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  1. 1.   RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity
  2. Castel, Pau; Dharmaiah,Sathiya; Sale, Matthew J; Messing,Simon; Rizzuto, Gabrielle; Cuevas-Navarro, Antonio; Cheng, Alice; Trnka, Michael J; Urisman, Anatoly; Esposito,Dom; Simanshu,Dhirendra; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2021, Aug 17; 118(33):
  1. 2.   FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland
  2. Isono, Yasuhiro; Furuya, Mitsuko; Kuwahara, Tatsu; Sano, Daisuke; Suzuki, Kae; Jikuya, Ryosuke; Mitome, Taku; Otake, Shinji; Kawahara, Takashi; Ito, Yusuke; Muraoka, Kentaro; Nakaigawa, Noboru; Kimura, Yayoi; Baba, Masaya; Nagahama, Kiyotaka; Takahata, Hiroyuki; Saito, Ichiro; Schmidt,Laura; Linehan, W Marston; Kodama, Tatsuhiko; Yao, Masahiro; Oridate, Nobuhiko; Hasumi, Hisashi
  3. Biochemical and biophysical research communications. 2020, FEB 19; 522(4): 931-938.
  1. 3.   The Metabolic Basis of Kidney Cancer
  2. Linehan, W. Marston; Schmidt,Laura; Crooks, Daniel R.; Wei, Darmood; Srinivasan, Ramaprasad; Lang, Martin; Ricketts, Christopher J.
  3. Cancer discovery. 2019, AUG; 9(8): 1006-1021.
  1. 4.   Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
  2. Bruning, Ulrike; Morales-Rodriguez, Francisco; Kalucka, Joanna; Goveia, Jermaine; Taverna, Federico; Queiroz, Karla C S; Dubois, Charlotte; Cantelmo, Anna Rita; Chen, Rongyuan; Loroch, Stefan; Timmerman, Evy; Caixeta, Vanessa; Bloch, Katarzyna; Conradi, Lena-Christin; Treps, Lucas; Staes, An; Gevaert, Kris; Tee, Andrew; Dewerchin, Mieke; Semenkovich, Clay F; Impens, Francis; Schilling, Birgit; Verdin, Eric; Swinnen, Johannes V; Meier, Jordan; Kulkarni, Rhushikesh A; Sickmann, Albert; Ghesquière, Bart; Schoonjans, Luc; Li, Xuri; Mazzone, Massimiliano; Carmeliet, Peter
  3. Cell Metabolism. 2018, Dec 4; 28(6): 866-880.e15.
  1. 5.   FLCN: The causative gene for Birt-Hogg-Dube syndrome
  2. Schmidt, Laura; Linehan, W. Marston
  3. GENE. 2018, Jan 15; 640: 28-42.
  1. 6.   mTORC1 senses stresses: Coupling stress to proteostasis
  2. Su, Kuo-Hui; Dai, Chengkai
  3. BIOESSAYS. 2017, May; 39(5): 1600268.
  1. 7.   MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
  2. Viola, G.; Bortolozzi, R.; Hamel, E.; Moro, S.; Brun, P.; Castagliuolo, I.; Ferlin, M. G.; Basso, G.
  3. Biochemical Pharmacology. 2012, Jan; 83(1): 16-26.
  1. 8.   Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization
  2. Hong, S. B.; Oh, H.; Valera, V. A.; Baba, M.; Schmidt, L. S.; Linehan, W. M.
  3. Plos One. 2010, Dec; 5(12): 12.
  1. 9.   Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling
  2. Hong, S. B.; Oh, H.; Valera, V. A.; Stull, J.; Ngo, D. T.; Baba, M.; Merino, M. J.; Linehan, W. M.; Schmidt, L. S.
  3. Molecular Cancer. 2010, Jun; 9: 13.
  1. 10.   Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
  2. Hasumi, Y.; Baba, M.; Ajima, R.; Hasumi, H.; Valera, V. A.; Klein, M. E.; Haines, D. C.; Merino, M. J.; Hong, S. B.; Yamaguchi, T. P.; Schmidt, L. S.; Linehan, W. M.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(44): 18722-18727.
  1. 11.   The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development
  2. Morrison, D. K.
  3. Trends in Cell Biology. 2009 19(1): 16-23.
  1. 12.   Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice
  2. Kim, H. W.; Park, I. K.; Cho, C. S.; Lee, K. H.; Beck, G. R.; Colburn, N. H.; Cho, M. H.
  3. Cancer Research. 2004, NOV 1; 64(21): 7971-7976.
  1. 13.   Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways
  2. Nagy, Z. S.; Wang, Y. L.; Erwin-Cohen, R. A.; Aradi, J.; Monia, B.; Wang, L. H.; Stepkowski, S. M.; Rui, H.; Kirken, R. A.
  3. Journal of Leukocyte Biology. 2002 72(4): 819-828.
  1. 14.   The Immunostimulative Effect and Mechanisms of a Novel Mouse Anti-Human PD-1 Monoclonal Antibody on Jurkat Lymphocytic Cells Cocultured with Hepatoma Cells
  2. Li, Ziwei; Li, Bin; Li, Li; Wang, Guanying; Li, Yuanyuan; Fu, Ruoqiu; Ming, Yue; Ni, Rui; Wang,Jiming; Ye, George; Chen, Jianhong
  3. OncoTargets and Therapy. 2020 13: 12225-12241.
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