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  1. 1.   Aberrant CD8+T cells drive reproductive dysfunction in female mice with elevated IFN-gamma levels
  2. Bafor, Enitome E; Erwin-Cohen, Rebecca A; Martin, Toni; Baker, Clayton; Kimmel, Adrienne E; Duverger, Olivier; Fenimore, John M; Ramba, Meredith; Spindel, Thea; Hess, Megan M; Sanford, Michael; Lazarevic, Vanja; Benayoun, Bérénice A; Young, Howard A; Valencia, Julio C
  3. Frontiers in Immunology. 2024, Apr 18; 15: 1368572.
  1. 2.   Systemic inflammatory Th1 cytokines during Trypanosoma cruzi infection disrupt the typical anatomical cell distribution and phenotypic/functional characteristics of various cell subsets within the thymus
  2. Viano, Estefania; Baez, Natalia S; Savid-Frontera, Constanza; Baigorrí, Eliana; Dinatale, Brenda; Pacini, Maria Florencia; Bulfoni Balbi, Camila; Gonzalez, Florencia Belén; Fozzatti, Laura; Lidón, Nicolas L; Young,Howard; Hodge, Deborah; Cerban, Fabio; Stempin, Cinthia; Pérez, Ana Rosa; Rodriguez Galán, Maria Cecilia
  3. Microbes and Infection. 2024, Apr 12; 105337.
  1. 3.   A neuron-immune circuit regulates neurodegeneration in the hindbrain and spinal cord of Arf1-ablated mice
  2. Wang, Guohao; Jin, Shuhan; Liu, Jiaqi; Li, Xu; Dai, Peng; Wang, Yuetong; Hou, Steven X
  3. National Science Review. 2023, Dec; 10(12): nwad222.
  1. 4.   IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
  2. Andrews, Caroline; McLean, Mairi H; Hixon,Julie; Pontejo, Sergio M; Starr, Tregei; Malo, Courtney; Cam, Margaret; Ridnour, Lisa; Hickman, Heather; Steele-Mortimer, Olivia; Wink,David; Young,Howard; McVicar,Daniel; Li,Wenqing; Durum,Scott
  3. Frontiers in Immunology. 2023, Apr 20; 14: 1021824.
  1. 5.   Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis
  2. Bomfim, Caio C B; Fisher, Logan; Amaral, Eduardo P; Mittereder, Lara; McCann, Katelyn; Correa, André A S; Namasivayam, Sivaranjani; Swamydas, Muthulekha; Moayeri, Mahtab; Weiss,Jonathan; Chari,Raj; McVicar,Daniel; Costa, Diego L; D'Império Lima, Maria R; Sher, Alan
  3. Frontiers in Cellular and Infection Microbiology. 2022, May 2; 12: 862582.
  1. 6.   Reduced Antibodies and Innate Cytokine Changes in SARS-CoV-2 BNT162b2 mRNA Vaccinated Transplant Patients With Hematological Malignancies
  2. Bergamaschi, Cristina; Pagoni, Maria; Rosati,Margherita; Angel, Matthew; Tzannou, Ifigeneia; Vlachou, Margarita; Darmani, Ismini; Ullah,Amirah; Bear,Jenifer; Devasundaram,Santhi; Burns,Robert; Baltadakis, Ioannis; Gigantes, Stavros; Dimopoulos, Meletios-Athanasios; Pavlakis,George; Terpos, Evangelos; Felber,Barbara
  3. Frontiers in Immunology. 2022 13: 899972.
  1. 7.   Safety levels of systemic IL-12 induced by cDNA expression as a cancer therapeutic
  2. Savid-Frontera, Constanza; Viano, Maria E; Baez, Natalia S; Reynolds, Della; Matellon, Mariana; Young,Howard; Rodriguez-Galan, Maria C
  3. Immunotherapy. 2021, Nov 16;
  1. 8.   Systemic IL-15, IFN-?, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
  2. Bergamaschi,Cristina; Terpos, Evangelos; Rosati,Margherita; Angel,Matthew; Bear,Jenifer; Stellas,Dimitris; Karaliota,Sevasti; Apostolakou, Filia; Bagratuni, Tina; Patseas, Dimitris; Gumeni, Sentiljana; Trougakos, Ioannis P; Dimopoulos, Meletios A; Felber,Barbara; Pavlakis,George
  3. Cell reports. 2021, Aug 10; 36(6): 109504.
  1. 9.   Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model
  2. El Meskini,Rajaa; Atkinson,Devon; Kulaga, Alan; Abdelmaksoud,Abdalla; Gumprecht, Michelle; Pate, Nathan; Hayes, Susana; Oberst, Michael; Kaplan, Ian M.; Raber, Patrick; Van Dyke, Terry; Sharan,Shyam; Hollingsworth, Robert; Day, Chi-Ping; Merlino, Glenn; Ohler,Zoe
  3. Molecular cancer research : MCR. 2021, Aug 1; 19(8): 1422-1436.
  1. 10.   IFN gamma Is a Key Link between Obesity and Th1-Mediated AutoImmune Diseases
  2. Bae,Heekyong; Choi, Myung-Sook; Kim, Suntae; Young,Howard; Gershwin, M. Eric; Jeon, Seon-Min; Kwon, Eun-Young
  3. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021, Jan; 22(1):
  1. 11.   Type I IFN signaling in T regulatory cells modulates chemokine production and myeloid derived suppressor cells trafficking during EAE
  2. Tanwar, Shalini; Oguz,Cihan; Metidji, Amina; Dahlstrom, Eric; Barbian, Kent; Kanakabandi, Kishore; Sykora, Lydia; Shevach, Ethan M
  3. Journal of autoimmunity. 2020, DEC; 115: 102525.
  1. 12.   Adaptive in vivo device for theranostics of inflammation: real-time monitoring of interferon-? and aspirin
  2. Cao, Chaomin; Jin, Ronghua; Wei, Hui; Liu, Zhongning; Ni, Shengnan; Liu, Guo-Jun; Young,Howard; Chen, Xin; Liu, Guozhen
  3. Acta biomaterialia. 2020, Jan 1; 101: 372-383.
  1. 13.   Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons
  2. Forero, Adriana; Ozarkar, Snehal; Li,Hongchuan; Lee, Chia Heng; Hemann, Emily A; Nadjsombati, Marija S; Hendricks, Matthew R; So, Lomon; Green, Richard; Roy, Chandra N; Sarkar, Saumendra N; von Moltke, Jakob; Anderson,Steve; Gale, Michael; Savan, Ram
  3. Immunity. 2019, SEP 17; 51(3): 451-+.
  1. 14.   HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways
  2. Alam, Md Masud; Yang, De; Trivett, Anna; Meyer, Thomas; Oppenheim, Joost
  3. Frontiers in immunology. 2018, Dec 18; 9: 2982.
  1. 15.   Inherited p40(phox) deficiency differs from classic chronic granulomatous disease
  2. van de Geer, Annemarie; Nieto-Patlan, Alejandro; Kuhns, Doug; Tool, Anton T. J.; Arias, Andres A.; Bouaziz, Matthieu; de Boer, Martin; Luis Franco, Jose; Gazendam, Roel P.; van Hamme, John L.; van Houdt, Michel; van Leeuwen, Karin; Verkuijlen, Paul J. H.; van den Berg, Timo K.; Alzate, Juan F.; Arango-Franco, Carlos A.; Batura, Vritika; Bernasconi, Andrea R.; Boardman, Barbara; Booth, Claire; Burns, Siobhan O.; Cabarcas, Felipe; Bensussan, Nadine Cerf; Charbit-Henrion, Fabienne; Corveleyn, Anniek; Deswarte, Caroline; Esnaola Azcoiti, Maria; Foell, Dirk; Gallin, John I.; Garces, Carlos; Guedes, Margarida; Hinze, Claas H.; Holland, Steven M.; Hughes, Stephen M.; Ibanez, Patricio; Malech, Harry L.; Meyts, Isabelle; Moncada-Velez, Marcela; Moriya, Kunihiko; Neves, Esmeralda; Oleastro, Matias; Perez, Laura; Rattina, Vimel; Oleaga-Quintas, Carmen; Warner, Neil; Muise, Aleixo M.; Serafin Lopez, Jeanet; Trindade, Eunice; Vasconcelos, Julia; Vermeire, Severine; Wittkowski, Helmut; Worth, Austen; Abel, Laurent; Dinauer, Mary C.; Arkwright, Peter D.; Roos, Dirk; Casanova, Jean-Laurent; Kuijpers, Taco W.; Bustamante, Jacinta
  3. Journal of Clinical Investigation. 2018, Aug 31; 128(9): 3957-3975.
  1. 16.   Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages
  2. Bayik, Defne; Tross, Debra; Klinman, Dennis
  3. Frontiers in immunology. 2018, Mar 26; 9: 608.
  1. 17.   Regulation of IFN-gamma Expression
  2. Fenimore, John; Young, Howard
  3. Advances in Experimental Medicine and Biology. 2016 941: 1-19.
  1. 18.   Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy
  2. Tietze, J. K.; Wilkins, D. E. C.; Sckisel, G. D.; Bouchlaka, M. N.; Alderson, K. L.; Weiss, J. M.; Ames, E.; Bruhn, K. W.; Craft, N.; Wiltrout, R. H.; Longo, D. L.; Lanier, L. L.; Blazar, B. R.; Redelman, D.; Murphy, W. J.
  3. Blood. 2012, Mar; 119(13): 3073-3083.
  1. 19.   IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors
  2. Kerkar, S. P.; Goldszmid, R. S.; Muranski, P.; Chinnasamy, D.; Yu, Z. Y.; Reger, R. N.; Leonardi, A. J.; Morgan, R. A.; Wang, E.; Marincola, F. M.; Trinchieri, G.; Rosenberg, S. A.; Restifo, N. P.
  3. Journal of Clinical Investigation. 2011, Dec; 121(12): 4746-4757.
  1. 20.   Epigenetic regulation of CIITA expression in human T-cells
  2. van Eggermond, M.; Boom, D. R.; Klous, P.; Schooten, E.; Marquez, V. E.; Wierda, R. J.; Holling, T. M.; van den Eisen, P. J.
  3. Biochemical Pharmacology. 2011, Nov; 82(10): 1430-1437.
  1. 21.   Ex vivo functional responses to HLA-G differ between blood and decidual NK cells
  2. Apps, R.; Sharkey, A.; Gardner, L.; Male, V.; Kennedy, P.; Masters, L.; Farrell, L.; Jones, D.; Thomas, R.; Moffett, A.
  3. Molecular Human Reproduction. 2011, Sep; 17(9): 577-586.
  1. 22.   CD8 alpha(+) Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites
  2. Mashayekhi, M.; Sandau, M. M.; Dunay, I. R.; Frickel, E. M.; Khan, A.; Goldszmid, R. S.; Sher, A.; Ploegh, H. L.; Murphy, T. L.; Sibley, L. D.; Murphy, K. M.
  3. Immunity. 2011, Aug; 35(2): 249-259.
  1. 23.   Secretoglobin 3A2 Suppresses Bleomycin-induced Pulmonary Fibrosis by Transforming Growth Factor beta Signaling Down-regulation
  2. Kurotani, R.; Okumura, S.; Matsubara, T.; Yokoyama, U.; Buckley, J. R.; Tomita, T.; Kezuka, K.; Nagano, T.; Esposito, D.; Taylor, T. E.; Gillette, W. K.; Ishikawa, Y.; Abe, H.; Ward, J. M.; Kimura, S.
  3. Journal of Biological Chemistry. 2011, Jun; 286(22): 19682-19692.
  1. 24.   Localized Delivery of Interferon-beta by Lactobacillus Exacerbates Experimental Colitis
  2. McFarl, A. P.; Savan, R.; Wagage, S.; Addison, A.; Ramakrishnan, K.; Karwan, M.; Tri, D.; Young, H. A.
  3. Plos One. 2011, Feb; 6(2): 13.
  1. 25.   CCL5: A Double-Edged Sword in Host Defense Against the Hepatitis C Virus
  2. Katsounas, A.; Schlaak, J. F.; Lempicki, R. A.
  3. International Reviews of Immunology. 2011, Oct-Dec; 30(5-6): 366-378.
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