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  1. 1.   The All of Us Research Program: Data quality, utility, and diversity
  2. Ramirez, Andrea H; Sulieman, Lina; Schlueter, David J; Halvorson, Alese; Qian, Jun; Ratsimbazafy, Francis; Loperena, Roxana; Mayo, Kelsey; Basford, Melissa; Deflaux, Nicole; Muthuraman, Karthik N; Natarajan, Karthik; Kho, Abel; Xu, Hua; Wilkins, Consuelo; Anton-Culver, Hoda; Boerwinkle, Eric; Cicek, Mine; Clark, Cheryl R; Cohn, Elizabeth; Ohno-Machado, Lucila; Schully, Sheri D; Ahmedani, Brian K; Argos, Maria; Cronin, Robert M; O'Donnell, Christopher; Fouad, Mona; Goldstein, David B; Greenland, Philip; Hebbring, Scott J; Karlson, Elizabeth W; Khatri, Parinda; Korf, Bruce; Smoller, Jordan W; Sodeke, Stephen; Wilbanks, John; Hentges, Justin; Mockrin,Stephen; Lunt, Christopher; Devaney, Stephanie A; Gebo, Kelly; Denny, Joshua C; Carroll, Robert J; Glazer, David; Harris, Paul A; Hripcsak, George; Philippakis, Anthony; Roden, Dan M
  3. Patterns (New York, N.Y.). 2022, Aug 12; 3(8): 100570.
  1. 2.   Aligning Tumor Mutational Burden (TMB) quantification across diagnostic platforms: Phase 2 of the Friends of Cancer Research TMB Harmonization Project
  2. Vega, Diana Merino; Yee, Laura M; McShane, Lisa M; Williams,Mickey; Chen,Li; Vilimas, Tomas; Fabrizio, David; Funari, Vincent; Newberg, Justin; Bruce, Lauryn Keeler; Chen, Shu-Jen; Baden, Jonathan; Barrett, J Carl; Beer, Philip; Butler, Matthew; Cheng, Jen-Hao; Conroy, Jeffrey; Cyanam, Dinesh; Eyring, Kenneth; Garcia, Elizabeth; Green, George; Gregersen, Vivi Raundahl; Hellmann, Matthew D; Keefer, Laurel A; Lasiter, Laura; Lazar, Alexander J; Li, Ming-Chung; Macconaill, Laura E; Meier, Kristen; Mellert, Hestia; Pabla, Sarabjot; Pallavajjalla, Aparna; Pestano, Gary; Salgado, Roberto; Samara, Raed; Sokol, Ethan S; Stafford, Phillip; Budczies, Jan; Stenzinger, Albrecht; Tom, Warren; Valkenburg, Kenneth C; Wang, XiaoZhe; Weigman, Victor; Xie, Mingchao; Xie, Qian; Zehir, Ahmet; Zhao, Chen; Zhao, Yingdong; Stewart, Mark D; Allen, Jeff
  3. Annals of oncology : official journal of the European Society for Medical Oncology. 2021, Dec; 32(12): 1626-1636.
  1. 3.   Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine
  2. Kaur, Gurmeet; Evans, David M.; Teicher, Beverly A.; Coussens,Nathan
  3. SLAS Discovery. 2021, Nov 12;
  1. 4.   Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury
  2. Peukert, Konrad; Fox, Mario; Schulz, Susanne; Feuerborn, Caroline; Frede, Stilla; Putensen, Christian; Wrigge, Hermann; Kummerer, Beate Mareike; David, Sascha; Seeliger, Benjamin; Welte, Tobias; Latz, Eicke; Klinman,Dennis; Wilhelm, Christoph; Steinhagen, Folkert; Bode, Christian
  3. American Journal of Respiratory and Critical Care Medicine. 2021, Jul 1; 204(1): 53-63.
  1. 5.   Immunotherapy in sepsis - brake or accelerate?
  2. Steinhagen, Folkert; Schmidt, Susanne; Schewe, Jens-Christian; Peukert, Konrad; Klinman,Dennis; Bode, Christian
  3. Pharmacology & therapeutics. 2020, APR; 208
  1. 6.   Patient-derived orthotopic xenograft models of sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Murakami, Takashi; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Hiroshima, Yukihiko; Higuchi, Takashi; Oshiro, Hiromichi; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer letters. 2020, Jan 28; 469: 332-339.
  1. 7.   Autoinhibition can identify rare driver mutations and advise pharmacology
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020, Jan; 34(1): 16-29.
  1. 8.   Why Are Some Driver Mutations Rare?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Trends in pharmacological sciences. 2019, Dec; 40(12): 919-929.
  1. 9.   AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing
  2. Bhattacharya, Tanmoy; Brettin, Thomas; Doroshow, James H.; Evrard,Yvonne; Greenspan, Emily J.; Gryshuk, Amy L.; Hoang, Thuc T.; Lauzon, Carolyn B. Vea; Nissley,Dwight; Penberthy, Lynne; Stahlberg,Eric; Stevens, Rick; Streitz, Fred; Tourassi, Georgia; Xia, Fangfang; Zaki,George
  3. Frontiers in oncology. 2019, Oct 2; 9
  1. 10.   Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Kiyuna, Tasuku; Tome, Yasunori; Miyake, Kentaro; Murakami, Takashi; Oshiro, Hiromichi; Igarashi, Kentaro; Kawaguchi, Kei; Hsu, John; Singh, Manish; Li, Yunfeng; Nelson, Scott; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4775-4779.
  1. 11.   Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Higuchi, Takashi; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 107-111.
  1. 12.   A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma
  2. Zhang, Zhiying; Hu, Kaiwen; Kiyuna, Tasuko; Miyake, Kentaro; Kawaguchi, Kei; Igarashi, Kentaro; Nelson, Scott D; Li, Yunfeng; Singh, Shree Ram; Hoffman, Robert M
  3. Pharmacological research. 2019, Apr; 142: 169-175.
  1. 13.   Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
  2. Kiyuna, Tasuku; Tome, Yasunori; Murakami, Takashi; Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Miyake, Masuyo; Li, Yunfeng; Nelson, Scott D; Dry, Sarah M; Singh, Arun S; Russell, Tara A; Elliott, Irmina; Singh, Shree Ram; Kanaya, Fuminori; Eilber, Fritz C; Hoffman, Robert M
  3. BMC cancer. 2018, Aug 20; 18(1): 840.
  1. 14.   MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Lwin, Thinzar M; Miyake, Masuyo; Kiyuna, Tasuku; Hwang, Ho Kyoung; Murakami, Takashi; Delong, Jonathan C; Singh, Shree Ram; Clary, Bryan; Bouvet, Michael; Unno, Michiaki; Hoffman, Robert M
  3. Tissue & cell. 2018, Jun; 52: 124-128.
  1. 15.   Recombinant methioninase in combination with DOX overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Li, Shukuan; Han, Qinghong; Tan, Yuying; Murakami, Takashi; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Singh, Arun S; Eckhardt, Mark A; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Tsuchiya, Hiroyuki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Cancer Letters. 2018, MAR 28; 417: 168-173.
  1. 16.   Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas
  2. Hernandez, Belen; Adissu, Hibret A.; Wei, Bih; Michael, Helen T.; Merlino, Glenn; Simpson, R. Mark
  3. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018, FEB; 19
  1. 17.   Lessons from CKD-Related Genetic Association Studies-Moving Forward
  2. Limou, Sophie; Vince, Nicolas; Parsa, Afshin
  3. Clinical journal of the American Society of Nephrology : CJASN. 2018, Jan 6; 13(1): 140-152.
  1. 18.   Nanotechnology as a Delivery Tool for Precision Cancer Therapies
  2. Sharma, Bhawna; Crist, Rachael; Adiseshaiah, Pavan
  3. AAPS Journal. 2017, Nov; 19(6): 1632-1642.
  1. 19.   The promise of Janus kinase inhibitors in the treatment of hematological malignancies
  2. Senkevitch, Emilee; Durum, Scott
  3. Cytokine. 2017, Oct; 98(Special Issue): 33-41.
  1. 20.   Pharmacogenomics Implementation at the National Institutes of Health Clinical Center.
  2. Sissung, Tristan M; McKeeby, Jon W; Patel, Jharana; Lertora, Juan J; Kumar, Parag; Flegel, Willy A; Adams, Sharon D; Eckes, Ellen J; Mickey, Frank; Plona, Teri; Mellott, Stephanie; Baugher, Ryan; Wu, Xiaolin; Soppet, Daniel; Barcus, Mary; Datta, Vivekananda; Pike, Kristen; DiPatrizio, Gary; Figg, William D; Goldspiel, Barry R
  3. Journal of clinical pharmacology. 2017, Oct; 57(Suppl 10): S67-S77.
  1. 21.   Next Generation Sequencing Reveals High Prevalence of BRCA1 and BRCA2 Variants of Unknown Significance in Early-Onset Breast Cancer in African American Women.
  2. Ricks-Santi, Luisel; McDonald, J Tyson; Gold, Bert; Dean, Michael; Thompson, Nicole; Abbas, Muneer; Wilson, Bradford; Kanaan, Yasmine; Naab, Tammey J; Dunston, Georgia
  3. Ethnicity & disease. 2017, Apr 20; 27(2): 169-178.
  1. 22.   Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response
  2. Backman, Joshua D.; O'Connell, Jeffrey R.; Tanner, Keith; Peer, Cody J.; Figg, William D.; Spencer, Shawn D.; Mitchell, Braxton D.; Shuldiner, Alan R.; Yerges-Armstrong, Laura M.; Horenstein, Richard B.; Lewis, Joshua P.
  3. PHARMACOGENETICS AND GENOMICS. 2017, Apr; 27(4): 159-163.
  1. 23.   Targeting KRAS Directly
  2. McCormick, Frank
  3. ANNUAL REVIEW OF CANCER BIOLOGY, VOL 2. 2018; 2 : 81-90.
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