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  1. 1.   Benzyl Ammonium Carbamates Undergo Two-Step Linker Cleavage and Improve the Properties of Antibody Conjugates
  2. Li,Xiaoyi; Patel,Nimit; Kalen,Joseph; Schnermann,Martin
  3. Angewandte Chemie (International ed. in English). 2024, Dec 18; e202417651.
  1. 2.   Modulating the immunodominance hierarchy of immunoglobulin germline-encoded structural motifs targeting the influenza hemagglutinin stem
  2. Ataca, Sila; Sangesland, Maya; de Paiva Fróes Rocha, Rebeca; Torrents de la Peña, Alba; Ronsard, Larance; Boyoglu-Barnum, Seyhan; Gillespie, Rebecca A; Tsybovsky,Yaroslav; Stephens,Tyler; Moin, Syed M; Lederhofer, Julia; Creanga, Adrian; Andrews, Sarah F; Barnes, Ralston M; Rohrer, Daniel; Lonberg, Nils; Graham, Barney S; Ward, Andrew B; Lingwood, Daniel; Kanekiyo, Masaru
  3. Cell Reports. 2024, Nov 22; 43(12): 114990.
  1. 3.   ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models
  2. Schmid, Sebastian; Russell, Zachary R; Shimura Yamashita,Alex; West, Madeline E; Parrish, Abigail G; Walker, Julia; Rudoy, Dmytro; Yan, James Z; Quist, David C; Gessesse, Betemariyam N; Alvinez, Neriah; Hill, Kimberly D; Anderson,Larry; Cimino, Patrick J; Kumasaka, Debra K; Parchment,Ralph; Holland, Eric C; Szulzewsky, Frank
  3. Cell Reports. 2024, Oct 03; 43(10): 114829.
  1. 4.   Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents
  2. Mariotto, Elena; Canton, Martina; Marchioro, Chiara; Brancale, Andrea; Hamel,Ernest; Varani, Katia; Vincenzi, Fabrizio; De Ventura, Tiziano; Padroni, Chiara; Viola, Giampietro; Romagnoli, Romeo
  3. International Journal of Molecular Sciences. 2024, Jul 09; 25(14):
  1. 5.   The Janus kinase 1 is critical for pancreatic cancer initiation and progression
  2. Shrestha, Hridaya; Rädler, Patrick D; Dennaoui, Rayane; Wicker, Madison N; Rajbhandari, Nirakar; Sun, Yunguang; Peck, Amy R; Vistisen, Kerry; Triplett, Aleata A; Beydoun, Rafic; Sterneck,Esta; Saur, Dieter; Rui, Hallgeir; Wagner, Kay-Uwe
  3. Cell Reports. 2024, May 10; 43(5): 114202.
  1. 6.   Lessons learned: establishing a CLIA-equivalent laboratory for targeted mass spectrometry assays - navigating the transition from research to clinical practice
  2. Han, Chia-Li; Lai, Chi-Ting; Reyes, Aaron James; Yang, Hao-Chin; Lu, Jin-Ying; Shih, Shyang-Rong; Chen, Kuen-Yuan; Hoofnagle, Andrew N; Yu, Sung-Liang; Bocik, William; Hiltke, Tara; Chiu, Huan-Chi; Wan, Ching-Yi; Rodriguez, Henry; Zhang, Victoria; Chen, Yu-Ju
  3. Clinical Proteomics. 2024, Feb 22; 21(1): 12.
  1. 7.   Serum microRNA Profiles and Pathways in Hepatitis B-Associated Hepatocellular Carcinoma: A South African Study
  2. Sartorius, Kurt; Sartorius, Benn; Winkler,Cheryl; Chuturgoon, Anil; Shen,Tsai-Wei; Zhao,Yongmei; An,Ping
  3. International Journal of Molecular Sciences. 2024, Jan 12; 25(2):
  1. 8.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 9.   PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
  2. Torres-Ayuso, Pedro; Katerji,Meghri; Mehlich, Dawid; Lookingbill, Sophia A; Sabbasani, Venkata R; Liou, Hope; Casillas, Andrea L; Chauhan, Shailender S; Serwa, Remigiusz; Rubin,Maxine; Marusiak, Anna A; Swenson, Rolf E; Warfel, Noel A; Brognard,John
  3. Cell Chemical Biology. 2023, Nov 16;
  1. 10.   Methotrexate-based PROTACs as DHFR-specific chemical probes
  2. Rana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L; Lamy, Laurence; Li,Wenqing; Oliphant, Erin; Shrimp, Jonathan H; Rajacharya, Girish H; Tharakan, Ravi; Holland, David O; Whitten, Apryl S; Wilson, Kelli M; Singh, Pankaj K; Durum,Scott; Tao, Dingyin; Rai, Ganesha; Inglese, James
  3. Cell Chemical Biology. 2023, Oct 17;
  1. 11.   Proteogenomic insights suggest druggable pathways in endometrial carcinoma
  2. Dou, Yongchao; Katsnelson, Lizabeth; Gritsenko, Marina A; Hu, Yingwei; Reva, Boris; Hong, Runyu; Wang, Yi-Ting; Kolodziejczak, Iga; Lu, Rita Jui-Hsien; Tsai, Chia-Feng; Bu, Wen; Liu, Wenke; Guo, Xiaofang; An, Eunkyung; Arend, Rebecca C; Bavarva, Jasmin; Chen, Lijun; Chu, Rosalie K; Czekanski, Andrzej; Davoli, Teresa; Demicco, Elizabeth G; DeLair, Deborah; Devereaux, Kelly; Dhanasekaran, Saravana M; Dottino, Peter; Dover, Bailee; Fillmore, Thomas L; Foxall, McKenzie; Hermann, Catherine E; Hiltke, Tara; Hostetter, Galen; Jedryka, Marcin; Jewell, Scott D; Johnson, Isabelle; Kahn, Andrea G; Ku, Amy T; Kumar-Sinha, Chandan; Kurzawa, Pawel; Lazar, Alexander J; Lazcano, Rossana; Lei, Jonathan T; Li, Yi; Liao, Yuxing; Lih, Tung-Shing M; Lin, Tai-Tu; Martignetti, John A; Masand, Ramya P; Matkowski, Rafal; McKerrow, Wilson; Mesri, Mehdi; Monroe, Matthew E; Moon, Jamie; Moore, Ronald J; Nestor, Michael D; Newton, Chelsea; Omelchenko, Tatiana; Omenn, Gilbert S; Payne, Samuel H; Petyuk, Vladislav A; Robles, Ana I; Rodriguez, Henry; Ruggles, Kelly V; Rykunov, Dmitry; Savage, Sara R; Schepmoes, Athena A; Shi, Tujin; Shi, Zhiao; Tan, Jimin; Taylor, Mason; Thiagarajan,Mathangi; Wang, Joshua M; Weitz, Karl K; Wen, Bo; Williams, C M; Wu, Yige; Wyczalkowski, Matthew A; Yi, Xinpei; Zhang, Xu; Zhao, Rui; Mutch, David; Chinnaiyan, Arul M; Smith, Richard D; Nesvizhskii, Alexey I; Wang, Pei; Wiznerowicz, Maciej; Ding, Li; Mani, D R; Zhang, Hui; Anderson, Matthew L; Rodland, Karin D; Zhang, Bing; Liu, Tao; Fenyö, David
  3. Cancer Cell. 2023, Sep 11; 41(9): 1586-1605.e15.
  1. 12.   Investigating the NRAS 5' UTR as a target for small molecules
  2. Balaratnam,Sumirtha; Torrey, Zachary R; Calabrese,Dave; Banco, Michael T; Yazdani, Kamyar; Liang, Xiao; Fullenkamp,Chris; Seshadri,Sri; Holewinski,Ronald; Andresson,Thorkell; Ferré-D'Amaré, Adrian R; Incarnato, Danny; Schneekloth,Jay
  3. Cell Chemical Biology. 2023, Jun 15; 30(6): 643-657.e8.
  1. 13.   Simple monocyclic pyrimidine analogs as microtubule targeting agents binding to the colchicine site
  2. Choudhary, Shruti; Kaku, Krishna; Robles, Andrew J; Hamel,Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry. 2023, Feb 24; 82: 117217.
  1. 14.   Dual B-cell targeting therapy ameliorates autoimmune cholangitis
  2. Zhang, Weici; Shao, Tihong; Leung, Patrick S C; Tsuneyama, Koichi; Heuer, Luke; Young,Howard; Ridgway, William M; Gershwin, M Eric
  3. Journal of Autoimmunity. 2022, Aug 24; 132: 102897.
  1. 15.   Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
  2. Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Budassi, Federica; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Corallo, Diana; Aveic, Sanja; Manfreda, Lorenzo; Mariotto, Elena; Bortolozzi, Roberta; Viola, Giampietro
  3. Pharmaceuticals (Basel, Switzerland). 2022, Aug 21; 15(8):
  1. 16.   BETA: a comprehensive benchmark for computational drug-target prediction
  2. Zong, Nansu; Li,Ning; Wen, Andrew; Ngo, Victoria; Yu, Yue; Huang, Ming; Chowdhury, Shaika; Jiang, Chao; Fu, Sunyang; Weinshilboum, Richard; Jiang, Guoqian; Hunter, Lawrence; Liu, Hongfang
  3. Briefings in Bioinformatics. 2022, Jun 02;
  1. 17.   Aminoflavone upregulates putative tumor suppressor miR-125b-2-3p to inhibit luminal A breast cancer stem cell-like properties
  2. Mavingire, Nicole; Campbell,Petreena; Liu, Tiantian; Wooten, Jonathan; Khan, Salma; Chen, Xin; Matthews, Jason; Wang, Charles; Brantley, Eileen
  3. Precision Clinical Medicine. 2022, Jun; 5(2): pbac008.
  1. 18.   Design, Synthesis, and Biological Evaluation of 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as Microtubule Targeting Agents
  2. Islam, Farhana; Doshi, Arpit; Robles, Andrew J; Quadery, Tasdique M; Zhang, Xin; Zhou, Xilin; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Molecules . 2022, Jan 05; 27(1):
  1. 19.   Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells
  2. Kaczmarczyk,Jan; Roberts,Rhonda; Luke,Brian; Chan,King; Van Wagoner, Carly M; Felder, Robin A; Saul, Richard G; Simona, Colantonio; Blonder,Josip
  3. Oncotarget. 2021, Sep 28; 12(20): 2022-2038.
  1. 20.   Whence CRIPTO: The Reemergence of an Oncofetal Factor in 'Wounds' That Fail to Heal
  2. Freeman, David W.; Sousa, Elisa Rodrigues; Karkampouna, Sofia; Zoni, Eugenio; Gray, Peter C.; Salomon,David; Kruithof-de Julio, Marianna; Spike, Benjamin T.
  3. International journal of molecular sciences. 2021, Sep; 22(18):
  1. 21.   Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition
  2. Whiteaker, Jeffrey R; Wang, Tao; Zhao, Lei; Schoenherr, Regine M; Kennedy, Jacob J; Voytovich, Ulianna; Ivey, Richard G; Huang, Dongqing; Lin, Chenwei; Colantonio,Simona; Caceres,Tessa; Roberts,Rhonda; Knotts,Joseph; Kaczmarczyk,Jan; Blonder,Josip; Reading,Joshua; Richardson, Christopher W; Hewitt, Stephen M; Garcia-Buntley,Stephanie; Bocik,William; Hiltke, Tara; Rodriguez, Henry; Harrington, Elizabeth A; Barrett, J Carl; Lombardi, Benedetta; Marco-Casanova, Paola; Pierce, Andrew J; Paulovich, Amanda G
  3. Cancers. 2021, Aug; 13(15):
  1. 22.   A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope
  2. Raman, Swetha; Buongervino, Samantha N.; Lane, Maria; Zhelev, Doncho; Zhu, Zhongyu; Cui, Hong; Martinez, Benjamin; Martinez, Daniel; Wang, Yanping; Upton, Kristen; Patel, Khushbu; Rathi, Komal S.; Navia, Carmen T.; Harmon, Daniel B.; Li, Yimei; Pawel, Bruce; Dimitrov, Dimiter S.; Maris, John M.; Julien, Jean-Philippe; Bosse, Kristopher R.
  3. Cell reports. Medicine. 2021, Jul 20; 2(7):
  1. 23.   Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing
  2. Blondal, Thorarinn; Gamba, Cristina; Jagd, Lea Moller; Su,Ling; Demirov,Dimiter; Guo,Amber; Johnston, Camille M.; Riising, Eva M.; Wu,Xiaolin; Mikkelsen, Marie J.; Szabova,Ludmila; Mouritzen, Peter
  3. Methods. 2021, Jul; 191: 68-77.
  1. 24.   Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs
  2. LeBlanc, Amy K.; Mazcko, Christina N.; Cherukuri, Aswini; Berger,Erika; Kisseberth, William C.; Brown, Megan E.; Lana, Susan E.; Weishaar, Kristen; Flesner, Brian K.; Bryan, Jeffrey N.; Vail, David M.; Burton, Jenna H.; Willcox, Jennifer L.; Mutsaers, Anthony J.; Woods, J. Paul; Northrup, Nicole C.; Saba, Corey; Curran, Kaitlin M.; Leeper, Haley; Wilson-Robles, Heather; Wustefeld-Janssens, Brandan G.; Lindley, Stephanie; Smith, Annette N.; Dervisis, Nikolaos; Klahn, Shawna; Higginbotham, Mary Lynn; Wouda, Raelene M.; Krick, Erika; Mahoney, Jennifer A.; London, Cheryl A.; Barber, Lisa G.; Balkman, Cheryl E.; McCleary-Wheeler, Angela L.; Suter, Steven E.; Martin, Olya; Borgatti, Antonella; Burgess, Kristine; Childress, Michael O.; Fidel, Janean L.; Allstadt, Sara D.; Gustafson, Daniel L.; Selmic, Laura E.; Khanna, Chand; Fan, Timothy M.
  3. CLINICAL CANCER RESEARCH. 2021, Jun 1; 27: 3005-3016.
  1. 25.   Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential
  2. Fermaintt, Charles S.; Peramuna, Thilini; Cai, Shengxin; Takahashi-Ruiz, Leila; Essif, Jacob Nathaniel; Grant, Corena V.; O'Keefe,Barry; Mooberry, Susan L.; Cichewicz, Robert H.; Risinger, April L.
  3. Cancers. 2021, JUN; 13(11):
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