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  1. 1.   Induction of Kaposi Sarcoma Associated Herpesvirus-encoded Thymidine Kinase (ORF21) by X-Box Binding Protein-1
  2. Wang, Victoria; Davis, David A; Deleage,Claire; Brands,Catherine; Choi, Hong S; Haque, Muzammel; Yarchoan, Robert
  3. Journal of virology. 2020, MAR; 94(5):
  1. 2.   D-(+)-iso-methanocarbathymidine: A high-affinity substrate for herpes simplex virus 1 thymidine kinase
  2. Comin, M. J.; Vu, B. C.; Boyer, P. L.; Liao, C.; Hughes, S. H.; Marquez, V. E.
  3. Chemmedchem. 2008 3(7): 1129-1134.
  1. 3.   Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues
  2. Lisco, A.; Vanpouille, C.; Tchesnokov, E. P.; Grivel, J. C.; Biancotto, A.; Brichacek, B.; Elliott, J.; Fromentin, E.; Shattock, R.; Anton, P.; Gorelick, R.; Balzarini, J.; McGuigan, C.; Derudas, M.; Gotte, M.; Schinazi, R. F.; Margolis, L.
  3. Cell Host & Microbe. 2008 4(3): 260-270.
  1. 4.   Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963
  2. Thorne, S. H.; Hwang, T. H. H.; O'Gorman, W. E.; Bartlett, D. L.; Sei, S.; Kanji, F.; Brown, C.; Werier, J.; Cho, J. H.; Lee, D. E.; Wang, Y.; Bell, J.; Kirn, D. H.
  3. Journal of Clinical Investigation. 2007, Nov; 117(11): 3350-3358.
  1. 5.   The history of N-methanocarbathymidine: The investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent
  2. Marquez, V. E.; Hughes, S. H.; Sei, S.; Agbaria, R.
  3. Antiviral Research. 2006, Sep; 71(2-3): 268-275.
  1. 6.   Potent antiviral activity of North-methanocarbathymidine against Kaposi's sarcoma-associated herpesvirus
  2. Zhu, W. M.; Burnette, A.; Dorjsuren, D.; Roberts, P. E.; Huleihel, M.; Shoemaker, R. H.; Marquez, V. E.; Agbaria, R.; Sei, S.
  3. Antimicrobial Agents and Chemotherapy. 2005, DEC; 49(12): 4965-4973.
  1. 7.   Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: A chemical approach
  2. Marquez, V. E.; Choi, Y.; Comin, M. J.; Russ, P.; George, C.; Huleihel, M.; Ben-Kasus, T.; Agbaria, R.
  3. Journal of the American Chemical Society. 2005, NOV 2; 127(43): 15145-15150.
  1. 8.   Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
  2. Ben-Kasus, T.; Ben-Zvi, Z.; Marquez, V. E.; Kelley, J. A.; Agbaria, R.
  3. Biochemical Pharmacology. 2005, JUL 1; 70(1): 121-133.
  1. 9.   Azidothymidine inhibits NF-kappa B and induces Epstein-Barr virus gene expression in Burkitt lymphoma
  2. Kurokawa, M.; Ghosh, S. K.; Ramos, J. C.; Mian, A. M.; Toomey, N. L.; Cabral, L.; Whitby, D.; Barber, G. N.; Dittmer, D. P.; Harrington, W. J.
  3. Blood. 2005, JUL 1; 106(1): 235-240.
  1. 10.   Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture
  2. Huleihel, M.; Talishanisky, M.; Ford, H.; Marquez, V. E.; Kelley, J. A.; Johns, D. G.; Agbaria, R.
  3. International Journal of Antimicrobial Agents. 2005, MAY; 25(5): 427-432.
  1. 11.   Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker
  2. Marquez, V. E.; Ben Kasus, T.; Barchi, J. J.; Green, K. M.; Nicklaus, M. C.; Agbaria, R.
  3. Journal of the American Chemical Society. 2004 126(2): 543-549.
  1. 12.   Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)- methanocarbathymine
  2. Russ, P.; Schelling, P.; Scapozza, L.; Folkers, G.; De Clercq, E.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2003 46(23): 5045-5054.
  1. 13.   Metabolic pathways of N-methanocarbathymidine, a novel antiviral agent, in native and herpes simplex virus type 1 infected Vero cells
  2. Zalah, L.; Huleihel, M.; Manor, E.; Konson, A.; Ford, H.; Marquez, V. E.; Johns, D. G.; Agbaria, R.
  3. Antiviral Research. 2002 55(1): 63-75.
  1. 14.   Biosynthetic ganciclovir triphosphate: Its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells
  2. Agbaria, R.; Candotti, F.; Kelley, J. A.; Hao, Z.; Johns, D. G.; Cooney, D. A.; Blaese, R. M.; Ford, H.
  3. Biochemical and Biophysical Research Communications. 2001 289(2): 525-530.
  1. 15.   Cloning of the murine Drm gene (Cktsf1b1)and characterization of its oncogene suppressible promoter
  2. Zhang, Q.; Topol, L. Z.; Athanasiou, M.; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Blair, D. G.
  3. Cytogenetics and Cell Genetics. 2000 89(3-4): 242-+.
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