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  1. 1.   Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model
  2. Yamamoto, Jun; Murata, Takuya; Sugisawa, Norihiko; Higuchi, Takashi; Tashiro, Yoshihiko; Nishino, Hiroto; Inubushi, Sachiko; Sun, Y U; Lim, Hyein; Miyake, Kentaro; Shimoya, Koichiro; Nomura, Tsunehisa; Kurebayashi, Junichi; Tanino, Hirokazu; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2475-2479.
  1. 2.   A Single Low Dose of Eribulin Regressed a Highly Aggressive Triple-negative Breast Cancer in a Patient-derived Orthotopic Xenograft Model
  2. Lim, Hye In; Yamamoto, Jun; Inubushi, Sachiko; Nishino, Hiroto; Tashiro, Yoshihiko; Sugisawa, Norihiko; Han, Quinhong; Sun, Y U; Choi, Hee Jun; Nam, Seok Jin; Kim, Moon Bo; Lee, Ji Sun; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2481-2485.
  1. 3.   A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib
  2. Yamamoto, Jun; Murata, Takuya; Tashiro, Yoshihiko; Higuchi, Takashi; Sugisawa, Norihiko; Nishino, Hiroto; Inubushi, Sachiko; Sun, Y U; Lim, Hyein; Miyake, Kentaro; Hongo, Atsushi; Nomura, Tsunehisa; Saitoh, Wataru; Moriya, Takuya; Tanino, Hirokazu; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2509-2514.
  1. 4.   Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Higuchi, Takashi; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer genomics & proteomics. 2020, Jul-Aug; 17(4): 351-358.
  1. 5.   The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Oshiro, Hiromichi; Han, Qinghong; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Tan, Yuying; Kuchipudi, Shreya; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer chemotherapy and pharmacology. 2019, Nov 08;
  1. 6.   Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model
  2. Park, Jun Ho; Zhao, Ming; Han, Qinghong; Sun, Yu; Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Singh,Shree Ram; Clary, Bryan; Bouvet, Michael; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2019, Oct 15; 518(2): 306-310.
  1. 7.   The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model
  2. Miyake, Kentaro; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Sugisawa, Norihiko; Park, Jun Ho; Razmjooei, Sahar; Katsuya, Yuki; Barangi, Maryam; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Homma, Yuki; Hiroshima, Yukihiko; Matsuyama, Ryusei; Bouvet, Michael; Chawla, Sant P; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019, SEP; 117: 109093.
  1. 8.   Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Kiyuna, Tasuku; Tome, Yasunori; Miyake, Kentaro; Murakami, Takashi; Oshiro, Hiromichi; Igarashi, Kentaro; Kawaguchi, Kei; Hsu, John; Singh, Manish; Li, Yunfeng; Nelson, Scott; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4775-4779.
  1. 9.   Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells
  2. Park, Jun Ho; Zhao, Ming; Oshiro, Hiromichi; Miyake, Kentaro; Higuchi, Takashi; Reynoso, Jose; Razmjooei, Sahar; Bouvet, Michael; Clary, Bryan; Zhang, Zhiying; Sugisawa, Norihiko; Yamamoto, Jun; Singh,Shree Ram; Hoffman, Robert M
  3. Anticancer research. 2019, Jul; 39(7): 3463-3467.
  1. 10.   The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Miyake, Kentaro; Sugisawa, Norihiko; Oshiro, Hiromichi; Zhang, Zhiying; Razmjooei, Sahar; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M.
  3. CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2019, Jun; 83(6): 1075-1082.
  1. 11.   Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model
  2. Miyake, Kentaro; Murata, Takuya; Murakami, Takashi; Zhao, Ming; Kiyuna, Tasuku; Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Masuyo; Lwin, Thinzar M.; Hozumi, Chihiro; Komatsu, Shin; Kikuchi, Takashi; Bouvet, Michael; Shimoya, Koichiro; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M.
  3. Archives of gynecology and obstetrics. 2019, JUN; 299(6): 1683-1690.
  1. 12.   Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model
  2. Higuchi, Takashi; Miyake, Kentaro; Sugisawa, Norihiko; Oshiro, Hiromichi; Zhang, Zhiying; Razmjooei, Sahar; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh, Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer letters. 2019, Jun 1; 451: 122-127.
  1. 13.   Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Higuchi, Takashi; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 107-111.
  1. 14.   Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model
  2. Oshiro, Hiromichi; Tome, Yasunori; Kiyuna, Tasuku; Miyake, Kentaro; Kawaguchi, Kei; Higuchi, Takashi; Miyake, Masuyo; Zang, Zhiying; Razmjooei, Sahar; Barangi, Maryam; Wangsiricharoen, Sintawat; Nelson, Scott D; Li, Yunfeng; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 17-23.
  1. 15.   Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model
  2. Miyake, Kentaro; Kiyuna, Tasuku; Kawaguchi, Kei; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Wangsiricharoen, Sintawat; Razmjooei, Sahar; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Hiroshima, Yukihiko; Matsuyama, Ryusei; Bouvet, Michael; Chawla, Sant P; Singh, Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Cancer chemotherapy and pharmacology. 2019, May; 83(5): 809-815.
  1. 16.   Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model
  2. Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Kawaguchi, Kei; Zhang, Zhiying; Wangsiricharoen, Sintawat; Razmjooei, Sahar; Oshiro, Hiromichi; Higuchi, Takashi; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Hiroshima, Yukihiko; Kumamoto, Takafumi; Matsuyama, Ryusei; Bouvet, Michael; Singh, Shree Ram; Chawla, Sant P; Endo, Itaru; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2019, FEB 19; 509(4): 1041-1046.
  1. 17.   Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model
  2. Miyake, Kentaro; Kiyuna, Tasuku; Li, Shukuan; Han, Qinghong; Tan, Yuying; Zhao, Ming; Oshiro, Hiromichi; Kawaguchi, Kei; Higuchi, Takashi; Zhang, Zhiying; Razmjooei, Sahar; Barangi, Maryam; Wangsiricharoen, Sintawat; Murakami, Takashi; Singh, Arun S.; Li, Yunfeng; Nelson, Scott D.; Eilber, Fritz C.; Bouvet, Michael; Hiroshima, Yukihiko; Chishima, Takashi; Matsuyama, Ryusei; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M.
  3. Chemotherapy. 2019, Feb; 63(5): 278-283.
  1. 18.   Detection of Metastasis in a Patient-derived Orthotopic Xenograft (PDOX) Model of Undifferentiated Pleomorphic Sarcoma with Red Fluorescent Protein
  2. Oshiro, Hiromichi; Kiyuna, Tasuku; Tome, Yasunori; Miyake, Kentaro; Kawaguchi, Kei; Higuchi, Takashi; Miyake, Masuyo; Zhang, Zhiying; Razmjooei, Sahar; Barangi, Maryam; Wangsiricharoen, Sintawat; Nelson, Scott D.; Li, Yunfeng; Bouvet, Michael; Singh, Shree Ram; Kanaya, Fuminori; Hoffman, Robert M.
  3. Anticancer research. 2019, Jan; 39(1): 81-85.
  1. 19.   A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model
  2. Kiyuna, Tasuku; Tome, Yasunori; Murakami, Takashi; Miyake, Kentaro; Igarashi, Kentaro; Kawaguchi, Kei; Oshiro, Hiromichi; Higuchi, Takashi; Miyake, Masuyo; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Chawla, Sant; Kanaya, Fuminori; Eilber, Fritz C; Singh, Shree Ram; Zhao, Ming; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2018, Nov 2; 505(3): 733-739.
  1. 20.   Tumor-targeting Salmonella typhimurium A1-R overcomes partial carboplatinum-resistance of a cancer of unknown primary (CUP)
  2. Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Zhao, Ming; Wangsiricharoen, Sintawat; Kawaguchi, Kei; Zhang, Zhiying; Higuchi, Takashi; Razmjooei, Sahar; Li, Yunfeng; Nelson, Scott D.; Russell, Tara; Singh, Arun; Murakami, Takashi; Hiroshima, Yukihiko; Momiyama, Masashi; Matsuyama, Ryusei; Chishima, Takashi; Singh,Shree Ram; Chawla, Sant P.; Eilber, Fritz C.; Endo, Itaru; Hoffman, Robert M.
  3. TISSUE & CELL. 2018, OCT; 54: 144-149.
  1. 21.   Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
  2. Kiyuna, Tasuku; Tome, Yasunori; Murakami, Takashi; Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Miyake, Masuyo; Li, Yunfeng; Nelson, Scott D; Dry, Sarah M; Singh, Arun S; Russell, Tara A; Elliott, Irmina; Singh, Shree Ram; Kanaya, Fuminori; Eilber, Fritz C; Hoffman, Robert M
  3. BMC cancer. 2018, Aug 20; 18(1): 840.
  1. 22.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
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