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  1. 1.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 2.   Inferring phase transitions and critical exponents from limited observations with thermodynamic maps
  2. Herron, Lukas; Mondal, Kinjal; Schneekloth,Jay; Tiwary, Pratyush
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Dec 24; 121(52): e2321971121.
  1. 3.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 4.   CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells
  2. Chen,Zibo; Liu,Xi; Kawakami, Masanori; Liu,Xiuxia; Baker, Allison; Bhatawadekar, Aayush; Tyutyunyk-Massey,Liliya; Narayan,Kedar; Dmitrovsky,Ethan
  3. Cancer Biology & Therapy. 2023, Dec 31; 24(1): 2279241.
  1. 5.   Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials?
  2. Potter, Gail E; Callier,Viviane; Shrestha, Biraj; Joshi, Sudhaunshu; Dwivedi, Ankit; Silva, Joana C; Laurens, Matthew B; Follmann, Dean A; Deye, Gregory A
  3. Malaria Journal. 2023, Dec 19; 22(1): 383.
  1. 6.   A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma
  2. Atkins, Sarah L P; Greer, Yoshimi Endo; Jenkins, Sarah; Gatti-Mays, Margaret E; Houston, Nicole; Lee, Sunmin; Lee, Min-Jung; Rastogi, Shraddha; Sato, Nahoko; Burks,Christina; Annunziata, Christina M; Lee, Jung-Min; Nagashima, Kunio; Trepel, Jane B; Lipkowitz, Stanley; Zimmer, Alexandra S
  3. The Oncologist. 2023, Jun 05;
  1. 7.   Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer
  2. Monge, Cecilia; Xie, Changqing; Myojin, Yuta; Coffman, Kelley; Hrones, Donna Mabry; Wang, Sophie; Hernandez, Jonathan M; Wood, Bradford J; Levy, Elliot B; Juburi, Israa; Hewitt, Stephen M; Kleiner, David E; Steinberg, Seth M; Figg, William D; Redd, Bernadette; Homan,Philip; Cam, Maggie; Ruf, Benjamin; Duffy, Austin G; Greten, Tim F
  3. Journal for Immunotherapy of Cancer. 2023, Feb; 11(2):
  1. 8.   Scaffolding viral protein NC nucleates phase separation of the HIV-1 biomolecular condensate
  2. Monette, Anne; Niu, Meijuan; Nijhoff Asser, Maya; Gorelick,Robert; Mouland, Andrew J
  3. Cell Reports. 2022, Aug 23; 40(8): 111251.
  1. 9.   Efficacy of Cochleated Amphotericin B in Mouse and Human Mucocutaneous Candidiasis
  2. Desai, Jigar V; Urban,Amanda; Swaim,Doris; Colton, Benjamin; Kibathi, Lilian W; Ferrè, Elise M N; Stratton, Pamela; Merideth, Melissa A; Hunsberger, Sally; Matkovits, Theresa; Mannino, Raphael; Holland, Steven M; Tramont, Edmund; Lionakis, Michail S; Freeman, Alexandra F
  3. Antimicrobial Agents and Chemotherapy. 2022, Jun 14; e0030822.
  1. 10.   Safety and immunogenicity of an HIV-1 prefusion-stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label, randomized, dose-escalation, phase 1 clinical trial
  2. Houser, Katherine V; Gaudinski, Martin R; Happe, Myra; Narpala, Sandeep; Verardi, Raffaello; Sarfo, Edward K; Corrigan, Angela R; Wu, Richard; Rothwell, Ro Shauna; Novik, Laura; Hendel, Cynthia S; Gordon, Ingelise J; Berkowitz, Nina M; Cartagena, Cora Trelles; Widge, Alicia T; Coates, Emily E; Strom, Larisa; Hickman, Somia; Conan-Cibotti, Michelle; Vazquez, Sandra; Trofymenko, Olga; Plummer, Sarah; Stein, Judy; Case,Christopher; Nason, Martha; Biju, Andrea; Parchment, Danealle K; Changela, Anita; Cheng, Cheng; Duan, Hongying; Geng, Hui; Teng, I-Ting; Zhou, Tongqing; O'Connell, Sarah; Barry, Chris; Carlton, Kevin; Gall, Jason G; Flach, Britta; Doria-Rose, Nicole A; Graham, Barney S; Koup, Richard A; McDermott, Adrian B; Mascola, John R; Kwong, Peter D; Ledgerwood, Julie E
  3. EClinicalMedicine. 2022, Jun; 48: 101477.
  1. 11.   A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer
  2. Manzo, Julia; Puhalla, Shannon; Pahuja, Shalu; Ding, Fei; Lin, Yan; Appleman, Leonard; Tawbi, Hussein; Stoller, Ronald; Lee, James J; Diergaarde, Brenda; Kiesel, Brian F; Yu, Jing; Tan, Antoinette R; Belani, Chandra P; Chew, Helen; Garcia, Agustin A; Morgan, Robert J; Wahner Hendrickson, Andrea E; Visscher, Daniel W; Hurley, Rachel M; Kaufmann, Scott H; Swisher, Elizabeth M; Oesterreich, Steffi; Katz, Tiffany; Ji,Jay; Zhang, Yiping; Parchment, Ralph E; Chen, Alice; Duan, Wenrui; Giranda, Vincent; Shepherd, Stacie P; Ivy, S Percy; Chu, Edward; Beumer, Jan H
  3. Cancer Chemotherapy and Pharmacology. 2022, Apr 18; 89(5): 721-735.
  1. 12.   The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation
  2. Lyonnais, Sébastien; Sadiq, S Kashif; Lorca-Oró, Cristina; Dufau, Laure; Nieto-Marquez, Sara; Escribà, Tuixent; Gabrielli, Natalia; Tan, Xiao; Ouizougun-Oubari, Mohamed; Okoronkwo, Josephine; Reboud-Ravaux, Michèle; Gatell, José Maria; Marquet, Roland; Paillart, Jean-Christophe; Meyerhans, Andreas; Tisné, Carine; Gorelick,Robert; Mirambeau, Gilles
  3. Viruses. 2021, Nov 19; 13(11):
  1. 13.   The mechanism driving a solid-solid phase transition in a biomacromolecular crystal
  2. Ramakrishnan, Saminathan; Stagno,Jason; Heinz,Will; Zuo, Xiaobing; Yu,Ping; Wang,Yun-Xing
  3. IUCrJ. 2021, Jul 01; 8(Pt 4): 655-664.
  1. 14.   Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
  2. Zhao, Huaying; Nguyen, Ai; Li, Yan; Adao, Regina C.; Valkov,Eugene; Patterson, George H.; Piszczek, Grzegorz; Schuck, Peter
  3. iScience. 2021, Jun 25; 24(6):
  1. 15.   A combined approach to characterize ligand-induced solid-solid phase transitions in biomacromolecular crystals
  2. Ramakrishnan, Saminathan; Stagno,Jason; Magidson,Valentin; Heinz,Will; Wang,Yun-Xing
  3. Journal of applied crystallography. 2021, Jun 01; 54(Pt 3): 787-796.
  1. 16.   Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs
  2. LeBlanc, Amy K.; Mazcko, Christina N.; Cherukuri, Aswini; Berger,Erika; Kisseberth, William C.; Brown, Megan E.; Lana, Susan E.; Weishaar, Kristen; Flesner, Brian K.; Bryan, Jeffrey N.; Vail, David M.; Burton, Jenna H.; Willcox, Jennifer L.; Mutsaers, Anthony J.; Woods, J. Paul; Northrup, Nicole C.; Saba, Corey; Curran, Kaitlin M.; Leeper, Haley; Wilson-Robles, Heather; Wustefeld-Janssens, Brandan G.; Lindley, Stephanie; Smith, Annette N.; Dervisis, Nikolaos; Klahn, Shawna; Higginbotham, Mary Lynn; Wouda, Raelene M.; Krick, Erika; Mahoney, Jennifer A.; London, Cheryl A.; Barber, Lisa G.; Balkman, Cheryl E.; McCleary-Wheeler, Angela L.; Suter, Steven E.; Martin, Olya; Borgatti, Antonella; Burgess, Kristine; Childress, Michael O.; Fidel, Janean L.; Allstadt, Sara D.; Gustafson, Daniel L.; Selmic, Laura E.; Khanna, Chand; Fan, Timothy M.
  3. CLINICAL CANCER RESEARCH. 2021, Jun 1; 27: 3005-3016.
  1. 17.   Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors
  2. Takebe, Naoko; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Collins, Jerry; Reid, Joel M; Piekarz, Richard; Moore, Nancy; Juwara, Lamin; Johnson,Barry; Bishop, Rachel; Lin, Frank I; Mena, Esther; Choyke, Peter L; Lindenberg, M Liza; Rubinstein, Larry V; Bonilla, Cecilia Monge; Goetz, Matthew P; Ames, Matthew M; McGovern, Renee M; Streicher, Howard; Covey, Joseph M; Doroshow, James H; Chen, Alice P
  3. Oncotarget. 2021, Feb 16; 12(4): 268-277.
  1. 18.   Fourteen-day PET/CT imaging to monitor drug combination activity in treated individuals with tuberculosis
  2. Xie, Yingda L.; de Jager, Veronique R.; Chen, Ray Y.; Dodd, Lori E.; Paripati, Praveen; Via, Laura E.; Follmann, Dean; Wang,Jing; Lumbard, Keith; Lahouar, Saher; Malherbe, Stephanus T.; Andrews, Jenna; Yu, Xiang; Goldfeder, Lisa C.; Cai, Ying; Arora, Kriti; Loxton, Andre G.; Vanker, Naadira; Duvenhage,Michael; Winter, Jill; Song, Taeksun; Walzl, Gerhard; Diacon, Andreas H.; Barry, Clifton E.
  3. Science Translational Medicine. 2021, Feb 3; 13(579):
  1. 19.   Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma
  2. Kowalczyk, Joshua T.; Wan, Xiaolin; Hernandez, Edjay R.; Luo, Ruibai; Lyons, Gaelyn C.; Wilson, Kelli M.; Gallardo, Devorah C.; Isanogle,Kristine; Robinson,Christina; Mendoza, Arnulfo; Heske, Christine M.; Chen, Jinqui-Qiu; Luo, Xiaoling; Kelly, Alexander E.; Difilippantonio,Simone; Robey, Robert W.; Thomas, Craig J.; Sackett, Dan L.; Morrison,Deborah; Randazzo, Paul A.; Jenkins, Lisa M. Miller; Yohe, Marielle E.
  3. MOLECULAR CANCER THERAPEUTICS. 2021, Feb 1; 20(2): 307-319.
  1. 20.   A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis
  2. Horne, Eric A; Diaz, Philippe; Cimino, Patrick J; Jung, Erik; Xu, Cong; Hamel,Ernest; Wagenbach, Michael; Kumasaka, Debra; Wageling, Nicholas B; Azorín, Daniel D; Winkler, Frank; Wordeman, Linda G; Holland, Eric C; Stella, Nephi
  3. Neuro-oncology advances. 2021, Jan-Dec; 3(1): vdaa165.
  1. 21.   Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4's ring-to-dot localization conversion around a human centriole
  2. Park, Jung-Eun; Meng, Lingjun; Ryu, Eun Kyoung; Nagashima,Kunio; Baxa,Ulrich; Bang, Jeong Kyu; Lee, Kyung S
  3. Cell Cycle. 2020, Dec; 1-18.
  1. 22.   Efficacy, Tolerability, and Pharmacokinetics of Combined Targeted MEK and Dual mTORC1/2 Inhibition in a Preclinical Model of Mucosal Melanoma
  2. Wei,Bih; Hoover, Shelley B.; Peer, Cody J.; Dwyer, Jennifer E.; Adissu, Hibret A.; Shankarappa, Priya; Yang, Howard; Lee, Maxwell; Peat, Tyler J.; Figg, William D.; Simpson, R. Mark
  3. MOLECULAR CANCER THERAPEUTICS. 2020, NOV 1; 19(11): 2308-2318.
  1. 23.   Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED
  2. Zhu, Lan; Bu, Guanhong; Jing, Liang; Shi,Dan; Lee, Ming-Yue; Gonen, Tamir; Liu, Wei; Nannenga, Brent L
  3. Structure (London, England : 1993). 2020, OCT 6; 28(10): 1149-+.
  1. 24.   Helminth Mediated Attenuation of Systemic Inflammation and Microbial Translocation in Helminth-Diabetes Comorbidity
  2. Rajamanickam, Anuradha; Munisankar, Saravanan; Menon, Pradeep A.; Dolla, Chandrakumar; Nutman, Thomas B.; Babu, Subash
  3. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2020, AUG 31; 10: 431.
  1. 25.   G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA
  2. Simko,Eric; Liu, Honghe; Zhang, Tao; Velasquez, Adan; Teli, Shraddha; Haeusler, Aaron R.; Wang, Jiou
  3. NUCLEIC ACIDS RESEARCH. 2020, JUL 27; 48(13): 7421-7438.
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