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  1. 1.   TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function
  2. Alam, Muhammad S; Gaida, Matthias M; Witzel, Hagen R; Otsuka, Shizuka; Abbasi, Aamna; Guerin,Theresa; Abdelmaksoud, Abdalla; Wong, Nathan; Cam,Maggie; Kozlov,Serguei; Ashwell, Jonathan D
  3. Cell Reports. Medicine. 2024, Aug 19; 101696.
  1. 2.   Combinational delivery of TLR4 and TLR7/8 agonist enhanced the therapeutic efficacy of immune checkpoint inhibitors to colon tumor
  2. Wang, Mengjiao; Wan, Quan; Wang, Chenglv; Jing, Qianyu; Nie, Yujie; Zhang, Xiangyan; Chen, Xin; Yang,De; Pan, Runsang; Li, Linzhao; Zhu, Lan; Gui, Huan; Chen, Shuanghui; Deng, Yuezhen; Chen, Tao; Nie, Yingjie
  3. Molecular and Cellular Biochemistry. 2024, Mar 20;
  1. 3.   Anti-TNFR2 enhanced the antitumor activity of a new HMGN1/3M-052 stimulated dendritic cell vaccine in a mouse model of colon cancer
  2. Zhu, Lan; Zhang, Xiangyan; Chen, Xin; Yang,De; Nie, Yujie; Pan, Runsang; Li, Linzhao; Wang, Chenglv; Gui, Huan; Chen, Shuanghui; Jing, Qianyu; Wang, Mengjiao; Nie, Yingjie
  3. Biochemical and Biophysical Research Communications. 2023, Feb 16; 653: 106-114.
  1. 4.   TNF plays a crucial role in inflammation by signaling via T cell TNFR2
  2. Alam, Muhammad S.; Otsuka, Shizuka; Wong,Nathan; Abbasi, Aamna; Gaida, Matthias M.; Fan, Yu; Meerzaman, Daoud; Ashwell, Jonathan D.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2021, Dec 14; 118(50):
  1. 5.   A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer
  2. Jiang, Mengmeng; Liu,Jia; Yang,De; Tross,Debra; Li, Ping; Chen, Fengyang; Alam,Md Masud; Faustman, Denise L; Oppenheim,Joost; Chen, Xin
  3. International immunopharmacology. 2021, Nov 15; 101(Pt A): 108345.
  1. 6.   Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells
  2. He, Tianzhen; Yang,De; Li, Xiao-Qing; Jiang, Mengmeng; Islam, Md Sahidul; Chen, Shaokui; Chen, Yibo; Yang, Yang; Chou, Chon-Kit; Trivett,Anna; Oppenheim,Joost; Chen, Xin
  3. Science advances. 2020, Sep; 6(40): pii: eaba6584.
  1. 7.   Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages
  2. Bayik, Defne; Tross, Debra; Klinman, Dennis
  3. Frontiers in immunology. 2018, Mar 26; 9: 608.
  1. 8.   Association ofTNFRSF1BPromoter Polymorphisms with Human Disease: Further Studies Examining T-Regulatory Cells Are Required
  2. Li, Hongchuan; Anderson, Steve
  3. Frontiers in immunology. 2018, Mar 6; 9: 443.
  1. 9.   Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
  2. Chen, X.; Oppenheim, J. J.
  3. Febs Letters. 2011, Dec; 585(23): 3611-3618.
  1. 10.   The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4(+) FoxP3(+) regulatory T cells
  2. Chen, X.; Oppenheim, J. J.
  3. Immunology. 2011, Aug; 133(4): 426-433.
  1. 11.   Prediagnostic Serum Levels of Cytokines and Other Immune Markers and Risk of Non-Hodgkin Lymphoma
  2. Purdue, M. P.; Lan, Q.; Bagni, R.; Hocking, W. G.; Baris, D.; Reding, D. J.; Rothman, N.
  3. Cancer Research. 2011, Jul; 71(14): 4898-4907.
  1. 12.   TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40
  2. Hamano, R.; Huang, J. Q.; Yoshimura, T.; Oppenheim, J. J.; Chen, X.
  3. European Journal of Immunology. 2011, Jul; 41(7): 2010-2020.
  1. 13.   Effect of North Bicyclo[3.1.0]hexane 2 '-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  2. Terrazas, M.; Ocampo, S. M.; Perales, J. C.; Marquez, V. E.; Eritja, R.
  3. Chembiochem. 2011, May; 12(7): 1056-1065.
  1. 14.   Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine
  2. Libutti, S. K.; Paciotti, G. F.; Byrnes, A. A.; Alexander, H. R.; Gannon, W. E.; Walker, M.; Seidel, G. D.; Yuldasheva, N.; Tamarkin, L.
  3. Clinical Cancer Research. 2010, Dec; 16(24): 6139-6149.
  1. 15.   Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis
  2. Sangaletti, S.; Tripodo, C.; Ratti, C.; Piconese, S.; Porcasi, R.; Salcedo, R.; Trinchieri, G.; Colombo, M. P.; Chiodoni, C.
  3. Cancer Research. 2010, Oct; 70(20): 7764-7775.
  1. 16.   Downregulation of Programmed Cell Death 4 by Inflammatory Conditions Contributes to the Generation of the Tumor Promoting Microenvironment
  2. Yasuda, M.; Schmid, T.; Rubsamen, D.; Colburn, N. H.; Irie, K.; Murakami, A.
  3. Molecular Carcinogenesis. 2010, Sep; 49(9): 837-848.
  1. 17.   A Custom 148 Gene-Based Resequencing Chip and the SNP Explorer Software: New Tools to Study Antibody Deficiency
  2. Wang, H. Y.; Gopalan, V.; Aksentijevich, I.; Yeager, M.; Ma, C. A.; Mohamoud, Y. A.; Quinones, M.; Matthews, C.; Boland, J.; Niemela, J. E.; Torgerson, T. R.; Giliani, S.; Uzel, G.; Orange, J. S.; Shapiro, R.; Notarangelo, L.; Ochs, H. D.; Fleisher, T.; Kastner, D.; Chanock, S. J.; Jain, A.
  3. Human Mutation. 2010, Sep; 31(9): 1080-1088.
  1. 18.   Effect of Host Genetics on Incidence of HIV Neuroretinal Disorder in Patients With AIDS
  2. Sezgin, E.; Hendrickson, S. L.; Jabs, D. A.; Van Natta, M. L.; Lewis, R. A.; Troyer, J. L.; O'Brien, S. J.; Grp, S. R.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2010, Aug; 54(4): 343-351.
  1. 19.   Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization
  2. Patel, V.; Valentin, A.; Kulkarni, V.; Rosati, M.; Bergamaschi, C.; Jalah, R.; Alicea, C.; Minang, J. T.; Trivett, M. T.; Ohlen, C.; Zhao, J.; Robert-Guroff, M.; Khan, A. S.; Draghia-Akli, R.; Felber, B. K.; Pavlakis, G. N.
  3. Vaccine. 2010, Jul; 28(30): 4827-4836.
  1. 20.   Transcription Factor E2F1 Suppresses Dendritic Cell Maturation
  2. Fang, F.; Wang, Y.; Li, R.; Zhao, Y.; Guo, Y.; Jiang, M.; Sun, J.; Ma, Y.; Ren, Z. J.; Tian, Z. G.; Wei, F.; Yang, D.; Xiao, W. H.
  3. Journal of Immunology. 2010, Jun; 184(11): 6084-6091.
  1. 21.   Human beta-Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2
  2. Rohrl, J.; Yang, D.; Oppenheim, J. J.; Hehlgans, T.
  3. Journal of Immunology. 2010, Jun; 184(12): 6688-6694.
  1. 22.   Bortezomib Sensitizes Human Esophageal Squamous Cell Carcinoma Cells to TRAIL-Mediated Apoptosis via Activation of Both Extrinsic and Intrinsic Apoptosis Pathways
  2. Seki, N.; Toh, U.; Sayers, T. J.; Fujii, T.; Miyagi, M.; Akagi, Y.; Kusukawa, J.; Kage, M.; Shirouzu, K.; Yamana, H.
  3. Molecular Cancer Therapeutics. 2010, Jun; 9(6): 1842-1851.
  1. 23.   Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology
  2. Wang, S. S.; Abdou, A. M.; Morton, L. M.; Thomas, R.; Cerhan, J. R.; Gao, X. J.; Cozen, W.; Rothman, N.; Davis, S.; Severson, R. K.; Bernstein, L.; Hartge, P.; Carrington, M.
  3. Blood. 2010, Jun; 115(23): 4820-4823.
  1. 24.   Bortezomib Sensitizes Human Renal Cell Carcinomas to TRAIL Apoptosis through Increased Activation of Caspase-8 in the Death-Inducing Signaling Complex
  2. Brooks, A. D.; Jacobsen, K. M.; Li, W. Q.; Shanker, A.; Sayers, T. J.
  3. Molecular Cancer Research. 2010, May; 8(5): 729-738.
  1. 25.   Co-expression of TNFR2 and CD25 identifies more of the functional CD4(+)FOXP3(+) regulatory T cells in human peripheral blood
  2. Chen, X.; Subleski, J. J.; Hamano, R.; Howard, O. M. Z.; Wiltrout, R. H.; Oppenheim, J. J.
  3. European Journal of Immunology. 2010, Apr; 40(4): 1099-1106.
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