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  1. 1.   Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors [1]
  2. Andreani, A.; Granaiola, M.; Leoni, A.; Locatelli, A.; Morigi, R.; Rambaldi, M.; Varoli, L.; Lannigan, D.; Smith, J.; Scudiero, D.; Kondapaka, S.; Shoemaker, R. H.
  3. European Journal of Medicinal Chemistry. 2011, Sep; 46(9): 4311-4323.
  1. 2.   Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation human myeloid leukemia cells
  2. Ozpolat, B.; Akar, U.; Steiner, M.; Zorrilia-Calancha, I.; Tirado-Gomez, M.; Colburn, N.; Danilenko, M.; Kornblau, S.; Berestein, G. L.
  3. Molecular Cancer Research. 2007, Jan; 5(1): 95-108.
  1. 3.   Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore
  2. Nguyen, T. L.; Gussio, R.; Smith, J. A.; Lannigan, D. A.; Hecht, S. M.; Scudiero, D. A.; Shoemaker, R. H.; Zaharevitz, D. W.
  3. Bioorganic & Medicinal Chemistry. 2006, Sep; 14(17): 6097-6105.
  1. 4.   Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappa B activation and transformation in resistant JB6 cells
  2. Hu, J.; Nakano, H.; Sakurai, H.; Colburn, N. H.
  3. Carcinogenesis. 2004, OCT; 25(10): 1991-2003.
  1. 5.   Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins - A molecular link of two tumor suppressor pathways
  2. Birchenall-Roberts, M. C.; Fu, T.; Bang, O. S.; Dambach, M.; Resau, J. H.; Sadowski, C. L.; Bertolette, D. C.; Lee, H. J.; Kim, S. J.; Ruscetti, F. W.
  3. Journal of Biological Chemistry. 2004 279(24): 25605-25613.
  1. 6.   Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells
  2. Cao, Z. H.; Flanders, K. C.; Bertolette, D.; Lyakh, L. A.; Wurthner, J. U.; Parks, W. T.; Letterio, J. J.; Ruscetti, F. W.; Roberts, A. B.
  3. Blood. 2003 101(2): 498-507.
  1. 7.   Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition
  2. Dudkin, L.; Dilling, M. B.; Cheshire, P. J.; Harwood, F. C.; Hollingshead, M.; Arbuck, S. G.; Travis, R.; Sausville, E. A.; Houghton, P. J.
  3. Clinical Cancer Research. 2001 7(6): 1758-1764.
  1. 8.   Role of NF-kappa B in p53-mediated programmed cell death
  2. Ryan, K. M.; Ernst, M. K.; Rice, N. R.; Vousden, K. H.
  3. Nature. 2000 404(6780): 892-897.
  1. 9.   Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation
  2. Watts, R. G.; Huang, C. S.; Young, M. R.; Li, J. J.; Dong, Z. G.; Pennie, W. D.; Colburn, N. H.
  3. Oncogene. 1998 17(26): 3493-3498.
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