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  1. 1.   Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids
  2. Coussens,Nathan; Dexheimer,Thomas; Silvers,Thomas; Sanchez,Phillip; Chen,Li; Hollingshead, Melinda G; Takebe, Naoko; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2025, Apr 08; 100230.
  1. 2.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 3.   Allosteric modulation of NF1 GAP: Differential distributions of catalytically competent populations in loss-of-function and gain-of-function mutants
  2. Xu,Liang; Jang,Hyunbum; Nussinov,Ruth
  3. Protein Science : a publication of the Protein Society. 2025, Feb; 34(2): e70042.
  1. 4.   Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
  2. Smith,Steven; Zhao,Xuezhi; Hughes,Stephen; Burke,Terrence
  3. Viruses. 2025, Jan 16; 17(1):
  1. 5.   Inferring phase transitions and critical exponents from limited observations with thermodynamic maps
  2. Herron, Lukas; Mondal, Kinjal; Schneekloth,Jay; Tiwary, Pratyush
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Dec 24; 121(52): e2321971121.
  1. 6.   Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
  2. Temme,Joel; Tan, Zibin; Li,Mi; Yang,Mo; Wlodawer,Alexander; Huang, Xuefei; Schneekloth,Jay; Gildersleeve,Jeffrey
  3. Cell Chemical Biology. 2024, Dec 02;
  1. 7.   Affinity Tag-Free Purification of SARS-CoV-2 N Protein and Its Crystal Structure in Complex with ssDNA
  2. Maiti,Atanu; Matsuo,Hiroshi
  3. Biomolecules. 2024, Nov 30; 14(12):
  1. 8.   Genomic insights for personalised care in lung cancer and smoking cessation: motivating at-risk individuals toward evidence-based health practices
  2. Chen, Tony; Pham, Giang; Fox, Louis; Adler, Nina; Wang,Kevin; Zhang, Jingning; Byun, Jinyoung; Han, Younghun; Saunders, Gretchen R B; Liu, Dajiang; Bray, Michael J; Ramsey, Alex T; McKay, James; Bierut, Laura J; Amos, Christopher I; Hung, Rayjean J; Lin, Xihong; Zhang, Haoyu; Chen, Li-Shiun
  3. EBioMedicine. 2024, Nov 08; 110: 105441.
  1. 9.   Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal
  2. Rink,Connie; Kroupa, Tomas; Rein,Alan; Datta,Siddhartha
  3. Viruses. 2024, Sep 25; 16(10): 1517.
  1. 10.   A novel pathogenic germline chromosome 3 inversion in von Hippel-Lindau disease
  2. Vocke, Cathy D; Ricketts, Christopher J; Pack, Svetlana; Raffeld, Mark; Hewitt, Stephen; Lebensohn, Alexandra P; O'Brien, Lidenys; Gautam, Rabindra; Reynolds, Krista; Schmidt,Laura; Choo, Kristin; Kenigsberg, Alex; Gurram, Sandeep; Chew, Emily Y; Nilubol, Naris; Chittaboina, Prashant; Merino, Maria J; Ball, Mark W; Linehan, W Marston
  3. Journal of Medical Genetics. 2024, Sep 24;
  1. 11.   Impact of baseline SARS-CoV-2 load in plasma and upper airways on the incidence of acute extrapulmonary complications of COVID-19: a multicentric, prospective, cohort study
  2. Jensen, Tomas O; Harper, Katrina; Gupta, Shaili; Liu, Sean T; Dharan, Nila J; Baker, Jason V; Pett, Sarah L; Shaw-Saliba, Kathryn; Esmail, Aliasgar; Ho, Minh Q; Almasri, Eyad; Dewar,Robin; Lundgren, Jens; Vock, David M
  3. Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America. 2024, Sep 13;
  1. 12.   Telomere length and clonal chromosomal alterations in peripheral blood of patients with severe aplastic anaemia
  2. Strauss, Joshua D; Brown, Derek W; Zhou, Weiyin; Dagnall,Casey; Yuan, Jian-Min; Im, Annie; Savage, Sharon A; Wang, Youjin; Rafati, Maryam; Spellman, Stephen R; Gadalla, Shahinaz M
  3. British Journal of Haematology. 2024, Aug 05;
  1. 13.   Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors
  2. Kundu, Biswajit; Dvorácskó, Szabolcs; Basu, Abhishek; Pommerolle, Lenny; Kim, Kyu Ah; Wood, Casey M; Gibbs, Eve; Behee, Madeline; Tarasova,Nadya; Cinar, Resat; Iyer, Malliga R
  3. Molecules (Basel, Switzerland). 2024, Jun 26; 29(13):
  1. 14.   Phase II study of vemurafenib in children and young adults with tumors harboring BRAF V600 mutations: NCI-COG pediatric MATCH trial (APEC1621) Arm G
  2. Nelson, Marie V; Kim, AeRang; Williams,Mickey; Roy-Chowdhuri, Sinchita; Patton, David R; Coffey, Brent D; Reid, Joel M; Piao, Jin; Saguilig, Lauren; Alonzo, Todd A; Berg, Stacey L; Ramirez, Nilsa C; Jaju, Alok; Fox, Elizabeth; Weigel, Brenda J; Hawkins, Douglas S; Mooney, Margaret M; Takebe, Naoko; Tricoli, James V; Janeway, Katherine A; Seibel, Nita L; Parsons, D Williams
  3. The Oncologist. 2024, Jun 14;
  1. 15.   Correlation of protein binding pocket properties with hits' chemistries used in generation of ultra-large virtual libraries
  2. Song, Robert X; Nicklaus,Marc; Tarasova,Nadya
  3. Journal of Computer-Aided Molecular Design. 2024, May 16; 38(1): 22.
  1. 16.   Effects of Xylanase A double mutation on substrate specificity and structural dynamics
  2. MacDonald, Meagan E; Wells, Nicholas G M; Hassan,Bakar; Dudley, Joshua A; Walters,Kylie; Korzhnev, Dmitry M; Aramini, James M; Smith, Colin A
  3. Journal of Structural Biology. 2024, Mar 02; 108082.
  1. 17.   Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models
  2. Hogan, Chad H; Owens, Shana M; Reynoso, Glennys V; Liao, Yifei; Meyer,Thomas; Zelazowska, Monika A; Liu, Bin; Li, Xiaofan; Grosskopf, Anna K; Khairallah, Camille; Kirillov, Varvara; Reich, Nancy C; Sheridan, Brian S; McBride, Kevin M; Gewurz, Benjamin E; Hickman, Heather D; Forrest, J Craig; Krug, Laurie T
  3. mBio. 2024, Jan 03; e0299823.
  1. 18.   Cancer and Autism: How PTEN Mutations Degrade Function at the Membrane and Isoform Expression in the Human Brain
  2. Jang,Hyunbum; Chen, Jiaye; Iakoucheva, Lilia M; Nussinov,Ruth
  3. Journal of Molecular Biology. 2023, Dec 15; 435(24): 168354.
  1. 19.   Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses
  2. Normandin, Erica; Triana, Sergio; Raju, Siddharth S; Lan, Tammy C T; Lagerborg, Kim; Rudy, Melissa; Adams, Gordon C; DeRuff, Katherine C; Logue, James; Liu, David; Strebinger, Daniel; Rao, Arya; Messer, Katelyn S; Sacks, Molly; Adams, Ricky D; Janosko, Krisztina; Kotliar, Dylan; Shah, Rickey; Crozier,Ian; Rinn, John L; Melé, Marta; Honko, Anna N; Zhang, Feng; Babadi, Mehrtash; Luban, Jeremy; Bennett, Richard S; Shalek, Alex K; Barkas, Nikolaos; Lin, Aaron E; Hensley, Lisa E; Sabeti, Pardis C; Siddle, Katherine J
  3. Cell Genomics. 2023, Dec 13; 3(12): 100440.
  1. 20.   Perspectives of adults with neurofibromatosis regarding the design of psychosocial trials: Results from an anonymous online survey
  2. Wolters, Pamela L; Al Ghriwati,Nour; Baker, Melissa; Martin, Staci; Berg, Dale; Erickson, Gregg; Franklin, Barbara; Merker, Vanessa L; Oberlander, Beverly; Reeve, Stephanie; Rohl, Claas; Rosser, Tena; Vranceanu, Ana-Maria
  3. Clinical Trials (London, England). 2023, Nov 14;
  1. 21.   Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions
  2. Lam, Norris; Finney, Richard; Yang, Shicheng; Choi, Stephanie; Wu,Xiaolin; Cutmore, Lauren; Andrade, Jorge; Huang, Lei; Amatya, Christina; Cam, Margaret; Kochenderfer, James N
  3. Molecular Therapy Oncolytics. 2023, Sep 21; 30: 132-149.
  1. 22.   An Investigation of Structure-Activity Relationships and Cell Death Mechanisms of the Marine Alkaloids Discorhabdins in Merkel Cell Carcinoma Cells
  2. Orfanoudaki,Maria; Smith,Emily; Hill, Natasha T; Garman, Khalid A; Brownell, Isaac; Copp, Brent R; Grkovic,Tanja; Henrich,Curtis
  3. Marine Drugs. 2023, Aug 29; 21(9):
  1. 23.   Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation
  2. Geffen, Yifat; Anand, Shankara; Akiyama, Yo; Yaron, Tomer M; Song, Yizhe; Johnson, Jared L; Govindan, Akshay; Babur, Özgün; Li, Yize; Huntsman, Emily; Wang, Liang-Bo; Birger, Chet; Heiman, David I; Zhang, Qing; Miller, Mendy; Maruvka, Yosef E; Haradhvala, Nicholas J; Calinawan, Anna; Belkin, Saveliy; Kerelsky, Alexander; Clauser, Karl R; Krug, Karsten; Satpathy, Shankha; Payne, Samuel H; Mani, D R; Gillette, Michael A; Dhanasekaran, Saravana M; Thiagarajan,Mathangi; Mesri, Mehdi; Rodriguez, Henry; Robles, Ana I; Carr, Steven A; Lazar, Alexander J; Aguet, François; Cantley, Lewis C; Ding, Li; Getz, Gad
  3. Cell. 2023, Aug 09;
  1. 24.   Imaging the cellular response to an antigen tagged interstrand crosslinking agent
  2. Bellani, Marina A; Huang, Jing; Zhang, Jing; Gali,Himabindu; Thazhathveetil, Arun Kalliat; Pokharel, Durga; Majumdar, Ishani; Shaik, Althaf; Seidman, Michael M
  3. DNA Repair. 2023, Jun 09; 128: 103525.
  1. 25.   Reproducibility metrics for context-specific CRISPR screens
  2. Billmann, Maximilian; Ward, Henry N; Aregger,Michael; Costanzo, Michael; Andrews, Brenda J; Boone, Charles; Moffat, Jason; Myers, Chad L
  3. Cell Systems. 2023, May 17; 14(5): 418-422.e2.
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