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  1. 1.   Scaffolding viral protein NC nucleates phase separation of the HIV-1 biomolecular condensate
  2. Monette, Anne; Niu, Meijuan; Nijhoff Asser, Maya; Gorelick,Robert; Mouland, Andrew J
  3. Cell Reports. 2022, Aug 23; 40(8): 111251.
  1. 2.   Relative domain orientation of the L289K HIV-1 reverse transcriptase monomer
  2. Xi, Zhaoyong; Ilina, Tatiana V; Guerrero, Michel; Fan,Lixin; Sluis-Cremer, Nicolas; Wang,Yun-Xing; Ishima, Rieko
  3. Protein Science : a publication of the Protein Society. 2022, May; 31(5): e4307.
  1. 3.   Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)
  2. Harrison, Jerry Joe E K; Tuske, Steve; Das, Kalyan; Ruiz, Francesc X; Bauman, Joseph D; Boyer,Paul; DeStefano, Jeffrey J; Hughes,Stephen; Arnold, Eddy
  3. Viruses. 2021, Aug; 13(8):
  1. 4.   In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns
  2. Lin, Shu-Hong; Wang, Youjin; Hartley, Stephen W.; Karyadi, Danielle M.; Lee, Olivia W.; Zhu, Bin; Zhou,Weiyin; Brown, Derek W.; Beilstein-Wedel, Erin; Hazra, Rohan; Kacanek, Deborah; Chadwick, Ellen G.; Marsit, Carmen J.; Poirier, Miriam C.; Brummel, Sean S.; Chanock, Stephen J.; Engels, Eric A.; Machiela, Mitchell J.
  3. AIDS. 2021, Aug 1; 35(10): 1525-1535.
  1. 5.   Structure-Based Non-Nucleoside Inhibitor Design: Developing Inhibitors that Are Effective Against Resistant Mutants
  2. Smith,Steven; Pauly,Gary; Hewlett, Katharine; Schneider,Joel; Hughes,Stephen
  3. Chemical biology & drug design. 2020, SEP 17;
  1. 6.   (Q)SAR Models of HIV-1 Protein Inhibition by Drug-Like Compounds
  2. Stolbov, Leonid A; Druzhilovskiy, Dmitry S; Filimonov, Dmitry A; Nicklaus,Marc; Poroikov, Vladimir V
  3. Molecules (Basel, Switzerland). 2020, Jan 1; 25(1):
  1. 7.   Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3
  2. Rausch, Jason; Miller, Jennifer; Legrice, Stuart
  3. VIRUSES-BASEL. 2017, Mar; 9(3):
  1. 8.   A Triazinone Derivative Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity
  2. Urano, E.; Miyauchi, K.; Kojima, Y.; Hamatake, M.; Ablan, S. D.; Fudo, S.; Freed, E. O.; Hoshino, T.; Komano, J.
  3. Chemmedchem. 2016, 19-Oct; 11(20): 2320-2326.
  1. 9.   The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC
  2. Davis, C. A.; Parniak, M. A.; Hughes, S. H.
  3. Virology. 2011, Oct; 419(2): 64-71.
  1. 10.   Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine
  2. Boltz, V. F.; Zheng, Y.; Lockman, S.; Hong, F. Y.; Halvas, E. K.; McIntyre, J.; Currier, J. S.; Chibowa, M. C.; Kanyama, C.; Nair, A.; Owino-Ong'or, W.; Hughes, M.; Coffin, J. M.; Mellors, J. W.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, May; 108(22): 9202-9207.
  1. 11.   Mechanisms of HIV-1 drug resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors
  2. Nikolenko, G. N.; Kotelkin, A. T.; Oreshkova, S. F.; Ilyichev, A. A.
  3. Molecular Biology. 2011, Feb; 45(1): 93-109.
  1. 12.   Reverse transcriptase in motion: Conformational dynamics of enzyme-substrate interactions
  2. Gotte, M.; Rausch, J. W.; March, B.; Sarafianos, S.; Le Grice, S. F. J.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2010, May; 1804(5): 1202-1212.
  1. 13.   Structural studies of series HIV-1 nonnucleoside reverse transcriptase inhibitors 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazoles with different 4-substituents
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2010, Mar; 966(1-3): 53-58.
  1. 14.   Structure of HIV-1 nonnucleoside reverse transcriptase inhibitors derivatives of N-benzyl-benzimidazole with different substituents in position 4
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2010, Jan; 963(2-3): 188-193.
  1. 15.   HIV-1 Reverse Transcriptase Can Simultaneously Engage Its DNA/RNA Substrate at Both DNA Polymerase and RNase H Active Sites: Implications for RNase H Inhibition
  2. Beilhartz, G. L.; Wendeler, M.; Baichoo, N.; Rausch, J.; Le Grice, S.; Gotte, M.
  3. Journal of Molecular Biology. 2009 388(3): 462-474.
  1. 16.   Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2009 930(1-3): 157-161.
  1. 17.   Structural investigation of HIV-1 nonnucleoside reverse transcriptase inhibitors: 2-Aryl-substituted benzimidazoles
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2009 937(1-3): 34-38.
  1. 18.   Synthesis of conformationally locked carbocyclic nucleoside phosphonates to probe the active site of HIV-1 RT
  2. Saneyoshi, H.; Vu, B. C.; Hughes, S. H.; Boyer, P. L.; Sarafianos, S. G.; Marquez, V. E.
  3. Nucleic acids symposium series (2004). 2008 (52): 623-4.
  1. 19.   Targeting to the endoplasmic reticulum improves the folding of recombinant human telomerase reverse transcriptase
  2. Wu, C. K.; Gousset, K.; Hughes, S. H.
  3. Protein Expression and Purification. 2007, Nov; 56(1): 8-19.
  1. 20.   In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT
  2. Boyer, P. L.; Stenbak, C. R.; Hoberman, D.; Linial, M. L.; Hughes, S. H.
  3. Virology. 2007, Oct; 367(2): 253-264.
  1. 21.   HIV-1 protease dimer interface mutations that compensate for viral reverse transcriptase instability in infectious virions
  2. Olivares, I.; Mulky, A.; Boross, P. I.; Tozser, J.; Kappes, J. C.; Lopez-Galindez, C.; Menendez-Arias, L.
  3. Journal of Molecular Biology. 2007, Sep; 372(2): 369-381.
  1. 22.   The nucleoside analogs 4 ' C-Methyl thymidine and 4 ' C-Ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants
  2. Boyer, P. L.; Julias, J. G.; Ambrose, Z.; Siddiqui, M. A.; MarqueZ, V. E.; Hughes, S. H.
  3. Journal of Molecular Biology. 2007, Aug; 371(4): 873-882.
  1. 23.   Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT
  2. Nissley, D. V.; Radzio, J.; Ambrose, Z.; Sheen, C. W.; Hamamouch, N.; Moore, K. L.; Tachedjian, G.; Sluis-Cremer, N.
  3. Biochemical Journal. 2007, May; 404: 151-157.
  1. 24.   A second-site suppressor significantly improves the defective phenotype impolsed by mutation of an aromatic residue in the N-terminal domain of the HIV-1 capsid protein
  2. Tang, S. X.; Ablan, S.; Dueck, M.; Ayala-Lopez, W.; Soto, B.; Caplan, M.; Nagashima, K.; Hewlett, I. K.; Freed, E. O.; Levin, J. G.
  3. Virology. 2007, Mar; 359(1): 105-115.
  1. 25.   Analysis of amino acids in the beta 7-beta 8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication
  2. Mulky, A.; Vu, B. C.; Conway, J. A.; Hughes, S. H.; Kappes, J. C.
  3. Journal of Molecular Biology. 2007, Feb; 365(5): 1368-1378.
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