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  1. 1.   Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas
  2. Lazar, Alexander J.; McLellan, Michael D.; Bailey, Matthew H.; Miller, Christopher A.; Appelbaum, Elizabeth L.; Cordes, Matthew G.; Fronick, Catrina C.; Fulton, Lucinda A.; Fulton, Robert S.; Mardis, Elaine R.; Schmidt, Heather K.; Wong, Winghing; Wilson, Richard K.; Yellapantula, Venkata; Radenbaugh, Amie J.; Hoadley, Katherine A.; Hayes, D. Neil; Parker, Joel S.; Wilkerson, Matthew D.; Auman, J. Todd; Balu, Saianand; Bodenheimer, Tom; Hoyle, Alan P.; Jefferys, Stuart R.; Jones, Corbin D.; Lehmann, Kjong-Van; Meng, Shaowu; Mieczkowski, Piotr A.; Mose, Lisle E.; Perou, Charles M.; Roach, Jeffrey; Senbabaoglu, Yasin; Shi, Yan; Simons, Janae V.; Skelly, Tara; Soloway, Matthew G.; Tan, Donghui; Veluvolu, Umadevi; Davis, Ian J.; Hepperla, Austin J.; Brohl, Andrew S.; Kasaian, Katayoon; Mungall, Karen; Sadeghi, Sara; Barthel, Floris P.; Verhaak, Roel; Hu, Xin; Chibon, Frederic; Cherniack, Andrew D.; Shih, Juliann; Beroukhim, Rameen; Meyerson, Matthew; Cibulskis, Carrie; Gabriel, Stacey B.; Saksena, Gordon; Schumacher, Steven E.; Bailey, Matthew H.; Gao, Qingsong; Wong, Winghing; Wyczalkowski, Matthew; Bowlby, Reanne; Robertson, A. Gordon; Ally, Adrian; Balasundaram, Miruna; Brooks, Denise; Carlsen, Rebecca; Chuah, Eric; Dhalla, Noreen; Holt, Robert A.; Jones, Steven J. M.; Lee, Darlene; Li, Irene; Ma, Yussanne; Marra, Marco A.; Mayo, Michael; Moore, Richard A.; Mungall, Andrew J.; Parker, Joel S.; Schein, Jacqueline E.; Sipahimalani, Payal; Tam, Angela; Thiessen, Nina; Wong, Tina; Danilova, Ludmila; Cope, Leslie; Baylin, Stephen B.; Bootwalla, Moiz S.; Lai, Phillip H.; Laird, Peter W.; Maglinte, Dennis T.; Van Den Berg, David J.; Weisenberger, Daniel J.; Wrangle, John; Drill, Esther; Shen, Ronglai; Iype, Lisa; Reynolds, Sheila M.; Shmulevich, Ilya; Yau, Christina; Armenia, Joshua; Liu, Eric Minwei; Benz, Christopher; Pastore, Alessandro; Sanchez-Vega, Francisco; Schultz, Nikolaus; Akbani, Rehan; Hegde, Apurva M.; Liu, Wenbin; Lu, Yiling; Mills, Gordon B.; Weinstein, John N.; Roszik, Jason; Anur, Pavana; Spellman, Paul; Abeshouse, Adam; Chen, Hsiao-Wei; Gao, Jianjiong; Heins, Zachary; Kundra, Ritika; Larsson, Erik; Ochoa, Angelica; Sanchez-Vega, Francisco; Sander, Chris; Schultz, Nikolaus; Socci, Nicholas; Zhang, Hongxin; Noble, Michael S.; Heiman, David I.; Kim, Jaegil; Chin, Lynda; Getz, Gad; Cho, Juok; Defreitas, Timothy; Frazer, Scott; Gehlenborg, Nils; Lawrence, Michael S.; Lin, Pei; Meier, Sam; Voet, Doug; Zhang, Hailei; Byers, Lauren; Diao, Lixia; Gay, Carl M.; Wang, Jing; Newton, Yulia; Cooper, Lee A. D.; Gutman, David A.; Lazar, Alexander J.; Lee, Sanghoon; Nalisnik, Michael; Bowen, Jay; Gastier-Foster, Julie M.; Gerken, Mark; Helsel, Carmen; Hobensack, Shital; Leraas, Kristen M.; Lichtenberg, Tara M.; Ramirez, Nilsa C.; Wise, Lisa; Zmuda, Erik; Anderson, Matthew L.; Castro, Patricia; Ittmann, Michael; Gordienko, Elena; Paklina, Oxana; Setdikova, Galiya; Raut, Chandrajit P.; Karlan, Beth Y.; Lester, Jenny; Belyaev, Dmitry; Fulidou, Victoria; Potapova, Olga; Voronina, Olga; Demetri, George D.; Ramalingam, Suresh S.; Behera, Madhusmita; Delman, Keith; Owonikoko, Taofeek K.; Sica, Gabriel L.; Boyd, Jeff; Magliocco, Anthony; Salner, Andrew; Bennett, Joesph; Iacocca, Mary; Swanson, Patricia; Dottino, Peter; Kalir, Tamara; Pereira, Elena; Akeredolu, Teniola; Crain, Daniel; Curley, Erin; Gardner, Johanna; Mallery, David; Morris, Scott; Paulauskis, Joseph; Penny, Robert; Shelton, Candace; Shelton, Troy; Thompson, Eric; Hoon, Dave B.; Parfitt, Jeremy; Birrer, Michael; Karseladze, Apollon; Mariamidze, Armaz; Dao, Fanny; Levine, Douglas A.; Olvera, Narciso; Maki, Robert G.; Bartlett, John; Eschbacher, Jennifer; Dubina, Michael; Mozgovoy, Evgeny; Fedosenko, Konstantin; Manikhas, Georgy; Sekhon, Harman; Ramirez, Nilsa; Lazar, Alexander J.; Ingram, Davis R.; Torres, Keila E.; DiSaia, Phil; Godwin, Andrew K.; Godwin, Eryn M.; Kuo, Hanluen; Madan, Rashna; Reilly, Colleen; Adebamowo, Clement; Adebamowo, Sally N.; Bocklage, Therese; Higgins, Kelly; Martinez, Cathleen; Auman, J. Todd; Boice, Lori; Grilley-Olson, Juneko E.; Huang, Mei; Perou, Amy H.; Thorne, Leigh B.; Rathmell, W. Kimryn; Gutmann, David H.; Singer, Samuel; Chudamani, Sudha; Liu, Jia; Lolla, Laxmi; Naresh, Rashi; Pihl, Todd; Sun, Qiang; Wan, Yunhu; Wu, Ye; Felau, Ina; Zenklusen, Jean C.; Demchok, John A.; Ferguson, Martin L.; Hutter, Carolyn M.; Sofia, Heidi J.; Tarnuzzer, Roy; Wang, Zhining; Yang, Liming; Zhang, Jiashan (Julia); Demicco, Elizabeth G.; Doyle, Leona A.; Hornick, Jason L.; Lazar, Alexander J.; Rubin, Brian P.; de Rijn, Matt van; Demetri, George D.; Baker, Laurence; Grilley-Olson, Juneko E.; Iype, Lisa; Lazar, Alexander J.; Lichtenberg, Tara M.; Raut, Chandrajit P.; Riedel, Richard F.; Demicco, Elizabeth G.; Ding, Li; Ladanyi, Marc; Lazar, Alexander J.; Novak, Janet E.; Sanchez-Vega, Francisco; Singer, Samuel; Van Tine, Brian A.; Byers, Lauren; Cope, Leslie; Cherniack, Andrew D.; Cooper, Lee A. D.; Davis, Ian J.; Davis, Lara E.; Demetri, George D.; Doyle, Leona A.; Drill, Esther; Godwin, Andrew K.; Grilley-Olsen, Juneko E.; Gutmann, David H.; Hayes, D. Neil; Hepperla, Austin J.; Hoadley, Katherine A.; Hoon, Dave B.; Hornick, Jason L.; Iype, Lisa; Kim, Jaegil; Maki, Robert G.; Pollock, Raphael E.; Raut, Chandrajit P.; Riedel, Richard F.; Robertson, A. Gordon; Rubin, Brian P.; Shih, Juliann; Weinstein, John N.; Wong, Winghing; Akbani, Rehan; Anderson, Matthew L.; Anur, Pavana; Bailey, Matthew H.; Benz, Christopher; Bowen, Jay; Bowlby, Reanne; Brohl, Andrew S.; Cherniack, Andrew D.; Cooper, Lee A. D.; Cope, Leslie; Danilova, Ludmila; Davis, Lara E.; Demetri, George D.; Gay, Carl M.; Godwin, Andrew K.; Grilley-Olson, Juneko E.; Gutman, David A.; Hegde, Apurva M.; Jones, Kevin B.; Kasaian, Katayoon; Ladanyi, Marc; Lazar, Alexander J.; Lee, Sanghoon; Leraas, Kristen M.; Lichtenberg, Tara M.; Martignetti, John A.; McLellan, Michael D.; Miller, Christopher A.; Mungall, Karen; Nalisnik, Michael; Noble, Michael S.; Raut, Chandrajit P.; Riedel, Richard F.; Robertson, A. Gordon; Roszik, Jason; Sadeghi, Sara; Sanchez-Vega, Francisco; Shen, Ronglai; Shih, Juliann; Tong, Pan; Torres, Keila E.; Yau, Christina; Zenklusen, Jean C.
  3. Cell. 2017, Nov 02; 171(4): 950-965.
  1. 2.   Antitumor Activity of a Novel Oncrasin Analogue Is Mediated by JNK Activation and STAT3 Inhibition
  2. Guo, W.; Wu, S. H.; Wang, L.; Wei, X. L.; Liu, X. Y.; Wang, J.; Lu, Z. M.; Hollingshead, M.; Fang, B. L.
  3. Plos One. 2011, Dec; 6(12):
  1. 3.   Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
  2. Gui, Y. T.; Guo, G. W.; Huang, Y.; Hu, X. D.; Tang, A. F.; Gao, S. J.; Wu, R. H.; Chen, C.; Li, X. X.; Zhou, L.; He, M. H.; Li, Z. S.; Sun, X. J.; Jia, W. L.; Chen, J. N.; Yang, S. M.; Zhou, F. J.; Zhao, X. K.; Wan, S. Q.; Ye, R.; Liang, C. Z.; Liu, Z. S.; Huang, P. D.; Liu, C. X.; Jiang, H.; Wang, Y.; Zheng, H. C.; Sun, L.; Liu, X. W.; Jiang, Z. M.; Feng, D. F.; Chen, J.; Wu, S.; Zou, J.; Zhang, Z. F.; Yang, R. L.; Zhao, J.; Xu, C. J.; Yin, W. H.; Guan, Z. C.; Ye, J. X.; Zhang, H.; Li, J. X.; Kristiansen, K.; Nickerson, M. L.; Theodorescu, D.; Li, Y. R.; Zhang, X. Q.; Li, S. G.; Wang, J.; Yang, H. M.; Cai, Z. M.
  3. Nature Genetics. 2011, Sep; 43(9): 875-U84.
  1. 4.   Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras(G12D) from the endogenous locus
  2. Li, Q.; Haigis, K. M.; McDaniel, A.; Harding-Theobald, E.; Kogan, S. C.; Akagi, K.; Wong, J. C. Y.; Braun, B. S.; Wolff, L.; Jacks, T.; Shannon, K.
  3. Blood. 2011, Feb; 117(6): 2022-2032.
  1. 5.   Bortezomib Sensitizes Human Esophageal Squamous Cell Carcinoma Cells to TRAIL-Mediated Apoptosis via Activation of Both Extrinsic and Intrinsic Apoptosis Pathways
  2. Seki, N.; Toh, U.; Sayers, T. J.; Fujii, T.; Miyagi, M.; Akagi, Y.; Kusukawa, J.; Kage, M.; Shirouzu, K.; Yamana, H.
  3. Molecular Cancer Therapeutics. 2010, Jun; 9(6): 1842-1851.
  1. 6.   The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis
  2. Menigatti, M.; Cattaneo, E.; Sabates-Bellver, J.; Ilinsky, V. V.; Went, P.; Buffoli, F.; Marquez, V. E.; Jiricny, J.; Marra, G.
  3. Molecular Cancer. 2009, Dec; 8: 11.
  1. 7.   Autoimmunity, spontaneous tumourigenesis, and IL-15 insufficiency in mice with a targeted disruption of the tumour suppressor gene FusI
  2. Ivanova, A. V.; Ivanov, S. V.; Pascal, V.; Lumsden, J. M.; Ward, J. M.; Morris, N.; Tessarolo, L.; Anderson, S. K.; Lerman, M. I.
  3. Journal of Pathology. 2007, Apr; 211(5): 591-601.
  1. 8.   Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
  2. Rudelius, M.; Pittaluga, S.; Nishizuka, S.; Pham, T. H. T.; Fend, F.; Jaffe, E. S.; Quintanilla-Martinez, L.; Raffeld, M.
  3. Blood. 2006, Sep; 108(5): 1668-1676.
  1. 9.   Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator
  2. Hurt, E. M.; Thomas, S. B.; Peng, B.; Farrar, W. L.
  3. Cancer Biology & Therapy. 2006, Sep; 5(9): 1154-1160.
  1. 10.   Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis
  2. Hong, S. B.; Furihata, M.; Baba, M.; Zbar, B.; Schmidt, L. S.
  3. Laboratory Investigation. 2006, Jul; 86(7): 664-675.
  1. 11.   Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells
  2. de la Pena, L.; Burgan, W. E.; Carter, D. J.; Hollingshead, M. G.; Satyamitra, M.; Camphausen, K.; Tofilon, P. J.
  3. Molecular Cancer Therapeutics. 2006, Jun; 5(6): 1504-1510.
  1. 12.   Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis
  2. Zudaire, E.; Martinez, A.; Garayoa, M.; Pio, R.; Kaur, G.; Woolhiser, M. R.; Metcalfe, D. D.; Hook, W. A.; Siraganian, R. P.; Guise, T. A.; Chirgwin, J. M.; Cuttitta, F.
  3. American Journal of Pathology. 2006, JAN; 168(1): 280-291.
  1. 13.   Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer
  2. Kanao, H.; Enomoto, T.; Kimura, T.; Fujita, M.; Nakashima, R.; Ueda, Y.; Ueno, Y.; Miyatake, T.; Yoshizaki, T.; Buzard, G. S.; Tanigami, A.; Yoshino, K.; Murata, Y.
  3. Cancer Research. 2005, OCT 1; 65(19): 8640-8645.
  1. 14.   Retinoic acid-induced downmodulation of telomerase activity in human cancer cells
  2. Xiao, X. D.; Sidorov, I. A.; Gee, J.; Lempicki, R. A.; Dimitrov, D. S.
  3. Experimental and Molecular Pathology. 2005, OCT; 79(2): 108-117.
  1. 15.   Structure-based discovery of a boronic acid bioisostere of combretastatin A-4
  2. Kong, Y.; Grembecka, J.; Edler, M. C.; Hamel, E.; Mooberry, S. L.; Sabat, M.; Rieger, J.; Brown, M. L.
  3. Chemistry & Biology. 2005, SEP; 12(9): 1007-1014.
  1. 16.   Cancer biology and hormesis: Comments on Calabrese (2005)
  2. Anderson, L. M.
  3. Critical Reviews in Toxicology. 2005, JUL; 35(6): 583-586.
  1. 17.   Dolastatin 11 conformations, analogues and pharmacophore
  2. Ali, M. A.; Bates, R. B.; Crane, Z. D.; Dicus, C. W.; Gramme, M. R.; Hamel, E.; Marcischak, J.; Martinez, D. S.; McClure, K. J.; Nakkiew, P.; Pettit, G. R.; Stessman, C. C.; Sufi, B. A.; Yarick, G. V.
  3. Bioorganic & Medicinal Chemistry. 2005, JUL 1; 13(13): 4138-4152.
  1. 18.   Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-4
  2. Pettit, G. R.; Rhodes, M. R.; Herald, D. L.; Hamel, E.; Schmidt, J. M.; Pettitt, R. K.
  3. Journal of Medicinal Chemistry. 2005, JUN 16; 48(12): 4087-4099.
  1. 19.   Ascorbate depletion: A critical step in nickel carcinogenesis?
  2. Salnikow, K.; Kasprzak, K. S.
  3. Environmental Health Perspectives. 2005, MAY; 113(5): 577-584.
  1. 20.   In the quest for stable rescuing mutants of p53: Computational mutagenesis of flexible loop L1
  2. Pan, Y. P.; Ma, B. Y.; Venkataraghavan, R. B.; Levine, A. J.; Nussinov, R.
  3. Biochemistry. 2005, FEB 8; 44(5): 1423-1432.
  1. 21.   Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics
  2. Sun, H. Y.; Nikolovska-Coleska, Z.; Chen, J. Y.; Yang, C. Y.; Tomita, Y.; Pan, H. G.; Yoshioka, Y.; Krajewski, K.; Roller, P. P.; Wang, S. M.
  3. Bioorganic & Medicinal Chemistry Letters. 2005, FEB 1; 15(3): 793-797.
  1. 22.   Human autologous tumor-specific T-cell responses induced by liposomal delivery of a lymphoma antigen
  2. Neelapu, S. S.; Baskar, S.; Gause, B. L.; Kobrin, C. B.; Watson, T. M.; Frye, A. R.; Pennington, R.; Harvey, L.; Jaffe, E. S.; Robb, R. J.; Popescu, M. C.; Kwak, L. W.
  3. Clinical Cancer Research. 2004, DEC 15; 10(24): 8309-8317.
  1. 23.   Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
  2. Graveel, C.; Su, Y. L.; Koeman, J.; Wang, L. M.; Tessarollo, L.; Fiscella, M.; Birchmeier, C.; Swiatek, P.; Bronson, R.; Woude, G. V.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2004, DEC 7; 101(49): 17198-17203.
  1. 24.   Fluorinated 2-(4-amino-3-methylphenyl) benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells
  2. Brantley, E.; Trapani, V.; Alley, M. C.; Hose, C. D.; Bradshaw, T. D.; Stevens, M. F. G.; Sausville, E. A.; Stinson, S. F.
  3. Drug Metabolism and Disposition. 2004, DEC; 32(12): 1392-1401.
  1. 25.   Cellular 8-oxo-7,8-dihydro-2 '-deoxyguanosine 5 '-triphosphate pyrophosphohydrolase activity of human and mouse MTH1 proteins does not depend on the proliferation rate
  2. Bialkowski, K.; Kasprzak, K. S.
  3. Free Radical Biology and Medicine. 2004, NOV 15; 37(10): 1534-1541.
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