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  1. 1.   Farnesyltransferase-Mediated Delivery of a Covalent Inhibitor Overcomes Alternative Prenylation to Mislocalize K-Ras
  2. Novotny, Chris J.; Hamilton, Gregory L.; McCormick, Frank; Shokat, Kevan M.
  3. ACS CHEMICAL BIOLOGY. 2017, Jul; 12(7): 1956-1962.
  1. 2.   Structural studies of vacuolar plasmepsins
  2. Bhaumik, P.; Gustchina, A.; Wlodawer, A.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2012, Jan; 1824(1): 207-223.
  1. 3.   The Role of Amino-Terminal Sequences in Cellular Localization and Antiviral Activity of APOBEC3B
  2. Pak, V.; Heidecker, G.; Pathak, V. K.; Derse, D.
  3. Journal of Virology. 2011, Sep; 85(17): 8538-8547.
  1. 4.   Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase
  2. Bahta, M.; Lountos, G. T.; Dyas, B.; Kim, S. E.; Ulrich, R. G.; Waugh, D. S.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2011, Apr; 54(8): 2933-2943.
  1. 5.   Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain
  2. Wexler-Cohen, Y.; Ashkenazi, A.; Viard, M.; Blumenthal, R.; Shai, Y.
  3. Faseb Journal. 2010, Nov; 24(11): 4196-4202.
  1. 6.   Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41
  2. Gustchina, E.; Li, M.; Louis, J. M.; Anderson, D. E.; Lloyd, J.; Frisch, C.; Bewley, C. A.; Gustchina, A.; Wlodawer, A.; Clore, G. M.
  3. Plos Pathogens. 2010, Nov; 6(11): 19.
  1. 7.   A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex
  2. Jacobs, A.; Quraishi, O.; Huang, X. C.; Bousquet-Gagnon, N.; Nault, G.; Francella, N.; Alvord, W. G.; Pham, N.; Soucy, C.; Robitaille, M.; Bridon, D.; Blumenthal, R.
  3. Journal of Biological Chemistry. 2007, Nov; 282(44): 32406-32413.
  1. 8.   theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation
  2. Gallo, S. A.; Wang, W.; Rawat, S. S.; Jung, G.; Waring, A. J.; Cole, A. M.; Lu, H.; Yan, X. X.; Daly, N. L.; Craik, D. J.; Jiang, S. B.; Lehrer, R. I.; Blumenthal, R.
  3. Journal of Biological Chemistry. 2006, Jul; 281(27): 18787-18792.
  1. 9.   New arylthioindoles: Potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies
  2. De Martino, G.; Edler, M. C.; La Regina, G.; Coluccia, A.; Barbera, M. C.; Barrow, D.; Nicholson, R. I.; Chiosis, G.; Brancale, A.; Hamel, E.; Artico, M.; Silvestri, R.
  3. Journal of Medicinal Chemistry. 2006, FEB 9; 49(3): 947-954.
  1. 10.   Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis
  2. Dorjsuren, D.; Burnette, A.; Gray, G. N.; Chen, X. L.; Zhu, W. M.; Roberts, P. E.; Currens, M. J.; Shoemaker, R. H.; Ricciardi, R. P.; Sei, S.
  3. Antiviral Research. 2006, JAN; 69(1): 9-23.
  1. 11.   Serotype-selective, small-molecule inhibitors of the zinc endopeptidase of botulinum neurotoxin serotype A
  2. Park, J. G.; Sill, P. C.; Makiyi, E. F.; Garcia-Sosa, A. T.; Millard, C. B.; Schmidt, J. J.; Pang, Y. P.
  3. Bioorganic & Medicinal Chemistry. 2006, Jan; 14(2): 395-408.
  1. 12.   Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-4
  2. Pettit, G. R.; Rhodes, M. R.; Herald, D. L.; Hamel, E.; Schmidt, J. M.; Pettitt, R. K.
  3. Journal of Medicinal Chemistry. 2005, JUN 16; 48(12): 4087-4099.
  1. 13.   Arylthioindoles, potent inhibitors of tubulin polymerization
  2. De Martino, G.; La Regina, G.; Coluccia, A.; Edler, M. C.; Barbera, M. C.; Brancale, A.; Wilcox, E.; Hamel, E.; Artico, M.; Silvestri, R.
  3. Journal of Medicinal Chemistry. 2004, DEC 2; 47(25): 6120-6123.
  1. 14.   A 4 '-C-ethynyl-2 ',3 '-dideoxynucleoside analogue highlights the role of the 3 '-OH in anti-HIV active 4 '-C-ethynyl-2 '-deoxy nucleosides
  2. Siddiqui, M. A.; Hughes, S. H.; Boyer, P. L.; Mitsuya, H.; Van, Q. N.; George, C.; Sarafinanos, S. G.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, OCT 7; 47(21): 5041-5048.
  1. 15.   Lipidic inhibitors of human N-myristoyltransferase
  2. Pasha, M. K.; Selvakumar, P.; Ashakumary, L.; Qureshi, M.; Guziec, F. S.; Dimmock, J. R.; Felsted, R. L.; Glover, C. J.; Sharma, R. K.
  3. International Journal of Molecular Medicine. 2004 13(4): 557-563.
  1. 16.   Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions
  2. Svarovskaia, E. S.; Barr, R.; Zhang, X. C.; Pais, G. C. G.; March, C.; Pommier, Y.; Burke, T. R.; Pathak, V. K.
  3. Journal of Virology. 2004 78(7): 3210-3222.
  1. 17.   Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2- SH2 domain
  2. Lung, F. D. T.; Lang, Y. Q.; King, C. R.; Varady, J.; Wu, X. W.; Wang, S.; Roller, P. P.
  3. Journal of Peptide Research. 2001 57(6): 447-454.
  1. 18.   Inactivation of Nitric Oxide Synthase By Substituted Aminoguanidines and Aminoisothioureas
  2. Wolff, D. J.; Gauld, D. S.; Neulander, M. J.; Southan, G.
  3. Journal of Pharmacology and Experimental Therapeutics. 1997 283(1): 265-273.
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