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  1. 1.   Early Intervention in STAT3 Dominant-Negative Disease
  2. An, Zixiao Annie; Williams, Kelli W; Urban,Amanda; Ali, Sania; Roy, Susan; Lafeer, Christine; Heimall, Jennifer; Dimitriades, Victoria R; Davis, Joie; Kong, Heidi H; Cowen, Edward W; Holland, Steven M; Freeman, Alexandra F
  3. The Journal of Allergy and Clinical Immunology. In Practice. 2023, Sep 06;
  1. 2.   Dupilumab Therapy in STAT3 Deficient Hyper IgE Syndrome
  2. Nataraj, Pavan; Bergerson, Jenna; Kumar, Shashi; Risma, Kimberly; Sabo, Michelle; Urban,Amanda; Freeman, Alexandra
  3. Journal of Clinical Immunology. 2021, Apr; 41(Suppl 1): S9-S10.
  1. 3.   An Unusual Pattern of Premature Cervical Spine Degeneration in STAT3-LOF
  2. Mitchell, Amelia L.; Urban,Amanda; Freeman, Alexandra F.; Hammoud, Dima A.
  3. Journal of clinical immunology. 2021, Apr; 41(3): 576-584.
  1. 4.   HIV proviral DNA integration can drive T cell growth ex vivo
  2. Yoon, John K; Holloway, Joseph R; Wells,Daria; Kaku, Machika; Jetton, David; Brown, Rebecca; Coffin, John M
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, Dec 29; 117(52): 32880-32882.
  1. 5.   C-CBL is required for inhibition of angiogenesis through modulating JAK2/STAT3 activity in ROP development
  2. Chen, Shimei; Sun, Qiao; Sun, Dandan; Willette Brown,Jami; Anderson,Matthew; Gu, Qing; Lewandoski,Mark; Hu, Yinling; Zhu,Feng; Wei, Fang; Zhang, Jian
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020, DEC; 132: 110856.
  1. 6.   Spontaneous Gastrointestinal Perforations in STAT3-Deficient Hyper-IgE Syndrome
  2. Bhattacharya, Sumona; Williamson, Hastings; Urban,Amanda; Heller, Theo; Freeman, Alexandra F
  3. Journal of clinical immunology. 2020, Sep 11;
  1. 7.   Inhibition of murine hepatoma tumor growth by cryptotanshinone involves TLR7-dependent activation of macrophages and induction of adaptive antitumor immune defenses
  2. Han, Zhen; Liu, Shuo; Lin, Hongsheng; Trivett,Anna; Hannifin,Sean; Yang,De; Oppenheim,Joost
  3. Cancer immunology, immunotherapy : CII. 2019, JUL; 68(7): 1073-1085.
  1. 8.   IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective gamma-chain cytokines, decreases leukemic T-cell viability
  2. Wang, T. Tiffany; Yang, Jun; Zhang, Yong; Zhang,Meili; Dubois, Sigrid; Conlon, Kevin C.; Tagaya, Yutaka; Hamele, Cait E.; Dighe, Shubha; Olson, Thomas L.; Feith, David J.; Azimi, Nazli; Waldmann, Thomas A.; Loughran, Thomas P.
  3. Leukemia. 2019, May; 33(5): 1243-1255.
  1. 9.   Intestinal non-canonical NF kappa B signaling shapes the local and systemic immune response
  2. Ramakrishnan, Sadeesh K.; Zhang, Huabing; Ma, Xiaoya; Jung, Inkyung; Schwartz, Andrew J.; Triner, Daniel; Devenport, Samantha N.; Das, Nupur K.; Xue, Xiang; Zeng, Melody Y.; Hu,Yinling; Mortensen, Richard M.; Greenson, Joel K.; Cascalho, Marilia; Wobus, Christiane E.; Colacino, Justin A.; Nunez, Gabriel; Rui, Liangyou; Shah, Yatrik M.
  3. Nature communications. 2019, Feb 8; 10(1):
  1. 10.   Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma
  2. Lu, Li; Zhu, Fen; Zhang, Meili; Li, Yangguang; Drennan, Amanda C; Kimpara, Shuichi; Rumball, Ian; Selzer, Christopher; Cameron, Hunter; Kellicut, Ashley; Kelm, Amanda; Wang, Fangyu; Waldmann, Thomas A; Rui, Lixin
  3. Proceedings of the National Academy of Sciences of the United States of America. 2018, Jan 16; 115(3): E498-E505.
  1. 11.   Inhibitors of STAT3, ß-catenin, and IGF-1R sensitize mouse PIK3CA mutant breast cancer to PI3K inhibitors
  2. Merino, Vanessa F; Cho, Soonweng; Liang, Xiaohui; Park, Sunju; Jin, Kideok; Chen, Qian; Pan, Duojia; Zahnow, Cynthia A; Rein, Alan; Sukumar, Saraswati
  3. Molecular Oncology. 2017, Mar 15; 11(5): 552-566.
  1. 12.   Transforming Growth Factor-ß (TGF-ß) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.
  2. Tang, Liu-Ya; Heller, Mary; Meng, Zhaojing; Yu, Li-Rong; Tang, Yi; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2017, Mar 10; 292(10): 4302-4312.
  1. 13.   Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis
  2. Henrich, C. J.; Thomas, C. L.; Brooks, A. D.; Booth, N. L.; Lowery, E. M.; Pompei, R. J.; McMahon, J. B.; Sayers, T. J.
  3. Apoptosis. 2012, Jan; 17(1): 79-89.
  1. 14.   IKK alpha represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin
  2. Liu, B.; Willette-Brown, J.; Liu, S.; Chen, X.; Fischer, S. M.; Hu, Y.
  3. Cell Death and Differentiation. 2011, Dec; 18(12): 1854-1864.
  1. 15.   In Vivo Consequences of Liver-Specific Interleukin-22 Expression in Mice: Implications for Human Liver Disease Progression
  2. Park, O.; Wang, H.; Weng, H. L.; Feigenbaum, L.; Li, H.; Yin, S.; Ki, S. H.; Yoo, S. H.; Dooley, S.; Wang, F. S.; Young, H. A.; Gao, B.
  3. Hepatology. 2011, Jul; 54(1): 252-261.
  1. 16.   Coronary Artery Abnormalities in Hyper-IgE Syndrome
  2. Freeman, A. F.; Avila, E. M.; Shaw, P. A.; Davis, J.; Hsu, A. P.; Welch, P.; Matta, J. R.; Hadigan, C.; Pettigrew, R. I.; Holland, S. M.; Gharib, A. M.
  3. Journal of Clinical Immunology. 2011, Jun; 31(3): 338-345.
  1. 17.   STAT1 activation regulates proliferation and differentiation of renal progenitors
  2. Wang, H.; Yang, Y.; Sharma, N.; Tarasova, N. I.; Timofeeva, O. A.; Winkler-Pickett, R. T.; Tanigawa, S.; Perantoni, A. O.
  3. Cellular Signalling. 2010, Nov; 22(11): 1717-1726.
  1. 18.   Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells
  2. Mathews, L. A.; Hurt, E. M.; Zhang, X. H.; Farrar, W. L.
  3. Molecular Cancer. 2010, Oct; 9: 17.
  1. 19.   Interleukin-26: An IL-10-related cytokine produced by Th17 cells
  2. Donnelly, R. P.; Sheikh, F.; Dickensheets, H.; Savan, R.; Young, H. A.; Walter, M. R.
  3. Cytokine & Growth Factor Reviews. 2010, Oct; 21(5): 393-401.
  1. 20.   Pathogenesis of Hyper IgE Syndrome
  2. Heimall, J.; Freeman, A.; Holland, S. M.
  3. Clinical Reviews in Allergy & Immunology. 2010, Feb; 38(1): 32-38.
  1. 21.   The Neurofibromatosis Type 1 Tumor Suppressor Controls Cell Growth by Regulating Signal Transducer and Activator of Transcription-3 Activity In vitro and In vivo
  2. Banerjee, S.; Byrd, J. N.; Gianino, S. M.; Harpstrite, S. E.; Rodriguez, F. J.; Tuskan, R. G.; Reilly, K. M.; Piwnica-Worms, D. R.; Gutmann, D. H.
  3. Cancer Research. 2010, Feb; 70(4): 1356-1366.
  1. 22.   Clinical Manifestations, Etiology, and Pathogenesis of the Hyper-IgE Syndromes
  2. Freeman, A. F.; Holland, S. M.
  3. Pediatric Research. 2009 65(5): 32R-37R.
  1. 23.   Toll-like Receptor 9 Activation of Signal Transducer and Activator of Transcription 3 Constrains Its Agonist-Based Immunotherapy
  2. Kortylewski, M.; Kujawski, M.; Herrmann, A.; Yang, C. M.; Wang, L.; Liu, Y.; Salcedo, R.; Yu, H.
  3. Cancer Research. 2009 69(6): 2497-2505.
  1. 24.   IFN alpha and IFN lambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
  2. Maher, S. G.; Sheikh, F.; Scarzello, A. J.; Romero-Weaver, A. L.; Baker, D. P.; Donnelly, R. P.; Gamero, A. M.
  3. Cancer Biology & Therapy. 2008 7(7): 1109-1115.
  1. 25.   Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation
  2. Qin, H. R.; Kim, H. J.; Kim, J. Y.; Hurt, E. M.; Klarmann, G. J.; Kawasaki, B. T.; Serrat, M.; Farrar, W. L.
  3. Cancer Research. 2008 68(19): 7736-7741.
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