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  1. 1.   Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids
  2. Coussens,Nathan; Dexheimer,Thomas; Silvers,Thomas; Sanchez,Phillip; Chen,Li; Hollingshead, Melinda G; Takebe, Naoko; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2025, Apr 08; 100230.
  1. 2.   Ror gamma t-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
  2. Rodrigues, Patrick Fernandes; Wu, Shitong; Trsan, Tihana; Panda, Santosh K; Fachi, José Luís; Liu, Yizhou; Du, Siling; de Oliveira, Sarah; Antonova, Alina Ulezko; Khantakova, Darya; Sudan, Raki; Desai, Pritesh; Diamond, Michael S; Gilfillan, Susan; Anderson,Stephen; Cella, Marina; Colonna, Marco
  3. Cell. 2025, Apr 01;
  1. 3.   PLS-a-GalCer: a novel targeted glycolipid therapy for solid tumors
  2. Burks, Julian; Tiwary, Shweta; Stevens, David M; Skoczen,Sarah; Kularatne,Ruvanthi Nilanga; Stern,Stephan; Berzofsky, Jay A
  3. Journal for Immunotherapy of Cancer. 2025, Mar 22; 13(3):
  1. 4.   Neolignan and 3-Benzylchroman Derivatives From Celastrus orbiculatus Thunb
  2. Hua, Silu; Liu, Ping; Miao, Li; Zhang, Likui; Wang, Haibo; Liu, Yanqing; Wang,Dongdong; Jiang, Wei
  3. Chemistry & Biodiversity. 2025, Mar 18; e202500273.
  1. 5.   Purification and characterization of full-length monomeric TEC family kinase, ITK
  2. Rathnayake, Udumbara M; Wada, Junya; Wall, Vanessa E; Jones,Jane; Jenkins, Lisa M; Andreotti, Amy H; Samelson, Lawrence E
  3. Protein Expression and Purification. 2025, Jan 31; 229: 106682.
  1. 6.   Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of OXi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents
  2. Vairin, Rebecca; Tamminga, Caleb; Shi, Zhe; Borchardt, Christian; Jambulapati, Jayaram; Bai, Ruoli; Wanniarachchi, Hashini; Bueno, Lorena; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2024, Nov 07; 118: 117981.
  1. 7.   Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale
  2. Zhang, Weici; Al Tekreeti, Taha; Leung, Patrick S C; Tsuneyama, Koichi; Dhillon, Harleen; Rojas, Manuel; Heuer, Luke S; Ridgway, William M; Ansari, Aftab A; Young,Howard; Mackay, Charles R; Gershwin, M Eric
  3. Liver International : official journal of the International Association for the Study of the Liver. 2024, Aug 05;
  1. 8.   Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
  2. Das, Arundhoti; Martinez-Ruiz, Gustavo Ulises; Bouladoux, Nicolas; Stacy, Apollo; Moraly, Josquin; Vega-Sendino, Maria; Zhao, Yongge; Lavaert, Marieke; Ding, Yi; Morales-Sanchez, Abigail; Harly, Christelle; Seedhom, Mina O; Chari,Raj; Awasthi, Parirokh; Ikeuchi, Tomoko; Wang, Yueqiang; Zhu, Jinfang; Moutsopoulos, Niki M; Chen, WanJun; Yewdell, Jonathan W; Shapiro, Virginia Smith; Ruiz, Sergio; Taylor, Naomi; Belkaid, Yasmine; Bhandoola, Avinash
  3. Immunity. 2024, May 14; 57(5): 1019-1036.
  1. 9.   Shared and distinct mechanisms of UBA1 inactivation across different diseases
  2. Collins, Jason C; Magaziner, Samuel J; English, Maya; Hassan,Bakar; Chen,Xiang; Balanda, Nicholas; Anderson, Meghan; Lam, Athena; Fernandez-Pol, Sebastian; Kwong, Bernice; Greenberg, Peter L; Terrier, Benjamin; Likhite, Mary E; Kosmider, Olivier; Wang, Yan; Samara, Nadine L; Walters,Kylie; Beck, David B; Werner, Achim
  3. The EMBO Journal. 2024, May; 43(10): 1919-1946.
  1. 10.   Disruption of Ca2+/calmodulin:KSR1 interaction lowers ERK activation
  2. Thines, Louise; Jang,Hyunbum; Li, Zhigang; Sayedyahossein, Samar; Maloney, Ryan; Nussinov,Ruth; Sacks, David B
  3. Protein Science : a publication of the Protein Society. 2024, May; 33(5): e4982.
  1. 11.   Effects of Xylanase A double mutation on substrate specificity and structural dynamics
  2. MacDonald, Meagan E; Wells, Nicholas G M; Hassan,Bakar; Dudley, Joshua A; Walters,Kylie; Korzhnev, Dmitry M; Aramini, James M; Smith, Colin A
  3. Journal of Structural Biology. 2024, Mar 02; 108082.
  1. 12.   Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
  2. Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu,Xia; Andresson,Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer,Thomas; Hartmann, Oliver; Diefenbacher, Markus E; Pommier, Yves; Weyemi, Urbain
  3. Molecular Carcinogenesis. 2024, Feb 27;
  1. 13.   SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
  2. Ohara, Yuuki; Tang, Wei; Liu, Huaitian; Yang, Shouhui; Dorsey, Tiffany H; Cawley, Helen; Moreno, Paloma; Chari,Raj; Guest,Mary; Azizian, Azadeh; Gaedcke, Jochen; Ghadimi, Michael; Hanna, Nader; Ambs, Stefan; Hussain, S Perwez
  3. Cell Reports. 2023, Nov 18; 42(12): 113434.
  1. 14.   Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum
  2. Bennett, John M; Ward, Kurt E; Muir, Ryan K; Kabeche, Stephanie; Yoo,Euna; Yeo, Tomas; Lam, Grace; Zhang, Hao; Almaliti, Jehad; Berger, Gabriel; Faucher, Franco F; Lin, Gang; Gerwick, William H; Yeh, Ellen; Fidock, David A; Bogyo, Matthew
  3. ACS Infectious Diseases. 2023, Oct 13; 9(10): 2036-2047.
  1. 15.   HLA-DP on Epithelial Cells enables Tissue Damage by NKp44+ NK Cells in Ulcerative Colitis
  2. Baumdick, Martin E; Niehrs, Annika; Degenhardt, Frauke; Schwerk, Maria; Hinrichs, Ole; Jordan-Paiz, Ana; Padoan, Benedetta; Wegner, Lucy H M; Schloer, Sebastian; Zecher, Britta F; Malsy, Jakob; Joshi, Vinita R; Illig, Christin; Schröder-Schwarz, Jennifer; Möller, Kimberly J; Martin,Pat; Yuki,Yuko; Ozawa, Mikki; Sauter, Jürgen; Schmidt, Alexander H; Perez, Daniel; Giannou, Anastasios D; Carrington, Mary; Davis, Randall S; Schumacher, Udo; Sauter, Guido; Huber, Samuel; Puelles, Victor G; Melling, Nathaniel; Franke, Andre; Altfeld, Marcus; Bunders, Madeleine J
  3. Gastroenterology. 2023, Oct; 165(4): 946-962.e13..
  1. 16.   Rare disease variant curation from literature: assessing gaps with creatine transport deficiency in focus
  2. Lyons,Erica; Watson,Daniel; Alodadi,Mohammad; Haugabook, Sharie J; Tawa, Gregory J; Hannah-Shmouni, Fady; Porter, Forbes D; Collins, Jack R; Ottinger, Elizabeth A; Mudunuri,Uma
  3. BMC Genomics. 2023, Aug 16; 24(1): 460.
  1. 17.   Plasmodium falciparum malaria is associated with increased KSHV seropositivity and higher KSHV antibody breadth and magnitude: results of a case-control study from rural Uganda
  2. Nalwoga, Angela; Sabourin, Katherine R; Miley,Wendell; Jackson, Conner; Maktabi, Mahdi; Labo,Nazzarena; Mugisha, Joseph; Whitby,Denise; Rochford, Rosemary; Newton, Robert
  3. The Journal of Infectious Diseases. 2023, Aug 04;
  1. 18.   ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer
  2. Schultz, Christopher W; Zhang, Yang; Elmeskini, Rajaa; Zimmermann, Astrid; Fu, Haiqing; Murai, Yasuhisa; Wangsa, Darawalee; Kumar, Suresh; Takahashi, Nobuyuki; Atkinson,Devon; Saha, Liton Kumar; Lee, Chien-Fei; Elenbaas, Brian; Desai, Parth; Sebastian, Robin; Sharma, Ajit Kumar; Abel, Melissa; Schroeder, Brett; Krishnamurthy, Manan; Kumar, Rajesh; Roper, Nitin; Aladjem, Mirit; Zenke, Frank T; Ohler,Zoe; Pommier, Yves; Thomas, Anish
  3. EMBO Molecular Medicine. 2023, Jul 25; e17313.
  1. 19.   Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinoma
  2. Jikuya, Ryosuke; Johnson, Todd A; Maejima, Kazuhiro; An, Jisong; Ju, Young-Seok; Lee, Hwajin; Ha, Kyungsik; Song, WooJeung; Kim, Youngwook; Okawa, Yuki; Sasagawa, Shota; Kanazashi, Yuki; Fujita, Masashi; Imoto, Seiya; Mitome, Taku; Ohtake, Shinji; Noguchi, Go; Kawaura, Sachi; Iribe, Yasuhiro; Aomori, Kota; Tatenuma, Tomoyuki; Komeya, Mitsuru; Ito, Hiroki; Ito, Yusuke; Muraoka, Kentaro; Furuya, Mitsuko; Kato, Ikuma; Fujii, Satoshi; Hamanoue, Haruka; Tamura, Tomohiko; Baba, Masaya; Suda, Toshio; Kodama, Tatsuhiko; Makiyama, Kazuhide; Yao, Masahiro; Shuch, Brian M; Ricketts, Christopher J; Schmidt,Laura; Linehan, W Marston; Nakagawa, Hidewaki; Hasumi, Hisashi
  3. EBioMedicine. 2023, May 12; 92: 104596.
  1. 20.   Clinical evaluation of commercial SARS-CoV-2 serological assays in a malaria endemic setting
  2. Dabitao, Djeneba; Shaw-Saliba, Kathryn; Konate, Drissa S; Highbarger,Helene; Lallemand,Perrine; Sanogo, Ibrahim; Rehman,Tauseef; Wague, Mamadou; Coulibaly, Nadie; Kone, Bourahima; Baya, Bocar; Diakite, Seidina A S; Samake, Seydou; Akpa, Esther; Tounkara, Moctar; Laverdure, Sylvain; Doumbia, Seydou; Lane, H Clifford; Diakite, Mahamadou; Dewar,Robin
  3. Journal of Immunological Methods. 2023, May 11; 113488.
  1. 21.   Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV 1.7 and hCaV 3 voltage-gated channels
  2. Giribaldi, Julien; Chemin, Jean; Tuifua, Marie; Deuis, Jennifer R; Mary, Rosanna; Vetter, Irina; Wilson, David T; Daly, Norelle L; Schroeder, Christina I; Bourinet, Emmanuel; Dutertre, Sébastien
  3. The FEBS Journal. 2023, Mar 13;
  1. 22.   The Application of Guanidinium to Improve Biomolecule Quality in Fixed, Paraffin-embedded Tissue
  2. Chung, Joon-Yong; Kim, Kyungeun; Ylaya, Kris; Walker-Bawa, Katharine E; Perry,Candice; Star, Robert A; Hewitt, Stephen M
  3. The Journal of Histochemistry and Cytochemistry : official journal of the Histochemistry Society. 2023, Mar 04; 221554231159451.
  1. 23.   Simple monocyclic pyrimidine analogs as microtubule targeting agents binding to the colchicine site
  2. Choudhary, Shruti; Kaku, Krishna; Robles, Andrew J; Hamel,Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry. 2023, Feb 24; 82: 117217.
  1. 24.   Hematologically important mutations: Leukocyte adhesion deficiency (second update)
  2. Roos, Dirk; van Leeuwen, Karin; Madkaikar, Manisha; Kambli, Priyanka M; Gupta, Maya; Mathews, Vikram; Rawat, Amit; Kuhns,Doug; Holland, Steven M; de Boer, Martin; Kanegane, Hirokazu; Parvaneh, Nima; Lorenz, Myriam; Schwarz, Klaus; Klein, Christoph; Sherkat, Roya; Jafari, Mahbube; Wolach, Baruch; den Dunnen, Johan T; Kuijpers, Taco W; Köker, M Yavuz
  3. Blood Cells, Molecules & Diseases. 2023, Jan 20; 99: 102726.
  1. 25.   A diagnosis of Birt-Hogg-Dubé syndrome in individuals with Smith-Magenis syndrome: Recommendation for cancer screening
  2. Vocke, Cathy D; Fleming, Leah R; Piskorski, Anna M; Amin, Ali; Phornphutkul, Chanika; de la Monte, Suzanne; Vilboux, Thierry; Duncan, Folami; Pellegrino, Joan; Braddock, Bonnie; Middelton, Lindsay A; Schmidt,Laura; Merino, Maria J; Cowen, Edward W; Introne, Wendy J; Linehan, W Marston; Smith, Ann C M
  3. American Journal of Medical Genetics. Part A. 2022, Dec 13;
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