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  1. 1.   Optimized mammalian expression system for the ubiquitin E3 ligase E6AP/UBE3A
  2. Schafer,Annie; Muli,Christine; Heikal,Rehab; Dyba,Marzena; Tarasov,Sergey; Stratton, Margaret M; Strieter, Eric R; Walters,Kylie
  3. Protein Expression and Purification. 2025, Jan 09; 106661.
  1. 2.   Producing recombinant proteins in Vibrio natriegens
  2. Smith,Matthew; Hernández, José Sánchez; Messing,Simon; Ramakrishnan,Nitya; Higgins,Brianna; Mehalko,Jennifer; Perkins,Shelley; Wall,Vanessa; Grose,Carissa; Frank,Peter; Cregger, Julia; Le,Vi; Johnson,Adam; Sherekar, Mukul; Pagonis,Morgan; Drew,Matt; Hong,Min; Widmeyer, Stephanie R T; Denson,John-Paul; Snead,Kelly; Poon,Ivy; Waybright,Tim; Champagne, Allison; Esposito,Dom; Jones,Jane; Taylor,Troy; Gillette,Bill
  3. Microbial Cell Factories. 2024, Jul 24; 23(1): 208.
  1. 3.   Unexpected tobacco etch virus (TEV) protease cleavage of recombinant human proteins
  2. Beaumont,Lauren; Mehalko,Jennifer; Johnson,Adam; Wall,Vanessa; Esposito,Dom
  3. Protein Expression and Purification. 2024, Apr 26; 220: 106488.
  1. 4.   Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Kiyuna, Tasuku; Miyake, Kentaro; Higuchi, Takashi; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2515-2523.
  1. 5.   Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Han, Qinghong; Miyake, Kentaro; Oshiro, Hiromichi; Sugisawa, Norihiko; Tan, Yuying; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2020, FEB 26; 523(1): 135-139.
  1. 6.   Novel EBV LMP-2-affibody and affitoxin in molecular imaging and targeted therapy of nasopharyngeal carcinoma
  2. Zhu, Shanli; Chen, Jun; Xiong, Yirong; Kamara, Saidu; Gu, Meiping; Tang, Wanlin; Chen, Shao; Dong, Haiyan; Xue, Xiangyang; Zheng,Zhi-Ming; Zhang, Lifang
  3. PLoS pathogens. 2020, Jan 06; 16(1): e1008223.
  1. 7.   The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Oshiro, Hiromichi; Han, Qinghong; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Tan, Yuying; Kuchipudi, Shreya; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer chemotherapy and pharmacology. 2019, Nov 08;
  1. 8.   Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Oshiro, Hiromichi; Tome, Yasunori; Kiyuna, Tasuku; Yoon, Sang Nam; Lwin, Thinzar M; Han, Qinghong; Tan, Yuying; Miyake, Kentaro; Higuchi, Takashi; Sugisawa, Norihiko; Katsuya, Yuki; Park, Jun Ho; Zang, Zhiying; Razmjooei, Sahar; Bouvet, Michael; Clary, Bryan; Singh,Shree Ram; Kanaya, Fuminori; Nishida, Kotaro; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4667-4671.
  1. 9.   Vaccine protection against SIVmac239 acquisition
  2. Martins, Mauricio A; Bischof, Georg F; Shin, Young C; Lauer, William A; Gonzalez-Nieto, Lucas; Watkins, David I; Rakasz, Eva G; Lifson, Jeffrey; Desrosiers, Ronald C
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, Jan 29; 116(5): 1739-1744.
  1. 10.   Exogenous Cripto-1 Suppresses Self-Renewal of Cancer Stem Cell Model
  2. Alam, Md Jahangir; Takahashi, Ryota; Afify, Said M.; Oo, Aung Ko Ko; Kumon, Kazuki; Nawara, Hend M.; Khayrani, Aprilliana Cahya; Du, Juan; Zahra, Maram H.; Seno, Akimasa; Salomon, David; Seno, Masaharu
  3. International journal of molecular sciences. 2018, NOV; 19(11):
  1. 11.   Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
  2. Kawaguchi, Kei; Higuchi, Takashi; Li, Shukuan; Han, Qinghong; Tan, Yuying; Igarashi, Kentaro; Zhao, Ming; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Ohshiro, Hiromichi; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Singh, Shree Ram; Eilber, Fritz C; Unno, Michiaki; Hoffman, Robert M
  3. Biochemical and Biophysical Research Communications. 2018, Sep 18; 503(4): 3086-3092.
  1. 12.   Recombinant methioninase in combination with DOX overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Li, Shukuan; Han, Qinghong; Tan, Yuying; Murakami, Takashi; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Singh, Arun S; Eckhardt, Mark A; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Tsuchiya, Hiroyuki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Cancer Letters. 2018, MAR 28; 417: 168-173.
  1. 13.   Biochemical and biological studies of mouse APOBEC3
  2. Nair, S.; Sanchez-Martinez, S.; Ji, X.; Rein, A.
  3. Journal of Virology. 2014, Apr; 88(7): 3850-60.
  1. 14.   Molecular cloning and expression of the IL-10 gene from guinea pigs
  2. Dirisala, V. R.; Jeevan, A.; Bix, G.; Yoshimura, T.; McMurray, D. N.
  3. Gene. 2012, Apr; 498(1): 120-127.
  1. 15.   Attenuation of Neurovirulence, Biodistribution, and Shedding of a Poliovirus:Rhinovirus Chimera after Intrathalamic Inoculation in Macaca fascicularis
  2. Dobrikova, E. Y.; Goetz, C.; Walters, R. W.; Lawson, S. K.; Peggins, J. O.; Muszynski, K.; Ruppel, S.; Poole, K.; Giardina, S. L.; Vela, E. M.; Estep, J. E.; Gromeier, M.
  3. Journal of Virology. 2012, Mar; 86(5): 2750-2759.
  1. 16.   An overview of enzymatic reagents for the removal of affinity tags
  2. Waugh, D. S.
  3. Protein Expression and Purification. 2011, Dec; 80(2): 283-293.
  1. 17.   Hyperthermia-triggered intracellular delivery of anticancer agent to HER2(+) cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2(+) affisomes)
  2. Smith, B.; Lyakhov, I.; Loomis, K.; Needle, D.; Baxa, U.; Yavlovich, A.; Capala, J.; Blumenthal, R.; Puri, A.
  3. Journal of Controlled Release. 2011, Jul; 153(2): 187-194.
  1. 18.   Antifungal activity of recombinant mouse beta-defensin 3
  2. Jiang, Y.; Wang, Y.; Wang, B.; Yang, D.; Yu, K.; Yang, X.; Liu, F.; Jiang, Z.; Li, M.
  3. Letters in Applied Microbiology. 2010, May; 50(5): 468-473.
  1. 19.   Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coil
  2. Pasek, M.; Boeggeman, E.; Ramakrishnan, B.; Qasba, P. K.
  3. Biochemical and Biophysical Research Communications. 2010, Apr; 394(3): 679-684.
  1. 20.   Refined methods for propagating vesicular stomatitis virus vectors that are defective for G protein expression
  2. Witko, S. E.; Johnson, J. E.; Kalyan, N. K.; Felber, B. K.; Pavlakis, G. N.; Sidhu, M. K.; Hendry, R. M.; Udem, S. A.; Parks, C. L.
  3. Journal of Virological Methods. 2010, Mar; 164(1-2): 43-50.
  1. 21.   Coexpression of IL-18 Strongly Attenuates IL-12-Induced Systemic Toxicity through a Rapid Induction of IL-10 without Affecting its Antitumor Capacity
  2. Rodriguez-Galan, M. C.; Reynolds, D.; Correa, S. G.; Iribarren, P.; Watanabe, M.; Young, H. A.
  3. Journal of Immunology. 2009, Jul; 183(1): 740-748.
  1. 22.   Characterization of a chimeric monoclonal antibody against the insulin-like growth factor-I receptor
  2. Zhang, M. Y.; Feng, Y.; Wang, Y.; Dimitrov, D. S.
  3. Mabs. 2009, Sep-Oct; 1(5): 475-80.
  1. 23.   Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5
  2. Abe, S.; Okuda, K.; Ura, T.; Kondo, A.; Yoshida, A.; Yoshizaki, S.; Mizuguchi, H.; Klinman, D.; Shimada, M.
  3. Journal of Gene Medicine. 2009 11(7): 570-579.
  1. 24.   Serological Diagnosis of Human Herpes Simplex Virus Type 1 and 2 Infections by Luciferase Immunoprecipitation System Assay
  2. Burbelo, P. D.; Hoshino, Y.; Leahy, H.; Krogmann, T.; Hornung, R. L.; Iadarola, M. J.; Cohen, J. I.
  3. Clinical and Vaccine Immunology. 2009 16(3): 366-371.
  1. 25.   Preparation of recombinant HIV-1 gag protein and assembly of virus-like particles in vitro
  2. Datta, S. A.; Rein, A.
  3. Methods in molecular biology (Clifton, N.J.). 2009 485: 197-208.
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