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  1. 1.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 2.   Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions
  2. Lam, Norris; Finney, Richard; Yang, Shicheng; Choi, Stephanie; Wu,Xiaolin; Cutmore, Lauren; Andrade, Jorge; Huang, Lei; Amatya, Christina; Cam, Margaret; Kochenderfer, James N
  3. Molecular Therapy Oncolytics. 2023, Sep 21; 30: 132-149.
  1. 3.   Recombineering: Genetic Engineering in Escherichia coli Using Homologous Recombination
  2. Thomason,Lynn; Costantino, Nina; Li, Xintian; Court,Don
  3. Current Protocols. 2023, Feb; 3(2): e656.
  1. 4.   Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans
  2. Bashirova,Arman; Kasprzak,Wojciech; Ohuigin,Colm; Carrington,Mary
  3. Immunogenetics. 2022, Nov 30;
  1. 5.   Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication
  2. Rawson, Jonathan M O; Nikolaitchik,Olga; Yoo, Jennifer A; Somoulay, Xayathed; Brown, Matthew A; Mbuntcha Bogni, Franck S; Pathak,Vinay; Soheilian,Ferri; Slack, Ryan L; Sarafianos, Stefan G; Hu,Wei-Shau
  3. mBio. 2022, Aug 29; e0222022.
  1. 6.   WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells
  2. Datta, Arindam; Biswas, Kajal; Sommers, Joshua A.; Thompson, Haley; Awate, Sanket; Nicolae, Claudia M.; Thakar, Tanay; Moldovan, George-Lucian; Shoemaker, Robert H.; Sharan, Shyam K.; Brosh, Robert M.
  3. Nature Communications. 2021, Nov 12; 12(1):
  1. 7.   The dystonia gene THAP1 controls DNA double-strand break repair choice
  2. Shinoda, Kenta; Zong, Dali; Callen, Elsa; Wu, Wei; Dumitrache, Lavinia C.; Belinky, Frida; Chari,Raj; Wong, Nancy; Ishikawa, Momoko; Stanlie, Andre; Multhaupt-Buell, Trisha; Sharma, Nutan; Ozelius, Laurie; Ehrlich, Michelle; McKinnon, Peter J.; Nussenzweig, Andre
  3. MOLECULAR CELL. 2021, Jun 17; 81(12): 2611-2624.e10.
  1. 8.   A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome
  2. Mun, Seyoung; Kim, Songmi; Lee, Wooseok; Kang, Keunsoo; Meyer,Thomas; Han, Bok-Ghee; Han, Kyudong; Kim, Heui-Soo
  3. Experimental and Molecular Medicine. 2021, Apr; 53(4): 615-630.
  1. 9.   Virus Evolution and Neutralization Sensitivity in an HIV-1 Subtype B ' Infected Plasma Donor with Broadly Neutralizing Activity
  2. Hu, Yuanyuan; Zou, Sen; Wang, Zheng; Liu, Ying; Ren, Li; Hao, Yanling; Sun, Shasha; Hu, Xintao; Ruan, Yuhua; Ma, Liying; Shao, Yiming; Hong, Kunxue
  3. Vaccines. 2021, Apr; 9(4):
  1. 10.   A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
  2. Biswas,Kajal; Lipton, Gary B; Stauffer,Stacey; Sullivan,Teresa; Cleveland, Linda; Southon,Eileen; Reid,Susan; Magidson,Valentin; Iversen, Edwin S; Sharan,Shyam
  3. NPJ genomic medicine. 2020, Dec 08; 5(1): 52.
  1. 11.   Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination
  2. He,Yafeng; Ren,Jianke; Xu,Xiaoping; Ni,Kai; Schwader, Andrew; Finney, Richard; Wang, Can; Sun, Lei; Klarmann, Kimberly; Keller,Jonathan; Tubbs, Anthony; Nussenzweig, Andre; Muegge, Kathrin
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, AUG 18; 117(33): 20100-20108.
  1. 12.   Dual infection and recombination of Kaposi sarcoma herpesvirus revealed by whole-genome sequence analysis of effusion samples
  2. Cornejo Castro,Elena; Marshall,Vickie; Lack,Justin; Lurain, Kathryn; Immonen,Taina; Labo,Nazzarena; Fisher, Nicholas C; Ramaswami, Ramya; Polizzotto, Mark N; Keele,Brandon; Yarchoan, Robert; Uldrick, Thomas S; Whitby,Denise
  3. Virus Evolution. 2020, Jul; 6(2): veaa047.
  1. 13.   An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses
  2. Wells,Daria; Guo,Amber; Shao,Wei; Bale,Michael; Coffin, John M; Hughes,Stephen; Wu,Xiaolin
  3. BMC genomics. 2020, Mar 09; 21(1): 216.
  1. 14.   Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18)
  2. Hagan, Andrew S; Boylan,Michael; Smith, Craig; Perez-Santamarina, Estela; Kowalska, Karolina; Hung, Irene H; Lewis, Renate M; Hajihosseini, Mohammad K; Lewandoski,Mark; Ornitz, David M
  3. Developmental dynamics : an official publication of the American Association of Anatomists. 2019, JUL 22;
  1. 15.   Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers
  2. Wilsker,Deborah; Barrett, Allison M.; Dull,Angie; Lawrence,Scott; Hollingshead,Melinda; Chen, Alice; Kummar, Shivaani; Parchment,Ralph; Doroshow, James H.; Kinders,Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, MAY 15; 25(10): 3084-3095.
  1. 16.   Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells
  2. Guenther, Kacey L.; Cheruku, Patali S.; Cash, Ayla; Smith, Richard H.; Alvarado, Luigi J.; Burkett,Sandra; Townsley, Danielle M.; Winkler, Thomas; Larochelle, Andre
  3. Experimental hematology. 2019, May; 73: 1-6.
  1. 17.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 18.   Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity
  2. Rawson,Jonathan; Nikolaitchik,Olga; Keele,Brandon; Pathak,Vinay; Hu,Wei-Shau
  3. NUCLEIC ACIDS RESEARCH. 2018, Nov 16; 46(20): 10535-10545.
  1. 19.   Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase
  2. Hickman, Alison B.; Voth, Andrea; Ewis, Hosam; Li, Xianghong; Craig, Nancy L.; Dyda, Fred
  3. NUCLEIC ACIDS RESEARCH. 2018, NOV 2; 46(19): 10286-10301.
  1. 20.   SpTransformer proteins from the purple sea urchin opsonize bacteria, augment phagocytosis, and retard bacterial growth
  2. Chou, Hung-Yen; Lun, Cheng Man; Smith, L. Courtney
  3. PloS One. 2018, May 8; 13(5): e0196890.
  1. 21.   Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis
  2. Cissé, Ousmane H; Ma, Liang; Wei Huang, Da; Khil, Pavel P; Dekker, John P; Kutty, Geetha; Bishop, Lisa; Liu, Yueqin; Deng, Xilong; Hauser, Philippe M; Pagni, Marco; Hirsch, Vanessa; Lempicki, Richard A; Stajich, Jason E; Cuomo, Christina A; Kovacs, Joseph A
  3. mBio. 2018, May-Jun; 9(3): pii: e00381-18.
  1. 22.   RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
  2. Dungrawala, Huzefa; Bhat, Kamakoti P; Le Meur, Rémy; Chazin, Walter J; Ding, Xia; Sharan, Shyam; Wessel, Sarah R; Sathe, Aditya A; Zhao, Runxiang; Cortez, David
  3. Molecular cell. 2017, Aug 3; 67(3): 374-+.
  1. 23.   Going in the Right Direction: Mating-Type Switching of Schizosaccharomyces pombe Is Controlled by Judicious Expression of Two Different swi2 Transcripts
  2. Yu, C. H.; Bonaduce, M. J.; Klar, A. J. S.
  3. Genetics. 2012, Mar; 190(3): 977-U182.
  1. 24.   Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway
  2. Zhu, J. J.; Nguyen, M. T.; Nakamura, E.; Yang, J. M.; Mackem, S.
  3. Genesis. 2012, Feb; 50(2): 102-111.
  1. 25.   A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3
  2. Garcia-Closas, M.; Ye, Y. Q.; Rothman, N.; Figueroa, J. D.; Malats, N.; Dinney, C. P.; Chatterjee, N.; Prokunina-Olsson, L.; Wang, Z. M.; Lin, J.; Real, F. X.; Jacobs, K. B.; Baris, D.; Thun, M.; De Vivo, I.; Albanes, D.; Purdue, M. P.; Kogevinas, M.; Kamat, A. M.; Lerner, S. P.; Grossman, H. B.; Gu, J.; Pu, X.; Hutchinson, A.; Fu, Y. P.; Burdett, L.; Yeager, M.; Tang, W.; Tardon, A.; Serra, C.; Carrato, A.; Garcia-Closas, R.; Lloreta, J.; Johnson, A.; Schwenn, M.; Karagas, M. R.; Schned, A.; Andriole, G.; Grubb, R.; Black, A.; Jacobs, E. J.; Diver, W. R.; Gapstur, S. M.; Weinstein, S. J.; Virtamo, J.; Hunter, D. J.; Caporaso, N.; Landi, M. T.; Fraumeni, J. F.; Silverman, D. T.; Chanock, S. J.; Wu, X. F.
  3. Human Molecular Genetics. 2011, Nov; 20(21): 4282-4289.
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