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  1. 1.   Systemic inflammatory Th1 cytokines during Trypanosoma cruzi infection disrupt the typical anatomical cell distribution and phenotypic/functional characteristics of various cell subsets within the thymus
  2. Viano, Estefania; Baez, Natalia S; Savid-Frontera, Constanza; Baigorrí, Eliana; Dinatale, Brenda; Pacini, Maria Florencia; Bulfoni Balbi, Camila; Gonzalez, Florencia Belén; Fozzatti, Laura; Lidón, Nicolas L; Young,Howard; Hodge, Deborah; Cerban, Fabio; Stempin, Cinthia; Pérez, Ana Rosa; Rodriguez Galán, Maria Cecilia
  3. Microbes and Infection. 2024, Apr 12; 105337.
  1. 2.   Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
  2. Harrison, Oliver J.; Linehan, Jonathan L.; Shih, Han-Yu; Bouladoux, Nicolas; Han, Seong-Ji; Smelkinson, Margery; Sen, Shurjo; Byrd, Allyson L.; Enamorado, Michel; Yao, Chen; Tamoutounour, Samira; Van Laethem, Francois; Hurabielle, Charlotte; Collins, Nicholas; Paun, Andrea; Salcedo, Rosalba; O'Shea, John J.; Belkaid, Yasmine
  3. Science (New York, N.Y.). 2019, Jan 4; 363(6422): 43-+.
  1. 3.   Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance
  2. An, P.; Thio, C. L.; Kirk, G. D.; Donfield, S.; Goedert, J. J.; Winkler, C. A.
  3. Journal of Infectious Diseases. 2008 198(8): 1159-1165.
  1. 4.   Cytokines in pulmonary emphysema: Can results in mice be translated to humans?
  2. Hoshino, T.; Young, H. A.; Aizawa, H.
  3. American Journal of Respiratory and Critical Care Medicine. 2008 177(2): 238-239.
  1. 5.   Pulmonary inflammation and emphysema - Role of the Cytokines IL-18 and IL-13
  2. Hoshino, T.; Kato, S.; Oka, N.; Imaoka, H.; Kinoshita, T.; Takei, S.; Kitasato, Y.; Kawayama, T.; Imaizumi, T.; Yamada, K.; Young, H. A.; Aizawa, H.
  3. American Journal of Respiratory and Critical Care Medicine. 2007, Jul; 176(1): 49-62.
  1. 6.   Regulation of ITAM-positive receptors: role of IL-12 and IL-18
  2. Ortaldo, J. R.; Winkler-Pickett, R.; Wigginton, J.; Horner, M.; Bere, E. W.; Mason, A. T.; Bhat, N.; Cherry, J.; Sanford, M.; Hodge, D. L.; Young, H. A.
  3. Blood. 2006, FEB 15; 107(4): 1468-1475.
  1. 7.   Cytokines as critical co-stimulatory molecules in modulating the immune response of natural killer cells
  2. Young, H. A.; Ortaldo, J.
  3. Cell Research. 2006, Jan; 16(1): 20-24.
  1. 8.   Toxicity vs antitumor effects of hydrodynamic IL-12 (interleukin-12) and IL-18 cDNA injections
  2. Rodriguez-Galan, M. C.; Watanabe, M.; Young, H. A.
  3. Faseb Journal. 2005, MAR 7; 19(5, Part 2, Suppl. S): A1406-A1406.
  1. 9.   Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression
  2. Rodriguez-Galan, M. C.; Bream, J. H.; Farr, A.; Young, H. A.
  3. Journal of Immunology. 2005, MAR 1; 174(5): 2796-2804.
  1. 10.   Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization
  2. Mohamadzadeh, M.; Olson, S.; Kalina, W. V.; Ruthel, G.; Demmin, G. L.; Warfield, K. L.; Bavari, S.; Klaenhammer, T. R.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 22; 102(8): 2880-2885.
  1. 11.   Tumor cell IFN-gamma responsiveness mediates the generation of tumor-specific immunologic reactivity and overall antitumor activity of IL-18 in mice bearing neuroblastoma tumors
  2. Hixon, J.; Stauffer, J. K.; Khan, T.; Salcedo, R.; Lincoln, E.; Back, T. C.; Jonak, Z.; Dar, M.; Wigginton, J. M.
  3. Journal of Immunotherapy. 2005, NOV-DEC; 28(6): 627-627.
  1. 12.   IL-18 plus IL-12 decreases liver metastases through An NK cell, IFN-gamma dependent mechanism and overcomes NK/T cell mediated suppression
  2. Subleski, A.; Back, T. C.; Ortaldo, J. R.; Wiltrout, R. H.
  3. Journal of Immunotherapy. 2005, NOV-DEC; 28(6): 626-626.
  1. 13.   NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer
  2. Smyth, M. J.; Swann, J.; Kelly, J. M.; Cretney, E.; Yokoyama, W. M.; Diefenbach, A.; Sayers, T. J.; Hayakawa, Y.
  3. Journal of Experimental Medicine. 2004, NOV 15; 200(10): 1325-1335.
  1. 14.   IL-18 induces complete regression of orthotopic primary and metastatic murine neuroblastoma tumors and potentiates antitumor immune reactivity in combination with IL-2
  2. Hixon, J.; Stauffer, J.; Lincoln, E.; Back, T.; Jonak, Z.; Wigginton, J.
  3. Journal of Immunotherapy. 2004, NOV-DEC; 27(6): S17-S18.
  1. 15.   Toxicity vs. antitumor activity of IL-12 and IL-18 cDNA injections in C57BL/6 mice
  2. Rodriguez-Galan, M. C.; Watanabe, M.; Young, H. A.
  3. Journal of Leukocyte Biology. 2004 (Suppl. S): 56-56.
  1. 16.   Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury
  2. Hoshino, T.; Nakamura, H.; Okamoto, M.; Kato, S.; Araya, S.; Nomiyama, K.; Oizumi, K.; Young, H. A.; Aizawa, H.; Yodoi, J.
  3. American Journal of Respiratory and Critical Care Medicine. 2003 168(9): 1075-1083.
  1. 17.   Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand- dependent tumor eradication by combined administration of IL-18 and IL-2
  2. Wigginton, J. M.; Lee, J. K.; Wiltrout, T. A.; Alvord, W. G.; Hixon, J. A.; Subleski, J.; Back, T. C.; Wiltrout, R. H.
  3. Journal of Immunology. 2002 169(8): 4467-4474.
  1. 18.   In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4(+) T cells
  2. Hoshino, T.; Yagita, H.; Ortaldo, J. R.; Wiltrout, R. H.; Young, H. A.
  3. European Journal of Immunology. 2000 30(7): 1998-2006.
  1. 19.   Exploring the immunomodulatory role of virtual memory CD8+ T cells: Role of IFN gamma in tumor growth control
  2. Savid-Frontera, Constanza; Viano, Maria Estefania; Baez, Natalia S; Lidon, Nicolas L; Fontaine, Quentin; Young,Howard; Vimeux, Lene; Donnadieu, Emmanuel; Rodriguez-Galan, Maria Cecilia
  3. Frontiers in Immunology. 2022 13: 971001.
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