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  1. 1.   The Recognition of and Reactions to Nucleic Acid Nanoparticles by Human Immune Cells
  2. Bila, Dominika; Radwan, Yasmine; Dobrovolskaia,Marina; Panigaj, Martin; Afonin, Kirill A.
  3. MOLECULES. 2021, Jul 12; 26(14):
  1. 2.   BCAP Regulates Dendritic Cell Maturation Through the Dual-Regulation of NF-kappa B and PI3K/AKT Signaling During Infection
  2. Miao, Yuhui; Jiang, Ming; Qi, Lu; Yang,De; Xiao, Weihua; Fang, Fang
  3. FRONTIERS IN IMMUNOLOGY. 2020, Feb 18; 11
  1. 3.   PD-1 blockade and TLR7 activation lack therapeutic benefit in chronic SIV-infected macaques on antiretroviral therapy
  2. Bekerman, Elena; Hesselgesser, Joseph; Carr, Brian; Nagel, Mark; Hung, Magdeleine; Wang, Adele; Stapleton, Lance; von Gegerfelt, Agneta; Elyard, Hanne Andersen; Lifson,Jeffrey; Geleziunas, Romas
  3. Antimicrobial agents and chemotherapy. 2019, NOV; 63(11): pii: AAC.01163-19.
  1. 4.   Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells
  2. Hong, Enping; Halman, Justin R; Shah, Ankit; Cedrone,Edward; Truong, Nguyen; Afonin, Kirill A; Dobrovolskaia,Marina
  3. Molecules (Basel, Switzerland). 2019, Mar 2; 24(6): pii: E1094.
  1. 5.   Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery
  2. Gregg, Kelsey A.; Harberts, Erin; Gardner, Francesca M.; Pelletier, Mark R.; Cayatte, Corinne; Yu, Li; McCarthy, Michael P.; Marshall, Jason; Ernst, Robert K.
  3. MBIO. 2017, May-Jun; 8(3):
  1. 6.   Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA
  2. Berg, R. K.; Melchjorsen, J.; Rintahaka, J.; Diget, E.; Soby, S.; Horan, K. A.; Gorelick, R. J.; Matikainen, S.; Larsen, C. S.; Ostergaard, L.; Paludan, S. R.; Mogensen, T. H.
  3. Plos One. 2012, Jan; 7(1):
  1. 7.   Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons
  2. Qi, J.; Buzas, K.; Fan, H. T.; Cohen, J. I.; Wang, K. N.; Mont, E.; Klinman, D.; Oppenheim, J. J.; Howard, O. M. Z.
  3. Journal of Immunology. 2011, Jun; 186(11): 6417-6426.
  1. 8.   CpG DNA as a vaccine adjuvant
  2. Bode, C.; Zhao, G.; Steinhagen, F.; Kinjo, T.; Klinman, D. M.
  3. Expert Review of Vaccines. 2011, Apr; 10(4): 499-511.
  1. 9.   TLR-based immune adjuvants
  2. Steinhagen, F.; Kinjo, T.; Bode, C.; Klinman, D. M.
  3. Vaccine. 2011, Apr; 29(17): 3341-3355.
  1. 10.   TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release
  2. Smrz, D.; Iwaki, S.; McVicar, D. W.; Metcalfe, D. D.; Gilfillan, A. M.
  3. European Journal of Immunology. 2010, Dec; 40(12): 3557-3569.
  1. 11.   Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin
  2. Tewary, P.; Yang, D.; de la Rosa, G.; Li, Y. N.; Finn, M. W.; Krensky, A. M.; Clayberger, C.; Oppenheim, J. J.
  3. Blood. 2010, Nov 4; 116(18): 3465-3474.
  1. 12.   Type I interferon: friend or foe?
  2. Trinchieri, G.
  3. Journal of Experimental Medicine. 2010, Sep; 207(10): 2053-2063.
  1. 13.   Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands
  2. Mureith, M. W.; Chang, J. J.; Lifson, J. D.; Ndung'u, T.; Altfeld, M.
  3. Aids. 2010, Jul; 24(12): 1841-1848.
  1. 14.   Short- and long-term changes in gene expression mediated by the activation of TLR9
  2. Klaschik, S.; Tross, D.; Shirota, H.; Klinman, D. M.
  3. Molecular Immunology. 2010, Mar; 47(6): 1317-1324.
  1. 15.   Toll-like receptors in inflammation, infection and cancer
  2. Chen, K. Q.; Huang, J.; Gong, W. H.; Iribarren, P.; Dunlop, N. M.; Wang, J. M.
  3. International Immunopharmacology. 2007, Oct; 7(10): 1271-1285.
  1. 16.   Functional genomics of innate host defense molecules in normal human monocytes in response to Aspergillus fumigatus
  2. Cortez, K. J.; Lyman, C. A.; Kottilil, S.; Kim, H. S.; Roilides, E.; Yang, J.; Fullmer, B.; Lempicki, R.; Walsh, T. J.
  3. Infection and Immunity. 2006, Apr; 74(4): 2353-2365.
  1. 17.   A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappa B and enhanced IRF-3/STAT1 activation)
  2. Biswas, S. K.; Gangi, L.; Paul, S.; Schioppa, T.; Saccani, A.; Sironi, M.; Bottazzi, B.; Doni, A.; Vincenzo, B.; Pasqualini, F.; Vago, L.; Nebuloni, M.; Mantovani, A.; Sica, A.
  3. Blood. 2006, Mar; 107(5): 2112-2122.
  1. 18.   The adaptive immune response in neonatal cerebral white matter damage
  2. Leviton, A.; Dammann, O.; Durum, S. K.
  3. Annals of Neurology. 2005, DEC; 58(6): 821-828.
  1. 19.   Cutting edge: Expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex
  2. Medvedev, A. E.; Thomas, K.; Awomoyi, A.; Kuhns, D. B.; Gallin, J. I.; Li, X. X.; Vogel, S. N.
  3. Journal of Immunology. 2005, JUN 1; 174(11): 6587-6591.
  1. 20.   Transcriptional regulator CTCF controls human interleukin 1 receptor-associated kinase 2 promoter
  2. Kuzmin, I.; Geil, L.; Gibson, L.; Cavinato, T.; Loukinov, D.; Lobanenkov, V.; Lerman, M. I.
  3. Journal of Molecular Biology. 2005, FEB 18; 346(2): 411-422.
  1. 21.   CpG Oligodeoxynucleotides as Adjuvants for Clinical Use
  2. Shirota, H.; Klinman, Dennis
  3. 2017; (Immunopotentiators in Modern Vaccines, 2nd Edition): 163-198.
  1. 22.   CpG Oligonucleotides as Vaccine Adjuvants
  2. Kayraklioglu, Neslihan; Horuluoglu, Begum; Klinman,Dennis
  3. DNA VACCINES. 2021 2197: 51-85.
  1. 23.   Detection of Nanoparticles' Ability to Stimulate Toll-Like Receptors Using HEK-Blue Reporter Cell Lines
  2. Cedrone,Edward; Dobrovolskaia,Marina
  3. Methods in Molecular Biology (Clifton, N.J.). 2023 2709: 241-251.
  1. 24.   LTX-315 triggers anticancer immunity by inducing MyD88-dependent maturation of dendritic cells
  2. Li, Xiao-Qing; Yamazaki, Takahiro; He, Tianzhen; Alam, Md Masud; Liu, Jia; Trivett,Anna; Sveinbjørnsson, Baldur; Rekdal, Øystein; Galluzzi, Lorenzo; Oppenheim, Joost J; Yang,De
  3. Frontiers in Immunology. 2024 15: 1332922.
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