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  1. 2.   Natural Occurring Polymorphisms in HIV-1 Integrase and RNase H Regulate Viral Release and Autoprocessing
  2. Imamichi, Tomozumi; Bernbaum, John G.; Laverdure, Sylvain; Yang, Jun; Chen, Qian; Highbarger, Helene; Hao, Ming; Sui, Hongyan; Dewar, Robin; Chang, Weizhong; Lane, H. Clifford
  3. Journal of Virology . 2021, Dec; 95(23):
  1. 3.   Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
  2. Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler,John; Wilson,Jennifer; Corona, Angela; Le Grice,Stuart; Tramontano, Enzo
  3. Journal of enzyme inhibition and medicinal chemistry. 2020, Dec; 35(1): 1953-1963.
  1. 4.   Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase
  2. Boyer, Paul; Smith, Steven; Zhao, Xue Zhi; Das, Kalyan; Gruber, Kevin; Arnold, Eddy; Burke, Terrence; Hughes, Stephen
  3. Journal of Virology. 2018, Jul; 92(13): e02203-17.
  1. 5.   Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3
  2. Rausch, Jason; Miller, Jennifer; Legrice, Stuart
  3. VIRUSES-BASEL. 2017, Mar; 9(3):
  1. 6.   Preparation of a Conditional RNA Switch.
  2. Zakrevsky, Paul; Parlea, Lorena; Viard, Mathias; Bindewald, Eckart; Afonin, Kirill A; Shapiro, Bruce
  3. Methods in molecular biology (Clifton, N.J.). 2017 1632: 303-324.
  1. 7.   Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus
  2. Zhou, D. W.; Chung, S. H.; Miller, M.; Le Grice, S. F. J.; Wlodawer, A.
  3. Journal of Structural Biology. 2012, Mar; 177(3): 638-645.
  1. 8.   An evaluation of the RNase H inhibitory effects of Vietnamese medicinal plant extracts and natural compounds
  2. Tai, B. H.; Nhut, N. D.; Nhiem, N. X.; Quang, T. H.; Nguyen, T. T. N.; Bui, T. T. L.; Huong, T. T.; Wilson, J.; Beutler, J. A.; Ban, N. K.; Cuong, N. M.; Kim, Y. H.
  3. Pharmaceutical Biology. 2011, Oct; 49(10): 1046-1051.
  1. 9.   The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC
  2. Davis, C. A.; Parniak, M. A.; Hughes, S. H.
  3. Virology. 2011, Oct; 419(2): 64-71.
  1. 10.   Mechanisms of HIV-1 drug resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors
  2. Nikolenko, G. N.; Kotelkin, A. T.; Oreshkova, S. F.; Ilyichev, A. A.
  3. Molecular Biology. 2011, Feb; 45(1): 93-109.
  1. 11.   The "Connection" Between HIV Drug Resistance and RNase H
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Pathak, V. K.
  3. Viruses-Basel. 2010, Jul; 2(7): 1476-1503.
  1. 12.   HIV-1 Reverse Transcriptase Can Simultaneously Engage Its DNA/RNA Substrate at Both DNA Polymerase and RNase H Active Sites: Implications for RNase H Inhibition
  2. Beilhartz, G. L.; Wendeler, M.; Baichoo, N.; Rausch, J.; Le Grice, S.; Gotte, M.
  3. Journal of Molecular Biology. 2009 388(3): 462-474.
  1. 13.   HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Boyer, P. L.; Hughes, S. H.; Coffin, J. M.; Jere, A.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(31): 10943-10948.
  1. 14.   Mutations in the connection domain of HIV-1 reverse transcriptase increase 3 '-azido-3 '-deoxythymidine resistance
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Fivash, M. J.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Jan; 104(1): 317-322.
  1. 15.   Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization
  2. McWilliams, M. J.; Julias, J. G.; Sarafianos, S. G.; Alvord, W. G.; Arnold, E.; Hughes, S. H.
  3. Virology. 2006, May; 348(2): 378-388.
  1. 16.   Synthesis, processing, and composition of the virion-associated HTLV-1 reverse transcriptase
  2. Mitchell, M. S.; Tozser, J.; Princler, G.; Lloyd, P. A.; Auth, A.; Derse, D.
  3. Journal of Biological Chemistry. 2006, FEB 17; 281(7): 3964-3971.
  1. 17.   Examining Ty3 polypurine tract structure and function by nucleoside analog interference
  2. Dash, C.; Marino, J. P.; Le Grice, S. F. J.
  3. Journal of Biological Chemistry. 2006, FEB 3; 281(5): 2773-2783.
  1. 19.   Alternate polypurine tracts (PPTs) affect the Rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction
  2. Chang, K. W.; Julias, J. G.; Alvord, W. G.; Oh, J.; Hughes, S. H.
  3. Journal of Virology. 2005, NOV; 79(21): 13694-13704.
  1. 20.   Preliminary physical mapping of RNA-RNA linkages in the genomic RNA of Moloney murine leukemia virus
  2. Hibbert, C. S.; Rein, A.
  3. Journal of Virology. 2005, JUL; 79(13): 8142-8148.
  1. 21.   Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 8; 102(6): 2093-2098.
  1. 22.   Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones
  2. Budihas, S. R.; Gorshkova, I.; Gaidamakov, S.; Wamiru, A.; Bona, M. K.; Parniak, M. A.; Crouch, R. J.; McMahon, J. B.; Beutler, J. A.; Le Grice, S. F. J.
  3. Nucleic Acids Research. 2005 33(4): 1249-1256.
  1. 23.   Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer
  2. Mbisa, J. L.; Nikolenko, G. N.; Pathak, V. K.
  3. Journal of Virology. 2005, JAN; 79(1): 419-427.
  1. 24.   Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase
  2. Bibillo, A.; Lener, D.; Klarmann, G. J.; Le Grice, S. F. J.
  3. Nucleic Acids Research. 2005 33(1): 171-181.
  1. 25.   RNase H domains obtained from treatment-experienced patients increase resistance to AZT
  2. Nikolenko, G. N.; Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Antiviral Therapy. 2005 10(4): S89-S89.
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