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  1. 1.   Adoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen spreading and elimination of antigen-negative tumor variants
  2. Zhang, Ling; Norberg, Scott M; Karimipour, Farrah; Davies, John S; Kuznetsov, Alex; Lassoued, Wiem; Burnett, Daniel; Homan,Philip; Cam, Margaret; Sinkoe, Andrew; Xue, Ping; Gulley, James L; Hinrichs, Christian S
  3. Journal for Immunotherapy of Cancer. 2024, Nov 18; 12(11):
  1. 2.   Divergent HLA variations and heterogeneous expression but recurrent HLA loss-of- heterozygosity and common HLA-B and TAP transcriptional silencing across advanced pediatric solid cancers
  2. Lim, Wan Ching; Marques Da Costa, Maria Eugenia; Godefroy, Karine; Jacquet, Eric; Gragert, Loren; Rondof, Windy; Marchais, Antonin; Nhiri, Naima; Dalfovo, Davide; Viard,Mathias; Labaied, Nizar; Khan, Asif M; Dessen, Philippe; Romanel, Alessandro; Pasqualini, Claudia; Schleiermacher, Gudrun; Carrington,Mary; Zitvogel, Laurence; Scoazec, Jean-Yves; Geoerger, Birgit; Salmon, Jerome
  3. Frontiers in Immunology. 2024, Jan 22; 14: 1265469.
  1. 3.   NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer
  2. Salomé, Bérengère; Sfakianos, John P; Ranti, Daniel; Daza, Jorge; Bieber, Christine; Charap, Andrew; Hammer, Christian; Banchereau, Romain; Farkas, Adam M; Ruan, Dan Fu; Izadmehr, Sudeh; Geanon, Daniel; Kelly, Geoffrey; de Real, Ronaldo M; Lee, Brian; Beaumont, Kristin G; Shroff, Sanjana; Wang, Yuanshuo A; Wang, Ying-Chih; Thin, Tin Htwe; Garcia-Barros, Monica; Hegewisch-Solloa, Everardo; Mace, Emily M; Wang, Li; O'Donnell, Timothy; Chowell, Diego; Fernandez-Rodriguez, Ruben; Skobe, Mihaela; Taylor, Nicole; Kim-Schulze, Seunghee; Sebra, Robert P; Palmer, Doug; Clancy-Thompson, Eleanor; Hammond, Scott; Kamphorst, Alice O; Malmberg, Karl-Johan; Marcenaro, Emanuela; Romero, Pedro; Brody, Rachel; Viard,Mathias; Yuki,Yuko; Martin,Pat; Carrington,Mary; Mehrazin, Reza; Wiklund, Peter; Mellman, Ira; Mariathasan, Sanjeev; Zhu, Jun; Galsky, Matthew D; Bhardwaj, Nina; Horowitz, Amir
  3. Cancer Cell. 2022, Sep 12; 40(9): 1027-1043.e9.
  1. 4.   A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer
  2. Manzo, Julia; Puhalla, Shannon; Pahuja, Shalu; Ding, Fei; Lin, Yan; Appleman, Leonard; Tawbi, Hussein; Stoller, Ronald; Lee, James J; Diergaarde, Brenda; Kiesel, Brian F; Yu, Jing; Tan, Antoinette R; Belani, Chandra P; Chew, Helen; Garcia, Agustin A; Morgan, Robert J; Wahner Hendrickson, Andrea E; Visscher, Daniel W; Hurley, Rachel M; Kaufmann, Scott H; Swisher, Elizabeth M; Oesterreich, Steffi; Katz, Tiffany; Ji,Jay; Zhang, Yiping; Parchment, Ralph E; Chen, Alice; Duan, Wenrui; Giranda, Vincent; Shepherd, Stacie P; Ivy, S Percy; Chu, Edward; Beumer, Jan H
  3. Cancer Chemotherapy and Pharmacology. 2022, Apr 18; 89(5): 721-735.
  1. 5.   The mechanism driving a solid-solid phase transition in a biomacromolecular crystal
  2. Ramakrishnan, Saminathan; Stagno,Jason; Heinz,Will; Zuo, Xiaobing; Yu,Ping; Wang,Yun-Xing
  3. IUCrJ. 2021, Jul 01; 8(Pt 4): 655-664.
  1. 6.   Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis
  2. Nguyen, Phuong H.; Ramamoorthy, Ayyalusamy; Sahoo, Bikash R.; Zheng, Jie; Faller, Peter; Straub, John E.; Dominguez, Laura; Shea, Joan-Emma; Dokholyan, Nikolay; De Simone, Alfonso; Ma, Buyong; Nussinov,Ruth; Najafi, Saeed; Ngo, Son Tung; Loquet, Antoine; Chiricotto, Mara; Ganguly, Pritam; McCarty, James; Li, Mai Suan; Hall, Carol; Wang, Yiming; Miller, Yifat; Melchionna, Simone; Habenstein, Birgit; Timr, Stepan; Chen, Jiaxing; Hnath, Brianna; Strodel, Birgit; Kayed, Rakez; Lesne, Sylvain; Wei, Guanghong; Sterpone, Fabio; Doig, Andrew J.; Derreumaux, Philippe
  3. Chemical Reviews. 2021, Feb 24; 121(4): 2545-2647.
  1. 7.   Effect of Capivasertib in Patients With an AKT1 E17K-Mutated Tumor NCI-MATCH Subprotocol EAY131-Y Nonrandomized Trial
  2. Kalinsky, Kevin; Hong, Fangxin; McCourt, Carolyn K.; Sachdev, Jasgit C.; Mitchell, Edith P.; Zwiebel, James A.; Doyle, L. Austin; McShane, Lisa M.; Li, Shuli; Gray, Robert J.; Rubinstein, Larry V.; Patton, David; Williams,Mickey; Hamilton, Stanley R.; Conley, Barbara A.; O'Dwyer, Peter J.; Harris, Lyndsay N.; Arteaga, Carlos L.; Chen, Alice P.; Flaherty, Keith T.
  3. JAMA oncology. 2021, Feb 1; 7(2): 271-278.
  1. 8.   Dabrafenib and Trametinib in Patients With Tumors With BRAFV600E Mutations: Results of the NCI-MATCH Trial Subprotocol H
  2. Salama, April K S; Li, Shuli; Macrae, Erin R; Park, Jong-In; Mitchell, Edith P; Zwiebel, James A; Chen, Helen X; Gray, Robert J; McShane, Lisa M; Rubinstein, Larry V; Patton, David; Williams,Mickey; Hamilton, Stanley R; Armstrong, Deborah K; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay N; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): JCO2000762.
  1. 9.   Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W
  2. Chae, Young K; Hong, Fangxin; Vaklavas, Christos; Cheng, Heather H; Hammerman, Peter; Mitchell, Edith P; Zwiebel, James A; Ivy, S Percy; Gray, Robert J; Li, Shuli; McShane, Lisa M; Rubinstein, Larry V; Patton, David; Williams,Mickey; Hamilton, Stanley R; Mansfield, Aaron; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay N; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, JUL 20; 38(21): 2407-+.
  1. 10.   PI3K inhibitors: review and new strategies
  2. Zhang,Mingzhen; Jang,Hyunbum; Nussinov,Ruth
  3. CHEMICAL SCIENCE. 2020, JUN 21; 11(23): 5855-5865.
  1. 11.   Application of Post Solid-Phase Oxime Ligation to Fine-Tune Peptide-Protein Interactions
  2. Zhao,Xue Zhi; Liu, Fa; Burke,Terrence
  3. Molecules (Basel, Switzerland). 2020, JUN; 25(12):
  1. 12.   LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies
  2. O'Neill,Maura; Chan,King; Jaynes, Jesse M; Knotts, Zachary; Xu,Xia; Abisoye-Ogunniyan, Abisola; Guerin,Theresa; Schlomer,Jerome; Li, Dandan; Cary, Jeffrey W; Rajasekaran, Kanniah; Yates, Clayton; Kozlov,Serguei; Andresson,Thorkell; Rudloff, Udo
  3. Journal of pharmaceutical and biomedical analysis. 2020, Mar 20; 181: 113093.
  1. 13.   Nivolumab Is Effective in Mismatch Repair-Deficient Noncolorectal Cancers: Results From Arm Z1D-A Subprotocol of the NCI-MATCH (EAY131) Study
  2. Azad, Nilofer S; Gray, Robert J; Overman, Michael J; Schoenfeld, Jonathan D; Mitchell, Edith P; Zwiebel, James A; Sharon, Elad; Streicher, Howard; Li, Shuli; McShane, Lisa M; Rubinstein, Larry; Patton, David R; Williams,Mickey; Coffey,Brent; Hamilton, Stanley R; Bahary, Nathan; Suga, J Marie; Hatoum, Hassan; Abrams, Jeffrey S; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, JAN 20; 38(3): 214-+.
  1. 14.   Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies
  2. Puxeddu, Michela; Shen, Hongliang; Bai,Ruoli; Coluccia, Antonio; Nalli, Marianna; Mazzoccoli, Carmela; Da Pozzo, Eleonora; Cavallini, Chiara; Martini, Claudia; Orlando, Viviana; Biagioni, Stefano; Mazzoni, Cristina; Coluccia, Addolorata Maria Luce; Hamel,Ernest; Liu, Te; Silvestri, Romano; La Regina, Giuseppe
  3. European journal of medicinal chemistry. 2020, Jan 1; 185: 111828.
  1. 15.   Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin
  2. Carter, Kevin A.; Luo, Dandan; Geng, Jumin; Stern, Steve; Lovell, Jonathan F.
  3. Molecular cancer therapeutics. 2019, Mar; 18(3): 592-601.
  1. 16.   NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening
  2. Thornburg,Chris; Britt,John; Evans,Jason; Akee,Rhone; Whitt, James A.; Trinh,Spencer; Harris,Matthew; Thompson,Jerell; Ewing,Teresa; Shipley,Suzanne; Grothaus,Paul; Newman,Dave; Schneider,Joel; Grkovic,Tanja; O'Keefe,Barry
  3. ACS CHEMICAL BIOLOGY. 2018, Sep 21; 13(9): 2484-2497.
  1. 17.   Activity-Dependent Neuroplasticity Induced by an Enriched Environment Reverses Cognitive Deficits in Scribble Deficient Mouse
  2. Hilal, Muna L; Moreau, Maité M; Racca, Claudia; Pinheiro, Vera L; Piguel, Nicolas H; Santoni, Marie-Josée; Dos Santos Carvalho, Steve; Blanc, Jean-Michel; Abada, Yah-Se K; Peyroutou, Ronan; Medina, Chantal; Doat, Hélène; Papouin, Thomas; Vuillard, Laurent; Borg, Jean-Paul; Rachel, Rivka; Panatier, Aude; Montcouquiol, Mireille; Oliet, Stéphane H R; Sans, Nathalie
  3. Cerebral cortex (New York, N.Y. : 1991). 2017, Dec; 27(12): 5635-5651.
  1. 18.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 19.   Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin
  2. Day, C. P.; Carter, J.; Bonomi, C.; Hollingshead, M.; Merlino, G.
  3. International Journal of Cancer. 2012, Jan; 130(1): 190-199.
  1. 20.   Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties
  2. Flynn, B. L.; Gill, G. S.; Grobelny, D. W.; Chaplin, J. H.; Paul, D.; Leske, A. F.; Lavranos, T. C.; Chalmers, D. K.; Charman, S. A.; Kostewicz, E.; Shackleford, D. M.; Morizzi, J.; Hamel, E.; Jung, M. K.; Kremmidiotis, G.
  3. Journal of Medicinal Chemistry. 2011, Sep; 54(17): 6014-6027.
  1. 21.   Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside beta-triphosphates
  2. Dash, C.; Ahmadibeni, Y.; Hanley, M. J.; Pandhare, J.; Gotte, M.; Le Grice, S. F. J.; Parang, K.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, Jun; 21(12): 3519-3522.
  1. 22.   A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer
  2. Kelly, R. J.; Draper, D.; Chen, C. C.; Robey, R. W.; Figg, W. D.; Piekarz, R. L.; Chen, X. H.; Gardner, E. R.; Balis, F. M.; Venkatesan, A. M.; Steinberg, S. M.; Fojo, T.; Bates, S. E.
  3. Clinical Cancer Research. 2011, Feb; 17(3): 569-580.
  1. 23.   Development of thyroid gland and ultimobranchial body cyst is independent of p63
  2. Ozaki, T.; Nagashima, K.; Kusakabe, T.; Kakudo, K.; Kimura, S.
  3. Laboratory Investigation. 2011, Jan; 91(1): 138-146.
  1. 24.   Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay
  2. Best, A. M.; Chang, J. J.; Dull, A. B.; Beutler, J. A.; Martinez, E. D.
  3. Journal of Biomedicine and Biotechnology. 2011 11.
  1. 25.   The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy
  2. Xiang, X. R.; Phung, Y.; Feng, M. Q.; Nagashima, K.; Zhang, J. L.; Broaddus, V. C.; Hassan, R.; FitzGerald, D.; Ho, M.
  3. Plos One. 2011, Jan; 6(1): 10.
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