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  1. 1.   Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
  2. Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S; Cho, May; Davis, Elizabeth J; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das,Bishu; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; LoRusso, Patricia M
  3. Cancer. 2025, Feb 15; 131(4): e35755.
  1. 2.   Longitudinal analysis of the lung proteome reveals persistent repair months after mild to moderate COVID-19
  2. Kanth, Shreya M; Huapaya, Julio A; Gairhe, Salina; Wang, Honghui; Tian, Xin; Demirkale, Cumhur Y; Hou, Chunyan; Ma, Junfeng; Kuhns,Doug; Fink,Dani; Malayeri, Ashkan; Turkbey, Evrim; Harmon, Stephanie A; Chen, Marcus Y; Regenold, David; Lynch, Nicolas F; Ramelli, Sabrina; Li, Willy; Krack, Janell; Kuruppu, Janaki; Lionakis, Michail S; Strich, Jeffrey R; Davey, Richard; Childs, Richard; Chertow, Daniel S; Kovacs, Joseph A; Parizi, Parizad Torabi-; Suffredini, Anthony F
  3. Cell Reports. Medicine. 2024, Jul 16; 5(7): 101642.
  1. 3.   Olaparib for childhood tumors harboring defects in DNA damage repair genes: arm H of the NCI-COG Pediatric MATCH trial
  2. Glade Bender, Julia L; Pinkney, Kerice; Williams,Mickey; Roy-Chowdhuri, Sinchita; Patton, David R; Coffey, Brent D; Reid, Joel M; Piao, Jin; Saguilig, Lauren; Alonzo, Todd A; Berg, Stacey L; Ramirez, Nilsa C; Fox, Elizabeth; Weigel, Brenda J; Hawkins, Douglas S; Mooney, Margaret M; Takebe, Naoko; Tricoli, James V; Janeway, Katherine A; Seibel, Nita L; Parsons, Donald W
  3. The Oncologist. 2024, May 30;
  1. 4.   Mismatch repair protein MLH1 suppresses replicative stress in BRCA2 deficient breast tumors
  2. Sengodan,Satheesh; Hu, Xiaoju; Peddibhotla, Vaishnavi; Balamurugan, Kuppusamy; Mitrophanov,Alex; McKennett,Lois; Kharat, Suhas S; Sanawar, Rahul; Singh, Vinod Kumar; Albaugh,Mary; Burkett,Sandra; Zhao,Yongmei; Tran,Bao; Malys,Tyler; Sterneck,Esta; De, Subhajyoti; Sharan,Shyam
  3. The Journal of Clinical Investigation. 2024, Jan 25; 134(7):
  1. 5.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 6.   Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
  2. Biswas,Kajal; Mitrophanov,Alex; Sahu,Sounak; Sullivan,Teresa; Southon,Eileen; Nousome,Darryl; Reid, Susan; Narula, Sakshi; Smolen, Julia; Sengupta, Trisha; Riedel-Topper, Maximilian; Kapoor, Medha; Babbar, Anav; Stauffer,Stacey; Cleveland, Linda; Tandon, Mayank; Malys,Tyler; Sharan,Shyam
  3. Cell Reports Methods. 2023, Nov 20; 3(11): 100628.
  1. 7.   1H, 15N, 13C resonance assignments for proteasome shuttle factor hHR23a
  2. Chen,Xiang; Walters,Kylie
  3. Biomolecular NMR Assignments. 2023, Oct 09;
  1. 8.   Partial deletions of the autoregulatory C-terminal domain of Artemis and their effect on its nuclease activity
  2. Anne-Esguerra, Z; Wu, Mousheng; Watanabe, Go; Flint,Andrew; Lieber, Michael R
  3. DNA Repair. 2022, Oct 28; 120: 103422.
  1. 9.   CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes
  2. Brault, Julie; Liu, Taylor; Bello, Ezekiel; Liu, Siyuan; Sweeney, Colin L.; Meis, Ronald J.; Koontz, Sherry; Corsino, Cristina; Choi, Uimook; Vayssiere, Guillaume; Bosticardo, Marita; Dowdell, Kennichi; Lazzarotto, Cicera R.; Clark, Aaron B.; Notarangelo, Luigi D.; Ravell, Juan C.; Lenardo, Michael J.; Kleinstiver, Benjamin P.; Tsai, Shengdar Q.; Wu, Xiaolin; Dahl, Gary A.; Malech, Harry L.; De Ravin, Suk See
  3. Blood. 2021, Dec 30; 138(26): 2768-2780.
  1. 10.   WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells
  2. Datta, Arindam; Biswas, Kajal; Sommers, Joshua A.; Thompson, Haley; Awate, Sanket; Nicolae, Claudia M.; Thakar, Tanay; Moldovan, George-Lucian; Shoemaker, Robert H.; Sharan, Shyam K.; Brosh, Robert M.
  3. Nature Communications. 2021, Nov 12; 12(1):
  1. 11.   The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
  2. Xu,Xiaoping; Ni, Kai; He,Yafeng; Ren, Jianke; Sun, Chongkui; Liu, Yie; Aladjem, Mirit; Burkett, Sandra; Finney, Richard; Ding, Xia; Sharan,Shyam; Muegge,Kathrin
  3. Nature communications. 2021, Jun 10; 12(1):
  1. 12.   Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment
  2. Wheeler, David A; Takebe, Naoko; Hinoue, Toshinori; Hoadley, Katherine A; Cardenas, Maria F; Hamilton, Alina M; Laird, Peter W; Wang, Linghua; Johnson, Adrienne; Dewal, Ninad; Miller, Vincent; Piñeyro, David; Castro de Moura, Manuel; Esteller, Manel; Shen, Hui; Zenklusen, Jean Claude; Tarnuzzer, Roy; McShane, Lisa M; Tricoli, James V; Williams, Paul M; Lubensky, Irina; O'Sullivan-Coyne, Geraldine; Kohn, Elise C; Little, Richard F; White, Jeffrey; Malik, Shakun; Harris, Lyndsay; Weil, Carol; Chen, Alice P; Karlovich,Chris; Rodgers, Brian; Shankar, Lalitha; Jacobs, Paula; Nolan, Tracy; Hu, Jianhong; Muzny, Donna M; Doddapaneni, Harshavardhan; Korchina, Viktoriya; Gastier-Foster, Julie; Bowen, Jay; Leraas, Kristen; Edmondson,Elijah; Doroshow, James H; Conley, Barbara A; Ivy, S Percy; Staudt, Louis M
  3. Cancer Cell. 2021, Jan 11; 39(1): 38-53.e7.
  1. 13.   Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
  2. Tang, Liu-Ya; Thomas, Adam; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2020, Dec 25; 295(52): 18485-18493.
  1. 14.   An RNA Repair Operon Regulated by Damaged tRNAs
  2. Hughes,Kevin; Chen,Xinguo; Burroughs, A Maxwell; Aravind, L; Wolin,Sandra
  3. Cell reports. 2020, Dec 22; 33(12): 108527.
  1. 15.   A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
  2. Biswas,Kajal; Lipton, Gary B; Stauffer,Stacey; Sullivan,Teresa; Cleveland, Linda; Southon,Eileen; Reid,Susan; Magidson,Valentin; Iversen, Edwin S; Sharan,Shyam
  3. NPJ genomic medicine. 2020, Dec 08; 5(1): 52.
  1. 16.   Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains
  2. Rawi, Reda; Rutten, Lucy; Lai, Yen-Ting; Olia, Adam S; Blokland, Sven; Juraszek, Jarek; Shen, Chen-Hsiang; Tsybovsky,Yaroslav; Verardi, Raffaello; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Chuang, Gwo-Yu; Kwong, Peter D; Langedijk, Johannes P M
  3. Cell reports. 2020, Nov 24; 33(8): 108432.
  1. 17.   Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas
  2. Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Meehan, Robert S; Do, Khanh; Collins, Jerry M; Anderson, Larry; Ishii, Kazusa; Takebe, Naoko; Zlott, Jennifer; Juwara,Lamin; Piekarz, Richard; Streicher, Howard; Sharon, Elad; Rubinstein, Larry; Voth,Andrea; Lozier, Jay; Dull,Angie; Wilsker,Deborah; Hinoue, Toshinori; Laird, Peter W; Ferry-Galow,Katherine; Kinders,Robert; Parchment,Ralph; Doroshow,Jim; Chen, Alice P
  3. Oncotarget. 2020, Nov 03; 11(44): 3959-3971.
  1. 18.   Blood RNA Integrity is a Direct and Simple Reporter of Radiation Exposure and Prognosis: A Pilot Study
  2. Alkhalil, Abdulnaser; Clifford, John L; Ball, Robert; Day, Anna; Chan, Rossana; Carney, Bonnie C; Miller, Stacy Ann; Campbell, Ross; Kumar, Raina; Gautam, Aarti; Hammamieh, Rasha; Moffatt, Lauren T; Shupp, Jeffrey W
  3. Radiation research. 2020, JUN; 193(6): 543-551.
  1. 19.   Tumour predisposition and cancer syndromes as models to study gene-environment interactions
  2. Carbone, Michele; Arron, Sarah T.; Beutler, Bruce; Bononi, Angela; Cavenee, Webster; Cleaver, James E.; Croce, Carlo M.; D'Andrea, Alan; Foulke, William D.; Gaudino, Giovanni; Groden, Joanna L.; Henske, Elizabeth P.; Hickson, Ian D.; Hwang, Paul M.; Kolodner, Richard D.; Mak, Tak W.; Malkin, David; Monnat, Raymond J. Jr Jr; Novelli, Flavia; Pass, Harvey; Petrini, John H.; Schmidt,Laura; Yang, Haining
  3. Nature reviews. Cancer. 2020, May 29;
  1. 20.   SL-BioDP: Multi-Cancer Interactive Tool for Prediction of Synthetic Lethality and Response to Cancer Treatment
  2. Deng,Xiang; Das, Shaoli; Valdez,Kristin; Camphausen, Kevin; Shankavaram, Uma
  3. Cancers. 2019, Nov; 11(11): pii: E1682.
  1. 21.   Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
  2. Khil, Pavel P; Dulanto Chiang, Augusto; Ho, Jonathan; Youn, Jung-Ho; Lemon, Jamie K; Gea-Banacloche, Juan; Frank, Karen M; Parta,Mark; Bonomo, Robert A; Dekker, John P
  3. mBio. 2019, Sep; 10(5): pii: e01822-19.
  1. 22.   Durvalumab in Combination with Olaparib in Patients with Relapsed Small Cell Lung Cancer: Results from a Phase II Study
  2. Thomas, Anish; Vilimas, Rasa; Trindade, Christopher; Erwin-Cohen,Rebecca; Roper, Nitin; Xi, Liqiang; Krishnasamy, Venkatesh; Levy, Elliot; Mammen, Andy; Nichols, Samantha; Chen, Yuanbin; Velcheti, Vamsidhar; Yin, Faye; Szabo, Eva; Pommier, Yves; Steinberg, Seth M; Trepel, Jane B; Raffeld, Mark; Young,Howard; Khan, Javed; Hewitt, Stephen; Lee, Jung-Min
  3. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2019, AUG; 14(8): 1447-1457.
  1. 23.   Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells
  2. Guenther, Kacey L.; Cheruku, Patali S.; Cash, Ayla; Smith, Richard H.; Alvarado, Luigi J.; Burkett,Sandra; Townsley, Danielle M.; Winkler, Thomas; Larochelle, Andre
  3. Experimental hematology. 2019, May; 73: 1-6.
  1. 24.   Label-free mesenchymal stem cell enrichment from bone marrow samples by inertial microfluidics
  2. Lee, Lap Man; Rosano, Jenna M.; Wang, Yi; Klarmann, George J.; Garson, Charles J.; Prabhakarpandian, Balabhaskar; Pant, Kapil; Alvarez, Luis M.; Lai, Eva
  3. ANALYTICAL METHODS. 2018, Feb 21; 10(7): 713-721.
  1. 25.   Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
  2. Kim, Jeongkyu; Sturgill, David; Sebastian, Robin; Khurana, Simran; Tran, Andy D; Edwards, Garrett B; Kruswick, Alex; Burkett, Sandra; Hosogane, Eri K; Hannon, William W; Weyemi, Urbain; Bonner, William M; Luger, Karolin; Oberdoerffer, Philipp
  3. Molecular Cell. 2018, Jan 4; 69(1): 36-47.
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