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  1. 1.   Identification of molecular determinants of gene-specific bursting patterns by high-throughput imaging screens
  2. Sood, Varun; Holewinski,Ronald; Andresson,Thorkell; Larson, Daniel R; Misteli, Tom
  3. Molecular Cell. 2025, Feb 11;
  1. 2.   CD163+ Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma
  2. Mori, Masayuki; Sakamoto, Atsushi; Kawakami, Rika; Guo, Liang; Slenders, Lotte; Mosquera, Jose Verdezoto; Ghosh, Saikat Kumar B; Wesseling, Marian; Shiraki, Tatsuya; Bellissard, Arielle; Shah, Palak; Weinkauf, Craig C; Konishi, Takao; Sato, Yu; Cornelissen, Anne; Kawai, Kenji; Jinnouchi, Hiroyuki; Xu, Weili; Vozenilek, Aimee E; Williams, Desiree; Tanaka, Takamasa; Sekimoto, Teruo; Kelly,Michael; Fernandez, Raquel; Grogan, Alyssa; Coslet, A J; Fedotova, Alisa; Kurse, Anjali; Mokry, Michal; Romero, Maria E; Kolodgie, Frank D; Pasterkamp, Gerard; Miller, Clint L; Virmani, Renu; Finn, Aloke V
  3. Circulation Research. 2024, Jul 5; 135(2): e4-e23.
  1. 3.   Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR
  2. Sharma,Alok; Pei, Jun; Yang, Yue; Dyba,Marcin; Smith,Brian; Rabara,Dana; Larsen,Erik; Lightstone, Felice C; Esposito,Dom; Stephen,Andy; Wang, Bin; Beltran, Pedro J; Wallace, Eli; Nissley,Dwight; McCormick, Frank; Maciag,Anna
  3. The Journal of Biological Chemistry. 2024, Jan 16; 300(2): 105650.
  1. 4.   Investigating the NRAS 5' UTR as a target for small molecules
  2. Balaratnam,Sumirtha; Torrey, Zachary R; Calabrese,Dave; Banco, Michael T; Yazdani, Kamyar; Liang, Xiao; Fullenkamp,Chris; Seshadri,Sri; Holewinski,Ronald; Andresson,Thorkell; Ferré-D'Amaré, Adrian R; Incarnato, Danny; Schneekloth,Jay
  3. Cell Chemical Biology. 2023, Jun 15; 30(6): 643-657.e8.
  1. 5.   Machine Learning Informs RNA-Binding Chemical Space
  2. Yazdani, Kamyar; Jordan, Deondre; Yang,Mo; Fullenkamp,Chris; Schneekloth,Jay; Calabrese,Dave; Boer, Robert E; Hilimire, Thomas A; Allen, Timothy E H; Khan, Rabia T
  3. Angewandte Chemie (International ed. in English). 2022, Dec 30;
  1. 6.   Structural insights of the conserved "priming loop" of hepatitis B virus pre-genomic RNA
  2. LeBlanc, Regan M; Kasprzak,Wojciech; Longhini, Andrew P; Olenginski, Lukasz T; Abulwerdi, Fardokht; Ginocchio, Stefano; Shields, Brigit; Nyman, Julie; Svirydava, Maryia; Del Vecchio, Claudia; Ivanic,Joseph; Schneekloth,Jay; Shapiro, Bruce A; Dayie, Theodore Kwaku; Le Grice,Stuart
  3. Journal of Biomolecular Structure & Dynamics. 2022, Jun 22; 40(20): 9761-9773.
  1. 7.   Adcitmer(R), a new CD56-targeting monomethyl auristatin E-conjugated antibody, is a potential therapeutic approach in Merkel cell carcinoma
  2. Esnault, C.; Martin, C.; Desgranges, A.; Baltus, C. B.; Aubrey, N.; Lakhrif, Z.; Lajoie, L.; Lantier, L.; Clemenceau, B.; Sarma, B.; Schrama, J.; Houben, R.; Schrama, D.; Hesbacher, S.; Feng,Yang; Dimitrov, D.; Guyetant, S.; Berthon, P.; Viaud-Massuard, M. C.; Samimi, M.; Touze, A.; Kervarrec, T.
  3. The British Journal of Dermatology. 2021, Sep 28;
  1. 8.   Arrow pushing in RNA modification sequencing
  2. Bartee,David; Thalalla Gamage,Supuni; Link,Courtney; Meier,Jordan
  3. Chemical Society reviews. 2021, Jul 14;
  1. 9.   CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
  2. Shrestha, Roshan L.; Rossi, Austin; Wangsa, Darawalee; Hogan, Ann K.; Zaldana, Kimberly S.; Suva, Evelyn; Chung, Yang Jo; Sanders,Chelsea; Difilippantonio,Simone; Karpova, Tatiana S.; Karim,Baktiar; Foltz, Daniel R.; Fachinetti, Daniele; Aplan, Peter D.; Ried, Thomas; Basrai, Munira A.
  3. The Journal of Cell Biology. 2021, Feb 23; 220(4):
  1. 10.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 11.   Three-Color Imaging Enables Simultaneous Screening of Multiple RNA Targets on Small Molecule Microarrays
  2. Jordan,Deondre; Yang,Mo; Schneekloth,Jay
  3. Current protocols in chemical biology. 2020, Dec; 12(4): e87.
  1. 12.   Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design
  2. Tran, Brandon; Pichling, Patricio; Tenney, Logan; Connelly, Colleen M; Moon, Michelle H; Ferré-D'Amaré, Adrian R; Schneekloth,Jay; Jones, Christopher P
  3. Cell chemical biology. 2020, OCT 15; 27(10): 1241-+.
  1. 13.   The LTB4-BLT1 axis regulates actomyosin and beta(2)-integrin dynamics during neutrophil extravasation
  2. Subramanian, Bhagawat C.; Melis, Nicolas; Chen, Desu; Wang, Weiye; Gallardo,Devorah; Weigert, Roberto; Parent, Carole A.
  3. JOURNAL OF CELL BIOLOGY. 2020, OCT 5; 219(10):
  1. 14.   SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations
  2. Liao, Tsung-Jen; Jang,Hyunbum; Fushman, David; Nussinov,Ruth
  3. The Journal of chemical physics. 2020, Jul 28; 153(4): 045106.
  1. 15.   Creating and screening natural product libraries
  2. Wilson,Brice; Thornburg,Chris; Henrich,Curtis; Grkovic,Tanja; O'Keefe,Barry
  3. Natural product reports. 2020, JUL 1; 37: 893-918.
  1. 16.   Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer
  2. Zeligs, Kristen P.; Morelli, Maria Pia; David, Justin M.; Neuman, Monica; Hernandez, Lidia; Hewitt, Stephen; Ozaki, Michelle; Osei-Tutu, Akosua; Anderson, David; Andresson,Thorkell; Das,Sudipto; Lack,Justin; Abdelmaksoud,Abdalla; Fantini, Massimo; Arlen, Philip M.; Tsang, Kwong Y.; Annunziata, Christina M.
  3. FRONTIERS IN ONCOLOGY. 2020, JUN 19; 10: 805.
  1. 17.   Allosteric p97 inhibitors can overcome resistance to ATP-competitive p97 inhibitors for potential anti-cancer therapy
  2. Wang, Feng; Li, Shan; Gan, Taiping; Stott,Gordon; Flint,Andrew; Chou, Tsui-Fen
  3. ChemMedChem. 2020, APR 20; 15(8): 685-694.
  1. 18.   Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems
  2. Boer, Robert E.; Torrey, Zachary R.; Schneekloth,Jay
  3. ACS CHEMICAL BIOLOGY. 2020, Apr 17; 15(4): 808-818.
  1. 19.   High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1
  2. Liao,Tsung-Jen; Jang,Hyunbum; Nussinov,Ruth; Fushman, David
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2020, Feb 19; 142: 3401-3411.
  1. 20.   Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM
  2. Wäldchen, Felix; Schlegel, Jan; Götz, Ralph; Luciano,Michael; Schnermann,Martin; Doose, Sören; Sauer, Markus
  3. Nature communications. 2020, Feb 14; 11(1): pii:10.1038/s41467-020-14731-0.
  1. 21.   Specific RITA modification produces hyperselective cytotoxicity while maintaining in vivo antitumor efficacy
  2. Peyser,Brian; Hermone,Ann; Salamoun, Joseph M; Burnett, James C; Hollingshead,Melinda; McGrath,Connor; Gussio,Rick; Wipf, Peter
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1765-1774.
  1. 22.   Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility
  2. Stavreva, Diana A; Garcia, David A; Fettweis, Gregory; Gudla, Prabhakar R; Zaki,George; Soni, Vikas; McGowan, Andrew; Williams, Geneva; Huynh, Anh; Palangat, Murali; Schiltz, R Louis; Johnson, Thomas A; Presman, Diego M; Ferguson, Matthew L; Pegoraro, Gianluca; Upadhyaya, Arpita; Hager, Gordon L
  3. Molecular cell. 2019, SEP 19; 75(6): 1161-+.
  1. 23.   Using SHAPE-MaP to probe small molecule-RNA interactions
  2. Martin, Sarah; Blankenship, Carson; Rausch,Jason; Sztuba-Solinska, Joanna
  3. Methods (San Diego, Calif.). 2019, SEP 1; 167: 105-116.
  1. 24.   Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder
  2. Donohue, Elizabeth; Khorsand, Sina; Mercado, Gabriel; Varney, Kristen M; Wilder, Paul T; Yu, Wenbo; MacKerell, Alexander D; Alexander,Patrick; Van,Que; Moree, Ben; Stephen,Andy; Weber, David J; Salafsky, Joshua; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, Aug 27; 116(35): 17290-17297.
  1. 25.   The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X
  2. Song, He; Ji,Xinhua
  3. NATURE COMMUNICATIONS. 2019, Jul 12; 10(1):
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