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  1. 1.   Hypomorphic Rag mutations can cause destructive midline granulomatous disease
  2. De Ravin, S. S.; Cowen, E. W.; Zarember, K. A.; Whiting-Theobald, N. L.; Kuhns, D. B.; Sandler, N. G.; Douek, D. C.; Pittaluga, S.; Poliani, P. L.; Lee, Y. N.; Notarangelo, L. D.; Wang, L.; Alt, F. W.; Kang, E. M.; Milner, J. D.; Niemela, J. E.; Fontana-Penn, M.; Sinal, S. H.; Malech, H. L.
  3. Blood. 2010, Aug; 116(8): 1263-1271.
  1. 2.   Murine Leukemias with Retroviral Insertions at Lmo2 Are Predictive of the Leukemias Induced in SCID-X1 Patients Following Retroviral Gene Therapy
  2. Dave, U. P.; Akagi, K.; Tripathi, R.; Clevel, S. M.; Thompson, M. A.; Yi, M.; Stephens, R.; Downing, J. R.; Jenkins, N. A.; Copeland, N. G.
  3. Plos Genetics. 2009 5(5): 1-13.
  1. 3.   Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus
  2. Liepinsh, D. J.; Kruglov, A. A.; Galimov, A. R.; Shakhov, A. N.; Shebzukhov, Y. V.; Kuchmiy, A. A.; Grivennikov, S. I.; Tumanov, A. V.; Drutskaya, M. S.; Feigenbaum, L.; Kuprash, D. V.; Nedospasov, S. A.
  3. European Journal of Immunology. 2009 39(10): 2906-2915.
  1. 4.   Upregulation of CD4 Expression during MHC Class II-Specific Positive Selection Is Essential for Error-free Lineage Choice
  2. Sarafova, S. D.; Van Laethem, F.; Adoro, S.; Guinter, T.; Sharrow, S. O.; Feigenbaum, L.; Singer, A.
  3. Immunity. 2009 31(3): 480-490.
  1. 5.   Interleukin-7 receptor expression: intelligent design
  2. Mazzucchelli, R.; Durum, S. K.
  3. Nature Reviews Immunology. 2007, Feb; 7(2): 144-154.
  1. 6.   Itch genetically interacts with Notch1 in a mouse autoimmune disease model
  2. Matesic, L. E.; Haines, D. C.; Copeland, N. G.; Jenkins, N. A.
  3. Human Molecular Genetics. 2006, Dec; 15(24): 3485-3497.
  1. 7.   Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
  2. Yu, Q.; Park, J. H.; Doan, L. L.; Erman, B.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2006, JAN 23; 203(1): 165-175.
  1. 8.   Retroviral transduction of IL-7R alpha into IL-7R alpha(-/-) bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia
  2. Jiang, Q.; Li, W. Q.; Aiello, F. B.; Klarmann, K.; Keller, J. R.; Durum, S. K.
  3. Gene Therapy. 2005, DEC; 12(24): 1761-1768.
  1. 9.   Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression
  2. Rodriguez-Galan, M. C.; Bream, J. H.; Farr, A.; Young, H. A.
  3. Journal of Immunology. 2005, MAR 1; 174(5): 2796-2804.
  1. 10.   Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration
  2. Dorshkind, K.; Welniak, L.; Gault, R. A.; Hixon, J.; Montecino-Rodriguez, E.; Horseman, N. D.; Gertner, J. M.; Murphy, W. J.
  3. Clinical Immunology. 2003 109(2): 197-202.
  1. 11.   Bcl11a is essential for normal lymphoid development
  2. Liu, P. T.; Keller, J. R.; Ortiz, M.; Tessarollo, L.; Rachel, R. A.; Nakamura, T.; Jenkins, N. A.; Copeland, N. G.
  3. Nature Immunology. 2003 4(6): 525-532.
  1. 12.   Death and Baxes: mechanisms of lymphotrophic cytokines
  2. Khaled, A. R.; Durum, S. K.
  3. Immunological Reviews. 2003 193(1): 48-57.
  1. 13.   Bax deficiency partially corrects interleukin-7 receptor alpha deficiency
  2. Khaled, A. R.; Li, W. Q.; Huang, J. Q.; Fry, T. J.; Khaled, A. S.; Mackall, C. L.; Muegge, K.; Young, H. A.; Durum, S. K.
  3. Immunity. 2002 17(5): 561-573.
  1. 14.   CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain
  2. Bhandoola, A.; Bosselut, R.; Yu, Q.; Cowan, M. L.; Feigenbaum, L.; Love, P. E.; Singer, A.
  3. European Journal of Immunology. 2002 32(6): 1811-1817.
  1. 15.   Lymphocide: Cytokines and the control of lymphoid homeostasis
  2. Khaled, A. R.; Durum, S. K.
  3. Nature Reviews Immunology. 2002 2(11): 817-830.
  1. 16.   Cutting edge: Histone acetylation and recombination at the TCR gamma locus follows IL-7 induction
  2. Huang, J. Q.; Durum, S. K.; Muegge, K.
  3. Journal of Immunology. 2001 167(11): 6073-6077.
  1. 17.   Strength of signaling by CD4 and CD8 coreceptor tails determines the number but not the lineage direction of positively selected thymocytes
  2. Bosselut, R.; Feigenbaum, L.; Sharrow, S. O.; Singer, A.
  3. Immunity. 2001 14(4): 483-494.
  1. 18.   Growth hormone as an immunomodulating therapeutic agent
  2. Murphy, W. J.; Longo, D. L.
  3. Immunology Today. 2000 21(5): 211-213.
  1. 19.   Pilot Study of the Immunologic Effects of Recombinant Human Growth Hormone and Recombinant Insulin-Like Growth Factor in Hiv-Infected Patients
  2. Nguyen, B. Y.; Clerici, M.; Venzon, D. J.; Bauza, S.; Murphy, W. J.; Longo, D. L.; Baseler, M.; Gesundheit, N.; Broder, S.; Shearer, G.; Yarchoan, R.
  3. Aids. 1998 12(8): 895-904.
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