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  1. 1.   Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)
  2. Hare, S.; Smith, S. J.; Metifiot, M.; Jaxa-Chamiec, A.; Pommier, Y.; Hughes, S. H.; Cherepanov, P.
  3. Molecular Pharmacology. 2011, Oct; 80(4): 565-572.
  1. 2.   Mechanisms and Factors that Influence High Frequency Retroviral Recombination
  2. Delviks-Frankenberry, K.; Galli, A.; Nikolaitchik, O.; Mens, H.; Pathak, V. K.; Hu, W. S.
  3. Viruses-Basel. 2011, Sep; 3(9): 1650-1680.
  1. 3.   Phenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations
  2. Lengruber, R. B.; Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Baumann, J.; Santos, A. F.; Pathak, V. K.; Soares, M. A.
  3. Journal of Antimicrobial Chemotherapy. 2011, Apr; 66(4): 702-708.
  1. 4.   Comparison of standard PCR/cloning to single genome sequencing for analysis of HIV-1 populations
  2. Jordan, M. R.; Kearney, M.; Palmer, S.; Shao, W.; Maldarelli, F.; Coakley, E. P.; Chappey, C.; Wanke, C.; Coffin, J. M.
  3. Journal of Virological Methods. 2010, Sep; 168(1-2): 114-120.
  1. 5.   Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants during Replication
  2. Galli, A.; Kearney, M.; Nikolaitchik, O. A.; Yu, S.; Chin, M. P. S.; Maldarelli, F.; Coffin, J. M.; Pathak, V. K.; Hu, W. S.
  3. Journal of Virology. 2010, Aug; 84(15): 7651-7661.
  1. 6.   Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2009 930(1-3): 157-161.
  1. 7.   In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT
  2. Boyer, P. L.; Stenbak, C. R.; Hoberman, D.; Linial, M. L.; Hughes, S. H.
  3. Virology. 2007, Oct; 367(2): 253-264.
  1. 8.   Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097
  2. Das, K.; Sarafianos, S. G.; Clark, A. D.; Boyer, P. L.; Hughes, S. H.; Arnold, E.
  3. Journal of Molecular Biology. 2007, Jan; 365(1): 77-89.
  1. 9.   Crystallography and the design of anti-AIDS drugs: Conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
  2. Das, K.; Lewi, P. J.; Hughes, S. H.; Arnold, E.
  3. Progress in Biophysics and Molecular Biology. 2005, JUN; 88(2): 209-231.
  1. 10.   Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations
  2. Johnston, E.; Dupnik, K. M.; Gonzales, M. J.; Winters, M. A.; Rhee, S. Y.; Imamichi, T.; Shafer, R. W.
  3. Aids. 2005, APR 29; 19(7): 731-733.
  1. 11.   In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques
  2. Ambrose, Z.; Boltz, V.; Palmer, S.; Coffin, J. M.; Hughes, S. H.; KewalRamani, V. N.
  3. Journal of Virology. 2004, DEC; 78(24): 13553-13561.
  1. 12.   Effects of the Delta 67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision
  2. Boyer, P. L.; Imamichi, T.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, SEP; 78(18): 9987-9997.
  1. 13.   Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions
  2. Svarovskaia, E. S.; Barr, R.; Zhang, X. C.; Pais, G. C. G.; March, C.; Pommier, Y.; Burke, T. R.; Pathak, V. K.
  3. Journal of Virology. 2004 78(7): 3210-3222.
  1. 14.   The M184V mutation reduces the selective excision of zidovudine 5 '-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1
  2. Boyer, P. L.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2002 76(7): 3248-3256.
  1. 15.   Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 angstrom resolution
  2. Ding, J. P.; Das, K.; Hsiou, Y.; Sarafianos, S. G.; Clark, A. D.; Jacobo-Molina, A.; Tantillo, C.; Hughes, S. H.; Arnold, E.
  3. Journal of Molecular Biology. 1998 284(4): 1095-1111.
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