Carl J; Heath, Sonya L; Koletar, Susan L; Landovitz, Raphael J; Presti, Rachel M; Santana-Bagur, Jorge L; Tressler, Randall L; Holman, LaSonji A; Novik, Laura; Roa, Jhoanna C; Rothwell, Ro Shauna; Strom, Larisa; Wang,Jing; Hu, Zonghui; Conan-Cibotti, Michelle; Bhatnagar, Anjali M; Dwyer, Bridget; Ko, Sung Hee; Belinky, Frida; Namboodiri, Aryan M; Pandey, Janardan P; Carroll, Robin; Basappa, Manjula; Serebryannyy, Leonid; Narpala, Sandeep R; Lin, Bob C; McDermott, Adrian B; Boritz, Eli A; Capparelli, Edmund V; Coates, Emily E; Koup, Richard A; Ledgerwood, Julie E; Mascola, John R; Chen, Grace L; Tebas, Pablo
  3. JCI Insight. 2025, Feb 24; 10(4):
  1. 10.   Histidine Tag-Specific PEGylation Improves the Circulating Half-Life of TIMP2
  2. Toor, Jack; Grabowska, Wiktoria R; Johnson, Adam L; Jones,Jane; Stetler-Stevenson, William G; Khalili, Hanieh; Peeney, David
  3. ACS Applied Bio Materials. 2025, Feb 21;
  1. 11.   Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
  2. Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S; Cho, May; Davis, Elizabeth J; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das,Bishu; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; LoRusso, Patricia M
  3. Cancer. 2025, Feb 15; 131(4): e35755.
  1. 12.   Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350
  2. Joyce, M Gordon; Bu, Wei; Chen, Wei-Hung; Gillespie, Rebecca A; Andrews, Sarah F; Wheatley, Adam K; Tsybovsky,Yaroslav; Jensen, Jaime L; Stephens,Tyler; Prabhakaran, Madhu; Fisher, Brian E; Narpala, Sandeep R; Bagchi, Meghna; McDermott, Adrian B; Nabel, Gary J; Kwong, Peter D; Mascola, John R; Cohen, Jeffrey I; Kanekiyo, Masaru
  3. Immunity. 2025, Feb 11; 58(2): 295-308.e5. .
  1. 13.   Modulation of the Substrate Preference of a MYST Acetyltransferase by a Scaffold Protein
  2. Sengupta, Raghuvir N; Brodsky, Oleg; Bingham, Patrick; Diehl, Wade C; Ferre, RoseAnn; Greasley, Samantha E; Johnson, Eric; Kraus, Michelle; Lieberman, Whitney; Meier,Jordan; Paul, Thomas A; Maegley, Karen A
  3. The Journal of Biological Chemistry. 2025, Feb 03; 108262.
  1. 14.   Longitudinal single-cell profiles of lung regeneration after viral infection reveal persistent injury-associated cell states
  2. Niethamer, Terren K; Planer, Joseph D; Morley, Michael P; Babu, Apoorva; Zhao, Gan; Basil, Maria C; Cantu, Edward; Frank, David B; Diamond, Joshua M; Nottingham, Ana N; Li, Shanru; Sharma,Arnav; Hallquist, Hannah; Levin, Lillian I; Zhou, Su; Vaughan, Andrew E; Morrisey, Edward E
  3. Cell Stem Cell. 2025, Jan 13;
  1. 15.   Aberrant Wnt/ß-catenin signaling in the mesenchymal stem cells of LZTFL1-depleted mice leads to increased adipogenesis, with implications for obesity
  2. Badralmaa,Yunden; Natarajan,Ven
  3. The Journal of Biological Chemistry. 2024, Dec 09; 108057.
  1. 16.   Affinity Tag-Free Purification of SARS-CoV-2 N Protein and Its Crystal Structure in Complex with ssDNA
  2. Maiti,Atanu; Matsuo,Hiroshi
  3. Biomolecules. 2024, Nov 30; 14(12):
  1. 17.   Adoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen spreading and elimination of antigen-negative tumor variants
  2. Zhang, Ling; Norberg, Scott M; Karimipour, Farrah; Davies, John S; Kuznetsov, Alex; Lassoued, Wiem; Burnett, Daniel; Homan,Philip; Cam, Margaret; Sinkoe, Andrew; Xue, Ping; Gulley, James L; Hinrichs, Christian S
  3. Journal for Immunotherapy of Cancer. 2024, Nov 18; 12(11):
  1. 18.   Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of OXi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents
  2. Vairin, Rebecca; Tamminga, Caleb; Shi, Zhe; Borchardt, Christian; Jambulapati, Jayaram; Bai, Ruoli; Wanniarachchi, Hashini; Bueno, Lorena; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2024, Nov 07; 118: 117981.
  1. 19.   Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity
  2. Hangasky, John A; Fernández, Rocío Del Valle; Stellas,Dimitris; Hails, Guillermo; Karaliota,Sevasti; Ashley, Gary W; Felber,Barbara; Pavlakis,George; Santi, Daniel V
  3. Frontiers in Immunology. 2024, Nov 4; 15: 1458145.
  1. 20.   Perplexing paradoxical reactions: navigating the complexity of protracted tuberculosis meningitis-a case report
  2. Gooding,Megan; Hammoud, Dima A; Epling, Brian; Rocco, Joseph; Laidlaw, Elizabeth; Kuriakose,Safia; Chaturvedi, Mansi; Galindo, Frances; Ma, Stella V; Mystakelis, Harry; Poole, April; Russo, Kelly; Shah, Maunank; Malone, Joseph L; Rupert,Adam; Sereti, Irini; Manion, Maura
  3. Frontiers in Immunology. 2024, Oct 31; 15: 1441945.
  1. 21.   Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial
  2. Davar, Diwakar; Morrison, Robert M; Dzutsev, Amiran K; Karunamurthy, Arivarasan; Chauvin, Joe-Marc; Amatore, Florent; Deutsch, Julie S; Das Neves, Rodrigo X; Rodrigues,Richard; McCulloch, John A; Wang, Hong; Hartman, Douglas J; Badger, Jonathan H; Fernandes, Miriam R; Bai, Yulong; Sun, Jie; Cole, Alicia M; Aggarwal, Poonam; Fang, Jennifer R; Deitrick, Christopher; Bao, Riyue; Duvvuri, Umamaheswar; Sridharan, Shaum S; Kim, Seungwon W; A Choudry, Haroon; Holtzman, Matthew P; Pingpank, James F; O'Toole, James Patrick; DeBlasio, Richelle; Jin, Yang; Ding, Quanquan; Gao, Wentao; Groetsch, Christopher; Pagliano, Ornella; Rose, Amy; Urban, Corey; Singh, Jagjit; Divarkar, Prajan; Mauro, David; Bobilev, Dmitri; Wooldridge, James; Krieg, Arthur M; Fury, Matthew G; Whiteaker, Jeffrey R; Zhao, Lei; Paulovich, Amanda G; Najjar, Yana G; Luke, Jason J; Kirkwood, John M; Taube, Janis M; Park, Hyun Jung; Trinchieri, Giorgio; Zarour, Hassane M
  3. Cancer Cell. 2024, Oct 30;
  1. 22.   Multi-objective latent space optimization of generative molecular design models
  2. Abeer, A N M Nafiz; Urban, Nathan M; Weil,Michael; Alexander, Francis J; Yoon, Byung-Jun
  3. Patterns (New York, N.Y.). 2024, Oct 11; 5(10): 101042.
  1. 23.   ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models
  2. Schmid, Sebastian; Russell, Zachary R; Shimura Yamashita,Alex; West, Madeline E; Parrish, Abigail G; Walker, Julia; Rudoy, Dmytro; Yan, James Z; Quist, David C; Gessesse, Betemariyam N; Alvinez, Neriah; Hill, Kimberly D; Anderson,Larry; Cimino, Patrick J; Kumasaka, Debra K; Parchment,Ralph; Holland, Eric C; Szulzewsky, Frank
  3. Cell Reports. 2024, Oct 03; 43(10): 114829.
  1. 24.   Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal
  2. Rink,Connie; Kroupa, Tomas; Rein,Alan; Datta,Siddhartha
  3. Viruses. 2024, Sep 25; 16(10): 1517.
  1. 25.   Glycemic Control in Diabetic Patients Improved Overall Lung Cancer Survival across Diverse Populations
  2. Wu, Yi-Hung; Luke,Brian; Wu, Xiao-Cheng; Lee, J Jack; Yi, Yong; Okpechi,Samuel; Gause,Barry; Mehta, Paras; Sherman, Steven I; Ochoa, Augusto; Dmitrovsky,Ethan; Liu,Xi
  3. JNCI Cancer Spectrum. 2024, Sep 12;
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