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  1. 1.   Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir
  2. Briganti, Lorenzo; Annamalai, Arun S; Bester, Stephanie M; Wei, Guochao; Andino-Moncada, Jonathan R; Singh, Satya P; Kleinpeter,Alexander; Tripathi, Meghna; Nguyen, Binh; Radhakrishnan, Rajalingam; Singh, Parmit K; Greenwood, Juliet; Schope, Lauren I; Haney, Reed; Huang, Szu-Wei; Freed, Eric O; Engelman, Alan N; Francis, Ashwanth C; Kvaratskhelia, Mamuka
  3. mBio. 2025, Apr 15; e0361324.
  1. 2.   TRa1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility
  2. Edmondson,Elijah; Kimura, Takahito; Hwang, Eunmi; Kim, Minjun; Warner,Andrew; Zhu, Yuelin; Zhao, Li; Yu, Yanlin; Zhu, Xuguang; Hernandez, Maria; Kedei, Noemi; Cheng, Sheue-Yann
  3. Scientific Reports. 2025, Jan 31; 15(1): 3892.
  1. 3.   Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
  2. Smith,Steven; Zhao,Xuezhi; Hughes,Stephen; Burke,Terrence
  3. Viruses. 2025, Jan 16; 17(1):
  1. 4.   Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2
  2. Hattori, Shin-Ichiro; Bulut, Haydar; Hayashi, Hironori; Kishimoto, Naoki; Takamune, Nobutoki; Hasegawa, Kazuya; Furusawa, Yuri; Yamayoshi, Seiya; Murayama, Kazutaka; Tamamura, Hirokazu; Li,Mi; Wlodawer, Alexander; Kawaoka, Yoshihiro; Misumi, Shogo; Mitsuya, Hiroaki
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Sep 10; 121(37): e2404175121.
  1. 5.   Insights into gemcitabine resistance in pancreatic cancer: association with metabolic reprogramming and TP53 pathogenicity in patient derived xenografts
  2. Konaté, Mariam M; Krushkal, Julia; Li, Ming-Chung; Chen, Li; Kotliarov, Yuri; Palmisano, Alida; Pauly,Rini; Xie, Qian; Williams, P Mickey; McShane, Lisa M; Zhao, Yingdong
  3. Journal of Translational Medicine. 2024, Aug 05; 22(1): 733.
  1. 6.   Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
  2. Thomas, Joanna R; Frye, William J E; Robey, Robert W; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Morgan,Tamara; Edmondson,Elijah; Salazar, Paula B; Ambudkar, Suresh V; Gottesman, Michael M
  3. Fluids and Barriers of the CNS. 2024, Mar 15; 21(1): 27.
  1. 7.   N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants
  2. Mahajan,Pankaj; Smith,Steven; Li, Min; Craigie, Robert; Hughes,Stephen; Zhao,Xuezhi; Burke,Terrence
  3. ACS Infectious Diseases. 2024, Feb 12;
  1. 8.   PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
  2. Torres-Ayuso, Pedro; Katerji,Meghri; Mehlich, Dawid; Lookingbill, Sophia A; Sabbasani, Venkata R; Liou, Hope; Casillas, Andrea L; Chauhan, Shailender S; Serwa, Remigiusz; Rubin,Maxine; Marusiak, Anna A; Swenson, Rolf E; Warfel, Noel A; Brognard,John
  3. Cell Chemical Biology. 2023, Nov 16;
  1. 9.   Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum
  2. Bennett, John M; Ward, Kurt E; Muir, Ryan K; Kabeche, Stephanie; Yoo,Euna; Yeo, Tomas; Lam, Grace; Zhang, Hao; Almaliti, Jehad; Berger, Gabriel; Faucher, Franco F; Lin, Gang; Gerwick, William H; Yeh, Ellen; Fidock, David A; Bogyo, Matthew
  3. ACS Infectious Diseases. 2023, Oct 13; 9(10): 2036-2047.
  1. 10.   D-Allulose Ameliorates Dysregulated Macrophage Function and Mitochondrial NADH Homeostasis, Mitigating Obesity-Induced Insulin Resistance
  2. Bae, Heekyong R; Shin, Su-Kyung; Han, Youngji; Yoo, Ji-Hyeon; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. Nutrients. 2023, Sep 29; 15(19):
  1. 11.   Rilotumumab Resistance Acquired by Intracrine Hepatocyte Growth Factor Signaling
  2. Cecchi, Fabiola; Rex, Karen; Schmidt, Joanna; Vocke, Cathy D; Lee, Young H; Burkett, Sandra; Baker, Daniel; Damore, Michael A; Coxon, Angela; Burgess, Teresa L; Bottaro, Donald P
  3. Cancers. 2023, Jan 11; 15(2):
  1. 12.   Insights into HIV-1 Transmission Dynamics Using Routinely Collected Data in the Mid-Atlantic United States
  2. Kassaye, Seble G; Grossman, Zehava; Vengurlekar, Priyanka; Chai, William; Wallace, Megan; Rhee, Soo-Yon; Meyer, William A; Kaufman, Harvey W; Castel, Amanda; Jordan, Jeanne; Crandall, Keith A; Kang, Alisa; Kumar, Princy; Katzenstein, David A; Shafer, Robert W; Maldarelli,Frank
  3. Viruses. 2022, Dec 25; 15(1):
  1. 13.   Cefiderocol and the Need for Higher-Quality Evidence: Methods Matter for Patients
  2. Epling, Brian P; Powers,John
  3. Antimicrobial Agents and Chemotherapy. 2022, Jul 18; e0076622.
  1. 14.   CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling
  2. Chen,Zibo; Yuan, Tao; Yan, Fangjie; Ye, Song; Xie, Qin; Zhang, Bo; Lin, Nengmin; He, Qiaojun; Yang, Bo; Zhu, Hong
  3. BMC Cancer. 2022, Apr 19; 22(1): 425.
  1. 15.   Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate
  2. Funasaki, Shintaro; Mehanna, Sally; Ma, Wenjuan; Nishizawa, Hidekazu; Kamikubo, Yasuhiko; Sugiyama, Hiroshi; Ikeda, Shuji; Motoshima, Takanobu; Hasumi, Hisashi; Linehan, W Marston; Schmidt,Laura; Ricketts, Chris; Suda, Toshio; Oike, Yuichi; Kamba, Tomomi; Baba, Masaya
  3. Cancer Science. 2022, Apr 09;
  1. 16.   Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
  2. Robey, Robert W.; Robinson, Andrea N.; Ali-Rahmani, Fatima; Huff, Lyn M.; Lusvarghi, Sabrina; Vahedi, Shahrooz; Hotz, Jordan M.; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Edmondson,Elijah; Lee, Tobie D.; Roth, Jacob S.; Lee, Olivia W.; Shen, Min; Tanner, Kandice; Hall, Matthew D.; Ambudkar, Suresh; Gottesman, Michael M.
  3. SCIENTIFIC REPORTS. 2021, Dec 17; 11(1):
  1. 17.   INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
  2. Smith, Steven J; Ferris,Andrea; Zhao, Xuezhi; Pauly,Gary; Schneider,Joel; Burke,Terrence; Hughes,Stephen
  3. Viruses. 2021, Dec 14; 13(12):
  1. 18.   Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target
  2. Adams, Oliver; Deme,Justin; Parker, Joanne L; Fowler, Philip W; Lea,Susan; Newstead, Simon
  3. Structure (London, England : 1993). 2021, Oct 7; 29(10): 1182-1191.
  1. 19.   Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model
  2. El Meskini,Rajaa; Atkinson,Devon; Kulaga, Alan; Abdelmaksoud,Abdalla; Gumprecht, Michelle; Pate, Nathan; Hayes, Susana; Oberst, Michael; Kaplan, Ian M.; Raber, Patrick; Van Dyke, Terry; Sharan,Shyam; Hollingsworth, Robert; Day, Chi-Ping; Merlino, Glenn; Ohler,Zoe
  3. Molecular cancer research : MCR. 2021, Aug 1; 19(8): 1422-1436.
  1. 20.   Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s
  2. Hou, Shurong; Lee, Jeong Min; Myint,Wazo; Matsuo,Hiroshi; Yilmaz, Nese Kurt; Schiffer, Celia A.
  3. Journal of Biological Chemistry. 2021, Aug; 297(2):
  1. 21.   Drugging multiple same-allele driver mutations in cancer
  2. Nussinov,Ruth; Zhang,Mingzhen; Maloney,Ryan; Jang, Hyunbum
  3. Expert Opinion on Drug Discovery. 2021, Aug; 16(8): 823-828.
  1. 22.   The dystonia gene THAP1 controls DNA double-strand break repair choice
  2. Shinoda, Kenta; Zong, Dali; Callen, Elsa; Wu, Wei; Dumitrache, Lavinia C.; Belinky, Frida; Chari,Raj; Wong, Nancy; Ishikawa, Momoko; Stanlie, Andre; Multhaupt-Buell, Trisha; Sharma, Nutan; Ozelius, Laurie; Ehrlich, Michelle; McKinnon, Peter J.; Nussenzweig, Andre
  3. MOLECULAR CELL. 2021, Jun 17; 81(12): 2611-2624.e10.
  1. 23.   SMAC Mimetic/IAP Inhibitor Birinapant Enhances Radiosensitivity of Glioblastoma Multiforme
  2. Cerna, David; Lim, Bora; Adelabu, Yusuf; Yoo, Stephen; Carter, Donna; Fahim, Ahmed; Mitsuuchi, Yasuhiro; Teicher, Beverly A.; Bernhard, Eric; Coleman, C. Norman; Takebe, Naoko; Ahmed, Mansoor M.
  3. Radiation Research. 2021, Jun; 195(6): 549-560.
  1. 24.   Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action
  2. Covell,David
  3. PloS one. 2021, Apr 28; 16(4):
  1. 25.   Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs
  2. Smith, Steven J.; Zhao,Xue Zhi; Passos, Dario Oliveira; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. Viruses (Basel). 2021, Jan 29; 13(2):
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