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  1. 1.   Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors
  2. Ng,Martin; Wang, Huanchen; Zhang, Haibo; Prucker, Isabel; Perera, Lalith; Goncharova,Katya; Wamiru,Antony; Jessen, Henning J; Stanley, Robin E; Shears, Stephen B; Luo, Ji; O'Keefe,Barry; Wilson,Brice
  3. The Journal of Biological Chemistry. 2025, Feb 06; 108274.
  1. 2.   Improved Production of Class I Phosphatidylinositol 4,5-bisphosphate 3-kinase
  2. Messing,Simon; Widmeyer, Stephanie R T; Denson,John-Paul; Mehalko,Jennifer; Wall,Vanessa; Drew,Matt; Snead,Kelly; Hong,Min; Grose,Carissa; Esposito,Dom; Gillette,Bill
  3. Protein Expression and Purification. 2024, Aug 20; 106582.
  1. 3.   Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication
  2. Biswas, Banhi; Lai,Kin Kui; Bracey, Harrison; Datta,Siddhartha; Harvin, Demetria; Sowd, Gregory A; Aiken, Christopher; Rein,Alan
  3. mBio. 2024, Jul 17; 15(7): e0115824.
  1. 4.   The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice
  2. Kleinpeter,Alex; Zhu, Yanan; Mallery, Donna L; Ablan,Sherimay; Chen, Long; Hardenbrook, Nathan; Saiardi, Adolfo; James, Leo C; Zhang, Peijun; Freed,Eric
  3. Journal of Molecular Biology. 2023, Apr 01; 435(11): 168037.
  1. 5.   A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection
  2. Kroon, Eugene D. M. D.; Ananworanich, Jintanat; Pagliuzza, Amelie; Rhodes, Ajantha; Phanuphak, Nittaya; Trautmann, Lydie; Mitchell, Julie L.; Chintanaphol, Michelle; Intasan, Jintana; Pinyakorn, Suteeraporn; Benjapornpong, Khuntalee; Chang, J. Judy; Colby, Donn J.; Chomchey, Nitiya; Fletcher, James L. K.; Eubanks, Keith; Yang, Hua; Kapson, John; Dantanarayana, Ashanti; Tennakoon, Surekha; Gorelick,Robert; Maldarelli, Frank; Robb, Merlin L.; Kim, Jerome H.; Spudich, Serena; Chomont, Nicolas; Phanuphak, Praphan; Lewin, Sharon R.; de Souza, Mark S.
  3. JOURNAL OF VIRUS ERADICATION. 2020, SEP; 6(3): 100004.
  1. 6.   Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication
  2. Mallery, Donna L; Faysal, K M Rifat; Kleinpeter,Alex; Wilson, Miranda S C; Vaysburd, Marina; Fletcher, Adam J; Novikova, Mariia; Böcking, Till; Freed,Eric; Saiardi, Adolfo; James, Leo C
  3. Cell reports. 2019, Dec 17; 29(12): 3983-3996.e4.
  1. 7.   Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate
  2. Roy, Neeladri Sekhar; Jian, Xiaoying; Soubias,Olivier; Zhai, Peng; Hall, Jessica R.; Dagher, Jessica N.; Coussens, Nathan P.; Jenkins, Lisa M.; Luo, Ruibai; Akpan, Itoro O.; Hall, Matthew D.; Byrd,Robert; Yohe, Marielle E.; Randazzo, Paul A.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, NOV 15; 294(46): 17354-17370.
  1. 8.   The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin
  2. Jang,Hyunbum; Banerjee, Avik; Marcus, Kendra; Makowski, Lee; Mattos, Carla; Gaponenko, Vadim; Nussinov,Ruth
  3. Structure (London, England : 1993). 2019, Nov 5; 27(11): 1647-1659.e4.
  1. 9.   Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
  2. Khil, Pavel P; Dulanto Chiang, Augusto; Ho, Jonathan; Youn, Jung-Ho; Lemon, Jamie K; Gea-Banacloche, Juan; Frank, Karen M; Parta,Mark; Bonomo, Robert A; Dekker, John P
  3. mBio. 2019, Sep; 10(5): pii: e01822-19.
  1. 10.   An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos
  2. Gignoux, Chris R; Torgerson, Dara G; Pino-Yanes, Maria; Uricchio, Lawrence H; Galanter, Joshua; Roth, Lindsey A; Eng, Celeste; Hu, Donglei; Nguyen, Elizabeth A; Huntsman, Scott; Mathias, Rasika A; Kumar, Rajesh; Rodriguez-Santana, Jose; Thakur, Neeta; Oh, Sam S; McGarry, Meghan; Moreno-Estrada, Andres; Sandoval, Karla; Winkler, Cheryl; Seibold, Max A; Padhukasahasram, Badri; Conti, David V; Farber, Harold J; Avila, Pedro; Brigino-Buenaventura, Emerita; Lenoir, Michael; Meade, Kelley; Serebrisky, Denise; Borrell, Luisa N; Rodriguez-Cintron, William; Thyne, Shannon; Joubert, Bonnie R; Romieu, Isabelle; Levin, Albert M; Sienra-Monge, Juan-Jose; Del Rio-Navarro, Blanca Estela; Gan, Weiniu; Raby, Benjamin A; Weiss, Scott T; Bleecker, Eugene; Meyers, Deborah A; Martinez, Fernando J; Gauderman, W James; Gilliland, Frank; London, Stephanie J; Bustamante, Carlos D; Nicolae, Dan L; Ober, Carole; Sen, Saunak; Barnes, Kathleen; Williams, L Keoki; Hernandez, Ryan D; Burchard, Esteban G
  3. Journal of Allergy and Clinical Immunology. 2019, Mar; 143(3): 957-969.
  1. 11.   Calmodulin (CaM) Activates PI3K alpha by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha
  2. Zhang,Mingzhen; Li, Zhigang; Wang, Guanqiao; Jang,Hyunbum; Sacks, David B.; Zhang, Jian; Gaponenko, Vadim; Nussinov,Ruth
  3. JOURNAL OF PHYSICAL CHEMISTRY B. 2018, Dec 13; 122(49): 11137-11146.
  1. 12.   Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma
  2. Mak, Angel Cy; White, Marquitta J; Eckalbar, Walter L; Szpiech, Zachary A; Oh, Sam S; Pino-Yanes, Maria; Hu, Donglei; Goddard, Pagé; Huntsman, Scott; Galanter, Joshua; Wu, Ann Chen; Himes, Blanca E; Germer, Soren; Vogel, Julia M; Bunting, Karen L; Eng, Celeste; Salazar, Sandra; Keys, Kevin L; Liberto, Jennifer; Nuckton, Thomas J; Nguyen, Thomas A; Torgerson, Dara G; Kwok, Pui-Yan; Levin, Albert M; Celedón, Juan C; Forno, Erick; Hakonarson, Hakon; Sleiman, Patrick M; Dahlin, Amber; Tantisira, Kelan G; Weiss, Scott T; Serebrisky, Denise; Brigino-Buenaventura, Emerita; Farber, Harold J; Meade, Kelley; Lenoir, Michael A; Avila, Pedro C; Sen, Saunak; Thyne, Shannon M; Rodriguez-Cintron, William; Winkler, Cheryl; Moreno-Estrada, Andrés; Sandoval, Karla; Rodriguez-Santana, Jose R; Kumar, Rajesh; Williams, L Keoki; Ahituv, Nadav; Ziv, Elad; Seibold, Max A; Darnell, Robert B; Zaitlen, Noah; Hernandez, Ryan D; Burchard, Esteban G
  3. American Journal of Respiratory and Critical Care Medicine. 2018, Jun 15; 197(12): 1552-1564.
  1. 13.   Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit
  2. Wang, Guanqiao; Zhang, Mingzhen; Jang, Hyunbum; Lu, Shaoyong; Lin, Shizhou; Chen, Guoqiang; Nussinov, Ruth; Zhang, Jian; Gaponenko, Vadim
  3. Biochemistry. 2018, Mar 27; 57(12): 1917-1928.
  1. 14.   Antimicrobial Activity of Ibuprofen against Cystic Fibrosis-Associated Gram-Negative Pathogens
  2. Shah, Parth N.; Marshall-Batty, Kimberly R.; Smolen, Justin A.; Tagaev, Jasur A.; Chen, Qingquan; Rodesney, Christopher A.; Le, Henry H.; Gordon, Vernita D.; Greenberg, David E.; Cannon, Carolyn L.
  3. Antimicrobial Agents and Chemotherapy. 2018, Mar; 62(3): e01574-17.
  1. 15.   Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers
  2. Howard, James J.; Sturge, Carolyn R.; Moustafa, Dina A.; Daly, Seth M.; Batty, Kimberly; Felder, Christina F.; Zamora, Danniel; Yabe-Gill, Marium; Labandeira-Rey, Maria; Bailey, Stacey M.; Wong, Michael; Goldberg, Joanna B.; Geller, Bruce L.; Greenberg, David E.
  3. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2017, Apr; 61(4):
  1. 16.   Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection
  2. Sektioglu, I. M.; Carretero, R.; Bender, N.; Bogdan, C.; Garbi, N.; Umansky, V.; Umansky, L.; Urban, K.; von Knebel-Doberitz, M.; Somasundaram, V.; Wink, D.; Beckhove, P.; Hammerling, G. J.
  3. Oncoimmunology. 2016 5(10): e1204506.
  1. 17.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 18.   Modifications of Glycans: Biological Significance and Therapeutic Opportunities
  2. Muthana, S. M.; Campbell, C. T.; Gildersleeve, J. C.
  3. Acs Chemical Biology. 2012, Jan; 7(1): 31-43.
  1. 19.   Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy
  2. Sasaki, D.; Imaizumi, Y.; Hasegawa, H.; Osaka, A.; Tsukasaki, K.; Choi, Y. L.; Mano, H.; Marquez, V. E.; Hayashi, T.; Yanagihara, K.; Moriwaki, Y.; Miyazaki, Y.; Kamihira, S.; Yamada, Y.
  3. Haematologica-the Hematology Journal. 2011, May; 96(5): 712-719.
  1. 20.   Association of Src-Related Kinase Lyn with the Interleukin-2 Receptor and Its Role in Maintaining Constitutive Phosphorylation of JAK/STAT in Human T-Cell Leukemia Virus Type 1-Transformed T Cells
  2. Shuh, M. S. M.; Morse, B. A.; Heidecker, G.; Derse, D.
  3. Journal of Virology. 2011, May; 85(9): 4623-4627.
  1. 21.   TLR-based immune adjuvants
  2. Steinhagen, F.; Kinjo, T.; Bode, C.; Klinman, D. M.
  3. Vaccine. 2011, Apr; 29(17): 3341-3355.
  1. 22.   Clarification of the Mechanism of Acylation Reaction and Origin of Substrate Specificity of the Serine-Carboxyl Peptidase Sedolisin through QM/MM Free Energy Simulations
  2. Xu, Q.; Yao, J. Z.; Wlodawer, A.; Guo, H.
  3. Journal of Physical Chemistry B. 2011, Mar; 115(10): 2470-2476.
  1. 23.   Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes
  2. Franquelim, H. G.; Chiantia, S.; Veiga, A. S.; Santos, N. C.; Schwille, P.; Castanho, M.
  3. Aids. 2011, Feb; 25(4): 419-428.
  1. 24.   Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay
  2. Best, A. M.; Chang, J. J.; Dull, A. B.; Beutler, J. A.; Martinez, E. D.
  3. Journal of Biomedicine and Biotechnology. 2011 11.
  1. 25.   Protein expression profiles distinguish between experimental invasive pulmonary aspergillosis and Pseudomonas pneumonia
  2. Gonzales, D. A.; De Torre, C.; Wang, H. H.; Devor, C. B.; Munson, P. J.; Ying, S. X.; Kern, S. J.; Petraitiene, R.; Levens, D. L.; Walsh, T. J.; Suffredini, A. F.
  3. Proteomics. 2010, Dec; 10(23): 4270-4280.
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