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  1. 1.   Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs
  2. LeBlanc, Amy K.; Mazcko, Christina N.; Cherukuri, Aswini; Berger,Erika; Kisseberth, William C.; Brown, Megan E.; Lana, Susan E.; Weishaar, Kristen; Flesner, Brian K.; Bryan, Jeffrey N.; Vail, David M.; Burton, Jenna H.; Willcox, Jennifer L.; Mutsaers, Anthony J.; Woods, J. Paul; Northrup, Nicole C.; Saba, Corey; Curran, Kaitlin M.; Leeper, Haley; Wilson-Robles, Heather; Wustefeld-Janssens, Brandan G.; Lindley, Stephanie; Smith, Annette N.; Dervisis, Nikolaos; Klahn, Shawna; Higginbotham, Mary Lynn; Wouda, Raelene M.; Krick, Erika; Mahoney, Jennifer A.; London, Cheryl A.; Barber, Lisa G.; Balkman, Cheryl E.; McCleary-Wheeler, Angela L.; Suter, Steven E.; Martin, Olya; Borgatti, Antonella; Burgess, Kristine; Childress, Michael O.; Fidel, Janean L.; Allstadt, Sara D.; Gustafson, Daniel L.; Selmic, Laura E.; Khanna, Chand; Fan, Timothy M.
  3. CLINICAL CANCER RESEARCH. 2021, Jun 1; 27: 3005-3016.
  1. 2.   Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis
  2. Xie, Yingda L.; de Jager, Veronique R.; Chen, Ray Y.; Dodd, Lori E.; Paripati, Praveen; Via, Laura E.; Follmann, Dean; Wang,Jing; Lumbard, Keith; Lahouar, Saher; Malherbe, Stephanus T.; Andrews, Jenna; Yu, Xiang; Goldfeder, Lisa C.; Cai, Ying; Arora, Kriti; Loxton, Andre G.; Vanker, Naadira; Duvenhage,Michael; Winter, Jill; Song, Taeksun; Walzl, Gerhard; Diacon, Andreas H.; Barry, Clifton E.
  3. Science Translational Medicine. 2021, Feb 3; 13(579):
  1. 3.   Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma
  2. Kowalczyk, Joshua T.; Wan, Xiaolin; Hernandez, Edjay R.; Luo, Ruibai; Lyons, Gaelyn C.; Wilson, Kelli M.; Gallardo, Devorah C.; Isanogle,Kristine; Robinson,Christina; Mendoza, Arnulfo; Heske, Christine M.; Chen, Jinqui-Qiu; Luo, Xiaoling; Kelly, Alexander E.; Difilippantonio,Simone; Robey, Robert W.; Thomas, Craig J.; Sackett, Dan L.; Morrison,Deborah; Randazzo, Paul A.; Jenkins, Lisa M. Miller; Yohe, Marielle E.
  3. MOLECULAR CANCER THERAPEUTICS. 2021, Feb 1; 20(2): 307-319.
  1. 4.   Efficacy, Tolerability, and Pharmacokinetics of Combined Targeted MEK and Dual mTORC1/2 Inhibition in a Preclinical Model of Mucosal Melanoma
  2. Wei,Bih; Hoover, Shelley B.; Peer, Cody J.; Dwyer, Jennifer E.; Adissu, Hibret A.; Shankarappa, Priya; Yang, Howard; Lee, Maxwell; Peat, Tyler J.; Figg, William D.; Simpson, R. Mark
  3. MOLECULAR CANCER THERAPEUTICS. 2020, NOV 1; 19(11): 2308-2318.
  1. 5.   Targeting Protein Translation by Rocaglamide and Didesmethyirocaglamide to Treat MPNST and Other for Sarcomas
  2. Chang, Long-Sheng; Oblinger, Janet L.; Burns, Sarah S.; Huang, Jie; Anderson,Larry; Hollingshead,Melinda; Shen, Rulong; Pan, Li; Agarwal, Garima; Ren, Yulin; Roberts, Ryan D.; O'Keefe,Barry; Kinghorn, A. Douglas; Collins,Jerry
  3. MOLECULAR CANCER THERAPEUTICS. 2020, Mar; 19(3): 731-741.
  1. 6.   A frizzled-like cysteine rich domain in glypican-3 mediates Wnt binding and regulates hepatocellular carcinoma tumor growth in mice
  2. Li, Na; Wei, Liwen; Liu, Xiaoyu; Bai, Hongjun; Ye, Yvonne; Li, Dan; Li, Nan; Baxa,Ulrich; Wang, Qun; Lv, Ling; Chen, Yun; Feng, Mingqian; Lee, Byungkook; Gao, Wei; Ho, Mitchell
  3. Hepatology (Baltimore, Md.). 2019, OCT; 70(4): 1231-1245.
  1. 7.   A Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab followed by Bevacizumab Monotherapy in Patients with Advanced Kaposi Sarcoma
  2. Ramaswami, Ramya; Uldrick, Thomas S; Polizzotto, Mark N; Wyvill, Kathleen M; Goncalves, Priscila; Widell, Anaida; Lurain, Kathryn; Steinberg, Seth M; Figg, William D; Tosato, Giovanna; Whitby,Denise; Yarchoan, Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, JUL 15; 25(14): 4238-4247.
  1. 8.   Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers
  2. Wilsker,Deborah; Barrett, Allison M.; Dull,Angie; Lawrence,Scott; Hollingshead,Melinda; Chen, Alice; Kummar, Shivaani; Parchment,Ralph; Doroshow, James H.; Kinders,Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, MAY 15; 25(10): 3084-3095.
  1. 9.   Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib
  2. Kraft, Ira L.; Akshintala, Srivandana; Zhu, Yuelin; Lei, Haiyan; Derse-Anthony, Claudia; Dombi, Eva; Steinberg, Seth M.; Lodish, Maya; Waguespack, Steven G.; Kapustina, Oxana; Fox, Elizabeth; Balis, Frank M.; Merino, Maria J.; Meltzer, Paul S.; Glod, John W.; Shern, Jack F.; Widemann, Brigitte C.
  3. CLINICAL CANCER RESEARCH. 2018, Feb 15; 24(4): 753-765.
  1. 10.   Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay
  2. Ji, Jay; Zhang, Yiping; Redon, Christophe E.; Reinhold, William C.; Chen, Alice P.; Fogli, Laura K.; Holbeck, Susan L.; Parchment, Ralph; Hollingshead, Melinda; Tomaszewski, Joseph E.; Dudon, Quentin; Pommier, Yves; Doroshow, James H.; Bonner, William M.
  3. PLOS ONE. 2017, Feb 3; 12(2): e0171582.
  1. 11.   Antineoplastic Agents. 548. Synthesis of lodo- and Diiodocombstatin Phosphate Prodrugs
  2. Pettit, G. R.; Rosenberg, H. J.; Dixon, R.; Knight, J. C.; Hamel, E.; Chapuis, J. C.; Pettit, R. K.; Hogan, F.; Sumner, B.; Ain, K. B.; Trickey-Platt, B.
  3. Journal of Natural Products. 2012, Mar; 75(3): 385-393.
  1. 12.   The B-Raf Status of Tumor Cells May Be a Significant Determinant of Both Antitumor and Anti-Angiogenic Effects of Pazopanib in Xenograft Tumor Models
  2. Gril, B.; Palmieri, D.; Qian, Y.; Anwar, T.; Ileva, L.; Bernardo, M.; Choyke, P.; Liewehr, D. J.; Steinberg, S. M.; Steeg, P. S.
  3. Plos One. 2011, Oct; 6(10): 11.
  1. 13.   Comparison of GD2 binding capture ELISA assays for anti-GD2-antibodies using GD2-coated plates and a GD2-expressing cell-based ELISA
  2. Soman, G.; Yang, X. Y.; Jiang, H. G.; Giardina, S.; Mitra, G.
  3. Journal of Immunological Methods. 2011, Oct; 373(1-2): 181-191.
  1. 14.   Engineered Single Human CD4 Domains as Potent HIV-1 Inhibitors and Components of Vaccine Immunogens
  2. Chen, W. Z.; Feng, Y.; Gong, R.; Zhu, Z. Y.; Wang, Y. P.; Zhao, Q.; Dimitrov, D. S.
  3. Journal of Virology. 2011, Sep; 85(18): 9395-9405.
  1. 15.   Cytotoxic Activity of Immunotoxin SS1P Is Modulated by TACE-Dependent Mesothelin Shedding
  2. Zhang, Y. J.; Chertov, O.; Zhang, J. L.; Hassan, R.; Pastan, I.
  3. Cancer Research. 2011, Sep; 71(17): 5915-5922.
  1. 16.   One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates
  2. Denton, P. W.; Othieno, F.; Martinez-Torres, F.; Zou, W.; Krisko, J. F.; Fleming, E.; Zein, S.; Powell, D. A.; Wahl, A.; Kwak, Y. T.; Welch, B. D.; Kay, M. S.; Payne, D. A.; Gallay, P.; Appella, E.; Estes, J. D.; Lu, M.; Garcia, J. V.
  3. Journal of Virology. 2011, Aug; 85(15): 7582-7593.
  1. 17.   Population pharmacokinetic analysis of sorafenib in patients with solid tumours
  2. Jain, L.; Woo, S.; Gardner, E. R.; Dahut, W. L.; Kohn, E. C.; Kummar, S.; Mould, D. R.; Giaccone, G.; Yarchoan, R.; Venitz, J.; Figg, W. D.
  3. British Journal of Clinical Pharmacology. 2011, Aug; 72(2): 294-305.
  1. 18.   Plasma and CNS pharmacokinetics of O(4)-benzylfolic acid (O(4)BF) and metabolite in a non-human primate model
  2. Chuk, M. K.; Cole, D. E.; McCully, C.; Loktionova, N. A.; Pegg, A. E.; Parker, R. J.; Pauly, G.; Widemann, B. C.; Balis, F. M.; Fox, E.
  3. Cancer Chemotherapy and Pharmacology. 2011, Jun; 67(6): 1291-1297.
  1. 19.   Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies
  2. Gursel, D. B.; Connell-Albert, Y. S.; Tuskan, R. G.; Anastassiadis, T.; Walrath, J. C.; Hawes, J. J.; Amlin-Van Schaick, J. C.; Reilly, K. M.
  3. Neuro-Oncology. 2011, Jun; 13(6): 610-621.
  1. 20.   Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening
  2. Grohar, P. J.; Woldemichael, G. M.; Griffin, L. B.; Mendoza, A.; Chen, Q. R.; Yeung, C.; Currier, D. G.; Davis, S.; Khanna, C.; Khan, J.; McMahon, J. B.; Helman, L. J.
  3. Journal of the National Cancer Institute. 2011, Jun; 103(12): 962-978.
  1. 21.   Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers
  2. Butterfield, L. H.; Palucka, A. K.; Britten, C. M.; Dhodapkar, M. V.; Hakansson, L.; Janetzki, S.; Kawakami, Y.; Kleen, T. O.; Lee, P. P.; Maccalli, C.; Maecker, H. T.; Maino, V. C.; Maio, M.; Malyguine, A.; Masucci, G.; Pawelec, G.; Potter, D. M.; Rivoltini, L.; Salazar, L. G.; Schendel, D. J.; Slingluff, C. L.; Song, W. R.; Stroncek, D. F.; Tahara, H.; Thurin, M.; Trinchieri, G.; van Der Burg, S. H.; Whiteside, T. L.; Wigginton, J. M.; Marincola, F.; Khleif, S.; Fox, B. A.; Disis, M. L.
  3. Clinical Cancer Research. 2011, May; 17(10): 3064-3076.
  1. 22.   A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer
  2. Kelly, R. J.; Draper, D.; Chen, C. C.; Robey, R. W.; Figg, W. D.; Piekarz, R. L.; Chen, X. H.; Gardner, E. R.; Balis, F. M.; Venkatesan, A. M.; Steinberg, S. M.; Fojo, T.; Bates, S. E.
  3. Clinical Cancer Research. 2011, Feb; 17(3): 569-580.
  1. 23.   Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?
  2. Shurin, M. R.; Gregory, M.; Morris, J. C.; Malyguine, A. M.
  3. Expert Opinion on Biological Therapy. 2010, Nov; 10(11): 1539-1553.
  1. 24.   Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis
  2. Sangaletti, S.; Tripodo, C.; Ratti, C.; Piconese, S.; Porcasi, R.; Salcedo, R.; Trinchieri, G.; Colombo, M. P.; Chiodoni, C.
  3. Cancer Research. 2010, Oct; 70(20): 7764-7775.
  1. 25.   A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer
  2. Ahn, R. W.; Chen, F.; Chen, H. M.; Stern, S. T.; Clogston, J. D.; Patri, A. K.; Raja, M. R.; Swindell, E. P.; Parimi, V.; Cryns, V. L.; O'Halloran, T. V.
  3. Clinical Cancer Research. 2010, Jul; 16(14): 3607-3617.
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