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  1. 1.   Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design
  2. Tran, Brandon; Pichling, Patricio; Tenney, Logan; Connelly, Colleen M; Moon, Michelle H; Ferré-D'Amaré, Adrian R; Schneekloth,Jay; Jones, Christopher P
  3. Cell chemical biology. 2020, OCT 15; 27(10): 1241-+.
  1. 2.   Enzyme dynamics point to stepwise conformational selection in catalysis
  2. Ma, B. Y.; Nussinov, R.
  3. Current Opinion in Chemical Biology. 2010, Oct; 14(5): 652-659.
  1. 3.   Reverse transcriptase in motion: Conformational dynamics of enzyme-substrate interactions
  2. Gotte, M.; Rausch, J. W.; March, B.; Sarafianos, S.; Le Grice, S. F. J.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2010, May; 1804(5): 1202-1212.
  1. 4.   Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long Terminal Repeat Retrotransposons: Dynamics of Enzyme: Substrate Interactions
  2. Fabris, D.; Marino, J. P.; Le Grice, S. F. J.
  3. Viruses-Basel. 2009, Dec; 1(3): 657-677.
  1. 5.   Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein
  2. Post, K.; Kankia, B.; Gopalakrishnan, S.; Yang, V.; Cramer, E.; Saladores, P.; Gorelick, R. J.; Guo, J. H.; Musier-Forsyth, K.; Levin, J. G.
  3. Nucleic Acids Research. 2009 37(6): 1755-1766.
  1. 6.   Integration of Rous Sarcoma Virus DNA: a CA Dinucleotide Is Not Required for Integration of the U3 End of Viral DNA
  2. Oh, J.; Chang, K. W.; Hughes, S. H.
  3. Journal of Virology. 2008 82(22): 11480-11483.
  1. 7.   Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo
  2. Oh, J.; McWilliams, M. J.; Julias, J. G.; Hughes, S. H.
  3. Journal of Virology. 2008 82(2): 719-727.
  1. 8.   High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers
  2. Yi-Brunozzi, H. Y.; Brinson, R. G.; Brabazon, D. I.; Lener, D.; Le Grice, S.; Marino, J. P.
  3. Chemistry & Biology. 2008 15(3): 254-262.
  1. 9.   In vitro analysis of the effects of mutations in the G-tract of the human immunodeficiency virus type 1 polypurine tract on RNase H cleavage specificity
  2. Jones, F. D.; Hughes, S. H.
  3. Virology. 2007, Apr; 360(2): 341-349.
  1. 10.   Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes
  2. Rausch, J. W.; Le Grice, S. F. J.
  3. Current HIV Research. 2007, Jan; 5(1): 11-22.
  1. 11.   Retrotransposon suicide: Formation of Ty1 circles and autointegration via a central DNA flap
  2. Garfinkel, D. J.; Stefanisko, K. M.; Nyswaner, K. M.; Moore, S. P.; Oh, J.; Hughes, S. H.
  3. Journal of Virology. 2006, Dec; 80(24): 11920-11934.
  1. 12.   Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization
  2. McWilliams, M. J.; Julias, J. G.; Sarafianos, S. G.; Alvord, W. G.; Arnold, E.; Hughes, S. H.
  3. Virology. 2006, May; 348(2): 378-388.
  1. 13.   Examining Ty3 polypurine tract structure and function by nucleoside analog interference
  2. Dash, C.; Marino, J. P.; Le Grice, S. F. J.
  3. Journal of Biological Chemistry. 2006, FEB 3; 281(5): 2773-2783.
  1. 14.   Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by Rous sarcoma virus RNase H but do cause aberrant integrations in vivo
  2. Oh, J.; Chang, K. W.; Hughes, S. H.
  3. Journal of Virology. 2006, JAN; 80(1): 451-459.
  1. 15.   Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function
  2. Mandal, D.; Dash, C.; Le Grice, S. F. J.; Prasad, V. R.
  3. Nucleic Acids Research. 2006 34(10): 2853-2863.
  1. 16.   A ribose sugar conformational switch in the LTR-retrotransposon Ty3 polypurine tract-containing RNA/DNA hybrid
  2. Yi-Brunozzi, H. Y.; Brabazon, D. M.; Lener, D.; Le Grice, S. F. J.; Marino, J. P.
  3. Journal of the American Chemical Society. 2005, NOV 30; 127(47): 16344-16345.
  1. 17.   Alternate polypurine tracts (PPTs) affect the Rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction
  2. Chang, K. W.; Julias, J. G.; Alvord, W. G.; Oh, J.; Hughes, S. H.
  3. Journal of Virology. 2005, NOV; 79(21): 13694-13704.
  1. 18.   Investigating HIV-1 polypurine tract geometry via targeted insertion of abasic lesions in the (-)-DNA template and (+)-RNA primer
  2. Yi-Brunozzi, H. Y.; Le Grice, S. F. J.
  3. Journal of Biological Chemistry. 2005, MAY 20; 280(20): 20154-20162.
  1. 19.   Effect of cell cycle inhibition on cisplatin-induced cytotoxicity
  2. Fishel, M. L.; Newell, D. R.; Griffin, R. J.; Davison, R.; Wang, L. Z.; Curtin, N. J.; Zuhowski, E. G.; Kasza, K.; Egorin, M. J.; Moschel, R. C.; Dolan, M. E.
  3. Journal of Pharmacology and Experimental Therapeutics. 2005, JAN; 312(1): 206-213.
  1. 20.   Intra- and intercellular variations in the repair efficiency of O-6-methylguanine, and their contribution to kinetic complexity
  2. Souliotis, V. L.; Sfikakis, P. P.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2004, DEC 21; 568(2): 155-170.
  1. 21.   Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage
  2. Julias, J. G.; McWilliams, M. J.; Sarafianos, S. G.; Alvord, W. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, DEC; 78(23): 13315-13324.
  1. 22.   Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3 ' polypurine tract
  2. Dash, C.; Rausch, J. W.; Le Grice, S. F. J.
  3. Nucleic Acids Research. 2004 32(4): 1539-1547.
  1. 23.   cis-acting and trans-acting modulation of equine infectious anemia virus alternative RNA splicing
  2. Liao, H. J.; Baker, C. C.; Princler, G. L.; Derse, D.
  3. Virology. 2004 323(1): 131-140.
  1. 24.   PROSIT: Pseudo-Rotational Online Service and Interactive Tool, applied to a conformational survey of nucleosides and nucleotides
  2. Sun, G.; Voigt, J. H.; Filippov, I. V.; Marquez, V. E.; Nicklaus, M. C.
  3. Journal of Chemical Information and Computer Sciences. 2004, SEP-OCT; 44(5): 1752-1762.
  1. 25.   2-substitution of adenine nucleotide analogues containing a bicyclo 3.1.0 hexane ring system locked in a northern conformation: Enhanced potency as P2Y(1) receptor antagonists
  2. Kim, H. S.; Ohno, M.; Xu, B.; Kim, H. O.; Choi, Y. S.; Ji, X. D.; Maddileti, S.; Marquez, V. E.; Harden, T. K.; Jacobson, K. A.
  3. Journal of Medicinal Chemistry. 2003 46(23): 4974-4987.
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