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  1. 1.   HTLV-1 p13 Protein Hijacks Macrophage Polarization and Promotes T-Cell Recruitment
  2. Moles, Ramona; Omsland, Maria; Pise-Masison, Cynthia A; Subleski,Jeffrey; McVicar,Daniel; Sarkis, Sarkis; Gutowska, Anna; Schifanella, Luca; Doster, Melvin; Washington-Parks, Robyn; Ciminale, Vincenzo; Franchini, Genoveffa
  3. Viruses. 2025, Mar 26; 17(4): 471.
  1. 2.   Chronic Low-Level IFN-gamma Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis
  2. Bae, Heekyong R; Shin, Su-Kyung; Lee, Ji-Yoon; Ko, Yeo Jin; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. International Journal of Molecular Sciences. 2024, Dec 25; 26(1):
  1. 3.   PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
  2. Yoshida, Teruhiko; Latt, Khun Zaw; Rosenberg, Avi Z; Santo, Briana A; Myakala, Komuraiah; Ishimoto,Yu; Zhao, Yongmei; Shrivastav, Shashi; Jones, Bryce A; Yang, Xiaoping; Wang, Xiaoxin X; Tutino, Vincent M; Sarder, Pinaki; Levi, Moshe; Okamoto, Koji; Winkler, Cheryl A; Kopp, Jeffrey B
  3. eLife. 2024, Aug 29; 12
  1. 4.   Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale
  2. Zhang, Weici; Al Tekreeti, Taha; Leung, Patrick S C; Tsuneyama, Koichi; Dhillon, Harleen; Rojas, Manuel; Heuer, Luke S; Ridgway, William M; Ansari, Aftab A; Young,Howard; Mackay, Charles R; Gershwin, M Eric
  3. Liver International : official journal of the International Association for the Study of the Liver. 2024, Aug 05;
  1. 5.   NAD deficiency contributes to progressive kidney disease in HIV nephropathy mice
  2. Yoshida, Teruhiko; Myakala, Komuraiah; Jones, Bryce A; Wang, Xiaoxin X; Shrivastav, Shashi; Santo, Briana A; Patel, Tatsat R; Zhao,Yongmei; Tutino, Vincent M; Sarder, Pinaki; Rosenberg, Avi Z; Winkler,Cheryl; Levi, Moshe; Kopp, Jeffrey B
  3. American Journal of Physiology. Renal physiology. 2024, Jul 04;
  1. 6.   D-Allulose Ameliorates Dysregulated Macrophage Function and Mitochondrial NADH Homeostasis, Mitigating Obesity-Induced Insulin Resistance
  2. Bae, Heekyong R; Shin, Su-Kyung; Han, Youngji; Yoo, Ji-Hyeon; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. Nutrients. 2023, Sep 29; 15(19):
  1. 7.   Chronic inflammation in high-fat diet-fed mice: Unveiling the early pathogenic connection between liver and adipose tissue
  2. Bae, Heekyong R; Shin, Su-Kyung; Yoo, Ji-Hyeon; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. Journal of Autoimmunity. 2023, Aug 16; 139: 103091.
  1. 8.   Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration
  2. Metzger,Meredith; Scales, Jessica L; Grant, Garis A; Molnar,Abby; Loncarek,Jadranka; Weissman,Allan
  3. The Journal of Biological Chemistry. 2023, Aug; 299(8): 104937.
  1. 9.   IFN-gamma and androgens disrupt mitochondrial function in murine myocytes
  2. Fenimore, John M; Springer, Danielle A; Romero, Maria E; Edmondson,Elijah; McVicar,Daniel; Yanpallewar, Sudhirkumar; Sanford,Michael; Spindel, Thea; Engle, Elizabeth; Meyer, Thomas J; Valencia,Julio; Young,Howard
  3. The Journal of Pathology. 2023, Apr 27;
  1. 11.   Dual B-cell targeting therapy ameliorates autoimmune cholangitis
  2. Zhang, Weici; Shao, Tihong; Leung, Patrick S C; Tsuneyama, Koichi; Heuer, Luke; Young,Howard; Ridgway, William M; Gershwin, M Eric
  3. Journal of Autoimmunity. 2022, Aug 24; 132: 102897.
  1. 12.   HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCe Activation
  2. Mancardi, Daniele; Pagliaro, Pasquale; Ridnour,Lisa; Tocchetti, Carlo G; Miranda, Katrina; Juhaszova, Magdalena; Sollott, Steven J; Wink,David; Paolocci, Nazareno
  3. Antioxidants (Basel, Switzerland). 2022, Feb 14; 11(2):
  1. 13.   Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach
  2. Smith, Kyle P; Lee, Woonghee; Tonelli, Marco; Lee, Yeongjoon; Light, Samuel H; Cornilescu,Gabriel; Chakravarthy, Srinivas
  3. Protein Science : a Publication of the Protein Society. 2022, Feb 08; 31(5):
  1. 14.   Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b] thiophene derivatives as potent apoptosis-inducing agents
  2. Romagnoli, Romeo; Preti, Delia; Hamel,Ernest; Bortolozzi, Roberta; Viola, Giampietro; Brancale, Andrea; Ferla, Salvatore; Morciano, Giampaolo; Pinton, Paolo
  3. Bioorganic chemistry. 2021, Jul; 112
  1. 15.   Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation
  2. Yang, Shu; Gorshkov, Kirill; Lee, Emily M; Xu, Miao; Cheng, Yu-Shan; Sun, Nuo; Soheilian,Ferri; de Val, Natalia; Ming, Guoli; Song, Hongjun; Tang, Hengli; Zheng, Wei
  3. Frontiers in Microbiology. 2020, Dec 23; 11: 598203.
  1. 16.   Editorial: Metabolism Meets Function: Untangling the Cross-Talk Between Signaling and Metabolism
  2. Castegna, Alessandra; McVicar,Daniel; Campanella, Annalisa; Palmieri,Erika; Menga, Alessio; Porporato, Paolo E.
  3. FRONTIERS IN ONCOLOGY. 2020, OCT 20; 10: 607511.
  1. 17.   Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite
  2. Perez,Minervo; Bak, Daniel W.; Bergholtz, Sarah E.; Crooks, Daniel R.; Arimilli, Bhargav Srinivas; Yang, Youfeng; Weerapana, Eranthie; Linehan, W. Marston; Meier,Jordan
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, SEP 25; 295(39): 13410-13418.
  1. 18.   Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization
  2. Hauseman, Zachary J; Harvey, Edward P; Newman, Catherine E; Wales, Thomas E; Bucci, Joel C; Mintseris, Julian; Schweppe, Devin K; David, Liron; Fan,Lixin; Cohen, Daniel T; Herce, Henry D; Mourtada, Rida; Ben-Nun, Yael; Bloch, Noah B; Hansen, Scott B; Wu, Hao; Gygi, Steven P; Engen, John R; Walensky, Loren D
  3. Molecular cell. 2020, JUL 2; 79(1): 68-+.
  1. 19.   FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland
  2. Isono, Yasuhiro; Furuya, Mitsuko; Kuwahara, Tatsu; Sano, Daisuke; Suzuki, Kae; Jikuya, Ryosuke; Mitome, Taku; Otake, Shinji; Kawahara, Takashi; Ito, Yusuke; Muraoka, Kentaro; Nakaigawa, Noboru; Kimura, Yayoi; Baba, Masaya; Nagahama, Kiyotaka; Takahata, Hiroyuki; Saito, Ichiro; Schmidt,Laura; Linehan, W Marston; Kodama, Tatsuhiko; Yao, Masahiro; Oridate, Nobuhiko; Hasumi, Hisashi
  3. Biochemical and biophysical research communications. 2020, FEB 19; 522(4): 931-938.
  1. 20.   Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice
  2. Johnson, Jabril R; Lack,Justin; Boulanger, Corinne A; Ragle, Lauren E; Smith, Gilbert H
  3. Oncotarget. 2020, Jan 14; 11(2): 161-174.
  1. 21.   Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro
  2. Guo, Liang; Eldridge, Sandy; Furniss, Michael; Mussio, Jodie; Davis, Myrtle
  3. Toxicology and applied pharmacology. 2018, Dec 1; 360: 88-98.
  1. 22.   Monoamine oxidase-dependent histamine catabolism accounts for post-ischemic cardiac redox imbalance and injury
  2. Costiniti, Veronica; Spera, Iolanda; Menabò, Roberta; Palmieri, Erika; Menga, Alessio; Scarcia, Pasquale; Porcelli, Vito; Gissi, Rosanna; Castegna, Alessandra; Canton, Marcella
  3. Biochimica et Biophysica Acta. 2018, Sep; 1864(9 pt. B): 3050-3059.
  1. 23.   Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors
  2. Weiss, Jonathan; Davies, Luke C.; Karwan, Megan; Ileva, Lilia; Ozaki, Michelle K.; Cheng, Robert; Ridnour, Lisa; Annunziata, Christina M.; Wink, David; McVicar, Daniel
  3. Journal of Clinical Investigation. 2018, Aug 31; 128(9): 3794-3805.
  1. 24.   ONC201 kills breast cancer cells in vitro by targeting mitochondria
  2. Greer, Yoshimi Endo; Porat-Shliom, Natalie; Nagashima, Kunio; Stuelten, Christina; Crooks, Dan; Koparde, Vishal; Gilbert, Samuel F; Islam, Celia; Ubaldini, Ashley; Ji, Yun; Gattinoni, Luca; Soheilian, Ferri; Wang, Xiantao; Hafner, Markus; Shetty, Jyoti; Tran, Bao; Jailwala, Parthav; Cam, Maggie; Lang, Martin; Voeller, Donna; Reinhold, William C; Rajapakse, Vinodh; Pommier, Yves; Weigert, Roberto; Linehan, W Marston; Lipkowitz, Stanley
  3. Oncotarget. 2018, Apr 06; 9(26): 18454-18479.
  1. 25.   Transcription profiling suggests that mitochondrial topoisomerase IB acts as a topological barrier and regulator of mitochondrial DNA transcription
  2. Dalla Rosa, Ilaria; Zhang, Hongliang; Khiati, Salim; Wu, Xiaolin; Pommier, Yves
  3. Journal of Biological Chemistry. 2017, Dec 8; 292(49): 20162-20172.
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