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  1. 1.   K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins
  2. Magits, Wout; Steklov, Mikhail; Jang,Hyunbum; Sewduth, Raj N; Florentin, Amir; Lechat, Benoit; Sheryazdanova, Aidana; Zhang, Mingzhen; Simicek, Michal; Prag, Gali; Nussinov,Ruth; Sablina, Anna
  3. The EMBO Journal. 2024, Jun 10;
  1. 2.   Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
  2. Zhang, Xiyuan; Lou, Hannah E; Gopalan, Vishaka; Liu, Zhihui; Jafarah, Hilda M; Lei, Haiyan; Jones, Paige; Sayers, Carly M; Yohe, Marielle E; Chittiboina, Prashant; Widemann, Brigitte C; Thiele, Carol J; Kelly,Michael; Hannenhalli, Sridhar; Shern, Jack F
  3. Cell Reports. 2022, Sep 20; 40(12): 111363.
  1. 3.   ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
  2. Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Merna Timaul, Neilawattie; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M; Jänne, Pasi A; McCormick, Frank; Yao, Zhan; Rosen, Neal
  3. Molecular Cell. 2022, May 14;
  1. 4.   Verbal learning and memory in youth with neurofibromatosis type 1 and plexiform neurofibromas: Relationships with disease severity
  2. Loucas, Caitlyn; Wolters, Pamela; Tamula,Mary Anne; Rhodes, Amanda; Baldwin,Andrea; Goodwin, Anne; Widemann, Brigitte; Martin, Staci
  3. European Journal of Paediatric Neurology : EJPN : official journal of the European Paediatric Neurology Society. 2022, Mar 13; 38: 7-12.
  1. 5.   Adolescents and young adults with neurofibromatosis type 1: A descriptive study of adaptive functioning
  2. Struemph,Kari; Watts, Adreanna T M; Wolters, Pamela L; Tamula,Mary Anne; Baldwin,Andrea; Widemann, Brigitte; Martin, Staci
  3. American Journal of Medical Genetics Part A. 2021, Nov 03;
  1. 6.   Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR
  2. Yan,Wupeng; Markegard, Evan; Dharmaiah, Srisathiyanarayanan; Urisman, Anatoly; Drew, Matthew; Esposito,Dom; Scheffzek, Klaus; Nissley,Dwight; McCormick, Frank; Simanshu,Dhirendra
  3. Cell reports. 2020, Jul 21; 32(3): 107909.
  1. 7.   Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer
  2. Sherekar,Mukul; Han, Sae-Won; Ghirlando, Rodolfo; Messing,Simon; Drew,Matt; Rabara,Dana; Waybright,Tim; Juneja, Puneet; O'Neill, Hugh; Stanley, Christopher B; Bhowmik, Debsindhu; Ramanathan, Arvind; Subramaniam,Sriram; Nissley,Dwight; Gillette,Bill; McCormick, Frank; Esposito,Dom
  3. The Journal of biological chemistry. 2020, JAN 24; 295(4): 1105-1119.
  1. 8.   KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis
  2. Rabara,Dana; Tran,Tim; Dharmaiah,Sathiya; Stephens,Bob; McCormick, Frank; Simanshu,Dhirendra; Holderfield, Matthew
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, OCT 29; 116(44): 22122-22131.
  1. 9.   Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies
  2. Gursel, D. B.; Connell-Albert, Y. S.; Tuskan, R. G.; Anastassiadis, T.; Walrath, J. C.; Hawes, J. J.; Amlin-Van Schaick, J. C.; Reilly, K. M.
  3. Neuro-Oncology. 2011, Jun; 13(6): 610-621.
  1. 10.   Back to the Future: Proceedings From the 2010 NF Conference
  2. Huson, S. M.; Acosta, M. T.; Belzberg, A. J.; Bernards, A.; Chernoff, J.; Cichowski, K.; Evans, D. G.; Ferner, R. E.; Giovannini, M.; Korf, B. R.; Listernick, R.; North, K. N.; Packer, R. J.; Parada, L. F.; Peltonen, J.; Ramesh, V.; Reilly, K. M.; Risner, J. W.; Schorry, E. K.; Upadhyaya, M.; Viskochil, D. H.; Zhu, Y. A.; Hunter-Schaedle, K.; Giancotti, F. G.
  3. American Journal of Medical Genetics Part A. 2011, Feb; 155A(2): 307-321.
  1. 11.   Schweinfurthin A Selectively Inhibits Proliferation and Rho Signaling in Glioma and Neurofibromatosis Type 1 Tumor Cells in a NF1-GRD-Dependent Manner
  2. Turbyville, T. J.; Gursel, D. B.; Tuskan, R. G.; Walrath, J. C.; Lipschultz, C. A.; Lockett, S. J.; Wiemer, D. F.; Beutler, J. A.; Reilly, K. M.
  3. Molecular Cancer Therapeutics. 2010, May; 9(5): 1234-1243.
  1. 12.   Evidence of perturbations of cell cycle and DNA repair pathways as a consequence of human and murine NF1-haploinsufficiency
  2. Pemov, A.; Park, C.; Reilly, K. M.; Stewart, D. R.
  3. Bmc Genomics. 2010, Mar; 11: 16.
  1. 13.   The Neurofibromatosis Type 1 Tumor Suppressor Controls Cell Growth by Regulating Signal Transducer and Activator of Transcription-3 Activity In vitro and In vivo
  2. Banerjee, S.; Byrd, J. N.; Gianino, S. M.; Harpstrite, S. E.; Rodriguez, F. J.; Tuskan, R. G.; Reilly, K. M.; Piwnica-Worms, D. R.; Gutmann, D. H.
  3. Cancer Research. 2010, Feb; 70(4): 1356-1366.
  1. 14.   Bioluminescent Approaches for Measuring Tumor Growth in a Mouse Model of Neurofibromatosis
  2. Hawes, J. J.; Reilly, K. M.
  3. Toxicologic Pathology. 2010, Jan; 38(1): 123-130.
  1. 15.   Neurofibromatosis and lessons for the war on cancer
  2. Reilly, K. M.
  3. Embo Molecular Medicine. 2009, Jul; 1(4): 198-200.
  1. 16.   Chr 19(A/J) modifies tumor resistance in a sex- and parent-of-origin-specific manner
  2. Walrath, J. C.; Fox, K.; Truffer, E.; Alvord, W. G.; Quinones, O. A.; Reilly, K. M.
  3. Mammalian Genome. 2009 20(4): 214-223.
  1. 17.   Rethinking brain tumors: The fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop
  2. Reilly, K. M.; Rubin, J. B.; Gilbertson, R. J.; Garbow, J. R.; Roussel, M. F.; Gutmann, D. H.
  3. Cancer Research. 2008 68(14): 5508-5511.
  1. 18.   Real-time PCR analysis of candidate imprinted genes on mouse chromosome 11 shows balanced expression from the maternal and paternal chromosomes and strain-specific variation in expression levels
  2. Tuskan, R. G.; Tsang, S.; Sun, Z. H.; Baer, J.; Rozenblum, E.; Wu, X. L.; Munroe, D. J.; Reilly, K. M.
  3. Epigenetics. 2008 3(1): 43-50.
  1. 19.   Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies
  2. Hawes, J. J.; Tuskan, R. G.; Reilly, K. M.
  3. Neurogenetics. 2007, Apr; 8(2): 121-130.
  1. 20.   An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model
  2. Reilly, K. M.; Broman, K. W.; Bronson, R. T.; Tsang, S.; Loisel, D. A.; Christy, E. S.; Sun, Z. H.; Diehl, J.; Munroe, D. J.; Tuskan, R. G.
  3. Cancer Research. 2006, JAN 1; 66(1): 62-68.
  1. 21.   New approaches to the analysis of palindromic sequences from the human genome: evolution and polymorphism of an intronic site at the NF1 locus
  2. Lewis, S. M.; Chen, S. A.; Strathern, J. N.; Rattray, A. J.
  3. Nucleic Acids Research. 2005 33(22, Art. No. e186):
  1. 22.   The importance of genome architecture in cancer susceptibility - Location, location, location
  2. Reilly, K. M.
  3. Cell Cycle. 2004, NOV; 3(11): 1378-1382.
  1. 23.   Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects
  2. Reilly, K. M.; Tuskan, R. G.; Christy, E.; Loisel, D. A.; Ledger, J.; Bronson, R. T.; Smith, C. D.; Tsang, S.; Munroe, D. J.; Jacks, T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2004, AUG 31; 101(35): 13008-13013.
  1. 24.   Comparative pathology of nerve sheath tumors in mouse models and humans
  2. Stemmer-Rachamimov, A. O.; Louis, D. N.; Nielsen, G. P.; Antonescu, C. R.; Borowsky, A. D.; Bronson, R. T.; Burns, D. K.; Cervera, P.; McLaughlin, M. E.; Reifenberger, G.; Schmale, M. C.; MacCollin, M.; Chao, R. C.; Cichowski, K.; Kalamarides, M.; Messerli, S. M.; McClatchey, A. I.; Niwa-Kawakita, M.; Ratner, N.; Reilly, K. M.; Zhu, Y.; Giovannini, M.
  3. Cancer Research. 2004 64(10): 3718-3724.
  1. 25.   Measurement of KRAS-GTPase Activity
  2. Rabara,Dana; Stephen,Andy
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2797: 91-102.
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