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  1. 1.   Molecular Evolutionary Analysis of ABCB5: The Ancestral Gene Is a Full Transporter with Potentially Deleterious Single Nucleotide Polymorphisms
  2. Moitra, K.; Scally, M.; McGee, K.; Lancaster, G.; Gold, B.; Dean, M.
  3. Plos One. 2011, Jan; 6(1): 12.
  1. 2.   Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication
  2. Oguariri, R. M.; Adelsberger, J. W.; Baseler, M. W.; Imamichi, T.
  3. Virus Research. 2010, Nov; 153(2): 269-276.
  1. 3.   Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1
  2. Fer, N. D.; Shoemaker, R. H.; Monks, A.
  3. Journal of Experimental & Clinical Cancer Research. 2010, Jul; 29: 7.
  1. 4.   JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo
  2. Kiziltepe, T.; Anderson, K. C.; Kutok, J. L.; Jia, L.; Boucher, K. M.; Saavedra, J. E.; Keefer, L. K.; Shami, P. J.
  3. Journal of Pharmacy and Pharmacology. 2010, Jan; 62(1): 145-151.
  1. 5.   JS-K, an arylating nitric oxide (NO) donor, has synergistic anti-leukemic activity with cytarabine (ARA-C)
  2. Shami, P. J.; Maciag, A. E.; Eddington, J. K.; Udupi, V.; Kosak, K. M.; Saavedra, J. E.; Keefer, L. K.
  3. Leukemia Research. 2009 33(11): 1525-1529.
  1. 6.   Aryl Bis(diazeniumdiolates): Potent Inducers of S-Glutathionylation of Cellular Proteins and Their in Vitro Antiproliferative Activities
  2. Andrei, D.; Maciag, A. E.; Chakrapani, H.; Citro, M. L.; Keefer, L. K.; Saavedra, J. E.
  3. Journal of Medicinal Chemistry. 2008 51(24): 7944-7952.
  1. 7.   Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs
  2. Chakrapani, H.; Kalathur, R. C.; Maciag, A. E.; Citro, M. L.; Ji, X. H.; Keefer, L. K.; Saavedra, J. E.
  3. Bioorganic & Medicinal Chemistry. 2008 16(22): 9764-9771.
  1. 8.   Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole
  2. Mooberry, S. L.; Weiderhold, K. N.; Dakshanamurthy, S.; Hamel, E.; Banner, E. J.; Kharlamova, A.; Hempel, J.; Gupton, J. T.; Brown, M. L.
  3. Molecular Pharmacology. 2007, Jul; 72(1): 132-140.
  1. 9.   Proteomic analysis identifies oxidative stress induction by adaphostin
  2. Stockwin, L. H.; Bumke, M. A.; Yu, S. X.; Webb, S. P.; Collins, J. R.; Hollingshead, M. G.; Newton, D. L.
  3. Clinical Cancer Research. 2007, Jun; 13(12): 3667-3681.
  1. 10.   C/EBP alpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation
  2. Suh, H. C.; Gooya, J.; Renn, K.; Friedman, A. D.; Johnson, P. F.; Keller, J. R.
  3. Blood. 2006, Jun; 107(11): 4308-4316.
  1. 11.   Assessment of in vitro and in vivo activities in the National Cancer Institute's anticancer screen with respect to chemical structure, target specificity, and mechanism of action
  2. Huang, R. L.; Wallqvist, A.; Covell, D. G.
  3. Journal of Medicinal Chemistry. 2006, Mar; 49(6): 1964-1979.
  1. 12.   Activation of the Jun N-terminal kinase pathway by friend spleen focus-forming virus and its role in the growth and survival of friend virus-induced erythroleukemia cells
  2. Nishigaki, K.; Hanson, C.; Thompson, D.; Yugawa, T.; Ruscetti, S.
  3. Journal of Virology. 2005, OCT; 79(20): 12752-12762.
  1. 13.   PKC delta plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant
  2. Jelacic, T.; Linnekin, D.
  3. Blood. 2005, MAR 1; 105(5): 1923-1929.
  1. 14.   Cytotoxicity of RH1: NAD(P)H : quinone acceptor oxidoreductase (NQO1)-independent oxidative stress and apoptosis induction
  2. Tudor, G.; Alley, M.; Nelson, C. M.; Huang, R. L.; Covell, D. G.; Gutierrez, P.; Sausville, E. A.
  3. Anti-Cancer Drugs. 2005 16(4): 381-391.
  1. 15.   Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation
  2. Puppo, M.; Pastorino, S.; Melillo, G.; Pezzolo, A.; Varesio, L.; Bosco, M. C.
  3. Clinical Cancer Research. 2004, DEC 15; 10(24): 8704-8719.
  1. 16.   JS-K, a novel nitric oxide (NO) generator, induces cytochrome c release and caspase activation in HL-60 myeloid leukemia cells
  2. Shami, P. J.; Udupi, V.; Yu, M.; Malaviya, S.; Saavedra, J. E.; Keefer, L. K.
  3. Blood. 2004, NOV 16; 104(11, Part 1, Abstract 3415): 931A-931A.
  1. 17.   Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor
  2. Sun, R. H.; Iribarren, P.; Zhang, N.; Zhou, Y.; Gong, W. H.; Cho, E. H.; Lockett, S.; Chertov, O.; Bednar, F.; Rogers, T. J.; Oppenheim, J. J.; Wang, J. M.
  3. Journal of Immunology. 2004 173(1): 428-436.
  1. 18.   The four distal tyrosines are required for LAT-dependent signaling in Fc epsilon RI-mediated mast cell activation
  2. Saitoh, S.; Odom, S.; Gomez, G.; Sommers, C. L.; Young, H. A.; Rivera, J.; Samelson, L. E.
  3. Journal of Experimental Medicine. 2003 198(5): 831-843.
  1. 19.   ERF, an ETS-related transcriptional repressor, can induce erythroid differentiation
  2. Athanasiou, M.; Blair, D. G.; Mavrothalassitis, G.
  3. Anticancer Research. 2003, MAY-JUNE; 23(3A): 2143-2153.
  1. 20.   Marine pharmacology in 2000: Antitumor and cytotoxic compounds
  2. Mayer, A. M. S.; Gustafson, K. R.
  3. International Journal of Cancer. 2003 105(3): 291-299.
  1. 21.   Expression of Bcl-2 family member bid in normal and malignant tissues
  2. Krajewska, M.; Zapata, J. M.; Meinhold-Heerlein, I.; Hedayat, H.; Monks, A.; Bettendorf, H.; Shabaik, A.; Bubendorf, L.; Kallioniemi, O. P.; Kim, H.; Reifenberger, G.; Reed, J. C.; Krajewski, S.
  3. Neoplasia. 2002 4(2): 129-140.
  1. 22.   Cellular pharmacology studies of shikonin derivatives
  2. Chen, X.; Yang, L.; Oppenheim, J. J.; Howard, O. M. Z.
  3. Phytotherapy Research. 2002 16(3): 199-209.
  1. 23.   Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia
  2. Blaydes, S. M.; Kogan, S. C.; Truong, B. T. H.; Gilbert, D. J.; Jenkins, N. A.; Copeland, N. G.; Largaespada, D. A.; Brannan, C. I.
  3. Journal of Virology. 2001 75(19): 9427-9434.
  1. 24.   FLI-1 is a suppressor of erythroid differentiation in human hematopoietic cells
  2. Athanasiou, M.; Mavrothalassitis, G.; Sun-Hoffman, L.; Blair, D. G.
  3. Leukemia. 2000 14(3): 439-445.
  1. 25.   An informatics approach identifying markers of chemosensitivity in human cancer cell lines
  2. Amundson, S. A.; Myers, T. G.; Scudiero, D.; Kitada, S.; Reed, J. C.; Fornace, A. J.
  3. Cancer Research. 2000 60(21): 6101-6110.
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