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  1. 1.   Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
  2. Shi,Scarlett; Chiramel, Abhilash I; Li, Tiansheng; Lai, Kin Kui; Kenney, Adam D; Zani, Ashley; Eddy, Adrian C; Majdoul,Saliha; Zhang, Lizhi; Dempsey, Tirhas; Beare, Paul A; Kar, Swagata; Yewdell, Jonathan W; Best, Sonja M; Yount, Jacob S; Compton,Alex
  3. The Journal of Clinical Investigation. 2022, Dec 15; 132(24):
  1. 2.   Safety and immunogenicity of an HIV-1 prefusion-stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label, randomized, dose-escalation, phase 1 clinical trial
  2. Houser, Katherine V; Gaudinski, Martin R; Happe, Myra; Narpala, Sandeep; Verardi, Raffaello; Sarfo, Edward K; Corrigan, Angela R; Wu, Richard; Rothwell, Ro Shauna; Novik, Laura; Hendel, Cynthia S; Gordon, Ingelise J; Berkowitz, Nina M; Cartagena, Cora Trelles; Widge, Alicia T; Coates, Emily E; Strom, Larisa; Hickman, Somia; Conan-Cibotti, Michelle; Vazquez, Sandra; Trofymenko, Olga; Plummer, Sarah; Stein, Judy; Case,Christopher; Nason, Martha; Biju, Andrea; Parchment, Danealle K; Changela, Anita; Cheng, Cheng; Duan, Hongying; Geng, Hui; Teng, I-Ting; Zhou, Tongqing; O'Connell, Sarah; Barry, Chris; Carlton, Kevin; Gall, Jason G; Flach, Britta; Doria-Rose, Nicole A; Graham, Barney S; Koup, Richard A; McDermott, Adrian B; Mascola, John R; Kwong, Peter D; Ledgerwood, Julie E
  3. EClinicalMedicine. 2022, Jun; 48: 101477.
  1. 3.   A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation
  2. Gulla, Krishana; Cibelli, Nicole; Cooper, Jonathan W.; Fuller, Haley C.; Schneiderman, Zachary; Witter, Sara; Zhang, Yaqiu; Changela, Anita; Geng, Hui; Hatcher, Christian; Narpala, Sandeep; Tsybovsky,Yaroslav; Zhang, Baoshan; McDermott, Adrian B.; Kwong, Peter D.; Gowetski, Daniel B.
  3. Vaccine. 2021, Jun 8; 39(25): 3379-3387.
  1. 4.   Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
  2. Su, Hua; Yang, Fei; Fu, Rao; Li,Xin; French, Randall; Mose, Evangeline; Pu, Xiaohong; Trinh, Brittney; Kumar, Avi; Liu, Junlai; Antonucci, Laura; Todoric, Jelena; Liu, Yuan; Hu,Yinling; Diaz-Meco, Maria T.; Moscat, Jorge; Metallo, Christian M.; Lowy, Andrew M.; Sun, Beicheng; Karin, Michael
  3. Cancer Cell. 2021, May 10; 39(5): 678-693.e11.
  1. 5.   Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
  2. Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler,John; Wilson,Jennifer; Corona, Angela; Le Grice,Stuart; Tramontano, Enzo
  3. Journal of enzyme inhibition and medicinal chemistry. 2020, Dec; 35(1): 1953-1963.
  1. 6.   Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains
  2. Rawi, Reda; Rutten, Lucy; Lai, Yen-Ting; Olia, Adam S; Blokland, Sven; Juraszek, Jarek; Shen, Chen-Hsiang; Tsybovsky,Yaroslav; Verardi, Raffaello; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Chuang, Gwo-Yu; Kwong, Peter D; Langedijk, Johannes P M
  3. Cell reports. 2020, Nov 24; 33(8): 108432.
  1. 7.   The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release
  2. Waheed,Abdul; Swiderski, Maya; Khan, Ali; Gitzen, Ariana; Majadly, Ahlam; Freed,Eric
  3. The Journal of Biological Chemistry. 2020, MAY 22; 295(21): 7327-7340.
  1. 8.   A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
  2. Endoh, Mitsuhiro; Baba, Masaya; Endoh, Tamie; Hirayama, Akiyoshi; Nakamura-Ishizu, Ayako; Umemoto, Terumasa; Hashimoto, Michihiro; Nagashima,Kunio; Soga, Tomoyoshi; Lang, Martin; Schmidt,Laura; Linehan, W Marston; Suda, Toshio
  3. Cell reports. 2020, Feb 11; 30(6): 1823-1834.e5.
  1. 9.   Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids
  2. Frias, Maria A.; Mukhopadhyay,Suman; Lehman, Elyssa; Walasek, Aleksandra; Utter, Matthew; Menon, Deepak; Foster, David A.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, JAN 3; 295(1): 263-274.
  1. 10.   Elements in the ? Immunity Region Regulate Phage Development: Beyond the "Genetic Switch"
  2. Thomason,Lynn; Morrill, Kathleen; Murray, Gillian; Court,Carolyn; Shafer, Brenda; Schneider,Tom; Court,Don
  3. Molecular microbiology. 2019, DEC; 112(6): 1798-1813.
  1. 11.   Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation
  2. Hong,Jaewoo; Wuest, Todd R; Min,Yongfen; Lin,Charles
  3. Cancers. 2019, Nov; 11(11): pii: E1653..
  1. 12.   Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells
  2. Bussi, Claudio; Peralta Ramos, Javier M; Arroyo, Daniela S; Gallea, Jose I; Ronchi, Paolo; Kolovou, Androniki; Wang, Jiming; Florey, Oliver; Celej, Maria S; Schwab, Yannick; Ktistakis, Nicholas T; Iribarren, Pablo
  3. Journal of cell science. 2018, Nov 30; 131(23): pii: jcs.226241.
  1. 13.   Synthesis of amide isosteres of schweinfurthin-based stilbenes
  2. Stockdale, David P; Beutler, John; Wiemer, David F
  3. Bioorganic & medicinal chemistry. 2017, Oct 15; 25(20): 5483-5489.
  1. 14.   Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.
  2. Ritt, Daniel A; Abreu-Blanco, María T; Bindu, Lakshman; Durrant, David E; Zhou, Ming; Specht, Suzanne I; Stephen, Andrew G; Holderfield, Matthew; Morrison, Deborah K
  3. Molecular cell. 2016, 2016 Dec 01; 64(5): 875-887.
  1. 15.   Structural studies of vacuolar plasmepsins
  2. Bhaumik, P.; Gustchina, A.; Wlodawer, A.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2012, Jan; 1824(1): 207-223.
  1. 16.   Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum
  2. Bhaumik, P.; Horimoto, Y.; Xiao, H. G.; Miura, T.; Hidaka, K.; Kiso, Y.; Wlodawer, A.; Yada, R. Y.; Gustchina, A.
  3. Journal of Structural Biology. 2011, Jul; 175(1): 73-84.
  1. 17.   Ion-Abrasion Scanning Electron Microscopy Reveals Surface-Connected Tubular Conduits in HIV-Infected Macrophages
  2. Bennett, A. E.; Narayan, K.; Shi, D.; Hartnell, L. M.; Gousset, K.; He, H. F.; Lowekamp, B. C.; Yoo, T. S.; Bliss, D.; Freed, E. O.; Subramaniam, S.
  3. Plos Pathogens. 2009 5(9):
  1. 18.   Application of a Flow Cytometric Cytotoxicity Assay for Monitoring Cancer Vaccine Trials
  2. Zaritskaya, L.; Shafer-Weaver, K. A.; Gregory, M. K.; Strobl, S. L.; Baseler, M.; Malyguine, A.
  3. Journal of Immunotherapy. 2009 32(2): 186-194.
  1. 19.   The big brain aquaporin is required for endosome maturation and notch receptor trafficking
  2. Kanwar, R.; Fortini, M. E.
  3. Cell. 2008 133(5): 852-863.
  1. 20.   Synthesis and biological evaluation of 2-amino-3-(3 ',4 ',5 '-trimethoxyphenyisulfonyl)-5-aryl thiophenes as a new class of antitubulin agents
  2. Romagnoli, R.; Baraldi, P. G.; Remusat, V.; Carrion, M. D.; Cara, C. L.; Cruz-Lopez, O.; Preti, D.; Fruttarolo, F.; Tabrizi, M. A.; Balzarini, J.; Hamel, E.
  3. Medicinal Chemistry. 2007, Nov; 3(6): 507-512.
  1. 21.   Synthesis and applications of novel bis(ammonium) chiral ionic liquids derived from isomannide
  2. Kumar, V.; Olsen, C. E.; Schaffer, S. J. C.; Parmar, V. S.; Malhotra, S. V.
  3. Organic Letters. 2007, Sep; 9(20): 3905-3908.
  1. 22.   Cellular and tissue distribution of intravenously administered agalsidase alfa
  2. Murray, G. J.; Anver, M. R.; Kennedy, M. A.; Quirk, J. M.; Schiffmann, R.
  3. Molecular Genetics and Metabolism. 2007, Mar; 90(3): 307-312.
  1. 23.   Mouse coat color mutations: From fancy mice to functional genomics
  2. Steingrimsson, E.; Copeland, N. G.; Jenkins, N. A.
  3. Developmental Dynamics. 2006, Sep; 235(9): 2401-2411.
  1. 24.   Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer
  2. Kanao, H.; Enomoto, T.; Kimura, T.; Fujita, M.; Nakashima, R.; Ueda, Y.; Ueno, Y.; Miyatake, T.; Yoshizaki, T.; Buzard, G. S.; Tanigami, A.; Yoshino, K.; Murata, Y.
  3. Cancer Research. 2005, OCT 1; 65(19): 8640-8645.
  1. 25.   Replacing acid alpha-glucosidase in Pompe disease: Recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers
  2. Raben, N.; Fukuda, T.; Gilbert, A. L.; de Jong, D.; Thurberg, B. L.; Mattaliano, R. J.; Meikle, P.; Hopwood, J. J.; Nagashima, K.; Nagaraju, K.; Plotz, P. H.
  3. Molecular Therapy. 2005, JAN; 11(1): 48-56.
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