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  1. 1.   Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
  2. Zhu, Jianjian; Patel,Rashmi; Trofka, Anna; Harfe, Brian D; Mackem,Susan
  3. Developmental Cell. 2022, Aug 13; 57(17): 2048-2062.
  1. 2.   John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work?
  2. Zhu, Jianjian; Mackem, Susan
  3. Developmental Biology. 2017, Sep 15; 429(2 Special Issue): 391-400.
  1. 3.   Evolution: Enhanced Footing for Snake Limb Development
  2. Kaltcheva, Maria; Lewandoski, Mark
  3. CURRENT BIOLOGY. 2016, Dec 5; 26(23): R1237-R1240.
  1. 4.   Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway
  2. Zhu, J. J.; Nguyen, M. T.; Nakamura, E.; Yang, J. M.; Mackem, S.
  3. Genesis. 2012, Feb; 50(2): 102-111.
  1. 5.   Analysis of Mutants With Altered Shh Activity and Posterior Digit Loss Supports a Biphasic Model for Shh Function as a Morphogen and Mitogen
  2. Zhu, J. J.; Mackem, S.
  3. Developmental Dynamics. 2011, May; 240(5): 1303-1310.
  1. 6.   Midline signaling regulates kidney positioning but not nephrogenesis through Shh
  2. Tripathi, P.; Guo, Q. S.; Wang, Y. Q.; Coussens, M.; Liapis, H.; Jain, S.; Kuehn, M. R.; Capecchi, M. R.; Chen, F.
  3. Developmental Biology. 2010, Apr; 340(2): 518-527.
  1. 7.   Limb Development Takes a Measured Step Toward Systems Analysis
  2. Mackem, S.; Lewandoski, M.
  3. Science Signaling. 2009, May; 2(71): 4.
  1. 8.   Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling
  2. Suzuki, K.; Yamaguchi, Y.; Villacorte, M.; Mihara, K.; Akiyama, M.; Shimizu, H.; Taketo, M. M.; Nakagata, N.; Tsukiyama, T.; Yamaguchi, T. P.; Birchmeier, W.; Kato, S.; Yamada, G.
  3. Development. 2009 136(3): 367-372.
  1. 9.   LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth
  2. Tzchori, I.; Day, T. F.; Carolan, P. J.; Zhao, Y.; Wassif, C. A.; Li, L.; Lewandoski, M.; Gorivodsky, M.; Love, P. E.; Porter, F. D.; Westphal, H.; Yang, Y.
  3. Development. 2009 136(8): 1375-1385.
  1. 10.   Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic
  2. Xie, Y. X.; Liu, J.; Benbrahim-Tallaa, L.; Ward, J. M.; Logsdon, D.; Diwan, B. A.; Waalkes, M. P.
  3. Toxicology. 2007, Jul; 236(1-2): 7-15.
  1. 11.   Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population
  2. Petersen, D. C.; Glashoff, R. H.; Shrestha, S.; Bergeron, J.; Laten, A.; Gold, B.; van Rensburg, E. J.; Dean, M.; Hayes, V. M.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2005, DEC 15; 40(5): 521-526.
  1. 12.   FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis
  2. Li, C. L.; Xu, X. L.; Nelson, D. K.; Williams, T.; Kuehn, M. R.; Deng, C. X.
  3. Development. 2005, NOV; 132(21): 4755-4764.
  1. 13.   Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning
  2. Verheyden, J. M.; Lewandoski, M.; Deng, C. X.; Harfe, B. D.; Sun, X.
  3. Development. 2005, OCT; 132(19): 4235-4245.
  1. 14.   Frontonasal dysplasia in 3H1 Br/Br mice
  2. McBratney, B. M.; Margaryan, E.; Ma, W. B.; Urban, Z.; Lozanoff, S.
  3. Anatomical Record Part a-Discoveries in Molecular Cellular and Evolutionary Biology. 2003 271A(2): 291-302.
  1. 15.   Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions
  2. Kim, Y. S.; Lewandoski, M.; Perantoni, A. O.; Kurebayashi, S.; Nakanishi, G.; Jetten, A. M.
  3. Journal of Biological Chemistry. 2002 277(34): 30901-30913.
  1. 16.   Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with Transactivation and repressor functions - Roles in kidney development and neurogenesis
  2. Zhang, F.; Nakanishi, G.; Kurebayashi, S.; Yoshino, K.; Perantoni, A.; Kim, Y. S.; Jetten, A. M.
  3. Journal of Biological Chemistry. 2002 277(12): 10139-10149.
  1. 17.   Xmeis1, a protooncogene involved in specifying neural crest cell fate in Xenopus embryos
  2. Maeda, R.; Mood, K.; Jones, T. L.; Aruga, J.; Buchberg, A. M.; Daar, I. O.
  3. Oncogene. 2001 20(11): 1329-1342.
  1. 18.   Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis
  2. Heyer, J.; Escalante-Alcalde, D.; Lia, M.; Boettinger, E.; Edelmann, W.; Stewart, C. L.; Kucherlapati, R.
  3. Proceedings of the National Academy of Sciences of the United States of America. 1999 96(22): 12595-12600.
  1. 19.   Cancer as a complex developmental disorder - Nineteenth Cornelius P. Rhoads Memorial Award Lecture
  2. Dean, M.
  3. Cancer Research. 1998 58(24): 5633-5636.
  1. 20.   Using Ec and Es Cell Culture to Study Early Development - Recent Observations On Indian Hedgehog and Bmps
  2. Grabel, L.; Becker, S.; Lock, L.; Maye, P.; Z, ers
  3. International Journal of Developmental Biology. 1998 42(7 Special Issue SI): 917-925.
  1. 21.   Towards a Unified Model of Tumor Suppression - Lessons Learned From the Human Patched Gene
  2. Dean, M.
  3. Biochimica et Biophysica Acta - Reviews on Cancer. 1997 1332(2): M 43-M 52.
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