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  1. 1.   A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity
  2. Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo,Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A
  3. Protein Science : a publication of the Protein Society. 2025, Mar; 34(3): e70069.
  1. 2.   Co-incubation of Short Amphiphilic Peptides with Dicer Substrate RNAs Results in ß-Sheet Fibrils for Enhanced Gene Silencing in Cancer Cells
  2. Gupta, Kshitij; Parlea, Lorena; Puri,Anu; Smith, Katelyn; Puri,Anu; Bergman, Joseph T; Kim, Taejin; Shapiro,Bruce
  3. RNA Nanomed. 2024, Dec; 1(1): 61-78.
  1. 3.   Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydroptein pyrophosphokinase: Toward cell permeability
  2. Shi,Genbin; Shaw,Gary; Ji,Xinhua
  3. Bioorganic & Medicinal Chemistry Letters. 2024, Sep 25; 129977.
  1. 4.   Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1
  2. Zhao,Xue Zhi; Wang, Wenjie; Lountos,George; Tropea, Joseph E; Needle,Danielle; Pommier, Yves; Burke,Terrence
  3. Frontiers in Chemistry. 2022, Aug 16; 10: 910953.
  1. 5.   Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
  2. Robey, Robert W.; Robinson, Andrea N.; Ali-Rahmani, Fatima; Huff, Lyn M.; Lusvarghi, Sabrina; Vahedi, Shahrooz; Hotz, Jordan M.; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Edmondson,Elijah; Lee, Tobie D.; Roth, Jacob S.; Lee, Olivia W.; Shen, Min; Tanner, Kandice; Hall, Matthew D.; Ambudkar, Suresh; Gottesman, Michael M.
  3. SCIENTIFIC REPORTS. 2021, Dec 17; 11(1):
  1. 6.   Molecular basis for redox control by the human cystine/glutamate antiporter system xc(-)
  2. Parker, Joanne L.; Deme,Justin; Kolokouris, Dimitrios; Kuteyi, Gabriel; Biggin, Philip C.; Lea,Susan; Newstead, Simon
  3. Nature Communications. 2021, Dec 8; 12(1):
  1. 7.   Specificity of the HIV-1 Protease on Substrates Representing the Cleavage Site in the Proximal Zinc-Finger of HIV-1 Nucleocapsid Protein
  2. Motyan, Janos Andras; Miczi, Mario; Oroszlan, Stephen; Tozser, Jozsef
  3. Viruses. 2021, Jun; 13(6):
  1. 8.   Covalent Small Molecule Immunomodulators Targeting the Protease Active Site
  2. Kim,Hong-Rae; Tagirasa,Ravichandra; Yoo,Euna
  3. Journal of medicinal chemistry. 2021, May 13; 64(9): 5291-5322.
  1. 9.   Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding
  2. Shi,Genbin; Shaw,Gary; Zhu, Fengxia; Tarasov,Sergey; Ji,Xinhua
  3. Bioorganic & Medicinal Chemistry. 2021, Jan 1; 29: 115847.
  1. 10.   Dual-Target Inhibitors of the Folate Pathway Inhibit Intrinsically Trimethoprim-Resistant DfrB Dihydrofolate Reductases
  2. Toulouse, Jacynthe L; Shi,Genbin; Lemay-St-Denis, Claudèle; Ebert, Maximilian C C J C; Deon, Daniel; Gagnon, Marc; Ruediger, Edward; Saint-Jacques, Kévin; Forge, Delphine; Vanden Eynde, Jean Jacques; Marinier, Anne; Ji,Xinhua; Pelletier, Joelle N
  3. ACS medicinal chemistry letters. 2020, Nov 12; 11(11): 2261-2267.
  1. 11.   dagLogo: An R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data
  2. Ou, Jianhong; Liu, Haibo; Nirala, Niraj K.; Stukalov, Alexey; Acharya,Usha; Green, Michael R.; Zhu, Lihua Julie
  3. PLOS ONE. 2020, NOV 6; 15(11):
  1. 12.   Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria
  2. Strzelczyk,Pawel; Zhang,Di; Dyba,Marzena; Wlodawer,Alexander; Lubkowski,Jacek
  3. SCIENTIFIC REPORTS. 2020, OCT 15; 10(1):
  1. 13.   Structural Insights into APOBEC3-Mediated Lentiviral Restriction
  2. Delviks-Frankenberry, Krista A.; Desimmie, Belete A.; Pathak,Vinay
  3. Viruses. 2020, JUN; 12(6):
  1. 14.   Mechanism of Catalysis by L-Asparaginase
  2. Lubkowski,Jacek; Vanegas, Juan Manuel; Chan, Wai-Kin; Lorenzi, Philip L.; Weinstein, John N.; Sukharev, Sergei; Fushman, David; Rempe, Susan B.; Anishkin, Andriy; Wlodawer,Alexander
  3. BIOCHEMISTRY. 2020, MAY 26; 59(20): 1927-1945.
  1. 15.   Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
  2. Byun, Jung S; Park, Samson; Yi, Dae Ik; Shin, Jee-Hye; Hernandez, Sara Gil; Hewitt, Stephen M; Nicklaus,Marc; Peach,Megan; Guasch, Laura; Tang, Binwu; Wakefield, Lalage M; Yan, Tingfen; Caban, Ambar; Jones, Alana; Kabbout, Mohamed; Vohra, Nasreen; Nápoles, Anna María; Singhal, Sandeep; Yancey, Ryan; De Siervi, Adriana; Gardner, Kevin
  3. Cell death & disease. 2019, Sep 18; 10(10): 689.
  1. 16.   Farnesyltransferase-Mediated Delivery of a Covalent Inhibitor Overcomes Alternative Prenylation to Mislocalize K-Ras
  2. Novotny, Chris J.; Hamilton, Gregory L.; McCormick, Frank; Shokat, Kevan M.
  3. ACS CHEMICAL BIOLOGY. 2017, Jul; 12(7): 1956-1962.
  1. 17.   Structure of a eukaryotic RNase III postcleavage complex reveals a double-ruler mechanism for substrate selection
  2. Liang, Y. H.; Lavoie, M.; Comeau, M. A.; Abou Elela, S.; Ji, X.
  3. Molecular Cell. 2014, 8-May; 54(3): 431-44.
  1. 18.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 19.   Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties
  2. Shi, G. B.; Shaw, G.; Liang, Y. H.; Subburaman, P.; Li, Y.; Wu, Y.; Yan, H. G.; Ji, X. H.
  3. Bioorganic & Medicinal Chemistry. 2012, Jan; 20(1): 47-57.
  1. 20.   Controlled biodegradation of Self-assembling beta-hairpin Peptide hydrogels by proteolysis with matrix metalloproteinase-13
  2. Giano, M. C.; Pochan, D. J.; Schneider, J. P.
  3. Biomaterials. 2011, Sep; 32(27): 6471-6477.
  1. 21.   Oxime-Based Click Chemistry in the Development of 3-Isoxazolecarboxylic Acid Containing Inhibitors of Yersinia pestis Protein Tyrosine Phosphatase, YopH
  2. Bahta, M.; Burke, T. R.
  3. Chemmedchem. 2011, Aug; 6(8): 1363-1370.
  1. 22.   Structure of human dual-specificity phosphatase 27 at 2.38 angstrom resolution
  2. Lountos, G. T.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2011, May; 67: 471-479.
  1. 23.   Role of Protein Conformational Dynamics in the Catalysis by 6-Hydroxymethyl-7, 8-Dihydropterin Pyrophosphokinase
  2. Yan, H. G.; Ji, X. H.
  3. Protein and Peptide Letters. 2011, Apr; 18(4): 328-335.
  1. 24.   Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
  2. Aggarwal, M.; Sommers, J. A.; Shoemaker, R. H.; Brosh, R. M.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, Jan; 108(4): 1525-1530.
  1. 25.   Small Molecule Inhibitors as Countermeasures for Botulinum Neurotoxin Intoxication
  2. Li, B.; Peet, N. P.; Butler, M. M.; Burnett, J. C.; Moir, D. T.; Bowlin, T. L.
  3. Molecules. 2011, Jan; 16(1): 202-220.
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