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  1. 1.   Protein Phosphatase 1 Regulatory Subunit PNUTS Prevents CENP-A Mislocalization and Chromosomal Instability
  2. Balachandra, Vinutha; Thomas, Makenzie; Shrestha, Roshan L; Sethi, Subhash Chandra; Chari,Rajagopal; Lin, Shinjen; Chih-Chien Cheng, Ken; Karpova, Tatiana S; Caplen, Natasha J; Basrai, Munira A
  3. Molecular and Cellular Biology. 2025, Apr 24; 1-13.
  1. 2.   Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors
  2. Ng,Martin; Wang, Huanchen; Zhang, Haibo; Prucker, Isabel; Perera, Lalith; Goncharova,Katya; Wamiru,Antony; Jessen, Henning J; Stanley, Robin E; Shears, Stephen B; Luo, Ji; O'Keefe,Barry; Wilson,Brice
  3. The Journal of Biological Chemistry. 2025, Feb 06; 108274.
  1. 3.   Adapting recombinant bacterial alkaline phosphatase for nucleotide exchange of small GTPases
  2. Frank,Peter; Hong, Min; Higgins, Brianna; Perkins, Shelley; Taylor, Troy; Wall,Vanessa; Drew,Matt; Waybright, Timothy; Gillette,Bill; Esposito,Dom; Messing, Simon
  3. Protein Expression and Purification. 2024, Feb 21; 106446.
  1. 4.   SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities
  2. Liu,Yonglan; Zhang,Wengang; Jang,Hyunbum; Nussinov,Ruth
  3. Cellular and Molecular Life Sciences : CMLS. 2023, Dec 12; 81(1): 5.
  1. 5.   Heterobifunctional molecules tackle targeted protein dephosphorylation
  2. Sibley, Christopher D; Schneekloth, John S
  3. Trends in Pharmacological Sciences. 2022, Jan 28;
  1. 6.   Assessment of Osteoporosis and Fracture Risk in Mastocytosis within a North American Cohort
  2. Makovoz, Ayelet; Wang,Jing; Oshegbo, Gloria; Park, Young Hwan; Lyons, Jonathan J; Eisch, A Robin; Scott, Linda M; Reynolds, James C; Ortega-Villa, Ana M; Metcalfe, Dean D; Komarow, Hirsh D
  3. The journal of allergy and clinical immunology. In practice. 2021, Dec; 9(12): 4459-4467.e10.
  1. 7.   Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses
  2. Uyanik, Burhan; Goloudina, Anastasia R.; Akbarali, Aamir; Grigorash, Bogdan B.; Petukhov, Alexey V.; Singhal, Sunil; Eruslanov, Evgeniy; Chaloyard, Jeanne; Lagorgette, Lisa; Hadi, Tarik; Baidyuk, Ekaterina V.; Sakai, Hiroyasu; Tessarollo,Lino; Ryffel, Bernhard; Mazur, Sharlyn J.; Lirussi, Frederic; Garrido, Carmen; Appella, Ettore; Demidov, Oleg N.
  3. NATURE COMMUNICATIONS. 2021, Jun 15; 12(1):
  1. 8.   Clinical and Immunologic Predictors of Mycobacterium avium Complex Immune Reconstitution Inflammatory Syndrome in a Contemporary Cohort of Patients With Human Immunodeficiency Virus
  2. Breglio, Kimberly F; Vinhaes, Caian L; Arriaga, María B; Nason, Martha; Roby, Gregg; Adelsberger, Joseph; Andrade, Bruno B; Sheikh, Virginia; Sereti, Irini
  3. The Journal of infectious diseases. 2021, Jun 15; 223(12): 2124-2135.
  1. 9.   The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane
  2. Jang,Hyunbum; Smith, Iris Nira; Eng, Charis; Nussinov,Ruth
  3. iScience. 2021, May 21; 24(5):
  1. 10.   Structure and Activity of PPX/GppA Homologs from Escherichia coli and Helicobacter pylori
  2. Song, He; Dharmasena, Madushini N; Wang, Chao; Shaw,Gary; Cherry,Scott; Tropea,Joseph; Jin,Ding; Ji,Xinhua
  3. The FEBS journal. 2020, May; 287(9): 1865-1885.
  1. 11.   Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens
  2. Clausse, Victor; Tao, Dingyin; Debnath, Subrata; Fang, Yuhong; Tagad, Harichandra D; Wang, Yuhong; Sun, Hongmao; LeClair, Christopher A; Mazur, Sharlyn J; Lane, Kelly; Shi, Zhen-Dan; Vasalatiy, Olga; Eells, Rebecca; Baker, Lynn K; Henderson, Mark J; Webb, Martin R; Shen, Min; Hall, Matthew D; Appella, Ettore; Appella, Daniel H; Coussens,Nathan
  3. The Journal of biological chemistry. 2019, Nov 15; 294(46): 17654-17668.
  1. 12.   Targeting Protein-Protein Interactions of Tyrosine Phosphatases with Microarrayed Fragment Libraries Displayed on Phosphopeptide Substrate Scaffolds
  2. Hogan, Megan; Bahta, Medhanit; Tsuji, Kohei; Nguyen, Trung X.; Cherry,Scott; Lountos,George; Tropea,Joseph; Zhao, Bryan M.; Zhao,Xue Zhi; Waugh,David; Burke,Terrence; Ulrich, Robert G.
  3. ACS COMBINATORIAL SCIENCE. 2019, Mar 11; 21: 158-170.
  1. 13.   High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design
  2. Lountos, George; Raran-Kurussi, Sreejith; Zhao, Bryan M; Dyas, Beverly K; Burke, Terrence; Ulrich, Robert G; Waugh, David
  3. Acta crystallographica. Section D, Structural biology. 2018, Oct 01; 74(Pt 10): 1015-1026.
  1. 14.   MBP-binding DARPins facilitate the crystallization of an MBP fusion protein
  2. Gumpena, Rajesh; Lountos, George; Waugh, David
  3. Acta Crystallographica. Section F, Structural Biology Communications. 2018, Sep 01; 74(Pt 9): 549-557.
  1. 15.   Crosstalk between PKC alpha and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium
  2. Hsu, Alice; Lum, Michelle A.; Shim, Kang-Sup; Frederick, Peter J.; Morrison, Carl D.; Chen, Baojiang; Lele, Subodh M.; Sheinin, Yuri M.; Daikoku, Takiko; Dey, Sudhansu K.; Leone, Gustavo; Black, Adrian R.; Black, Jennifer D.
  3. CELL REPORTS. 2018, Jul 17; 24(3): 655-669.
  1. 16.   Crystal structure of the human dual specificity phosphatase 1 catalytic domain
  2. Gumpena, Rajesh; Lountos, George; Raran-Kurussi, Sreejith; Tropea, Joseph; Cherry, Scott; Waugh, David
  3. Protein science : a publication of the Protein Society. 2018, Feb; 27(2): 561-567.
  1. 17.   Activity-Dependent Neuroplasticity Induced by an Enriched Environment Reverses Cognitive Deficits in Scribble Deficient Mouse
  2. Hilal, Muna L; Moreau, Maité M; Racca, Claudia; Pinheiro, Vera L; Piguel, Nicolas H; Santoni, Marie-Josée; Dos Santos Carvalho, Steve; Blanc, Jean-Michel; Abada, Yah-Se K; Peyroutou, Ronan; Medina, Chantal; Doat, Hélène; Papouin, Thomas; Vuillard, Laurent; Borg, Jean-Paul; Rachel, Rivka; Panatier, Aude; Montcouquiol, Mireille; Oliet, Stéphane H R; Sans, Nathalie
  3. Cerebral cortex (New York, N.Y. : 1991). 2017, Dec; 27(12): 5635-5651.
  1. 18.   NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction
  2. Juhasz, Agnes; Markel, Susan; Gaur, Shikha; Liu, Han; Lu, Jiamo; Jiang, Guojian; Wu, Xiwei; Antony, Smitha; Wu, Yongzhong; Melillo, Giovanni; Meitzler, Jennifer L; Haines, Diana; Butcher, Donna; Roy, Krishnendu; Doroshow, James H
  3. Journal of Biological Chemistry. 2017, May 12; 292(19): 7866-7887.
  1. 19.   Phosphatase-Stable Phosphoamino Acid Mimetics That Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1.
  2. Hymel, David; Burke, Terrence R
  3. ChemMedChem. 2017, Feb 3; 12(3): 202-206.
  1. 20.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 21.   14-3-3 Proteins: Diverse functions in cell proliferation and cancer progression
  2. Freeman, A. K.; Morrison, D. K.
  3. Seminars in Cell & Developmental Biology. 2011, Sep; 22(7): 681-687.
  1. 22.   Cysteine 81 Is Critical for the Interaction of S100A4 and Myosin-IIA
  2. Dulyaninova, N. G.; Hite, K. M.; Zencheck, W. D.; Scudiero, D. A.; Almo, S. C.; Shoemaker, R. H.; Bresnick, A. R.
  3. Biochemistry. 2011, Aug; 50(33): 7218-7227.
  1. 23.   Structure of human dual-specificity phosphatase 27 at 2.38 angstrom resolution
  2. Lountos, G. T.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2011, May; 67: 471-479.
  1. 24.   Cloning, expression, purification, crystallization and preliminary X-ray diffraction data of the Pyrococcus horikoshii RadA intein
  2. Lyskowski, A.; Oeemig, J. S.; Jaakkonen, A.; Rommi, K.; DiMaio, F.; Zhou, D. W.; Kajander, T.; Baker, D.; Wlodawer, A.; Goldman, A.; Iwai, H.
  3. Acta Crystallographica Section F-Structural Biology and Crystallization Communications. 2011, May; 67: 623-626.
  1. 25.   Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122
  2. Boutz, D. R.; Collins, P. J.; Suresh, U.; Lu, M. Z.; Ramirez, C. M.; Fernandez-Hernando, C.; Huang, Y. F.; Abreu, R. D.; Le, S. Y.; Shapiro, B. A.; Liu, A. M.; Luk, J. M.; Aldred, S. F.; Trinklein, N. D.; Marcotte, E. M.; Penalva, L. O. F.
  3. Journal of Biological Chemistry. 2011, May; 286(20): 18066-18078.
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