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  1. 1.   Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator
  2. Jenkins, Lisa M. Miller; Paine, Elliott L.; Deshmukh, Lalit; Nikolayevskiy, Herman; Lyons, Gaelyn C.; Scerba, Michael T.; Rosenker, Kara George; Luecke, Hans F.; Louis, John M.; Chertova,Elena; Gorelick,Robert; Ott,David; Clore, G. Marius; Appella, Daniel H.
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2019, MAY 22; 141(20): 8327-8338.
  1. 2.   N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
  2. Gal, N.; Kolusheva, S.; Kedei, N.; Telek, A.; Naeem, T. A.; Lewin, N. E.; Lim, L.; Mannan, P.; Garfield, S. H.; El Kazzouli, S.; Sigano, D. M.; Marquez, V. E.; Blumberg, P. M.; Jelinek, R.
  3. Chembiochem. 2011, Oct; 12(15): 2331-2340.
  1. 3.   Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer
  2. Jenkins, L. M. M.; Ott, D. E.; Hayashi, R.; Coren, L. V.; Wang, D. Y.; Xu, Q.; Schito, M. L.; Inman, J. K.; Appella, D. H.; Appella, E.
  3. Nature Chemical Biology. 2010, Dec; 6(12): 887-889.
  1. 4.   Antineoplastic Agents. 565. Synthesis of Combretastatin D-2 Phosphate and Dihydro-combretastatin D-2
  2. Pettit, G. R.; Quistorf, P. D.; Fry, J. A.; Herald, D. L.; Hamel, E.; Chapuis, J. C.
  3. Journal of Natural Products. 2009 72(5): 876-883.
  1. 5.   Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities
  2. Duan, D.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Kedei, N.; Peach, M. L.; Lee, J.; Abeyweera, T. P.; Rotenberg, S. A.; Kim, H.; Kim, Y. H.; El Kazzouli, S.; Chung, J. U.; Young, H. A.; Young, M. R.; Baker, A.; Colburn, N. H.
  3. Journal of Medicinal Chemistry. 2008 51(17): 5198-5220.
  1. 6.   Conformationally constrained analogues of diacylglycerol. 30. An investigation of diacylglycerol-lactones containing heteroaryl groups reveals compounds with high selectivity for Ras guanyl nucleotide-releasing proteins
  2. El Kazzouli, S.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2008 51(17): 5371-5386.
  1. 7.   Stereoselective synthesis of 3,3-diarylacrylonitriles as tubulin polymerization inhibitors
  2. Fang, Z. L.; Song, Y. L.; Sarkar, T.; Hamel, E.; Fogler, W. E.; Agoston, G. E.; Fanwick, P. E.; Cushman, M.
  3. Journal of Organic Chemistry. 2008 73(11): 4241-4244.
  1. 8.   Synthesis and applications of novel bis(ammonium) chiral ionic liquids derived from isomannide
  2. Kumar, V.; Olsen, C. E.; Schaffer, S. J. C.; Parmar, V. S.; Malhotra, S. V.
  3. Organic Letters. 2007, Sep; 9(20): 3905-3908.
  1. 9.   Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma
  2. Daugherty, S. E.; Platz, E. A.; Shugart, Y. Y.; Fallin, M. D.; Isaacs, W. B.; Chatterjee, N.; Welch, R.; Huang, W. Y.; Hayes, R. B.
  3. Cancer Epidemiology Biomarkers & Prevention. 2007, Aug; 16(8): 1536-1542.
  1. 10.   Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups
  2. Malolanarasimhan, K.; Kedei, N.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Surawski, R. J.; Pavlyukovets, V. A.; Garfield, S. H.; Wincovitch, S.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2007, Mar; 50(5): 962-978.
  1. 11.   Antitumor agents. Part 236: Synthesis of water-soluble colchicine derivatives
  2. Nakagawa-Goto, K.; Chen, C. X.; Hamel, E.; Wu, C. C.; Bastow, K. F.; Brossi, A.; Lee, K. H.
  3. Bioorganic & Medicinal Chemistry Letters. 2005, JAN 3; 15(1): 235-238.
  1. 12.   Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
  2. Tamamura, H.; Sigano, D. M.; Lewin, N. E.; Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, SEP 23; 47(20): 4858-4864.
  1. 13.   Enantioselective synthesis of (S)-3-carboxy-4-((carboxy)difluoromethyl)phenylalanine in protected form and its incorporation into a PTP-1B-directed tripeptide
  2. Kang, S. U.; Yang, G.; Li, W.; Zhang, Z. Y.; Burke, T. R.
  3. Chemistry & Biodiversity. 2004 1(4): 626-633.
  1. 14.   The discovery of thiazole-4-carboxamide adenine dinucleotide (TAD) and a recent synthetic approach for the construction of a hydrolytically resistant surrogate
  2. Marquez, V. E.
  3. Inosine Monophosphate Dehydrogenase: A Major Therapeutic Target. 2003; 839 : 198-210.
  1. 15.   Rational design of drugs that induce human immunodeficiency virus replication
  2. Hamer, D. H.; Bocklandt, S.; McHugh, L.; Chun, T. W.; Blumberg, P. M.; Sigano, D. M.; Marquez, V. E.
  3. Journal of Virology. 2003 77(19): 10227-10236.
  1. 16.   Synthesis, resolution, and determination of the absolute configuration of the enantiomers of cis-4,5-dihydroxy-1,2- dithiane 1,1-dioxide, an HIV-1NCp7 inhibitor
  2. Mayasundari, A.; Rice, W. G.; Diminnie, J. B.; Baker, D. C.
  3. Bioorganic & Medicinal Chemistry. 2003 11(14): 3215-3219.
  1. 17.   Antineoplastic agents 460. Synthesis of combretastatin A-2 prodrugs
  2. Pettit, G. R.; Moser, B. R.; Boyd, M. R.; Schmidt, J. M.; Pettit, R. K.; Chapuis, J. C.
  3. Anti-Cancer Drug Design. 2001 16(4-5): 185-193.
  1. 18.   The influence of natural products upon drug discovery
  2. Newman, D. J.; Cragg, G. M.; Snader, K. M.
  3. Natural Product Reports. 2000 17(3): 215-234.
  1. 19.   Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation
  2. Jansen, A. P.; Colburn, N. H.; Verma, A. K.
  3. Oncogene. 1999 18(42): 5806-5813.
  1. 20.   Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion
  2. Young, M. R.; Li, J. J.; Rincon, M.; Flavell, R. A.; Sathyanarayana, B. K.; Hunziker, R.; Colburn, N.
  3. Proceedings of the National Academy of Sciences of the United States of America. 1999 96(17): 9827-9832.
  1. 21.   A Convergent Total Synthesis of the Michellamines
  2. Bringmann, G.; Gotz, R.; Keller, P. A.; Walter, R.; Boyd, M. R.; Lang, F. R.; Garcia, A.; Walsh, J. J.; Tellitu, I.; Bhaskar, K. V.; Kelly, T. R.
  3. Journal of Organic Chemistry. 1998 63(4): 1090-1097.
  1. 22.   Shortage of Mitogen-Activated Protein Kinase Is Responsible For Resistance to Ap-1 Transactivation and Transformation in Mouse Jb6 Cells
  2. Huang, C. S.; Ma, W. Y.; Young, M. R.; Colburn, N.; Dong, Z. G.
  3. Proceedings of the National Academy of Sciences of the United States of America. 1998 95(1): 156-161.
  1. 23.   Differential Expression and Activity of Phosphatases and Protein Kinases in Adriamycin Sensitive and Resistant Human Breast Cancer Mcf-7 Cells
  2. Ratnasinghe, D.; Phang, J. M.; Yeh, G. C.
  3. International Journal of Oncology. 1998 13(1): 79-84.
  1. 24.   Antineoplastic agents 393. Synthesis of the trans-isomer of combretastatin A-4 prodrug
  2. Pettit, G. R.; Rhodes, M. R.; Herald, D. L.; Chaplin, D. J.; Stratford, M. R. L.; Hamel, E.; Pettit, R. K.; Chapuis, J. C.; Oliva, D.
  3. Anti-Cancer Drug Design. 1998 13(8): 981-993.
  1. 25.   The Antineoplastic Agent Bryostatin-1 Induces Proinflammatory Cytokine Production in Human Monocytes - Synergy With Interleukin-2 and Modulation of Interleukin-2r-Gamma Chain Expression
  2. Bosco, M. C.; Rottschafer, S.; Taylor, L. S.; Ortaldo, J. R.; Longo, D. L.; Espinozadelgado, I.
  3. Blood. 1997 89(9): 3402-3411.
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