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  1. 1.   Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
  2. Smith,Steven; Zhao,Xuezhi; Hughes,Stephen; Burke,Terrence
  3. Viruses. 2025, Jan 16; 17(1):
  1. 2.   A patient-derived cell model for malignant transformation in IDH-mutant glioma
  2. Kim, Olga; Sergi, Zach; Yu, Guangyang; Yamamoto, Kazutoshi; Quezado, Martha; Abdullaev, Zied; Crooks, Danel R; Kishimoto, Shun; Li, Qi; Lu, Peng; Blackman, Burchelle; Andresson,Thorkell; Wu,Xiaolin; Tran,Bao; Wei, Jun S; Zhang, Wei; Zhang, Meili; Song, Hua; Khan, Javed; Krishna, Murali C; Brender, Jeffrey R; Wu, Jing
  3. Acta Neuropathologica Communications. 2024, Sep 10; 12(1): 148.
  1. 3.   N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants
  2. Mahajan,Pankaj; Smith,Steven; Li, Min; Craigie, Robert; Hughes,Stephen; Zhao,Xuezhi; Burke,Terrence
  3. ACS Infectious Diseases. 2024, Feb 12;
  1. 4.   Attenuation of aggressive tumor progression of anaplastic thyroid cancer by p53
  2. Hwang, Eunmi; Kruhlak, Michael; Wong,Nathan; Chari,Raj; Kimura, Takahito; Cheng, Sheue-Yann
  3. American Journal of Cancer Research. 2024 14(9): 4429-4444.
  1. 5.   Target-Specific Nanoparticle Polyplex Down-Regulates Mutant Kras to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression
  2. Smith, Jill P; Chen, Wenqiang; Shivapurkar, Narayan; Gerber, Monica; Tucker, Robin D; Kallakury, Bhaskar; Dasa, Siva Sai Krishna; Kularatne,Ruvanthi Nilanga; Stern,Steve
  3. International Journal of Molecular Sciences. 2023, Jan 01; 24(1):
  1. 6.   Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates
  2. Trofka, Anna; Huang,Bau-Lin; Zhu,Jianjian; Heinz,Will; Magidson,Valentin; Shibata, Yuki; Shi, Yun-Bo; Tarchini, Basile; Stadler, H Scott; Kabangu, Mirindi; Al Haj Baddar, Nour W; Voss, S Randal; Mackem,Susan
  3. Current biology : CB. 2021, Nov 22; 31(22): 4923-4934.e5.
  1. 7.   HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants
  2. Smith,Steven; Zhao,Xue Zhi; Passos, Dario Oliveira; Pye, Valerie E.; Cherepanov, Peter; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. ACS Infectious Diseases. 2021, Jun 11; 7(6): 1469-1482.
  1. 8.   The metabolic landscape of RAS-driven cancers from biology to therapy
  2. Mukhopadhyay,Suman; Vander Heiden, Matthew G.; McCormick, Frank
  3. Nature Cancer. 2021, Mar; 2(3): 271-283.
  1. 9.   Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
  2. Kharat,Suhas; Ding, Xia; Swaminathan, Divya; Suresh, Akshey; Singh, Manish; Sengodan,Satheesh; Burkett,Sandra; Marks, Hanna; Pamala, Chinmayi; He,Yafeng; Fox,Stephen; Buehler, Eugen C; Muegge,Kathrin; Martin, Scott E; Sharan,Shyam
  3. Science signaling. 2020, Aug 18; 13(645): pii: eaba8091.
  1. 10.   Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sI(AHP), and its potentiation in hippocampal pyramidal neurons
  2. Tedoldi, Angelo; Ludwig, Petra; Fulgenzi,Gianluca; Takeshima, Hiroshi; Pedarzani, Paola; Stocker, Martin
  3. PLOS ONE. 2020, JUN 19; 15(7):
  1. 11.   Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases
  2. Kondo, Yasushi; Ognjenovic,Jana; Banerjee, Saikat; Karandur, Deepti; Merk,Alan; Kulhanek, Kayla; Wong, Kathryn; Roose, Jeroen P.; Subramaniam, Sriram; Kuriyan, John
  3. SCIENCE. 2019, OCT 4; 366(6461): 109-+.
  1. 12.   Progress in targeting RAS with small molecule drugs
  2. McCormick, Frank
  3. The Biochemical journal. 2019, MAR 31; 476(2): 365-374.
  1. 13.   High-Mannose But Not Complex-Type Glycosylation of Tetherin Is Required for Restriction of HIV-1 Release
  2. Waheed, Abdul; Gitzen, Ariana; Swiderski, Maya; Freed, Eric
  3. Viruses. 2018, Jan 05; 10(1): E26.
  1. 14.   Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors
  2. Zhao, Xue Zhi; Smith, Steven; Maskell, Daniel P.; Metifiot, Mathieu; Pye, Valerie E.; Fesen, Katherine; Marchand, Christophe; Pommier, Yves; Cherepanov, Peter; Hughes, Stephen; Burke, Terrence
  3. Journal of Medicinal Chemistry. 2017, SEP 14; 60(17): 7315-7332.
  1. 15.   TrkA in vivo function is negatively regulated by ubiquitination
  2. Kiris, E.; Wang, T.; Yanpallewar, S.; Dorsey, S. G.; Becker, J.; Bavari, S.; Palko, M. E.; Coppola, V.; Tessarollo, L.
  3. Journal of Neuroscience. 2014, 12-Mar; 34(11): 4090-8.
  1. 16.   Scram1 is a modifier of spinal cord resistance for astrocytoma on mouse Chr 5
  2. Amlin-Van Schaick, J.; Kim, S.; Broman, K. W.; Reilly, K. M.
  3. Mammalian Genome. 2012, Apr; 23(3-4): 277-285.
  1. 17.   Advances in using PARP inhibitors to treat cancer
  2. Kummar, S.; Chen, A.; Parchment, R. E.; Kinders, R. J.; Ji, J.; Tomaszewski, J. E.; Doroshow, J. H.
  3. Bmc Medicine. 2012, Mar; 10
  1. 18.   A Structural Basis for Reversible Photoswitching of Absorbance Spectra in Red Fluorescent Protein rsTagRFP
  2. Pletnev, S.; Subach, F. V.; Dauter, Z.; Wlodawer, A.; Verkhusha, V. V.
  3. Journal of Molecular Biology. 2012, Mar; 417(3): 144-151.
  1. 19.   MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir
  2. Metifiot, M.; Johnson, B.; Smith, S.; Zhao, X. Z.; March, C.; Burke, T.; Hughes, S.; Pommier, Y.
  3. Antimicrobial Agents and Chemotherapy. 2011, Nov; 55(11): 5127-5133.
  1. 20.   A set of aspartyl protease-deficient strains for improved expression of heterologous proteins in Kluyveromyces lactis
  2. Ganatra, M. B.; Vainauskas, S.; Hong, J. M.; Taylor, T. E.; Denson, J. P. M.; Esposito, D.; Read, J. D.; Schmeisser, H.; Zoon, K. C.; Hartley, J. L.; Taron, C. H.
  3. Fems Yeast Research. 2011, Mar; 11(2): 168-178.
  1. 21.   The p53 Inhibitor MDM2 Facilitates Sonic Hedgehog-Mediated Tumorigenesis and Influences Cerebellar Foliation
  2. Malek, R.; Matta, J.; Taylor, N.; Perry, M. E.; Mendrysa, S. M.
  3. Plos One. 2011, Mar; 6(3): 13.
  1. 22.   Probing Cellular Processes with Oligo-Mediated Recombination and Using the Knowledge Gained to Optimize Recombineering
  2. Sawitzke, J. A.; Costantino, N.; Li, X. T.; Thomason, L. C.; Bubunenko, M.; Court, C.; Court, D. L.
  3. Journal of Molecular Biology. 2011, Mar; 407(1): 45-59.
  1. 23.   Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication
  2. Abram, M. E.; Ferris, A. L.; Shao, W.; Alvord, W. G.; Hughes, S. H.
  3. Journal of Virology. 2010, Oct; 84(19): 9864-9878.
  1. 24.   MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
  2. Salcedo, R.; Worschech, A.; Cardone, M.; Jones, Y.; Gyulai, Z.; Dai, R. M.; Wang, E. N.; Ma, W.; Haines, D.; O'HUigin, C.; Marincola, F. M.; Trinchieri, G.
  3. Journal of Experimental Medicine. 2010, Aug 2; 207(8): 1625-1636.
  1. 25.   Functional analysis of human BRCA2 variants using a mouse embryonic stem cell-based assay
  2. Kuznetsov, S. G.; Chang, S.; Sharan, S. K.
  3. Methods in molecular biology (Clifton, N.J.). 2010 653: 259-80.
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