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  1. 1.   Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
  2. Das, Arundhoti; Martinez-Ruiz, Gustavo Ulises; Bouladoux, Nicolas; Stacy, Apollo; Moraly, Josquin; Vega-Sendino, Maria; Zhao, Yongge; Lavaert, Marieke; Ding, Yi; Morales-Sanchez, Abigail; Harly, Christelle; Seedhom, Mina O; Chari,Raj; Awasthi, Parirokh; Ikeuchi, Tomoko; Wang, Yueqiang; Zhu, Jinfang; Moutsopoulos, Niki M; Chen, WanJun; Yewdell, Jonathan W; Shapiro, Virginia Smith; Ruiz, Sergio; Taylor, Naomi; Belkaid, Yasmine; Bhandoola, Avinash
  3. Immunity. 2024, May 14; 57(5): 1019-1036.
  1. 2.   Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis
  2. Saxena, Kritika; Jolly, Mohit Kumar; Kuppusamy,Balamurugan
  3. Translational oncology. 2020, NOV; 13(11):
  1. 3.   Vav1 is Essential for HIF-1a Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
  2. Hong,Jaewoo; Min,Yongfen; Wuest, Todd; Lin,Charles
  3. Cancers. 2020, JUN; 12(6): E1374.
  1. 4.   The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1 alpha and Glut-1 Expression and Glucose Uptake in the Brain
  2. Hong,Jaewoo; Kim, Yurim; Yanpallewar,Sudhirkumar; Lin,Charles
  3. International journal of molecular sciences. 2020, FEB; 21(4):
  1. 5.   Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
  2. Baseler, Walter; Davies, Luke; Quigley, L.; Ridnour, Lisa; Weiss, Jonathan; Hussain, S. P.; Wink, David; McVicar, Daniel
  3. Redox biology. 2016, Dec; 10: 12-23.
  1. 6.   C/EBP-delta regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1 alpha
  2. Min, Y.; Ghose, S.; Boelte, K.; Li, J.; Yang, L.; Lin, P. C.
  3. Oncogene. 2011, Dec; 30(49): 4901-4909.
  1. 7.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 8.   Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads
  2. Rapisarda, A.; Shoemaker, R. H.; Melillo, G.
  3. Cell Cycle. 2009, Dec; 8(24): 4040-4043.
  1. 9.   Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome
  2. Tandle, A. T.; Calvani, M.; Uranchimeg, B.; Zahavi, D.; Melillo, G.; Libutti, S. K.
  3. Experimental Cell Research. 2009 315(11): 1850-1859.
  1. 10.   Hypoxia-inducible factor-1 target genes as indicators of tumor vessel response to vascular endothelial growth factor inhibition
  2. Dang, D. T.; Chun, S. Y.; Burkitt, K.; Abe, M.; Chen, S.; Havre, P.; Mabjeesh, N. J.; Heath, E. I.; Vogelzang, N. J.; Cruz-Correa, M.; Blayney, D. W.; Ensminger, W. D.; Croix, B. S.; Dang, N. H.; Dang, L. H.
  3. Cancer Research. 2008 68(6): 1872-1880.
  1. 11.   UVC inhibits HIF-1 alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
  2. Rapisarda, A.; Melillo, G.
  3. Oncogene. 2007, Oct; 26(48): 6875-6884.
  1. 13.   The role of ascorbate in the modulation of HIF-1 alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II)
  2. Kaczmarek, M.; Timofeeva, O. A.; Karaczyn, A.; Malyguine, A.; Kasprzak, K. S.; Salnikow, K.
  3. Free Radical Biology and Medicine. 2007, Apr; 42(8): 1246-1257.
  1. 14.   Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1 alpha protein accumulation by NSC 644221
  2. Creighton-Gutteridge, M.; Cardellina, J. H.; Stephen, A. G.; Rapisarda, A.; Uranchimeg, B.; Hite, K.; Denny, W. A.; Shoemaker, R. H.; Melillo, G.
  3. Clinical Cancer Research. 2007, Feb; 13(3): 1010-1018.
  1. 15.   Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13
  2. Ivanov, S. V.; Salnikow, K.; Ivanova, A. V.; Bai, L.; Lerman, M. I.
  3. Oncogene. 2007, Feb; 26(6): 802-812.
  1. 16.   Identification of a new natural camptothecin analogue in targeted screening for HIF-1 alpha inhibitors
  2. Klausmeyer, P.; McCloud, T. G.; Melillo, G.; Scudiero, D. A.; Cardellina, J. H.; Shoemaker, R. H.
  3. Planta Medica. 2007, Jan; 73(1): 49-52.
  1. 17.   Hypoxia-inducible factor 1 inhibitors
  2. Melillo, G.
  3. Oxygen Biology and Hypoxia. 2007; 435 : 385-402.
  1. 18.   Crinamine from Crinum asiaticum var.japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2
  2. Kim, Y. H.; Park, E. J.; Park, M. H.; Badarch, U.; Woldemichael, G. M.; Beutler, J. A.
  3. Biological & Pharmaceutical Bulletin. 2006, Oct; 29(10): 2140-2142.
  1. 19.   Inhibiting hypoxia-inducible factor 1 for cancer therapy
  2. Melillo, G.
  3. Molecular Cancer Research. 2006, Sep; 4(9): 601-605.
  1. 20.   Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression
  2. Woldemichael, G. M.; Vasselli, J. R.; Gardella, R. S.; McKee, T. C.; Linehan, W. M.; McMahon, J. B.
  3. Journal of Biomolecular Screening. 2006, Sep; 11(6): 678-687.
  1. 21.   Expression of hypoxia inducible factor-1 alpha and 2 alpha in genetically distinct early renal cortical tumors
  2. Kim, C. M.; Vocke, C.; Torres-Cabala, C.; Yang, Y. F.; Schmidt, L.; Walther, M.; Linehan, W. M.
  3. Journal of Urology. 2006, May; 175(5): 1908-1914.
  1. 22.   Targeting topoisomerases to inhibit hypoxia inducible factor 1 (HIF-1): Mechanism and clinical implications
  2. Melillo, G.
  3. Clinical Cancer Research. 2005, DEC 15; 11(24, Part 2 Suppl. S): 9174S-9175S.
  1. 23.   Topotecan inhibits HIF-1 alpha, but not HIF-2 alpha, protein accumulation and tumor growth in human renal cancer cells
  2. Rapisarda, A.; Uranchimeg, B.; Hollingshead, M.; Borgel, S.; Carter, J.; Shoemaker, R. H.; Melillo, G.
  3. Clinical Cancer Research. 2005, DEC 15; 11(24, Part 2 Suppl. S): 9019S-9019S.
  1. 24.   Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity
  2. Kong, D. H.; Park, E. J.; Stephen, A. G.; Calvani, M.; Cardellina, J. H.; Monks, A.; Fisher, R. J.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2005, OCT 1; 65(19): 9047-9055.
  1. 25.   STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker
  2. Ivanova, A.; Liao, S. Y.; Lerman, M. I.; Ivanov, S.; Stanbridge, E. J.
  3. Journal of Medical Genetics. 2005, JUL; 42(7): 565-576.
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