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  1. 1.   A fully human anti-IL-7Ra antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
  2. Akkapeddi, Padma; Fragoso, Rita; Hixon, Julie; Ramalho, Ana Sofia; Oliveira, Mariana L; Carvalho, Tânia; Gloger, Andreas; Matasci, Mattia; Corzana, Francisco; Durum, Scott; Neri, Dario; Bernardes, Gonçalo J L; Barata, João T
  3. Leukemia. 2019, SEP; 33(9): 2155-2168.
  1. 2.   Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
  2. Zenatti, P. P.; Ribeiro, D.; Li, W. Q.; Zuurbier, L.; Silva, M. C.; Paganin, M.; Tritapoe, J.; Hixon, J. A.; Silveira, A. B.; Cardoso, B. A.; Sarmento, L. M.; Correia, N.; Toribio, M. L.; Kobarg, J.; Horstmann, M.; Pieters, R.; Brandalise, S. R.; Ferrando, A. A.; Meijerink, J. P.; Durum, S. K.; Yunes, J. A.; Barata, J. T.
  3. Nature Genetics. 2011, Oct; 43(10): 932-U31.
  1. 3.   Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance
  2. Hodge, J. N.; Srinivasula, S.; Hu, Z. H.; Read, S. W.; Porter, B. O.; Kim, I.; Mican, J. M.; Paik, C.; DeGrange, P.; Di Mascio, M.; Sereti, I.
  3. Blood. 2011, Sep; 118(12): 3244-3253.
  1. 4.   Increased CD4(+) T Cell Levels during IL-7 Administration of Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Positive Macaques Are Not Dependent on Strong Proliferative Responses
  2. Leone, A.; Rohankhedkar, M.; Okoye, A.; Legasse, A.; Axthelm, M. K.; Villinger, F.; Piatak, M.; Lifson, J. D.; Assouline, B.; Morre, M.; Picker, L. J.; Sodora, D. L.
  3. Journal of Immunology. 2010, Aug; 185(3): 1650-1659.
  1. 5.   Immunologic and Virologic Events in Early HIV Infection Predict Subsequent Rate of Progression
  2. Ganesan, A.; Chattopadhyay, P. K.; Brodie, T. M.; Qin, J.; Gu, W. J.; Mascola, J. R.; Michael, N. L.; Follmann, D. A.; Roederer, M.; Infect Dis Clinical Res Program, H. I.
  3. Journal of Infectious Diseases. 2010, Jan; 201(2): 272-284.
  1. 6.   Development of regulatory T cells requires IL-7R alpha stimulation by IL-7 or TSLP
  2. Mazzucchelli, R.; Hixon, J. A.; Spolski, R.; Chen, X.; Li, W. Q.; Hall, V. L.; Willette-Brown, J.; Hurwitz, A. A.; Leonard, W. J.; Durum, S. K.
  3. Blood. 2008, Oct 15; 112(8): 3283-3292.
  1. 7.   Role of the intracellular domain of IL-7 receptor in T cell development
  2. Jiang, Q.; Huang, J.; Li, W. Q.; Cavinato, T.; Keller, J. R.; Durum, S. K.
  3. Journal of Immunology. 2007, Jan; 178(1): 228-234.
  1. 8.   Stat5a/b are essential for normal lymphoid development and differentiation
  2. Yao, Z. J.; Cui, Y. Z.; Watford, W. T.; Bream, J. H.; Yamaoka, K.; Hissong, B. D.; Li, D.; Durum, S. K.; Jiang, Q. O.; Bhandoola, A.; Hennighausen, L.; O'Shea, J. J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 24; 103(4): 1000-1005.
  1. 9.   Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
  2. Yu, Q.; Park, J. H.; Doan, L. L.; Erman, B.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2006, JAN 23; 203(1): 165-175.
  1. 10.   IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and ROR gamma t: Impact on thymocyte development
  2. Yu, Q.; Erman, B.; Park, J. H.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2004, SEP 20; 200(6): 797-803.
  1. 11.   IL-7 induces tyrosine phosphorylation of clathrin heavy chain
  2. Jiang, Q.; Benbernou, N.; Chertov, O.; Khaled, A. R.; Wooters, J.; Durum, S. K.
  3. Cellular Signalling. 2004 16(2): 281-286.
  1. 12.   Epigenetic control during lymphoid development and immune responses - Aberrant regulation, viruses, and cancer
  2. Muegge, K.; Young, H.; Ruscetti, F.; Mikovits, J.
  3. Epigenetics in Cancer Prevention: Early Detection and Risk Assessment. 2003; 983 : 55-70.
  1. 13.   Restricting Zap70 expression to CD4(+)CD8(+) thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection
  2. Liu, X. L.; Adams, A.; Wildt, K. F.; Aronow, B.; Feigenbaum, L.; Bosselut, R.
  3. Journal of Experimental Medicine. 2003 197(3): 363-373.
  1. 14.   Lymphocide: Cytokines and the control of lymphoid homeostasis
  2. Khaled, A. R.; Durum, S. K.
  3. Nature Reviews Immunology. 2002 2(11): 817-830.
  1. 15.   Defective T-Cell Receptor Gamma Gene Rearrangement in Interleukin-7 Receptor Knockout Mice
  2. Candeias, S.; Peschon, J. J.; Muegge, K.; Durum, S. K.
  3. Immunology Letters. 1997 57(1-3): 9-14.
  1. 16.   Il-7 Activates Alpha(4)Beta(1) Integrin in Murine Thymocytes
  2. Kitazawa, H.; Muegge, K.; Badolato, R.; Wang, J. M.; Fogler, W. E.; Ferris, D. K.; Lee, C. K.; Candeias, S.; Smith, M. R.; Oppenheim, J. J.; Durum, S. K.
  3. Journal of Immunology. 1997 159(5): 2259-2264.
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