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  1. 1.   Simple monocyclic pyrimidine analogs as microtubule targeting agents binding to the colchicine site
  2. Choudhary, Shruti; Kaku, Krishna; Robles, Andrew J; Hamel,Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry. 2023, Feb 24; 82: 117217.
  1. 2.   Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents
  2. Islam, Farhana; Doshi, Arpit; Robles, Andrew J; Quadery, Tasdique M; Zhang, Xin; Zhou, Xilin; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Molecules . 2022, Jan 05; 27(1):
  1. 3.   Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure-activity relationship, in vitro and in vivo evaluation as antitumor agents
  2. Islam, Farhana; Quadery, Tasdique M.; Bai,Ruoli; Luckett-Chastain, Lerin R.; Hamel,Ernest; Ihnat, Michael A.; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry Letters. 2021, Jun 1; 41
  1. 4.   Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer
  2. Choudhary, Shruti; Doshi, Arpit; Luckett-Chastain, Lerin; Ihnat, Michael; Hamel,Ernest; Mooberry, Susan L.; Gangjee, Aleem
  3. Bioogranic & Medicinal Chemistry. 2021, Apr 1; 35
  1. 5.   The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity
  2. Xiang, Weiguo; Quadery, Tasdique M; Hamel,Ernest; Luckett-Chastain, Lerin R; Ihnat, Michael A; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & medicinal chemistry. 2021, Jan 1; 29: 115887.
  1. 6.   Sterically induced conformational restriction: Discovery and preclinical evaluation of novel pyrrolo[3,2-d]pyrimidines as microtubule targeting agents
  2. Pavana, Roheeth Kumar; Shah, Khushbu; Gentile, Taylor; Dybdal-Hargreaves, Nicholas F.; Risinger, April L.; Mooberry, Susan L.; Hamel, Ernest; Gangjee, Aleem
  3. BIOORGANIC & MEDICINAL CHEMISTRY. 2018, NOV 1; 26(20): 5470-5478.
  1. 7.   Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
  2. Xiang, Weiguo; Choudhary, Shruti; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry. 2018, May 15; 26(9): 2437-2451.
  1. 8.   Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo [3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple -acting angiokinase inhibition as antitumor agents
  2. Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A.; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem
  3. BIOORGANIC & MEDICINAL CHEMISTRY. 2017, Jan 15; 25(2): 545-556.
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