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  1. 1.   Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
  2. Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu,Xia; Andresson,Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer,Thomas; Hartmann, Oliver; Diefenbacher, Markus E; Pommier, Yves; Weyemi, Urbain
  3. Molecular Carcinogenesis. 2024, Feb 27;
  1. 2.   A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer
  2. Manzo, Julia; Puhalla, Shannon; Pahuja, Shalu; Ding, Fei; Lin, Yan; Appleman, Leonard; Tawbi, Hussein; Stoller, Ronald; Lee, James J; Diergaarde, Brenda; Kiesel, Brian F; Yu, Jing; Tan, Antoinette R; Belani, Chandra P; Chew, Helen; Garcia, Agustin A; Morgan, Robert J; Wahner Hendrickson, Andrea E; Visscher, Daniel W; Hurley, Rachel M; Kaufmann, Scott H; Swisher, Elizabeth M; Oesterreich, Steffi; Katz, Tiffany; Ji,Jay; Zhang, Yiping; Parchment, Ralph E; Chen, Alice; Duan, Wenrui; Giranda, Vincent; Shepherd, Stacie P; Ivy, S Percy; Chu, Edward; Beumer, Jan H
  3. Cancer Chemotherapy and Pharmacology. 2022, Apr 18; 89(5): 721-735.
  1. 3.   Exploring role of 5hmC as potential marker of chemoresistance
  2. Kharat,Suhas; Sharan,Shyam
  3. MOLECULAR & CELLULAR ONCOLOGY. 2020, Oct 22; 7(6): 1827904.
  1. 4.   PARP Inhibitor Sensitivity Does Not Depend on BAP1 but Is Enhanced by Temozolomide in MGMT Deficient Human Mesothelioma Cells
  2. Rathkey, D.; Khanal, M.; Murai, J.; Zhang, J.; Jiang, Q.; Morrow, B.; Evans, C.; Chari,Raj; Sengupta, M.; Thomas, A.; Pommier, Y.; Hassan, R.
  3. JOURNAL OF THORACIC ONCOLOGY. 2019, OCT; 14(10): S296-S296.
  1. 5.   Durvalumab in Combination with Olaparib in Patients with Relapsed Small Cell Lung Cancer: Results from a Phase II Study
  2. Thomas, Anish; Vilimas, Rasa; Trindade, Christopher; Erwin-Cohen,Rebecca; Roper, Nitin; Xi, Liqiang; Krishnasamy, Venkatesh; Levy, Elliot; Mammen, Andy; Nichols, Samantha; Chen, Yuanbin; Velcheti, Vamsidhar; Yin, Faye; Szabo, Eva; Pommier, Yves; Steinberg, Seth M; Trepel, Jane B; Raffeld, Mark; Young,Howard; Khan, Javed; Hewitt, Stephen; Lee, Jung-Min
  3. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2019, AUG; 14(8): 1447-1457.
  1. 6.   A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1-3 inhibitor, cediranib, in recurrent women's cancers with biomarker analyses
  2. Zimmer, Alexandra S; Nichols,Erin; Cimino-Mathews, Ashley; Peer, Cody; Cao, Liang; Lee, Min-Jung; Kohn, Elise C; Annunziata, Christina M; Lipkowitz, Stanley; Trepel, Jane B; Sharma, Rajni; Mikkilineni, Lekha; Gatti-Mays, Margaret; Figg, William D; Houston, Nicole D; Lee, Jung-Min
  3. Journal for immunotherapy of cancer. 2019, Jul 25; 7(1): 197.
  1. 7.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 8.   Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations
  2. Karzai, Fatima; VanderWeele, David; Madan, Ravi A; Owens, Helen; Cordes, Lisa M; Hankin, Amy; Couvillon, Anna; Nichols, Erin; Bilusic, Marijo; Beshiri, Michael L; Kelly, Kathleen; Krishnasamy, Venkatesh; Lee, Sunmin; Lee, Min-Jung; Yuno, Akira; Trepel, Jane B; Merino, Maria J; Dittamore, Ryan; Marté, Jennifer; Donahue, Renee N; Schlom, Jeffrey; Killian, Keith J; Meltzer, Paul S; Steinberg, Seth M; Gulley, James L; Lee, Jung-Min; Dahut, William L
  3. Journal for immunotherapy of cancer. 2018, Dec 04; 6(1): 141.
  1. 9.   RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
  2. Dungrawala, Huzefa; Bhat, Kamakoti P; Le Meur, Rémy; Chazin, Walter J; Ding, Xia; Sharan, Shyam; Wessel, Sarah R; Sathe, Aditya A; Zhao, Runxiang; Cortez, David
  3. Molecular cell. 2017, Aug 3; 67(3): 374-+.
  1. 10.   Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types
  2. Niu, Jing; Scheuerell, Christie; Mehrotra, Shailly; Karan, Sharon; Puhalla, Shannon; Kiesel, Brian F; Ji, Jay; Chu, Edward; Gopalakrishnan, Mathangi; Ivaturi, Vijay; Gobburu, Jogarao; Beumer, Jan H
  3. Journal of clinical pharmacology. 2017, Aug; 57(8): 977-987.
  1. 11.   Liquid Chromatographic Determination of NSC 737664 (ABT-888: An Inhibitor of Poly(ADP-ribose) Polymerase (PARP)) in Plasma and Urine in a Phase 0 Clinical Trial
  2. Phillips, L. R.; Hill, K. D.; Majerova, E.
  3. Journal of Liquid Chromatography & Related Technologies. 2009 32(2): 261-272.
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