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  1. 1.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 2.   Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma
  2. Kowalczyk, Joshua T.; Wan, Xiaolin; Hernandez, Edjay R.; Luo, Ruibai; Lyons, Gaelyn C.; Wilson, Kelli M.; Gallardo, Devorah C.; Isanogle,Kristine; Robinson,Christina; Mendoza, Arnulfo; Heske, Christine M.; Chen, Jinqui-Qiu; Luo, Xiaoling; Kelly, Alexander E.; Difilippantonio,Simone; Robey, Robert W.; Thomas, Craig J.; Sackett, Dan L.; Morrison,Deborah; Randazzo, Paul A.; Jenkins, Lisa M. Miller; Yohe, Marielle E.
  3. MOLECULAR CANCER THERAPEUTICS. 2021, Feb 1; 20(2): 307-319.
  1. 3.   Threonine Tyrosine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy
  2. Zheng, Lin; Chen, Zibo; Kawakami, Masanori; Chen, Yulong; Roszik, Jason; Mustachio, Lisa Maria; Kurie, Jonathan M; Villalobos, Pamela; Lu, Wei; Behren, Carmen; Mino, Barbara; Solis, Luisa M; Silvester, Jennifer; Thu, Kelsie L; Cescon, David W; Rodriguez-Canales, Jaime; Wistuba, Ignacio I; Mak, Tak W; Liu, Xi; Dmitrovsky,Ethan
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1775-1786.
  1. 4.   A New View of Pathway-Driven Drug Resistance in Tumor Proliferation
  2. Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum
  3. TRENDS IN PHARMACOLOGICAL SCIENCES. 2017, May; 38(5): 427-437.
  1. 5.   A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
  2. Ulmer, Baerbel; Tingler, Melanie; Kurz, Sabrina; Maerker, Markus; Andre, Philipp; Moench, Dina; Campione, Marina; Deissler, Kirsten; Lewandoski, Mark; Thumberger, Thomas; Schweickert, Axel; Fainsod, Abraham; Steinbeisser, Herbert; Blum, Martin
  3. SCIENTIFIC REPORTS. 2017, 2017-02-21; 7
  1. 6.   Genetic deletion of trkB.T1 increases neuromuscular function
  2. Dorsey, S. G.; Lovering, R. M.; Renn, C. L.; Leitch, C. C.; Liu, X. Y.; Tallon, L. J.; Sadzewicz, L. D.; Pratap, A.; Ott, S.; Sengamalay, N.; Jones, K. M.; Barrick, C.; Fulgenzi, G.; Becker, J.; Voelker, K.; Talmadge, R.; Harvey, B. K.; Wyatt, R. M.; Vernon-Pitts, E.; Zhang, C.; Shokat, K.; Fraser-Liggett, C.; Balice-Gordon, R. J.; Tessarollo, L.; Ward, C. W.
  3. American Journal of Physiology-Cell Physiology. 2012, Jan; 302(1): C141-C153.
  1. 7.   The Role of Response Elements Organization in Transcription Factor Selectivity: The IFN-beta Enhanceosome Example
  2. Pan, Y. P.; Nussinov, R.
  3. Plos Computational Biology. 2011, Jun; 7(6): 14.
  1. 8.   LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes?
  2. Orr, S. J.; McVicar, D. W.
  3. Journal of Leukocyte Biology. 2011, Jan; 89(1): 11-19.
  1. 9.   AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
  2. Smith, F. D.; Langeberg, L. K.; Cellurale, C.; Pawson, T.; Morrison, D. K.; Davis, R. J.; Scott, J. D.
  3. Nature Cell Biology. 2010, Dec; 12(12): 1242-U287.
  1. 10.   Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 alpha Expression in an AhR-Independent Fashion
  2. Terzuoli, E.; Puppo, M.; Rapisarda, A.; Uranchimeg, B.; Cao, L. A.; Burger, A. M.; Ziche, M.; Melillo, G.
  3. Cancer Research. 2010, Sep 1; 70(17): 6837-6848.
  1. 11.   Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands
  2. Mureith, M. W.; Chang, J. J.; Lifson, J. D.; Ndung'u, T.; Altfeld, M.
  3. Aids. 2010, Jul; 24(12): 1841-1848.
  1. 12.   Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice
  2. Panguluri, S. K.; Bhatnagar, S.; Kumar, A.; McCarthy, J. J.; Srivastava, A. K.; Cooper, N. G.; Lundy, R. F.
  3. Plos One. 2010, Jan 19; 5(1): 17.
  1. 13.   Interleukin-15 Enhances Proteasomal Degradation of Bid in Normal Lymphocytes: Implications for Large Granular Lymphocyte Leukemias
  2. Hodge, D. L.; Yang, J.; Buschman, M. D.; Schaughency, P. M.; Dang, H.; Bere, W.; Yang, Y. L.; Savan, R.; Subleski, J. J.; Yin, X. M.; Loughran, T. P.; Young, H. A.
  3. Cancer Research. 2009 69(9): 3986-3994.
  1. 14.   Reduced Expression of CD45 Protein-tyrosine Phosphatase Provides Protection against Anthrax Pathogenesis
  2. Panchal, R. G.; Ulrich, R. L.; Bradfute, S. B.; Lane, D.; Ruthel, G.; Kenny, T. A.; Iversen, P. L.; Anderson, A. O.; Gussio, R.; Raschke, W. C.; Bavari, S.
  3. Journal of Biological Chemistry. 2009 284(19): 12874-12885.
  1. 15.   p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
  2. Satyanarayana, A.; Hilton, M. B.; Kaldis, P.
  3. Molecular Biology of the Cell. 2008 19(1): 65-77.
  1. 16.   Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody
  2. Shanker, A.; Brooks, A. D.; Tristan, C. A.; Wine, J. W.; Elliott, P. J.; Yagita, H.; Takeda, K.; Smyth, M. J.; Murphy, W. J.; Sayers, T. J.
  3. Journal of the National Cancer Institute. 2008 100(9): 649-662.
  1. 17.   The wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by P13K-like kinases
  2. Yamaguchi, H.; Durell, S. R.; Chatterjee, D. K.; Anderson, C. W.; Appella, E.
  3. Biochemistry. 2007, Nov; 46(44): 12594-12603.
  1. 18.   The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells
  2. Mi, L. X.; Wang, X. T.; Govind, S.; Hood, B. L.; Veenstra, T. D.; Conrads, T. P.; Saha, D. T.; Goldman, R.; Chung, F. L.
  3. Cancer Research. 2007, Jul; 67(13): 6409-6416.
  1. 19.   Grb10 and active Raf-1 kinase promote bad-dependent cell survival
  2. Kebache, S.; Ash, J.; Annis, M. G.; Hagan, J.; Huber, M.; Hassard, J.; Stewart, C. L.; Whiteway, M.; Nantel, A.
  3. Journal of Biological Chemistry. 2007, Jul; 282(30): 21873-21883.
  1. 20.   Transactivation of the epidermal growth factor receptor by formylpeptide receptor exacerbates the malignant behavior of human glioblastoma cells
  2. Huang, J.; Hu, J. Y.; Bian, X. W.; Chen, K. Q.; Gong, W. H.; Dunlop, N. M.; Howard, O. M. Z.; Wang, J. M.
  3. Cancer Research. 2007, Jun; 67(12): 5906-5913.
  1. 21.   Integrated molecular profiling of SOD2 expression in multiple myeloma
  2. Hurt, E. M.; Thomas, S. B.; Peng, B. J.; Farrar, W. L.
  3. Blood. 2007, May; 109(9): 3953-3962.
  1. 22.   Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1
  2. Lovvorn, H. N.; Boyle, S.; Shi, G.; Shyr, Y.; Wills, M. L.; Perantoni, A. O.; de Caestecker, M.
  3. Journal of Pediatric Surgery. 2007, Mar; 42(3): 474-481.
  1. 23.   Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages
  2. Kim, S. H.; Lee, S.; Suk, K.; Bark, H.; Jun, C. D.; Kim, D. K.; Choi, C. H.; Yoshimura, T.
  3. Free Radical Biology and Medicine. 2007, Feb; 42(3): 343-352.
  1. 24.   Itch genetically interacts with Notch1 in a mouse autoimmune disease model
  2. Matesic, L. E.; Haines, D. C.; Copeland, N. G.; Jenkins, N. A.
  3. Human Molecular Genetics. 2006, Dec; 15(24): 3485-3497.
  1. 25.   PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes
  2. Robinson-White, A. J.; Leitner, W. W.; Aleem, E.; Kaldis, P.; Bossis, I.; Stratakis, C. A.
  3. Cancer Research. 2006, Nov; 66(21): 10603-10612.
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