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  1. 1.   Utilization of achiral alkenyl amines for the preparation of high affinity Grb2 SH2 domain-binding macrocycles by ring-closing metathesis
  2. Liu, F.; Worthy, K. M.; Bindu, L.; Giubellino, A.; Bottaro, D. P.; Fisher, R. J.; Burke, T. R.
  3. Organic & Biomolecular Chemistry. 2007 5(2): 367-372.
  1. 2.   Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity
  2. Shi, Z. D.; Liu, H. P.; Zhang, M. C.; Worthy, K. M.; Bindu, L.; Yang, D. J.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry. 2005, JUL 1; 13(13): 4200-4208.
  1. 3.   Examination of phosphoryl-mimicking functionalities within a macrocyclic Grb2 SH2 domain-binding platform
  2. Kang, S. U.; Shi, Z. D.; Worthy, K. M.; Bindu, L. K.; Dharmawardana, P. G.; Choyke, S. J.; Bottaro, D. P.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2005, JUN 16; 48(12): 3945-3948.
  1. 4.   Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles
  2. Oishi, S.; Shi, Z. D.; Worthy, K. M.; Bindu, L. K.; Fisher, R. J.; Burke, T. R.
  3. Chembiochem. 2005, APR; 6(4): 668-674.
  1. 5.   Synthesis of a 5-methylindolyl-containing macrocycle that displays ultrapotent Grb2 SH2 domain-binding affinity
  2. Shi, Z. D.; Lee, K.; Wei, C. Q.; Roberts, L. R.; Worthy, K. M.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2004 47(4): 788-791.
  1. 6.   Enantioselective synthesis of metathesis-derived ureapeptoid macrocycles
  2. Wang, X. Z.; Burke, T. R.
  3. Synlett. 2004 (3): 469-472.
  1. 7.   Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems
  2. Wei, C. Q.; Gao, Y.; Lee, K.; Guo, R.; Li, B. H.; Zhang, M. C.; Yang, D. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2003 46(2): 244-254.
  1. 8.   Designed Epothilones - Combinatorial Synthesis, Tubulin Assembly Properties, and Cytotoxic Action Against Taxol-Resistant Tumor Cells
  2. Nicolaou, K. C.; Vourloumis, D.; Li, T. H.; Pastor, J.; Winssinger, N.; He, Y.; Ninkovic, S.; Sarabia, F.; Vallberg, H.; Roschangar, F.; King, N. P.; Finlay, M. R. V.; Giannakakou, P.; Verdierpinard, P.; Hamel, E.
  3. Angewandte Chemie-International Edition. 1997 36(19): 2097-2103.
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