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  1. 1.   Chronic Low-Level IFN-gamma Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis
  2. Bae, Heekyong R; Shin, Su-Kyung; Lee, Ji-Yoon; Ko, Yeo Jin; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. International Journal of Molecular Sciences. 2024, Dec 25; 26(1):
  1. 2.   Interleukin-2-mediated NF-kB-dependent mRNA splicing modulates interferon gamma protein production
  2. Van Gelder, Rachel D; Gokhale, Nandan S; Genoyer, Emmanuelle; Omelia, Dylan S; Anderson,Steve; Young,Howard; Savan, Ram
  3. EMBO Reports. 2024, Nov 22;
  1. 3.   Severe Clinical Phenotypes of Heterozygous Females With X-Linked Chronic Granulomatous Disease
  2. Patel, Niraj C; Younger, M Elizabeth M; Williams, Kelli; Matias Lopes, Joao Pedro; Kuhns,Doug; Patel, Meera N; Miranda, Mary Ann; Marciano, Beatriz E; Deal, Christin Lawler; Leiding, Jennifer W
  3. The journal of Allergy and Clinical Immunology. In Practice. 2024, Sep 25;
  1. 4.   IFN-gamma: A cytokine at the right time, is in the right place
  2. Burke,Daniel; Young,Howard
  3. Seminars in immunology. 2019, JUN; 43(Special Issue: SI):
  1. 5.   Structural conservation of interferon gamma among vertebrates
  2. Savan, R.; Ravichandran, S.; Collins, J. R.; Sakai, M.; Young, H. A.
  3. Cytokine & Growth Factor Reviews. 2009 20(2): 115-124.
  1. 6.   Unraveling the pros and cons of interferon-gamma gene regulation
  2. Young, H. A.
  3. Immunity. 2006, MAY; 24(5): 506-507.
  1. 7.   Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
  2. Fuss, I. J.; Becker, C.; Yang, Z. Q.; Groden, C.; Hornung, R. L.; Heller, F.; Neurath, M. F.; Strober, W.; Mannon, P. J.
  3. Inflammatory Bowel Diseases. 2006, JAN; 12(1): 9-15.
  1. 8.   Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV Gag
  2. Zhao, J.; Voltan, R.; Peng, B.; vis-Warren, A.; Kalyanaraman, V. S.; Alvord, W. G.; Aldrich, K.; Bernasconi, D.; Butto, S.; Cafaro, A.; Ensoli, B.; Robert-Guroff, M.
  3. Virology. 2005, NOV 10; 342(1): 1-12.
  1. 9.   A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-beta-dependent gene expression in response to interferon-gamma
  2. Roy, S. K.; Shuman, J. D.; Platanias, L. C.; Shapiro, P. S.; Reddy, S. P. M.; Johnson, P. F.; Kalvakolanu, D. V.
  3. Journal of Biological Chemistry. 2005, JUL 1; 280(26): 24462-24471.
  1. 10.   Interferon-gamma and collagen synergistically induce monocyte chemoattractant protein-1 production in human polymorphonuclear leukocytes (PMN): Role of discoidin domain receptor 1 (DDR1)
  2. Yoshimura, T.; Matsuyama, W.; Mizuta, H.; Matsukawa, A.
  3. Faseb Journal. 2005, MAR 4; 19(4, Part 1 Suppl. S): A10-A10.
  1. 11.   Enhanced immunity and protective efficacy against SIVmac251 intrarectal challenge following Ad-SIV priming by multiple mucosal routes and gp120 boosting in MPL-SE
  2. Pinczewski, J.; Zhao, J.; Malkevitch, N.; Patterson, L. J.; Aldrich, K.; Alvord, W. G.; Robert-Guroff, M.
  3. Viral Immunology. 2005, SPR; 18(1): 236-243.
  1. 12.   Peroxisome proliferator-activated receptor-gamma and its ligands attenuate biologic functions of human natural killer cells
  2. Zhang, X.; Rodriguez-Galan, M. C.; Subleski, J. J.; Ortaldo, J. R.; Hodge, D. L.; Wang, J. M.; Shimozato, O.; Reynolds, D. A.; Young, H. A.
  3. Blood. 2004, NOV 15; 104(10): 3276-3284.
  1. 13.   A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2
  2. Bream, J. H.; Hodge, D. L.; Gonsky, R.; Spolski, R.; Leonard, W. J.; Krebs, S.; Targan, S.; Morinobu, A.; O'Shea, J. J.; Young, H. A.
  3. Journal of Biological Chemistry. 2004, SEP 24; 279(39): 41249-41257.
  1. 14.   PPAR-gamma represses interferon-gamma gene expression by sequestration of CBP/p300
  2. Zhang, X.; Young, H. A.
  3. Faseb Journal. 2004 18(5, Suppl. S): A1138-A1138.
  1. 15.   Human CD8(+) T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation
  2. Catalfamo, M.; Karpova, T.; McNally, J.; Costes, S. V.; Lockett, S. J.; Bos, E.; Peters, P. J.; Henkart, P. A.
  3. Immunity. 2004 20(2): 219-230.
  1. 16.   Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection
  2. Gloster, S. E.; Newton, P.; Cornforth, D.; Lifson, J. D.; Williams, I.; Shaw, G. M.; Borrow, P.
  3. Aids. 2004 18(5): 749-755.
  1. 17.   Picolinic acid- or desferrioxamine-inducible autocrine activation of macrophages engineered to produce IFN gamma: an approach for gene therapy
  2. Pastorino, S.; Carta, L.; Puppo, M.; Melillo, G.; Bosco, M. C.; Varesio, L.
  3. Gene Therapy. 2004 11(6): 560-568.
  1. 18.   Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
  2. Kershaw, M. H.; Wang, G.; Westwood, J. A.; Pachynski, R. K.; Tiffany, H. L.; Marincola, F. M.; Wang, E.; Young, H. A.; Murphy, P. M.; Hwu, P.
  3. Human Gene Therapy. 2002 13(16): 1971-1980.
  1. 19.   Polymorphisms of the human IFNG gene noncoding regions
  2. Bream, J. H.; Carrington, M.; O'Toole, S.; Dean, M.; Gerrard, B.; Shin, H. D.; Kosack, D.; Modi, W.; Young, H. A.; Smith, M. W.
  3. Immunogenetics. 2000 51(1): 50-58.
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