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  1. 1.   TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
  2. Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett,Stephen; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley
  3. Cancer Letters. 2025, Jun 28; 620: 217692.
  1. 2.   Aberrant Wnt/ß-catenin signaling in the mesenchymal stem cells of LZTFL1-depleted mice leads to increased adipogenesis, with implications for obesity
  2. Badralmaa,Yunden; Natarajan,Ven
  3. The Journal of Biological Chemistry. 2024, Dec 09; 108057.
  1. 3.   The structure of the IL-11 signalling complex provides insight into receptor variants associated with craniosynostosis
  2. Sentosa, Darlene D; Metcalfe,Riley; Sims, Natalie A; Putoczki, Tracy L; Griffin, Michael D W
  3. The FEBS Journal. 2024, Oct 27;
  1. 4.   Human Cripto-1 and Cripto-3 Protein Expression in Normal and Malignant Settings That Conflicts with Established Conventions
  2. Cuttitta,Frank; García-Sanmartín, Josune; Feng,Yang; Sunday, Mary Elizabeth; Kim, Young S; Martínez, Alfredo
  3. Cancers. 2024, Oct 23; 16(21):
  1. 5.   Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal
  2. Rink,Connie; Kroupa, Tomas; Rein,Alan; Datta,Siddhartha
  3. Viruses. 2024, Sep 25; 16(10): 1517.
  1. 6.   Novel Arf1 Inhibitors Drive Cancer Stem Cell Aging and Potentiate Anti-Tumor Immunity
  2. Wang, Yuetong; Li, Qiaoming; Ding, Yahui; Luo, Chenfei; Yang, Jun; Wang, Na; Jiang, Ning; Yao, Tiange; Wang, Guohao; Shi, Guoming; Hou, Steven X
  3. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2024, Sep 03; e2404442.
  1. 7.   K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins
  2. Magits, Wout; Steklov, Mikhail; Jang,Hyunbum; Sewduth, Raj N; Florentin, Amir; Lechat, Benoit; Sheryazdanova, Aidana; Zhang, Mingzhen; Simicek, Michal; Prag, Gali; Nussinov,Ruth; Sablina, Anna
  3. The EMBO Journal. 2024, Jun 10;
  1. 8.   The Janus kinase 1 is critical for pancreatic cancer initiation and progression
  2. Shrestha, Hridaya; Rädler, Patrick D; Dennaoui, Rayane; Wicker, Madison N; Rajbhandari, Nirakar; Sun, Yunguang; Peck, Amy R; Vistisen, Kerry; Triplett, Aleata A; Beydoun, Rafic; Sterneck,Esta; Saur, Dieter; Rui, Hallgeir; Wagner, Kay-Uwe
  3. Cell Reports. 2024, May 10; 43(5): 114202.
  1. 9.   Disruption of Ca2+/calmodulin:KSR1 interaction lowers ERK activation
  2. Thines, Louise; Jang,Hyunbum; Li, Zhigang; Sayedyahossein, Samar; Maloney, Ryan; Nussinov,Ruth; Sacks, David B
  3. Protein Science : a publication of the Protein Society. 2024, May; 33(5): e4982.
  1. 10.   SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities
  2. Liu,Yonglan; Zhang,Wengang; Jang,Hyunbum; Nussinov,Ruth
  3. Cellular and Molecular Life Sciences : CMLS. 2023, Dec 12; 81(1): 5.
  1. 11.   Revealing KRas4b topology on the membrane surface
  2. Shree, Shweta; McLean, Mark A; Stephen,Andy; Sligar, Stephen G
  3. Biochemical and Biophysical Research Communications. 2023, Oct 20; 678: 122-127.
  1. 12.   Protocol for measuring BRAF autoinhibition in live cells using a proximity-based NanoBRET assay
  2. Smith,Russell; Morrison,Deborah
  3. STAR Protocols. 2023, Aug 16; 4(3): 102461.
  1. 13.   GSK-3a/ß and MEK inhibitors assist the microenvironment of tumor initiation
  2. Hassan, Ghmkin; Afify, Said M; Zahra, Maram H; Nawara, Hend M; Kumon, Kazuki; Iwasaki, Yoshiaki; Salomon,David; Seno, Akimasa; Seno, Masaharu
  3. Cytotechnology. 2023, Jun; 75(3): 243-253.
  1. 14.   IL-4, IL-13 and IFN-gamma induced genes in highly purified human neutrophils
  2. Kummola, Laura; Salomaa, Tanja; Ortutay, Zsuzsanna; Savan, Ram; Young,Howard; Junttila, Ilkka S
  3. Cytokine. 2023, Feb 19; 164: 156159.
  1. 15.   Stabilization of E-cadherin adhesions by COX-2/GSK3ß signaling is a targetable pathway in metastatic breast cancer
  2. Balamurugan, Kuppusamy; Poria, Dipak K; Sehareen, Saadiya W; Krishnamurthy, Savitri; Tang, Wei; McKennett,Lois; Padmanaban, Veena; Czarra,Kelli; Ewald, Andrew J; Ueno, Naoto T; Ambs, Stefan; Sharan, Shikha; Sterneck,Esta
  3. JCI Insight. 2023, Feb 09; 8(6):
  1. 16.   Double knockin mice show NF-?B trajectories in immune signaling and aging
  2. Rahman, Shah Md Toufiqur; Aqdas, Mohammad; Martin, Erik W; Tomassoni Ardori,Francesco; Songkiatisak, Preeyaporn; Oh, Kyu-Seon; Uderhardt, Stefan; Yun, Sangwon; Claybourne, Quia C; McDevitt, Ross A; Greco, Valentina; Germain, Ronald N; Tessarollo, Lino; Sung, Myong-Hee
  3. Cell Reports. 2022, Nov 22; 41(8): 111682.
  1. 17.   A Heterozygous Gain-of-Function Variant in IKBKB Associated with Autoimmunity and Autoinflammation
  2. Sacco, Keith; Kuehn, Hye Sun; Kawai, Tomoki; Alsaati, Nouf; Smith, Lauren; Davila, Blachy; Bundy, Vanessa; Kuhns,Doug; Dobbs, Kerry; Delmonte, Ottavia; Notarangelo, Luigi D; Rosenzweig, Sergio D; Keller, Michael D
  3. Journal of Clinical Immunology. 2022, Nov 15;
  1. 18.   Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
  2. Zhu, Jianjian; Patel,Rashmi; Trofka, Anna; Harfe, Brian D; Mackem,Susan
  3. Developmental Cell. 2022, Aug 13; 57(17): 2048-2062.
  1. 19.   Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation
  2. Abulwerdi, Fardokht; Fatehi, Farzad; Manfield, Iain W; Le Grice,Stuart; Schneekloth,Jay; Twarock, Reidun; Stockley, Peter G; Patel, Nikesh
  3. Data in Brief. 2022, Jun; 42: 108206.
  1. 20.   ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
  2. Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Merna Timaul, Neilawattie; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M; Jänne, Pasi A; McCormick, Frank; Yao, Zhan; Rosen, Neal
  3. Molecular Cell. 2022, May 14;
  1. 21.   Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands
  2. Patel, Nikesh; Abulwerdi, Fardokht; Fatehi, Farzad; Manfield, Iain; Le Grice,Stuart; Schneekloth,Jay; Twarock, Reidun; Stockley, Peter G
  3. Journal of Molecular Biology. 2022, Mar 24; 167557.
  1. 22.   The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery
  2. Kontaridis, Maria I; Roberts, Amy E; Schill, Lisa; Schoyer, Lisa; Stronach, Beth; Andelfinger, Gregor; Aoki, Yoko; Axelrad, Marni E; Bakker, Annette; Bennett, Anton M; Broniscer, Alberto; Castel, Pau; Chang, Caitlin A; Cyganek, Lukas; Das, Tirtha K; den Hertog, Jeroen; Galperin, Emilia; Garg, Shruti; Gelb, Bruce D; Gordon, Kristiana; Green, Tamar; Gripp, Karen W; Itkin, Maxim; Kiuru, Maija; Korf, Bruce R; Livingstone, Jeff R; López-Juárez, Alejandro; Magoulas, Pilar L; Mansour, Sahar; Milner, Theresa; Parker, Elisabeth; Pierpont, Elizabeth I; Plouffe, Kevin; Rauen, Katherine A; Shankar, Suma P; Smith, Shane B; Stevenson, David A; Tartaglia, Marco; Van, Richard; Wagner,Morgan; Ware, Stephanie M; Zenker, Martin
  3. American Journal of Medical Genetics. Part A. 2022, Mar 09;
  1. 23.   Complete Genome Sequence of Herpes Simplex Virus 2 Strain G
  2. Chang,Weizhong; Jiao, Xiaoli; Sui,Hongyan; Goswami, Suranjana; Sherman,Brad; Fromont,Caroline; Caravaca-Guasch,Juan Manuel; Tran,Bao; Imamichi,Tomozumi
  3. Viruses. 2022, Mar 05; 14(3):
  1. 24.   IKKa-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines
  2. Song, Na-Young; Li,Xin; Ma, Buyong; Willette-Brown, Jami; Zhu,Feng; Jiang, Chengfei; Su,Ling; Shetty,Jyoti; Zhao,Yongmei; Shi,Gongping; Banerjee, Sayantan; Wu,Xiaolin; Tran,Bao; Nussinov,Ruth; Karin, Michael; Hu,Yinling
  3. Proceedings of the National Academy of Sciences of the United States of America. 2022, Feb 08; 119(6): e2120956119.
  1. 25.   Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development
  2. Sun,Jian; Yoon,Jaeho; Lee,Moonsup; Lee,Hyun Kyung; Hwang,Rich Yooseok; Daar,Ira
  3. Cell Reports. 2022, Feb 01; 38(5):
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