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  1. 1.   Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain
  2. Spuches, A. M.; Argiros, H. J.; Lee, K. H.; Haas, L. L.; Perch, S. C.; Krag, D. N.; Roller, P. P.; Wilcox, D. E.; Lyons, B. A.
  3. Journal of Molecular Recognition. 2007, Jul-Aug; 20(4): 245-252.
  1. 2.   Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics
  2. Jiang, S.; Li, P.; Peach, M. L.; Bindu, L.; Worthy, K. W.; Fisher, R. J.; Burke, T. R.; Nicklaus, M.; Roller, P. P.
  3. Biochemical and Biophysical Research Communications. 2006, Oct; 349(2): 497-503.
  1. 3.   Design and concise synthesis of fully protected analogues of L-gamma-carboxyglutamic acid
  2. Jiang, S.; Li, P.; Lai, C. C.; Kelley, J. A.; Roller, P. P.
  3. Journal of Organic Chemistry. 2006, Sep; 71(19): 7307-7314.
  1. 4.   A practical synthesis of fully protected L-gamma-carboxyglutamic acid
  2. Jiang, S.; Lai, C. C.; Kelley, J. A.; Roller, P. P.
  3. Tetrahedron Letters. 2006, Jan; 47(1): 23-25.
  1. 5.   Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin
  2. Shi, Y. H.; Song, Y. L.; Lin, D. H.; Tan, J. Z.; Roller, P. P.; Li, Q.; Long, Y. Q.; Song, G. Q.
  3. Biochemical and Biophysical Research Communications. 2005, MAY 20; 330(4): 1254-1261.
  1. 6.   Small nonphosphorylated Grb2-SH2 domain antagonists evaluated by surface resonance plasmon technology
  2. Lung, F. D. T.; Chang, C. W.; Chong, M. C.; Liou, C. C.; Li, P.; Peach, M. L.; Nicklaus, M. C.; Lou, B. S.; Roller, P. P.
  3. Peptide Science (Biopolymers). 2005 80(5): 628-635.
  1. 7.   A one-step synthesis of N-alpha-Fmoc-4-O-[O ',O ''-di-tert-butyl-2-(2-fluoromalonyl)]-L-tyrosine from commercially available starting material
  2. Kang, S. U.; Burke, T. R.
  3. Tetrahedron Letters. 2004, NOV 15; 45(47): 8611-8613.
  1. 8.   Development of L-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity
  2. Song, Y. L.; Roller, P. P.; Long, Y. Q.
  3. Bioorganic & Medicinal Chemistry Letters. 2004 14(12): 3205-3208.
  1. 9.   Design and synthesis of potent Grb2-SH2 domain antagonists based upon phage library derived cyclic peptide G1TE
  2. Li, P.; Zhang, M. C.; Peach, M. L.; Yang, D. J.; Roller, P. P.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 2): U192-U192.
  1. 10.   Design and synthesis of a beta-amino phosphotyrosyl mimetic suitably protected for peptide synthesis
  2. Lee, K.; Zhang, M. C.; Yang, D. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2002 12(23): 3399-3401.
  1. 11.   Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7
  2. Pero, S. C.; Oligino, L.; Daly, R. J.; Soden, A. L.; Liu, C.; Roller, P. P.; Li, P.; Krag, D. N.
  3. Journal of Biological Chemistry. 2002 277(14): 11918-11926.
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