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  1. 1.   Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor
  2. Xu, X.; Hou, Y.; Yin, X. Y.; Bao, L.; Tang, A. F.; Song, L. T.; Li, F. Q.; Tsang, S.; Wu, K.; Wu, H. J.; He, W. M.; Zeng, L.; Xing, M. J.; Wu, R. H.; Jiang, H.; Liu, X.; Cao, D. D.; Guo, G. W.; Hu, X. D.; Gui, Y. T.; Li, Z. S.; Xie, W. Y.; Sun, X. J.; Shi, M.; Cai, Z. M.; Wang, B.; Zhong, M. M.; Li, J. X.; Lu, Z. H.; Gu, N.; Zhang, X. Q.; Goodman, L.; Bolund, L.; Wang, J.; Yang, H. M.; Kristiansen, K.; Dean, M.; Li, Y. R.
  3. Cell. 2012, Mar; 148(5): 886-895.
  1. 2.   Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
  2. Gui, Y. T.; Guo, G. W.; Huang, Y.; Hu, X. D.; Tang, A. F.; Gao, S. J.; Wu, R. H.; Chen, C.; Li, X. X.; Zhou, L.; He, M. H.; Li, Z. S.; Sun, X. J.; Jia, W. L.; Chen, J. N.; Yang, S. M.; Zhou, F. J.; Zhao, X. K.; Wan, S. Q.; Ye, R.; Liang, C. Z.; Liu, Z. S.; Huang, P. D.; Liu, C. X.; Jiang, H.; Wang, Y.; Zheng, H. C.; Sun, L.; Liu, X. W.; Jiang, Z. M.; Feng, D. F.; Chen, J.; Wu, S.; Zou, J.; Zhang, Z. F.; Yang, R. L.; Zhao, J.; Xu, C. J.; Yin, W. H.; Guan, Z. C.; Ye, J. X.; Zhang, H.; Li, J. X.; Kristiansen, K.; Nickerson, M. L.; Theodorescu, D.; Li, Y. R.; Zhang, X. Q.; Li, S. G.; Wang, J.; Yang, H. M.; Cai, Z. M.
  3. Nature Genetics. 2011, Sep; 43(9): 875-U84.
  1. 3.   Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
  2. Baba, M.; Furihata, M.; Hong, S. B.; Tessarollo, L.; Haines, D. C.; Southon, E.; Patel, V.; Igarashi, P.; Alvord, W. G.; Leighty, R.; Yao, M.; Bernardo, M.; Ileva, L.; Choyke, P.; Warren, M. B.; Zbar, B.; Linehan, W. M.; Schmidt, L. S.
  3. Journal of the National Cancer Institute. 2008 100(2): 140-154.
  1. 4.   Identification and characterization of a novel folliculin-interacting protein FNIP2
  2. Hasumi, H.; Baba, M.; Hong, S. B.; Hasumi, Y.; Huang, Y.; Yao, M.; Valera, V. A.; Linehan, W. M.; Schmidt, L. S.
  3. Gene. 2008 415(1-2): 60-67.
  1. 5.   Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
  2. Linehan, W. M.; Pinto, P. A.; Srinivasan, R.; Merino, M.; Choyke, P.; Choyke, L.; Coleman, J.; Toro, J.; Glenn, G.; Vocke, C.; Zbar, B.; Schmidt, L. S.; Bottaro, D.; Neckers, L.
  3. Clinical Cancer Research. 2007, Jan; 13(2): 671S-679S.
  1. 6.   Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression
  2. Woldemichael, G. M.; Vasselli, J. R.; Gardella, R. S.; McKee, T. C.; Linehan, W. M.; McMahon, J. B.
  3. Journal of Biomolecular Screening. 2006, Sep; 11(6): 678-687.
  1. 7.   The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest
  2. Nagl, N. G.; Patsialou, A.; Haines, D. S.; Dallas, P. B.; Beck, G. R.; Moran, E.
  3. Cancer Research. 2005, OCT 15; 65(20): 9236-9244.
  1. 8.   STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker
  2. Ivanova, A.; Liao, S. Y.; Lerman, M. I.; Ivanov, S.; Stanbridge, E. J.
  3. Journal of Medical Genetics. 2005, JUL; 42(7): 565-576.
  1. 9.   High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dube-associated renal tumors
  2. Vocke, C. D.; Yang, Y. F.; Pavlovich, C. P.; Schmidt, L. S.; Nickerson, M. L.; Torres-Cabala, C. A.; Merino, M. J.; Walther, M. M.; Zbar, B.; Linehan, W. M.
  3. Journal of the National Cancer Institute. 2005, JUN 15; 97(12): 931-935.
  1. 10.   Constitutive expression of functional CD40 on mouse renal cancer cells: Induction of Fas and Fas-mediated killing by CD40L
  2. Lee, J. K.; Seki, N.; Sayers, T. J.; Subleski, J.; Gruys, E. M.; Murphy, W. J.; Wiltrout, R. H.
  3. Cellular Immunology. 2005, JUN; 235(2): 145-152.
  1. 11.   Reduction of the antiapoptotic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis
  2. Brooks, A. D.; Sayers, T. J.
  3. Cancer Immunology Immunotherapy. 2005, MAY; 54(5): 499-505.
  1. 12.   Evaluation and management of renal tumors in the Birt-Hogg-Dube syndrome
  2. Pavlovich, C. P.; Grubb, R. L.; Hurley, K.; Glenn, G. M.; Toro, J.; Schmidt, L. S.; Torres-Cabala, C.; Merino, M. J.; Zbar, B.; Choyke, P.; Walther, M. M.; Linehan, W. M.
  3. Journal of Urology. 2005, MAY; 173(5): 1482-1486.
  1. 13.   Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
  2. Graveel, C.; Su, Y. L.; Koeman, J.; Wang, L. M.; Tessarollo, L.; Fiscella, M.; Birchmeier, C.; Swiatek, P.; Bronson, R.; Woude, G. V.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2004, DEC 7; 101(49): 17198-17203.
  1. 14.   Birt-Hogg-Dube syndrome, a genodermatosis that increases risk for renal carcinoma
  2. Schmidt, L. S.
  3. Current Molecular Medicine. 2004, DEC; 4(8): 877-885.
  1. 15.   Early onset hereditary papillary renal carcinoma: Germline missense mutations in the tyrosine kinase domain of the met proto-oncogene
  2. Schmidt, L. S.; Nickerson, M. L.; Angeloni, D.; Glenn, G. M.; Walther, M. M.; Albert, P. S.; Warren, M. B.; Choyke, P. L.; Torres-Cabala, C. A.; Merino, M. J.; Brunet, J.; Berez, V.; Borras, J.; Sesia, G.; Middelton, L.; Phillips, J. L.; Stolle, C.; Zbar, B.; Pautler, S. E.; Linehan, W. M.
  3. Journal of Urology. 2004, OCT; 172(4): 1256-1261.
  1. 16.   Genetic basis of cancer of the kidney: Disease specific approaches to therapy
  2. Linehan, W. M.; Vasselli, J.; Srinivasan, R.; Walther, M. M.; Merino, M.; Choyke, P.; Vocke, C.; Schmidt, L.; Isaacs, J. S.; Glenn, G.; Toro, J.; Zbar, B.; Bottaro, D.; Neckers, L.
  3. Clinical Cancer Research. 2004, SEP 15; 10(18, Part 2 Suppl. S): 6282S-6289S.
  1. 17.   Sensitivity of renal cell carcinoma to aminoflavone: Role of CYP1A1
  2. Loaiza-Perez, A. I.; Kenney, S.; Boswell, J.; Hollingshead, M.; Hose, C.; Linehan, W. M.; Worrell, R.; Rubinstein, L.; Sausville, A.; Vistica, D. T.
  3. Journal of Urology. 2004 171(4): 1688-1697.
  1. 18.   A germ-line insertion in the Birt-Hogg-Dube (BHD) gene gives rise to the Nihon rat model of inherited renal cancer
  2. Okimoto, K.; Sakurai, J.; Kobayashi, T.; Mitani, H.; Hirayama, Y.; Nickerson, M. L.; Warren, M. B.; Zbar, B.; Schmidt, L. S.; Hino, O.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2004 101(7): 2023-2027.
  1. 19.   Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter
  2. Zatyka, M.; Morrissey, C.; Kuzmin, I.; Lerman, M. I.; Latif, F.; Richards, F. M.; Maher, E. R.
  3. Journal of Medical Genetics. 2002 39(7): 463-472.
  1. 20.   Analysis of aberrant methylation of the VHL gene by transgenes, monochromosome transfer, and cell fusion
  2. Kuzmin, I.; Geil, L.; Ge, H. Y.; Bengtsson, U.; Duh, F. M.; Stanbridge, E. J.; Lerman, M. I.
  3. Oncogene. 1999 18(41): 5672-5679.
  1. 21.   Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein
  2. Lee, S.; Neumann, M.; Stearman, R.; Stauber, R.; Pause, A.; Pavlakis, G. N.; Klausner, R. D.
  3. Molecular and Cellular Biology. 1999 19(2): 1486-1497.
  1. 22.   Expression of von Hippel-Lindau protein in normal and pathological human tissues
  2. Sakashita, N.; Takeya, M.; Kishida, T.; Stackhouse, T. M.; Zbar, B.; Takahashi, K.
  3. Histochemical Journal. 1999 31(2): 133-144.
  1. 23.   Intradermal delivery of IL-12 naked DNA induces systemic NK cell activation and Th1 response in vivo that is independent of endogenous IL-12 production
  2. Watanabe, M.; Fenton, R. G.; Wigginton, J. M.; McCormick, K. L.; Volker, K. F.; Fogler, W. E.; Roessler, P. G.; Wiltrout, R. H.
  3. Journal of Immunology. 1999 163(4): 1943-1950.
  1. 24.   Loss of Heterozygosity and Somatic Mutations of the Vhl Tumor Suppressor Gene in Sporadic Cerebellar Hemangioblastomas
  2. Lee, J. Y.; Dong, S. M.; Park, W. S.; Yoo, N. J.; Kim, C. S.; Jang, J. J.; Chi, J. G.; Zbar, B.; Lubensky, I. A.; Linehan, W. M.; Vortmeyer, A. O.; Zhuang, Z. P.
  3. Cancer Research. 1998 58(3): 504-508.
  1. 25.   T Cell- and Nk Cell-Independent Inhibition of Hepatic Metastases By Systemic Administration of an Il-12-Expressing Recombinant Adenovirus
  2. Siders, W. M.; Wright, P. W.; Hixon, J. A.; Alvord, W. G.; Back, T. C.; Wiltrout, R. H.; Fenton, R. G.
  3. Journal of Immunology. 1998 160(11): 5465-5474.
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